Height
was approved by: chear-kb:PER-Jeanette-Stingone
type: QuantityVariable
subclass of: Anthropometry
definition: Height
type: Class

Reproductive Health
definition: Reproductive Health Indicator Class
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class
subclass of: StudyIndicator

2, 3, 4, 5-Tetrachlorophenol
subclass of: Environmental Phenol
type: Class
definition: PHYSICAL DESCRIPTION: Needles (from petroleum ether, ligroin) or beige solid. (NTP, 1992)
notation: TeCP2345

Insurance Type
type: QualityVariable
subclass of: Insurance
definition: Insurance Type
type: Class

Monomethylarsonic Acid
notation: Monomethylarsonic Acid
subclass of: Arsenic Species
type: Class

Interleukin-21
notation: IL21
type: Class
subclass of: SIO_010043

Head Of Household
subclass of: Demographic
type: Class
definition: The Person is the head of Household
label: Head of Household
subclass of: SIO_000016
subclass of: Restriction
  all values from: Class
    intersection of: Household
  on property: inRelationTo
definition: Head of Household is a filing status for individual United States taxpayers. To use the Head of Household filing status, a taxpayer must: (1) Be unmarried or considered unmarried at the end of the year (2) Have paid more than half the cost of keeping up a home for the tax year (either one's own home or the home of a qualifying parent) (3) Usually have a qualifying person who lived with the head in the home for more than half of the tax year unless the qualifying person is a dependent parent.
was approved by: chear-kb:PER-Jeanette-Stingone

Value less than LOD
subclass of: SIO_001167
type: Class

N-A-S-(3-hydrxprpl-1-metl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCPMM

all-cis-icosa-8, 11, 14-trienoic acid
notation: C203N6
subclass of: Fatty Acid
type: Class
definition: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.

abnormal cell
subclass of: Cell
type: Class

docosanoic acid
type: Class
subclass of: Fatty Acid
definition: A straight-chain, C22, long-chain saturated fatty acid.
notation: C220

N-Ace-S-(2-Hydroxyethyl)-L-cys(ng/mL)
notation: VOCHEM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

HHEAR
imports: uo.owl
version IRI: http://purl.org/twc/HHEAR/1.0
imports: sio.owl
imports: prov
type: Ontology
imports: cogat
imports: stato.owl
comment: The Human Health Exposure Analysis Resource (HHEAR) measures exposures that cover the breadth of the “exposome,” which encompasses all environmental exposures including chemical, physical, and biological stressors, as well as lifestyle and social environments, from conception through adulthood. Read more at: https://hhearprogram.org
imports: cmo.owl
imports: cl-basic.owl

Inorganic Mercury (Hg2+)
type: Class
notation: Hg2
subclass of: Mercury Species

second
type: SIO_000074
notation: s

N-Acetyl-S-(2-Carbxyethyl)-L-Cys(ng/mL)
subclass of: Volatile Organic Compound
type: Class
notation: VOCCEM
editorial note: To Do: align with CHEBI.

Interleukin-5
notation: IL5
subclass of: SIO_010043
type: Class

Maternal Weight Gain
subclass of: Weight
subclass of: Pregnancy Characteristic
definition: The amount of weight gained during a pregnacy.
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class

dimethylthiophosphate
notation: DMTP
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.

pascal second
type: SIO_000074
notation: Pas

millisecond
notation: ms
type: SIO_000074

Assisted Reproductive Therapy
notation: 7
subclass of: Pregnancy Characteristic
type: QualityValue
type: Class

beta-hexachlorocyclohexane
type: Class
notation: BHCH
subclass of: Organochlorine Compound

Failed positive control
subclass of: SIO_001167
type: Class

No Insurance / Self-funded
type: QualityValue
notation: 89
type: Class
subclass of: Private Insurance or Self Pay

Healthcare Access
type: Class
subclass of: StudyIndicator
definition: Healthcare Access

Butyl paraben
subclass of: Paraben
definition: Butylparaben is a Standardized Chemical Allergen. The physiologic effect of butylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of butylparaben is Allergens.
type: Class
notation: BuPB

Did Not Consume Alcohol
type: QualityValue
subclass of: Alcohol Use
notation: 53
type: Class

Non-smoker
notation: 59
subclass of: Smoking Status
definition: Doesn't smoker cigarettes.
type: QualityValue
type: Class

Pregnancy Sample
subclass of: Biospecimen
definition: A sample that is taken at or near pregnancy or birth.
type: Class

Gel Electrophoresis
type: Class
subclass of: SIO_001007
definition: Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.

Elementary School
type: Class
type: QualityValue
notation: 15
subclass of: Some Elementary School
was approved by: chear-kb:PER-Jim-McCusker
definition: Finished Elementary School

PCB180
subclass of: Polychlorobiphenyl
type: Class
notation: PCB180

Active Smoker
editorial note: How is this different from "smoker'?
type: QualityValue
notation: 2
type: Class
subclass of: Smoking Status
definition: The quality of actively smoking.

Haptoglobin
notation: HAPTOGLOBIN
subclass of: SIO_010043
type: Class

N-Ace-S-(2-hydroxypropyl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCHP2

centiRay
type: SIO_000074
notation: cR

Tri-Cell DMA-80 Direct Mercury Analyzer
definition: The DMA-80 is based on the principles of sample thermal decomposition, mercury amalgamation and atomic absorption detection. The DMA-80 has been used to develop the US EPA method 7473 (Mercury in solids and solutions by thermal decomposition, amalgamation, and atomic absorption spectrophotometry). It is furthermore compliant with ASTM method D-6722-01 (Total mercury in coal and coal combustion residues) and ASTM method D-7623-10 (Total mercury in crude oil).
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: Direct Mercury Analyzer

electric field strength unit
notation: Efs
type: SIO_000074

N-Acetyl-S-(phenyl)-L-cysteine(ng/mL)
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class
notation: VOCPMA

monoethyl phthalate (DEP)
type: Class
notation: MEP
subclass of: Phthalate

eosinophils per high-power field
subclass of: SIO_000794
type: Class
comment: A histological count of the eosinophils in a high-power microscopic field of view, or 0.158 mm^2 (x400).

mono-n-butylphthalate (BzBP, DnBP)
notation: MnBP
type: Class
subclass of: Phthalate

mono (7-COOH-2-methyloctyl) phthalate
type: Class
subclass of: Phthalate
notation: MCOMOP

Liquid Chromatography–Mass Spectrometer
subclass of: Mass Spectrometer
definition: An analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin.
subclass of: Liquid Chromatography Instrument
type: Class
was approved by: chear-kb:PER-Jim-McCusker

Interleukin-10
subclass of: Biological Response
subclass of: SIO_010043
notation: IL10
definition: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
type: Class

DVD Player Count
type: QuantityVariable
subclass of: Household Appliance Count
definition: Number of devices in the home that play DVDs.
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

millimole
notation: mmol
type: SIO_000074

mass density unit
notation: mdu
type: SIO_000074

Volatile Organic Compound
subclass of: Targeted Analyte
type: Class

Education Grade 5
definition: Finished grade 5
notation: 117
type: QualityValue
type: Class
subclass of: Some Middle School

t, t-Muconic acid(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCMUC
type: Class

Previous Smoker
type: Class
subclass of: Smoking Status
notation: 78
type: QualityValue
definition: The quality of having smoked in the past.

microcurie per milliliter
notation: µcurie/ml
type: SIO_000074

Visit
definition: The time interval of an encounter between a study subject and a study administrator.
type: Class
subclass of: SIO_000417

72 kDa type IV collagenase
notation: IL33
notation: MMP2
label: Interleukin-33
subclass of: SIO_010043
type: Class

lux
notation: lx
type: SIO_000074

Styrene
type: Class
subclass of: Volatile Organic Compound
definition: STYRENE is a colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.
notation: STY

Mercury
subclass of: Metal
notation: Hg
definition: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
type: Class

Bisulfite Pyrosequencing
type: Class
subclass of: Nucleic Acid Sequencing

Mercury Species
subclass of: Targeted Analyte
type: Class

Bismuth
notation: Bi
type: Class
subclass of: Metal
definition: BISMUTH is a metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.

Aluminum
notation: Al
type: Class
subclass of: Metal
definition: ALUMINUM is a metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.

milliliter per cubic meter
notation: ml/m3
type: SIO_000074

3, 5, 6-trichloro-2-pyridinol
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
notation: TCP

Floor Type
type: Class
subclass of: Housing Characteristic
definition: Type of material that makes up the floor.
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityVariable
subclass of: SIO_000004

N-Acetyl-S-(2, 2-dichlorovinyl)-L-cysteine
subclass of: Volatile Organic Compound
notation: DCVMA22
type: Class
editorial note: To Do: align with CHEBI.

Planned Caesarian Section
type: QualityValue
notation: 18
subclass of: Caesarian Section
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Planned caesarian section.

Route Of Delivery
type: QualityVariable
type: Class
subclass of: Delivery Characteristics

Reichert AR200 Handheld Digital Refractometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class
definition: Lightweight digital refractometer designed for the food, beverage, agricultural, industrial-fluid, chemical, petrochemical, pharmaceutical, medical, and plastic industries.
subclass of: Refractometer

Education Grade 6
type: QualityValue
notation: 118
definition: Finished grade 6
subclass of: Some Middle School
type: Class

millicurie
notation: mCi
type: SIO_000074

Environmental Exposure
definition: EnvironmentalExposure Indicator Class
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class
editorial note: may need to refine this name in order to clearly differentiate from environmental exposures measured within CHEAR. Perhaps ExternalEnvironmental Exposure. Ok for now but we may want to discuss.
subclass of: StudyIndicator

No Anti Malarial Use
type: QualityValue
subclass of: Prescription Medication and Dietary Supplements
notation: 140
type: Class

Physical and Mental Assessment
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Physical and Mental Assessments Indicator Class
subclass of: StudyIndicator

nanometer
type: SIO_000074
notation: nm

Education Grade 4
subclass of: Elementary School
type: QualityValue
notation: 116
type: Class
definition: Finished grade 4

Ethnicity
subclass of: Demographic
type: Class
type: QualityVariable
subclass of: SIO_000475
was approved by: chear-kb:PER-Jeanette-Stingone

Steroid Treatment form of Medical Therapy
type: QualityValue
definition: Had a form of treatment which uses steroids.
notation: 28
subclass of: Medical Therapy Procedure
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class

4-nitrophenol
notation: PNP

PCB118
type: Class
subclass of: Polychlorobiphenyl
notation: PCB118

Active Non-Tobacco Smoker
type: QualityValue
definition: Active Non-Tobacco Smoker
subclass of: Active Smoker
type: Class
notation: 1

milligram
type: SIO_000074
notation: mg

PCB138
type: Class
notation: PCB138
subclass of: Polychlorobiphenyl

oleic acid
definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
type: Class
notation: C181N9
subclass of: Fatty Acid

megabasepair
notation: Mb
type: SIO_000074

Higher Education
subclass of: Education
definition: College or university education beyond the successful completion of high school or grammar school, or the attainment of an approved equivalent
type: Class
notation: 31
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityValue

milligram per deciliter
notation: mg/dl
type: SIO_000074

1-hydroxynaphthalene
subclass of: PAH
notation: NAP1
type: Class

MicroPEM
definition: The MicroPEM device monitors individual exposures to very fine airborne particles—or particulate matter—at two sizes. PM10 has a diameter of less than 10 micrometers (PM10), which is approximately 1/30th the size of a human hair, and PM2.5, which at diameters of less than 2.5 micrometers, is even smaller.
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: Exposure Monitoring Instrument

Biological Relative
type: Class
subclass of: Relative
definition: Being from the same biological kinship as another person. In that aspect, consanguinity is the quality of being descended from the same ancestor as another person.

international units per litre
notation: IU/L
type: SIO_000074

micromole per liter
notation: µmol/L
type: SIO_000074

Marital Status
subclass of: SIO_001326
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityVariable
subclass of: Demographic
type: Class
definition: A person's current conjugal status.

Diet Quantity
type: Class
definition: A quantity relating to diet and nutrition.
subclass of: SIO_000052
type: QuantityVariable
subclass of: Diet and Nutrition
was approved by: chear-kb:PER-Jeanette-Stingone
editorial note: What differentiated diet from nutrition? That is why is this needed since we have the DietAndNutrition Class

alpha-hexachlorocyclohexane
subclass of: Organochlorine Compound
notation: AHCH
type: Class

Nucleic Acid Sequencing
subclass of: SIO_001007
type: Class

Lipemic sample, clarified before running
type: Class
subclass of: SIO_001167

Neptunium
definition: Neptunium. A radioactive element of the actinide metals family. NEPTUNIUM has the atomic symbol Np, atomic number 93, and atomic weight 237.
notation: Np
subclass of: Metal
type: Class

Vitamin D
type: Class
subclass of: Diet and Nutrition
subclass of: Biomolecule
definition: Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body.

No Sickle Cell Anemia
notation: 138
type: Class
subclass of: Medical History
type: QualityValue

Waist
definition: The waist is the part of the abdomen between the rib cage and hips. On people with slim bodies, the waist is the narrowest part of the torso.
subclass of: SIO_010046
type: Class

mild eosinophilic esophagitis
comment: Eosinophilic esophagitis is mild when a biopsy of the esophagus reveals a count of 15-25 eosinophils per high-power field area, or 0.158 mm^2 (400x).
type: Class
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
subclass of: eosinophilic esophagitis

Anthropometry
subclass of: StudyIndicator
definition: Attributes pertaining to the scientific study of the measurements and proportions of the human body.
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

kilogram per mole
type: SIO_000074
notation: kg/mol

Underweight/Normal
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
type: QualityValue
subclass of: Body Weight Quality
notation: 100
type: Class

Drinking Water
subclass of: Environmental Material
definition: Drinking water is water which may be consumed by humans with no adverse effects on their health.
definition: Drinking Water
type: Class

Adult
definition: Refers to a person above a threshold age.
subclass of: Demographic
type: Class
subclass of: Developmental Quality
type: QualityValue
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 3

N-Acetyl-S-(2, 4-dimethylphenyl)-L-cysteine + N-Acetyl-S-(2, 5-dimethylphenyl)-L-cysteine + N-Acetyl-S-(3, 4-dimethylphenyl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
notation: DPMA
editorial note: To Do: align with CHEBI.

Widowed
definition: Indicates a person who is no longer married because of the death of his/her spouse and has not remarried.
type: Class
subclass of: Unmarried
type: QualityValue
notation: 39

2, 2', 4, 4'-tetrahydroxybenzophenone
notation: BP2

Study Baseline
definition: Point in study set to initial point.
type: Class
subclass of: SIO_000417

Normal Weight
type: QualityValue
subclass of: Underweight/Normal
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
definition: 18.5<=BMI<=25
notation: 61
subclass of: Body Weight Quality
type: Class

Result repeated with diluted sample
subclass of: SIO_001167
type: Class

Tellurium
notation: Te
type: Class
subclass of: Metal
definition: Tellurium. An element that is a member of the chalcogen family. TELLURIUM has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.

2, 2', 4, 4', 5, 5'-Hexabromobiphenyl
type: Class
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.
notation: PBB153

Sputum
subclass of: Bodily Fluid
definition: Matter ejected from the lungs, bronchi, and trachea, through the mouth. [database_cross_reference: Dorlands_Medical_Dictionary:MerckSource]
type: Class

Body Mass Index
definition: A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000052
type: QuantityVariable
editorial note: Should we note that this is derived from height and weight? JS: I think so
subclass of: Anthropometry
type: Class
subclass of: Class
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Height
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: SIO_000279

picoliter
notation: pl
type: SIO_000074

PCB28
type: Class
notation: PCB28
subclass of: Polychlorobiphenyl

2, 2', 3, 4, 4'-Pentabromodiphenyl ether
notation: BDE85
type: Class
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.

magnetic flux density unit
notation: MFDU
type: SIO_000074

N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
notation: AAMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

1-hydroxybenzo[c]-phenanthrene
subclass of: PAH
type: Class
notation: BCP1

cubic meter per mole
notation: m3/mol
type: SIO_000074

Descendant
subclass of: Relative
definition: The child of a human, or any grandchild, great-grandchild, and so on.
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Ancestor
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

SIO_010058
type: QualityValue
notation: 131

Long Range Polymerase Chain Reaction
type: Class
was approved by: chear-kb:PER-Jim-McCusker
subclass of: Polymerase Chain Reaction
definition: Amplification of DNA lengths that cannot typically be amplified using routine PCR methods or reagents. For simple DNA templates, polymerases optimized for Long Range PCR can amplify up to 30 kb and beyond. For complex, genomic templates, 20 kb is a typical target.

Retinopathy
subclass of: Phenotype
type: QualityValue
definition: Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.
notation: 129
type: Class

Ethyl mercury (C2H5Hg+)
notation: C2H5Hg
type: Class
subclass of: Mercury Species

Laboratory Result
type: Class
definition: A measurement taken on a sample.
subclass of: SampleIndicator

Screening
type: Class
subclass of: SIO_000417
was approved by: chear-kb:PER-Jeanette-Stingone
definition: The time period during which a screening process is used to determine the inclusion of a subject in a study.

nanogram
type: SIO_000074
notation: ng

Perfluorooctanesulfonic acid
definition: Perfluoroalkyls are stable, synthetic chemicals. Perfluoroalkyls are unique because they repel oil, grease, and water. The two perfluoroalkyls made in the largest amounts in the U. S. areperflurooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Perfluoroalkyls have been used in surface protection products such as carpet and clothing treatments and coating for paper and cardboard packaging. They have also been used in fire-fighting foams.
notation: PFOS
type: Class
subclass of: PFC

Tobacco Smoke Exposure
type: Class
notation: 98
type: QualityValue
subclass of: Environmental Exposure

dimethylphosphate
notation: DMP
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.

N-Acetyl-S- (3, 4-dihydroxybutyl)-L-cysteine
notation: DHBMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Plasma
definition: The liquid component of blood, in which erythrocytes are suspended. [database_cross_reference: http://orcid.org/0000-0002-6601-2165]
subclass of: Blood Component
type: Class

Immunoturbidimetry
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: SIO_001007
definition: An analytical technique that uses light scattering, a physical phenomenon resulting from the interaction of light with particles in solution, to measure the concentration of particles. The photometric signal is generated by a decrease in light intensity as a direct consequence of increasing turbidity in the reaction well. Immunoturbidimetry uses the classical antigen-antibody reaction. The antigen-antibody complexes are particles which can be optically detected by an photometer.

microampere
notation: µA
type: SIO_000074

Interlocutory Marital Status
subclass of: Marital Status
type: Class
definition: The condition existing when an order or judgement is considered temporary until either a specified period of time has passed or specific information is provided to assist in rendering a permanent decision.
notation: 44
type: QualityValue

Delivery Characteristics
subclass of: StudyIndicator
definition: Attributes related to the delivery of a child.
type: Class

N-Acetyl-S-(1-phenyl-2-hydroxyethyl-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine
notation: PHEMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Pregnancy Characteristic
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Pregnancy Characteristic Indicator Class
subclass of: StudyIndicator
type: Class

Education Grade 2
type: Class
definition: Finished grade 2
notation: 114
type: QualityValue
subclass of: Some Elementary School

Cyclomicrons present
type: Class
subclass of: SIO_001167

Malaria
subclass of: SIO_010299
subclass of: Medical History
type: Class
notation: 121
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
type: QualityValue

gigabasepair
notation: Gb
type: SIO_000074

Reverse-Phase Mass Spectrometry Profiling
subclass of: MassSpectrometry
type: Class

Phenylglyoxylic acid
subclass of: Volatile Organic Compound
notation: PGA
type: Class
editorial note: To Do: align with CHEBI.

9-hydroxyphenanthrene
subclass of: PAH
notation: PHEN9
type: Class

2, 3', 4, 4'-Tetrabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE66
type: Class
editorial note: To Do: align with CHEBI.

Student
notation: 66
subclass of: Occupation
type: QualityValue
type: Class

Uranium
notation: U
definition: Uranium. A radioactive element of the actinide series of metals. URANIUM has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.
subclass of: Metal
type: Class

6-chloronicotinic acid
notation: CINA6

2, 4'-DDT
type: Class
notation: OPDDT
subclass of: Organochlorine Compound

(7Z, 10Z, 13Z, 16Z, 19Z)-docosapentaenoic acid
definition: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.
subclass of: Fatty Acid
notation: C225N3
type: Class

1-hydroxypyrene
notation: PYR1
subclass of: PAH
type: Class

Intelligence Quotient
type: QuantityVariable
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000052
subclass of: Physical and Mental Assessment
type: Class
definition: A measure of intelligence

Unknown Race
definition: Unknown Race
type: QualityValue
subclass of: Race
type: Class
notation: 48

mass volume percentage
notation: (w/v)
type: SIO_000074

dimethyldithiophosphate
notation: DMDP
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.

African American
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Race
definition: A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American".
notation: 8
type: QualityValue
type: Class

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOCPHE

Mental Health
subclass of: Physical and Mental Assessment
type: Class
definition: Mental Health Indicator
was approved by: chear-kb:PER-Jeanette-Stingone

Perfluorooctanesulfonamide
subclass of: PFC
notation: PFOSA
type: Class

Education Grade 7
notation: 119
type: QualityValue
subclass of: Some Middle School
definition: Finished grade 7
type: Class

electronvolt
notation: eV
type: SIO_000074

Boiler Count
type: Class
subclass of: Household Appliance Count
type: QuantityVariable
definition: A boiler is an object that heats up water. This attribute quantifies the number of boilers in the home.
was approved by: chear-kb:PER-Jeanette-Stingone

Sample integrity/quality compromised preventing analysis
subclass of: SIO_001167
type: Class

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
subclass of: Inductively Coupled Plasma Mass Spectrometer
definition: A tandem mass spectrometer consisting of two quadrupole mass analyzers in series, with a (non-mass-resolving) radio frequency (RF)–only quadrupole between them to act as a cell for collision-induced dissociation.
type: Class
was approved by: chear-kb:PER-Jim-McCusker

Circumference
subclass of: Anthropometry
type: Class
type: QuantityVariable

Refractometer
definition: A laboratory or field device for the measurement of an index of refraction (refractometry). The index of refraction is calculated from Snell's law while for mixtures, the index of refraction can be calculated from the composition of the material using several mixing rules such as the Gladstone–Dale relation and Lorentz–Lorenz equation.
subclass of: PhysicalInstrument
type: Class
was approved by: chear-kb:PER-Jim-McCusker

Married
subclass of: Marital Status
definition: Indicates a person currently joined in a legally binding matrimonial union. Classify common law marriage as married. Includes married couples living together and not living together.
notation: 37
type: Class
type: QualityValue

Predominantly fibrous material
subclass of: SIO_001167
type: Class

degree Fahrenheit
type: SIO_000074
notation: F

Concentration
type: Class
subclass of: Laboratory Result
type: QuantityVariable

Weight
type: QuantityVariable
type: Class
subclass of: SIO_000279
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Anthropometry
definition: The resulting Force from the interaction between a person's Mass and Gravity.

Non-Spontaneous Preterm Birth
subclass of: Preterm Birth
type: QualityValue
notation: 60
type: Class

milligray
type: SIO_000074
notation: mGy

Platinum
definition: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) PLATINUM is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
type: Class
subclass of: Metal
notation: Pt

2-thoxothazlidne-4-carbxylic acid(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCTTC
type: Class
editorial note: To Do: align with CHEBI.

gamma-hexachlorocyclohexane
type: Class
notation: GHCH
subclass of: Organochlorine Compound

Feces
definition: Portion of semisolid bodily waste discharged through the anus[MW, modified] [database_cross_reference: http://en.wikipedia.org/wiki/Feces][database_cross_reference: http://www.merriam-webster.com/dictionary/feces]
type: Class
subclass of: Biospecimen

Sample older than 2 weeks
subclass of: SIO_001167
type: Class

(9Z)-hexadecenoic acid
definition: A hexadecenoic acid with a cis-double bond at position C-9.
subclass of: Fatty Acid
type: Class
notation: C161N7

candela
notation: cd
type: SIO_000074

Absorbance Reader
definition: Absorbance readers are used for assays such as ELISA assays, protein and nucleic acid quantification or enzyme activity assays. A light source illuminates the sample using a specific wavelength (selected by an optical filter, or a monochromator), and a light detector located on the other side of the well measures how much of the initial (100%) light is transmitted through the sample: the amount of transmitted light will typically be related to the concentration of the molecule of interest.
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: Microplate Reader

Ethylbenzene
notation: EB
subclass of: Volatile Organic Compound
definition: Ethylbenzene is mainly used in the manufacture of styrene. Acute (short-term) exposure to ethylbenzene in humans results in respiratory effects, such as throat irritation and chest constriction, irritation of the eyes, and neurological effects such as dizziness. Chronic (long-term) exposure to ethylbenzene by inhalation in humans has shown conflicting results regarding its effects on the blood. Animal studies have reported effects on the blood, liver, and kidneys from chronic inhalation exposure to ethylbenzene. Limited information is available on the carcinogenic effects of ethylbenzene in humans. In a study by the National Toxicology Program (NTP), exposure to ethylbenzene by inhalation resulted in an increased incidence of kidney and testicular tumors in rats, and lung and liver tumors in mice. EPA has classified ethylbenzene as a Group D, not classifiable as to human carcinogenicity.
type: Class

Perfluorohexane-1-sulphonic acid
notation: PFHxS
subclass of: PFC
type: Class

Spontaneous Caesarian Section
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 22
subclass of: Caesarian Section
type: QualityValue
definition: Had a spontaneous caesarian section

Environmental Phenol
type: Class
subclass of: Targeted Analyte

Object
type: Class
subclass of: ScienceIndicator

Medical History
subclass of: StudyIndicator
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Medical History Indicator Class

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
notation: HPMA
subclass of: Volatile Organic Compound

2, 2', 4, 4', 5-Pentabromodiphenyl ether
notation: BDE99
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether

Quadrapole Time-of-Flight Liquid Chromotography-Mass Spectrometry
subclass of: Liquid Chromotography-Mass Spectrometery
type: Class

Mitest not capped
subclass of: SIO_001167
type: Class

centimeter
type: SIO_000074
notation: cm

kilovolt-hour
type: SIO_000074
notation: kVh

Samples Arrived Thawed and Analyzed
type: Class
subclass of: SIO_001167

N-Acetyl-S-(benzyl)-L-cysteine(ng/mL)
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: VOCBMA
type: Class

cell in vitro
type: Class
subclass of: Cell

Landfill Proximity
definition: How close a household is to a landfill.
subclass of: SIO_000041
type: Class
subclass of: Environmental Exposure
was approved by: chear-kb:PER-Jeanette-Stingone
type: QuantityVariable

Behavioral Experimental Paradigm
type: Class
subclass of: Neurocognitive Assessment

Lymphocyte
subclass of: Leukocyte
definition: A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
type: Class

N-acetyl-S-(2-cyanoethyl)-L-cyst(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCCYM
type: Class
editorial note: To Do: align with CHEBI.

terabyte
type: SIO_000074
notation: TB

kilogram
type: SIO_000074
notation: kg

Mass Spectrometer
type: Class
definition: Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio. In simpler terms, a mass spectrum measures the masses within a sample. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures.
subclass of: PhysicalInstrument
was approved by: chear-kb:PER-Jim-McCusker

red blood cell count
subclass of: SIO_000794
type: Class

Cis-Nonachlor
subclass of: Organochlorine Compound
notation: CNON
type: Class

College Graduate
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Higher Education
type: QualityValue
definition: The quality of having graduated from College
notation: 12

Freeze/Thaw Cycles Count
subclass of: SIO_000794
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Number of Freeze/Thaw cycles.
type: QuantityVariable

experimentally modified cell in vitro
subclass of: Cell
type: Class

Birth Outcome
definition: Birth Outcomes Indicator Class
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator
editorial note: • [WARNING] SDD_00013: The Dictionary Mapping has the following cells with missing labels: cmo:0001297 .

Plutonium
notation: Pu
subclass of: Metal
type: Class
definition: Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.

Electrospray Ionization Mass Spectrometry
definition: Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.
was approved by: chear-kb:PER-Jim-McCusker
subclass of: MassSpectrometry
type: Class

mono-pentyl phthalate
notation: mPeP
subclass of: Phthalate
type: Class

Collection Date of Sample
definition: Collection Date of Sample
subclass of: SIO_000417
type: QuantityVariable
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class

microliter
notation: µl
type: SIO_000074

Nitrogen Oxide
type: Class
subclass of: Analyte

million parts per microgram
notation: x106 µL
type: SIO_000074

Tin
type: Class
notation: Sn
definition: TIN is a trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
subclass of: Metal

Native Hawaiian or Other Pacific Islander
type: Class
subclass of: Race
notation: 55
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityValue
definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands.

Before
type: Class
subclass of: Relative Time
definition: A negative index of a time measurement in relation to a reference event. A conventional time measurement can be generated from a before time measurement by duplicating the measurement, reversing the sign of the value, and removing the "Before" class.

Specimen analyzed with less than usual dilution
type: Class
subclass of: SIO_001167

femtomolar
type: SIO_000074
notation: fM

Preschool Child Behavior Checklist Internalizing Subscale
subclass of: Neurocognitive Assessment
type: Class
definition: Subscale of preschool CBCL that assesses internalizing behaviors

Bedroom Count
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Room Count
definition: Total Number of Bedrooms in the Home
type: QuantityVariable

4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol
type: Class
subclass of: Tobacco Metabolite
editorial note: To Do: align with CHEBI.
notation: NNAL

Hemolyzed (covers all three levels), lipemic, and icteric
type: Class
subclass of: SIO_001167

N-Acetyl-S-(trichlorovinyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
type: Class
notation: VOCTCV
subclass of: Volatile Organic Compound

Kaufman ABC
definition: culturally fair, cognitive ability test for children
type: Class
subclass of: Neurocognitive Assessment

SpectraMax Plus 384 Microplate Reader
was approved by: chear-kb:PER-Jim-McCusker
subclass of: Microplate Reader
type: Class
definition: Get absorbance measurements from 190 to 1000 nm quickly for samples in test tubes, cuvettes, and 96- or 384-well microplates. The SpectraMax® Plus 384 Microplate Reader gives you walk-up convenience for both standard spectrophotometer and microplate reader applications on the same instrument. Monochromator wavelength selection saves you the time and trouble of ever having to change out filters. Typical applications for this powerful reader include DNA and RNA quantification, enzyme kinetic assays, and ELISA based assays. When your project is ready for high throughput, take advantage of StakMax® automated microplate handling compatibility for full robotic integration.

hour
type: SIO_000074
notation: h

Behavior Rating Inventory of Executive Function – Preschool Version
definition: Standardized rating scale designed to specifically measure the range of executive function in preschool-aged children
subclass of: Neurocognitive Assessment
type: Class

millisievert
notation: mSv
type: SIO_000074

Stress
definition: Whether or not a person gets stressed.
type: QualityValue
notation: 92
subclass of: Stress Frequency
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

Beginning
subclass of: Restriction
  has value: 1
  on property: hasValue
type: Class
subclass of: Relative Time
definition: A time relative to the beginning of an event

Cotinine
type: Class
subclass of: Tobacco Metabolite
definition: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
notation: COT

Cyclohexane-1, 2-dicarboxylic acid mono carboxyisooctyl ester (DINCH)
notation: MCOCH

PCB101
type: Class
subclass of: Polychlorobiphenyl
notation: PCB101

minute
notation: min
type: SIO_000074

Fast Food Consumption
type: Class
definition: Whether or not fast food is consumed.
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Fast Food Consumption Frequency
notation: 16
type: QualityValue

Trans-Nonachlor
type: Class
notation: TNON
subclass of: Organochlorine Compound

Technical Post-Middle School
subclass of: High School or Less
notation: 94
type: Class
subclass of: Technical School
type: QualityValue
definition: Attended a Technical Post-Middle School.
was approved by: chear-kb:PER-Jeanette-Stingone

Abdomen
subclass of: SIO_010046
type: Class

Education Grade
subclass of: Education
type: QualityVariable
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: The highest grade of education achieved

gram per cubic centimeter
notation: g/cm3
type: SIO_000074

picovolt
type: SIO_000074
notation: pV

Prenatal Smoker
notation: 77
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
type: QualityValue
definition: The quality of having smoked while being pregnant.
type: Class
subclass of: Smoker

mebibyte
type: SIO_000074
notation: MiB

Tandem Mass Spectrometer
definition: Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages. In a tandem mass spectrometer, ions are formed in the ion source and separated by mass-to-charge ratio in the first stage of mass spectrometry (MS1). Ions of a particular mass-to-charge ratio (precursor ions) are selected and fragment ions (product ions) are created by collision-induced dissociation, ion-molecule reaction, photodissociation, or other process. The resulting ions are then separated and detected in a second stage of mass spectrometry (MS2).
subclass of: Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class

becquerel
notation: Bq
type: SIO_000074

Education
subclass of: SIO_000026
subclass of: Demographic
subclass of: Socioeconomic Status
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: The act or process of imparting or acquiring knowledge.
type: QualityVariable

Adopted
type: Class
definition: Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents, and, in so doing, permanently transfers all rights and responsibilities, along with filiation, from the biological parent or parents.
subclass of: Non-Biological Relative

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: GAMA
subclass of: Volatile Organic Compound
type: Class

2-amnothiazolne-4-carbxylic acid(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCATC
type: Class
editorial note: To Do: align with CHEBI.

Pentachlorophenol
definition: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
notation: PCP
subclass of: Environmental Phenol
type: Class

diethylthiophosphate
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
notation: DETP

Icteric
type: Class
subclass of: SIO_001167

Total nicotine
editorial note: Duplicate of NIC?
notation: TNIC
type: Class
subclass of: Tobacco Metabolite

Nornicotine
notation: NORN
type: Class
subclass of: Tobacco Metabolite

Never Married
type: QualityValue
definition: Indicates a person who has never been married or whose marriages have been annulled.
type: Class
subclass of: Unmarried
notation: 38

skin fold thickness, suprailiac
subclass of: SampleIndicator
type: Class

Computer
subclass of: Household Appliance Count
type: QuantityVariable
definition: A machine used for computation and much more.
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

meter
type: SIO_000074
notation: m

count per nanomolar second
type: SIO_000074
notation: 1/nMs

Lymphotoxin-alpha
subclass of: SIO_010043
notation: TNFB
type: Class

Heptyl paraben
notation: HePB
subclass of: Paraben
type: Class

kilovolt
type: SIO_000074
notation: kV

Canned Food Consumption
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 9
definition: Whether or not canned food is consumed.
subclass of: Canned Food Consumption Frequency
type: QualityValue

Leukocyte
subclass of: Blood Component
definition: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
type: Class

Language
type: QualityVariable
subclass of: Acculturation
type: Class
editorial note: Needs to be rooted in sio

Lipemic
subclass of: SIO_001167
type: Class

pascal
notation: Pa
type: SIO_000074

nanoliter
notation: nl
type: SIO_000074

Specific Gravity
type: QuantityVariable
subclass of: SIO_001018
editorial note: Why is this here? Maybe it belongs in another list
type: Class
subclass of: SampleIndicator
definition: Specific gravity is the ratio of the density of a substance to the density of a reference substance; equivalently, it is the ratio of the mass of a substance to the mass of a reference substance for the same given volume. Apparent specific gravity is the ratio of the weight of a volume of the substance to the weight of an equal volume of the reference substance. The reference substance is nearly always water at its densest (4°C) for liquids; for gases it is air at room temperature (21°C). Nonetheless, the temperature and pressure must be specified for both the sample and the reference. Pressure is nearly always 1 atm (101.325 kPa). Temperatures for both sample and reference vary from industry to industry.

High Performance Liquid Chromatography
subclass of: Chromatography
type: Class

2-Methylhippuric acid (ng/mL)
type: Class
notation: VOC2MH
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

micromolal
notation: µmol/kg
type: SIO_000074

Socioeconomic Status
type: Class
definition: Socioeconomic Status Indicator Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator

Overweight
subclass of: Body Weight Quality
type: QualityValue
notation: 71
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
type: Class

Insulin
type: Class
subclass of: Analyte
subclass of: Biological Response
definition: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes.
subclass of: SIO_010043

Parous
subclass of: Parity
type: QualityValue
notation: 73
type: Class

trans, trans -Muconic acid
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: MU
type: Class

unit per milliliter
type: SIO_000074
notation: U/ml

Cold Vapor Atomic Fluorescence Spectroscopy Instrument
definition: Used in the measurement of trace amounts of volatile heavy metals such as mercury, cold vapour AFS makes use of the unique characteristic of mercury that allows vapour measurement at room temperature.
subclass of: Atomic Fluorescence Spectroscopy Instrument
type: Class
was approved by: chear-kb:PER-Jim-McCusker

Household Income
subclass of: Socioeconomic Status
type: Class
type: QuantityVariable
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000052
definition: A demographic parameter indicating the amount of earnings made by a family.

count per molar
notation: 1/M
type: SIO_000074

nanograms per liter
type: SIO_000074
notation: ng/L

diethylphosphate
type: Class
notation: DEP
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.

Toaster Count
type: QuantityVariable
subclass of: Household Appliance Count
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class
definition: Number of appliances used to toast bread.

Leptin
subclass of: Biological Response
subclass of: SIO_010043
definition: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.
type: Class
subclass of: Analyte

Household
subclass of: SIO_001064
type: Class
subclass of: Housing Characteristic
definition: A household consists of one or more people who live in the same dwelling and also share meals or living accommodation, and may consist of a single family or some other grouping of people. A single dwelling will be considered to contain multiple households if either meals or living space are not shared. The household is the basic unit of analysis in many social, microeconomic and government models, and is important to the fields of economics and inheritance.

Common Era
subclass of: Relative Time
type: Class
definition: Common era time measurements are referenced against (in relation to) the beginning of the common era, 1 CE (or 1 AD).
equivalent class: Restriction
  has value: First Year of the Common Era
  on property: inRelationTo

cyclic peptide
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
type: Class
subclass of: Analyte

No Formal Education
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 57
type: QualityValue
subclass of: Education
type: Class
definition: Has not been educated in a formal setting.

Hospitalization
notation: 104
type: QualityValue
subclass of: Hospital Utilization
subclass of: SIO_001024
type: Class
definition: Admission to a hospital

Birth Cohort Study
subclass of: CohortStudy
type: Class

Relative
definition: Broadly, kinship patterns may be considered to include people related by both descent – i.e. social relations during development – and by marriage. Human kinship relations through marriage are commonly called "affinity" in contrast to the relationships that arise in one's group of origin, which may be called one's descent group. In some cultures, kinship relationships may be considered to extend out to people an individual has economic or political relationships with, or other forms of social connections. Within a culture, some descent groups may be considered to lead back to gods or animal ancestors (totems). This may be conceived of on a more or less literal basis.
subclass of: SIO_000016
subclass of: Demographic
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Relative
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

Hospital Readmissions
subclass of: Hospital Utilization
definition: An episode when a patient who had been discharged from a hospital is admitted again within a specified time interval.
subclass of: SIO_000794
type: Class

Medication
subclass of: Prescription Medication and Dietary Supplements
type: QualityVariable
type: Class
notation: 142
definition: A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product.

Car Count
type: Class
subclass of: Housing Characteristic
editorial note: Again, this isn't related to physical properties of housing. This is more closely related to Socioeconomic Status. Consider moving it.
definition: Total Number of Cars in the Home
type: QuantityVariable
subclass of: SIO_000794

Initial concentration higher than the highest standard, insufficient volume for repeat analysis (93, 18)
subclass of: SIO_001167
type: Class

Exposure Monitoring Instrument
type: Class
definition: A physical instrument that monitors the environment for chemical exposures.
subclass of: PhysicalInstrument
was approved by: chear-kb:PER-Jim-McCusker

Overloaded filter
subclass of: SIO_001167
type: Class

Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: Ultra Performance Liquid Chromatography - Mass Spectrometer
subclass of: Tandem Mass Spectrometer

Inductively Coupled Plasma Mass Spectrometer
subclass of: Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class
definition: A type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 10^15 (part per quadrillion, ppq) on non-interfered low-background isotopes. This is achieved by ionizing the sample with inductively coupled plasma and then using a mass spectrometer to separate and quantify those ions.

Nail
type: Class
subclass of: Tissue
definition: A nail that is part of a manual digit. [database_cross_reference: OBOL:automatic]

N-Ac-S-(2-Hydrxy-3-butnyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Volatile Organic Compound
notation: VOCMB2

N-Acetyl-S-(benzyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: BMA

Fever
type: QualityValue
definition: Elevated body temperature due to failed thermoregulation.
type: Class
notation: 123
subclass of: Phenotype

N-Acetyl-S-(2-cyanoethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
type: Class
notation: CYMA
subclass of: Volatile Organic Compound

mono-isononyl phthalate
notation: mINP
subclass of: Phthalate
type: Class

Magnesium
definition: An element with atomic symbol Mg, atomic number 12, and atomic weight 24.3. Magnesium is an alkaline earth metal and is important to bone structure in human physiology.
subclass of: Metal
type: Class
notation: Mg

Lithium
type: Class
definition: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
notation: Li
subclass of: Metal

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
subclass of: Environmental Phenol
notation: PHEN2_PHEN3
type: Class

gram per mole
notation: g/mol
type: SIO_000074

cells per milliliter
notation: cells per ml
type: SIO_000074

Interleukin-17F
notation: IL17F
subclass of: SIO_010043
type: Class

Childhood Period
subclass of: SIO_000417
type: Class
definition: The age span ranging from birth to adolescence
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000582
subclass of: From Birth

cubic centimeter
notation: cm3
type: SIO_000074

Mono-2-ethyl-5-oxohexylterephthalate
notation: MEOHTP

Childhood
definition: A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence.
type: Class
subclass of: Developmental Quality
type: QualityValue
notation: 11
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Demographic

Matrix metalloproteinase-9
type: Class
notation: MMP9
subclass of: SIO_010043

Perfume Use
subclass of: Personal Product Use
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 74
type: QualityValue

Monocyclohexyl phthalate
subclass of: Phthalate
notation: MCHP
type: Class

thousand parts per microgram
notation: x103 µL
type: SIO_000074

2-Thioxothiazolidine-4-carboxylic acid
notation: TTCA
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class

(15Z)-tetracosenoic acid
type: Class
notation: C241N9
subclass of: Fatty Acid
definition: A tetracosenoic acid having a cis-double bond at position 15.

Monoisopropyl phthalate
subclass of: Phthalate
type: Class
notation: MiPP

Preschool Child Behavior Checklist Externalizing Subscale
definition: Subscale of preschool CBCL that assesses externalizing behaviors
type: Class
subclass of: Neurocognitive Assessment

Soil Floor
definition: The flooring is made of soil.
notation: 84
subclass of: Floor Type
type: QualityValue
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

No preservative added
subclass of: SIO_001167
type: Class

Vanadium
notation: V
definition: A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.
subclass of: Metal
type: Class

deciliter
notation: dl
type: SIO_000074

cubic centimeter per mole
type: SIO_000074
notation: cm3/mol

4-hydroxychrysene
type: Class
notation: CHRY4
subclass of: PAH

Hospital Utilization
type: Class
subclass of: Healthcare Access
definition: Hospital Utilization
was approved by: chear-kb:PER-Jeanette-Stingone

Small Molecule
subclass of: Biomolecule
definition: A small molecule is a low molecular weight (< 900 daltons) organic compound that may help regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
type: Class

cells per microliter
notation: cp/µl
type: SIO_000074

Never Smoked
type: QualityValue
definition: The quality of never smoking in the past.
notation: 56
type: Class
subclass of: Smoking Status
was approved by: chear-kb:PER-Jeanette-Stingone

Forceps-Assisted Birth
definition: A vaginal birth with the assistance of forceps to extract the baby.
type: Class
notation: 25
type: QualityValue
subclass of: Vaginal Birth

3, 4-Dihydroxy benzoic acid
subclass of: Environmental Phenol
type: Class
notation: DHB34

N-Acetyl-S-(phenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
type: Class
notation: PMA
subclass of: Volatile Organic Compound

Interleukin-25
subclass of: SIO_010043
notation: IL17EIL25
type: Class

tetracosanoic acid
subclass of: Fatty Acid
notation: C240
type: Class
definition: A C24 straight-chain saturated fatty acid.

kilobasepair
notation: kbp
type: SIO_000074

Patella
subclass of: SIO_010046
type: Class
definition: The patella, also known as the knee cap or kneepan, is the largest sesamoid bone in the human body. The primary functional role of the patella is knee extension. The patella has convergently evolved in placental mammals and birds; marsupials have only rudimentary, non-ossified patellae. In more primitive tetrapods, including living amphibians and reptiles, the muscle tendons from the upper leg are attached directly to the tibia, and the patella is not present. See also: fabella.

Liquid Chromotography-Multistage Mass Spectrometery
subclass of: MassSpectrometry
type: Class

Fms-related tyrosine kinase 3 ligand
subclass of: SIO_010043
type: Class
notation: FLT3L

Child
subclass of: Descendant
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      all values from: Parent
      on property: hasRole
    intersection of: SIO_000485
definition: A relationship with a parent (such as sons and daughters of any age).
type: Class

Tibia
definition: The major preaxial endochondral bone in the posterior zeugopod.
subclass of: SIO_010046
type: Class

Oxybenzone
subclass of: Volatile Organic Compound
type: Class
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
notation: OXB

Chromatography Instrument
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: PhysicalInstrument
definition: Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.

SIO_001068
notation: 135
type: QualityValue

Head
subclass of: SIO_010046
type: Class

Parental Health and Family History
definition: Parental Health and Family History Indicator Class
type: Class
subclass of: StudyIndicator
was approved by: chear-kb:PER-Jeanette-Stingone

No FOL result; FOL = 8 ng/mL assumed
subclass of: SIO_001167
type: Class

parts per trillion
notation: ppt
type: SIO_000074

hertz
type: SIO_000074
notation: Hz

Obese
type: QualityValue
notation: 63
subclass of: Body Weight Quality
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
type: Class

white blood cell count
type: Class
subclass of: SIO_000794

Tungsten
notation: W
type: Class
definition: Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. TUNGSTEN is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.
subclass of: Metal

native cell
type: Class
subclass of: Cell

Z-Score
type: Class
subclass of: Anthropometry
definition: A z-score (also known as z-value, standard score, or normal score) is a measure of the divergence of an individual experimental result from the most probable result, the mean. Z is expressed in terms of the number of standard deviations from the mean value.

Arsenic (V) Acid
notation: Arsenic (V) Acid
type: Class
subclass of: Arsenic Species

A Sample has a Pairing
subclass of: SIO_001049
type: Class
definition: Refers to having paired samples.
editorial note: This actually should be a process. What should we do?
was approved by: chear-kb:PER-Jeanette-Stingone

8-isoprostane
subclass of: Biological Response
type: Class
subclass of: Biomolecule

N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
notation: MHBMA1
editorial note: To Do: align with CHEBI.

Pregnancy
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
subclass of: Pregnancy Characteristic
definition: The time during which one or more offspring develops inside a woman.
subclass of: SIO_000417
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: From Conception

colony forming unit per milliliter
notation: cfu/ml
type: SIO_000074

cis-4, 10, 13, 16-docosatetraenoic acid
type: Class
notation: C224N6
subclass of: Fatty Acid

Attribute
type: Class
subclass of: ScienceIndicator

Monocyte
subclass of: Lymphocyte
definition: Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.
type: Class

Triclocarban
type: Class
notation: TCC
definition: Triclocarban is a triclosan analogue with an antibacterial property. Triclocarban exerts its effect by inhibiting the activity of enoyl-(acyl-carrier protein) (ACP) reductase, widely distributed in bacteria, fungi and plants. ACP reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. As a result, this agent interrupts cell membrane synthesis and leads to bacterial growth inhibition.
subclass of: Environmental Phenol

Preschool
type: Class
notation: 112
subclass of: Education Grade
type: QualityValue
definition: Finished preschool

Propyl paraben
subclass of: Paraben
definition: Propylparaben is a Standardized Chemical Allergen. The physiologic effect of propylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of propylparaben is Allergens.
notation: PrPB
type: Class

Nicotine-N-oxide
subclass of: Tobacco Metabolite
notation: NICO
type: Class

Seizures
subclass of: Phenotype
type: Class
definition: Seizures are an intermittent abnormality of the central nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures.
notation: 125
type: QualityValue

Homemaker
type: QualityValue
notation: 68
subclass of: Occupation
type: Class
definition: A person who manages a home as their main daily activity.

Other Material Finish
definition: Flooring is made from another unspecified material.
subclass of: Floor Type
type: Class
notation: 70
type: QualityValue
was approved by: chear-kb:PER-Jeanette-Stingone

Interleukin-27 subunit alpha
type: Class
notation: IL27
subclass of: SIO_010043

Lead
notation: Pb
subclass of: Metal
type: Class
definition: LEAD is a soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.19, symbol Pb. (Dorland, 28th)

disintegrations per second
notation: dps
type: SIO_000074

Private Insurance or Self Pay
subclass of: Insurance
type: QualityValue
notation: 51
type: Class

volt-hour
type: SIO_000074
notation: Vh

all-cis-docosa-4, 7, 10, 13, 16, 19-hexaenoic acid
definition: A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
subclass of: Fatty Acid
type: Class
notation: C226N3

Molybdenum
notation: Mo
definition: MOLYBDENUM is a metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)
type: Class
subclass of: Metal

Liquid Chromotography -tandem mass spectrometry
subclass of: MassSpectrometry
type: Class

N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
notation: MHBMA3
subclass of: Volatile Organic Compound

Bathroom Count
subclass of: Room Count
type: QuantityVariable
type: Class
definition: Total Number of Bathrooms in the Home
was approved by: chear-kb:PER-Jeanette-Stingone

watt per steradian
notation: W/sr
type: SIO_000074

tetradecanoic acid
notation: C140
subclass of: Fatty Acid
definition: A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
type: Class

3-hydroxyphenanthrene
notation: PHEN3
type: Class
subclass of: PAH

picogram
notation: pg
type: SIO_000074

Aligent 8800 Triple Quadrupole ICP-MS
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer

thawed, hemolyzed (covers all three levels) and exposed to light
subclass of: SIO_001167
type: Class

Arsenous ( III) Acid
notation: Arsenous (III) Acid
subclass of: Arsenic Species
type: Class

2, 5-Dichlorophenol
subclass of: Environmental Phenol
type: Class
definition: PHYSICAL DESCRIPTION: Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 µg/L at 68-72°F; 33 µg/L at 86°F. Taste threshold 0.5 µg/L. (NTP, 1992)
notation: DCP25

Graduated From High School
definition: The quality of having graduated from High School
type: QualityValue
notation: 32
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: High School or Less
type: Class

Histidine-rich protein PFHRP-II
subclass of: SIO_010043
type: Class

Father
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Parent
type: Class
definition: The male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental legal and social relationship with the child that carries with it certain rights and obligations. An adoptive father is a male who has become the child's parent through the legal process of adoption. A biological father is the male genetic contributor to the creation of the baby, through sexual intercourse or sperm donation. A biological father may have legal obligations to a child not raised by him, such as an obligation of monetary support. A putative father is a man whose biological relationship to a child is alleged but has not been established. A stepfather is a male who is the husband of a child's mother and they may form a family unit, but who generally does not have the legal rights and responsibilities of a parent in relation to the child.
subclass of: Restriction
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010048
  on property: isRoleOf

Very turbid
subclass of: SIO_001167
type: Class

Teenager
type: Class
subclass of: Developmental Quality
notation: 137
type: QualityValue
definition: An individual between the ages of 13 and 19.
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Demographic

Torn, perforated screen
subclass of: SIO_001167
type: Class

mono ethyl hexyl phthalate
notation: MEHP
type: Class
definition: PHYSICAL DESCRIPTION: Clear colorless to cloudy white viscous liquid. (NTP, 1992)
subclass of: Phthalate

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine
subclass of: Volatile Organic Compound
notation: HEMA2
type: Class

newton
type: SIO_000074
notation: Ntn

N-Acetyl-S- (2-carboxyethyl)-L-cysteine
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: CEMA
type: Class

2-Chlorophenol
definition: 2-chlorophenol is a colorless to amber liquid with an unpleasant, penetrating odor. Density 1.265 g / cm3. Sinks in water and slowly dissolves. Freezing point 7°C (46°F). Boiling point 175°C (347°F).
type: Class
notation: MCP2
subclass of: Environmental Phenol

Cement Floor
type: QualityValue
notation: 10
definition: Cement Floor Type
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Floor Type
type: Class

nanomolar
type: SIO_000074
notation: nM

High-Performance Liquid Chromatography
subclass of: Liquid Chromatography Instrument
was approved by: chear-kb:PER-Jim-McCusker
type: Class
definition: High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.

2-hydroxynaphthalene
type: Class
subclass of: PAH
notation: NAP2

Benzo[a]pyrene tetraol
type: Class
subclass of: PAH
notation: BAPT

Unmarried
definition: Indicates a person not currently joined in a legally binding matrimonial union.
type: QualityValue
subclass of: Marital Status
type: Class
notation: 46

Conception
subclass of: From Conception
type: Class
subclass of: SIO_000417
definition: When a sperm fertilizes an egg
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
subclass of: Beginning
was approved by: chear-kb:PER-Jeanette-Stingone

4, 4′-(1, 4-Phenylenediisopropylidene)bisphenol
notation: BPP

Nervous System
type: Class
subclass of: SIO_010003
definition: The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior

Fresh Vegetable Consumption
type: QualityValue
subclass of: Fresh Vegetable Consumption Frequency
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 29
type: Class
definition: Whether or not Fresh Vegetables are consumed.

Haircare Product Use
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Personal Product Use
notation: 30
type: QualityValue
type: Class

Housing Characteristic
type: Class
subclass of: StudyIndicator
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Housing Characteristic Indicator Class

blood lymphocyte count
subclass of: SIO_000794
type: Class

Lab confirmed result
type: Class
subclass of: SIO_001167

plaque forming unit
type: SIO_000074
notation: pfu

Preschool Child Behavior Checklist
type: Class
subclass of: Neurocognitive Assessment
definition: Child Behavior Checklist for ages 1 ½ through 5

Anemia
subclass of: Phenotype
notation: 128
type: QualityValue
type: Class
definition: A reduction in erythrocytes volume or hemoglobin concentration.

molar
notation: M
type: SIO_000074

parts per billion
notation: ppb
type: SIO_000074

Pre-Pregnancy
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000417
definition: The time before a pregnancy.
subclass of: From Conception
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
type: Class

Unusual color
type: Class
subclass of: SIO_001167

Cadmium
type: Class
notation: Cd
definition: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.
subclass of: Metal

Microwave Oven Count
definition: Number of machines in the home used to heat up food using microwaves.
type: QuantityVariable
subclass of: Household Appliance Count
editorial note: Putting a note here, but it applies to all of the appliances. These are used to calculate the SES Index that was reported within one of the pilots. So, there needs to be some connection between these terms.
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

Turbid
type: Class
subclass of: SIO_001167

neural cell
subclass of: Cell
type: Class

centiMorgan
type: SIO_000074
notation: cM

Separated
definition: Indicates a person living apart from his/her spouse by legal arrangement.
type: Class
subclass of: Married
notation: 41
type: QualityValue

systolic blood pressure
type: Class
subclass of: SampleIndicator

HPLC with Fluorescence Level Detector
subclass of: High-Performance Liquid Chromatography
type: Class
definition: HPLC paired with a Fluorescence Level Detector. Fluorescence spectroscopy (also known as fluorometry or spectrofluorometry) is a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light. A complementary technique is absorption spectroscopy. In the special case of single molecule fluorescence spectroscopy, intensity fluctuations from the emitted light are measured from either single fluorophores, or pairs of fluorophores.

Microarray Assay
subclass of: SIO_001007
type: Class
definition: An assay that uses a microarray to perform measurements.

millimole per liter
notation: mmol/L
type: SIO_000074

curie per liter
notation: curie/l
type: SIO_000074

Meconium
type: Class
subclass of: Pregnancy Sample
subclass of: Feces
definition: A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth. [database_cross_reference: BTO:0000838]

4, 4'-(1-phenylethylidene)bisphenol
notation: BPAP

Chromium
type: Class
notation: Cr
definition: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002, 1985), chromium and some of its compounds have been listed as known carcinogens.
subclass of: Metal

Selenium
notation: Se
definition: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
type: Class
subclass of: Metal

Quit Smoking
definition: Quit Smoking Cigarettes
type: Class
notation: 82
subclass of: Previous Smoker
type: QualityValue

4, 4'-DDT
notation: PPDDT
type: Class
subclass of: Organochlorine Compound

Result repeated and confirmed
subclass of: SIO_001167
type: Class

Hemolyzed (covers all three levels) and lipemic
type: Class
subclass of: SIO_001167

Foster
subclass of: Non-Biological Relative
definition: Fosterage, the practice of a family bringing up a child not their own, differs from adoption in that the child's parents, not the foster-parents, remain the acknowledged parents. In many modern western societies foster care can be organized by the state to care for children with troubled family backgrounds, usually on a temporary basis. In many pre-modern societies fosterage was a form of patronage, whereby influential families cemented political relationships by bringing up each other's children, similar to arranged marriages, also based on dynastic or alliance calculations.
type: Class

millimolal
type: SIO_000074
notation: mmol/kg

all-cis-5, 8, 11, 14, 17-icosapentaenoic acid
definition: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.
subclass of: Fatty Acid
notation: C205N3
type: Class

Spontaneous Preterm Birth
type: QualityValue
notation: 91
subclass of: Preterm Birth
type: Class

RNA Sequencing
subclass of: Nucleic Acid Sequencing
type: Class

picomoles per milliliter
type: SIO_000074
notation: pmol/ml

Polymerase Chain Reaction
type: Class
subclass of: SIO_001007

Demographic
definition: Demographics are quantifiable characteristics of a given population.
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
editorial note: SDD-2016-1431-P01_SG_Dictionary_SDD_v1.xlsx
subclass of: StudyIndicator

turns per second
type: SIO_000074
notation: 1/s

Oral Health
type: Class
definition: Oral Health Indicator Class
subclass of: StudyIndicator
was approved by: chear-kb:PER-Jeanette-Stingone

Broken Mitest
subclass of: SIO_001167
type: Class

Cotinine (total)
notation: COTT
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Tobacco Metabolite

Valid measurement, results repeated and confirmed (0, 33)
subclass of: SIO_001167
type: Class

High School or Less
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Education Level of High School or Less
type: QualityValue
notation: 33
subclass of: Education
type: Class

valid measurement
type: Class
subclass of: SIO_001167

Tooth
definition: Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Tooth_(animal)]
type: Class
subclass of: Tissue

meter per second
type: SIO_000074
notation: m/s

Surface-Induced Dissociation (SID)
subclass of: TandemMassSpectrometry
type: Class

Gadolinium
definition: Gadolinium. An element of the rare earth family of metals. GADOLINIUM has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
subclass of: Metal
type: Class
notation: Gd

candela per square meter
notation: cd/m2
type: SIO_000074

Conceiving
comment: to become pregnant with a child.
subclass of: SIO_000587
type: Class

parasite count
type: Class
subclass of: Concentration

Caesarian Section
subclass of: Pregnancy Characteristic
notation: 20
type: Class
subclass of: Route Of Delivery
definition: Caesarian Section Medical Procedure. One-third of pregnancies in the US end in C-Sections.
type: QualityValue

Underweight
type: QualityValue
subclass of: Body Weight Quality
notation: 99
type: Class
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
subclass of: Underweight/Normal
definition: BMI < 18.5

2, 4-Dichlorophenol
definition: 2, 4-dichlorophenol is a colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
notation: DCP24
subclass of: Environmental Phenol
type: Class

linoleic acid
notation: C182N6
definition: An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.
subclass of: Fatty Acid
type: Class

Interleukin-13
subclass of: SIO_010043
type: Class
notation: IL13

mono-isodecyl phthalate
type: Class
notation: mIDP
subclass of: Phthalate

Hexachlorobenzene
notation: HCB
type: Class
subclass of: Organochlorine Compound

Gray
notation: Gy
type: SIO_000074

Interleukin-1 beta
subclass of: SIO_010043
type: Class
subclass of: Biological Response
definition: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
notation: IL1B

microgram per liter
type: SIO_000074
notation: µg/L

steradian
type: SIO_000074
notation: sr

Cesium
subclass of: Metal
definition: A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.
notation: Cs
type: Class

Antimony
type: Class
notation: Sb
definition: ANTIMONY is a metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.
subclass of: Metal

cubic decimeter
notation: dm3
type: SIO_000074

White
type: Class
subclass of: Race
was approved by: chear-kb:PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
type: QualityValue
notation: 102

disintegrations per minute
notation: dpm
type: SIO_000074

percent
type: SIO_000074
notation: %

Interferon lambda-2
subclass of: SIO_010043
type: Class
notation: IL28A

1, 2-Dichloroethane
definition: Ethylene Dichloride is a clear, colorless, oily, synthetic, flammable liquid chlorinated hydrocarbon with a pleasant chloroform-like smell that emits toxic fumes of hydrochloric acid when heated to decomposition. Ethylene dichloride is primarily used to produce vinyl chloride. Inhalation exposure to this substance induces respiratory distress, nausea and vomiting and affects the central nervous system, liver and kidneys. It is mutagenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05)
notation: DE12
subclass of: Volatile Organic Compound
type: Class

Technical Post Primary School
type: QualityValue
subclass of: High School or Less
subclass of: Technical School
notation: 95
definition: Attended a Technical Post Primary School
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

pixels per inch
notation: p/in
type: SIO_000074

Technical Post Junior College
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Education
subclass of: Technical School
type: QualityValue
notation: 93
definition: Attended a Technical Post Junior College

Coma
type: Class
definition: Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli.
notation: 124
subclass of: Phenotype
type: QualityValue

Perfluorononanoic acid
subclass of: PFC
notation: PFNA
type: Class

Body Weight Quality
subclass of: Anthropometry
subclass of: SIO_000005
definition: A categorization of body mass relative to the height, as defined using Body Mass Index.
type: Class

SIO_010059
type: QualityValue
notation: 132

mono-carboxy isononyl phthalate
subclass of: Phthalate
type: Class
notation: mCINP

Metal
definition: For environmental purposes, CHEAR metals are metals and metalliods.
subclass of: Element
type: Class

Preterm Birth
definition: Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.
notation: 88
type: Class
subclass of: Birth Outcome
was approved by: chear-kb:PER-Jim-McCusker
type: QualityValue

Quit Smoking After Pregnancy
type: Class
subclass of: Prenatal Smoker
subclass of: Quit Smoking
definition: Quit Smoking After Pregnancy
subclass of: Pregnancy Characteristic
notation: 80
type: QualityValue

enzyme-linked immunosorbent assay (ELISA)
subclass of: Immunoassay
definition: ELISA is an immunoassay that uses antibodies and color change to identify a substance (Wikipedia)
type: Class

N-acel-S-(1, 2-dichlorovinl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOC1DC
type: Class

mono-isobutyl phthalate (DiBP)
type: Class
notation: MiBP
subclass of: Phthalate

DNA
subclass of: Macromolecule
type: Class

Barium
definition: BARIUM is an element of the alkaline earth group of metals. It has an atomic symbol Ba, atomic number 56, and atomic weight 138. All of its acid-soluble salts are poisonous.
type: Class
subclass of: Metal
notation: Ba

N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
subclass of: Volatile Organic Compound
notation: MHBMA2
type: Class
editorial note: To Do: align with CHEBI.

Unknown Education Level
notation: 101
type: Class
definition: Level of Education is not known
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityValue
subclass of: Education

Asian
subclass of: Race
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.
type: Class
notation: 6
was approved by: chear-kb:PER-Jeanette-Stingone

Hemoglobin
was approved by: chear-kb:PER-Jim-McCusker
type: Class
definition: The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae), as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism.
subclass of: SIO_010043

Annulled
type: QualityValue
definition: A marital status in which a voidable marriage is legally declared null and void, as though it never existed. Specific grounds for annullment vary within the presiding jurisdiction, whether geographic or religious.
notation: 43
type: Class
subclass of: Never Married

Run out-of-contol; insufficient sample for repeat analysis
type: Class
subclass of: SIO_001167

nanomolal
type: SIO_000074
notation: nmolal

kilodalton
type: SIO_000074
notation: kDa

American Indian Or AlaskanNative
subclass of: Race
type: Class
definition: A person having origins in any of the original peoples of North and South America (including Central America) and who maintains tribal affiliation or community attachment.
notation: 5
type: QualityValue
was approved by: chear-kb:PER-Jeanette-Stingone

Slightly hemolyzed
subclass of: SIO_001167
type: Class

kilogram per liter
notation: kg/L
type: SIO_000074

2, 4, 6-Trichlorophenol
subclass of: Environmental Phenol
notation: TCP246
type: Class
definition: 2 4 6-Trichlorophenol is a synthetic, colorless crystalline solid that is slightly soluble in water and soluble in organic solvents. It has been used primarily in pesticide formulations and as a wood preservative, although most uses have been cancelled in the US. When heated to decomposition, 2, 4, 6-trichlorophenol emits toxic and corrosive fumes of hydrochloric acid and other toxic gases. Exposure of humans to 2, 4, 6-trichrophenol via inhalation has been reported to cause respiratory effects, altered pulmonary function and pulmonary lesions. It is reasonably anticipated to be a human carcinogen. (NCI05)

micromole
notation: µmol
type: SIO_000074

Light Bulb Count
type: QuantityVariable
definition: Total Number of Lightbulbs in the Home
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Housing Characteristic
subclass of: SIO_000794
type: Class

Date of Birth
definition: Date of day on which a person was born.
type: QuantityVariable
subclass of: Demographic
subclass of: SIO_000417
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class

mono-methyl phthalate
subclass of: Phthalate
type: Class
notation: mMP

N-Ace-S-(3-Hydroxypropyl)-L-Cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCHPM

1-hydroxyphenanthrene
type: Class
subclass of: PAH
notation: PHEN1

micrometer
notation: µm
type: SIO_000074

dehydroepiandrosterone sulfate
type: Class
subclass of: Analyte
definition: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.

Physical Activity and Fitness
definition: Physical Activity and Fitness Indicator Class
subclass of: StudyIndicator
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class

normal
type: SIO_000074
notation: Norm

Interleukin-8
notation: IL8

did not precipitate
subclass of: SIO_001167
type: Class

milliampere
notation: mA
type: SIO_000074

Toluene
type: Class
notation: TOL
definition: Toluene is a widely used industrial solvent.
subclass of: Volatile Organic Compound

Religion
definition: Religious Belief
type: QualityVariable
type: Class
subclass of: Demographic

Trunk
definition: Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present.
type: Class
subclass of: SIO_010046

nanovolt
notation: nV
type: SIO_000074

area density unit
type: SIO_000074
notation: adu

curie
type: SIO_000074
notation: Ci

N-Acetyl-S-(n-propyl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
notation: BPMA
editorial note: To Do: align with CHEBI.

2, 2', 3, 4, 4', 5', 6-Heptabromodiphenyl ether
editorial note: To Do: align with CHEBI.
type: Class
notation: BDE183
subclass of: Polybrominated Diphenyl Ether

Nicotine
notation: NIC
definition: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
type: Class
subclass of: Tobacco Metabolite

Nickel
subclass of: Metal
type: Class
notation: Ni
definition: NICKEL is a trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.

mono (2-ethyl-5-oxohexyl) phthalate
notation: MEOHP
subclass of: Phthalate
type: Class

Phenylglyoxylic acid(ng/mL)
notation: VOCPHG
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

eosinophilic esophagitis in remission
type: Class
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of less than 15 eosinophils per high-power field area, or 0.158 mm^2 (400x).
equivalent class: Restriction
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
  on property: isPhenotypeOf

Fresh Vegetable Consumption Frequency
type: QuantityVariable
definition: Frequency of Fresh Vegetable Consumption.
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Diet Quantity
type: Class

Increased Body Weight
subclass of: Body Weight Quality
type: Class
subclass of: Restriction
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
  on property: isAttributeOf
definition: BMI > 25
type: QualityValue
notation: 72

picomole
notation: pmol
type: SIO_000074

Cerebral Malaria
subclass of: Malaria
type: Class
type: QualityValue
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
notation: 126

Initial concentration higher than the highest standard
subclass of: SIO_001167
type: Class

High-Performance Liquid Chromatography-Mass Spectrometry
definition: Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. Therefore, LC-MS may be applied in a wide range of sectors including biotechnology, environment monitoring, food processing, and pharmaceutical, agrochemical, and cosmetic industries.
subclass of: Mass Spectrometer
subclass of: Liquid Chromatography–Mass Spectrometer
type: Class
subclass of: High-Performance Liquid Chromatography
was approved by: chear-kb:PER-Jim-McCusker

femtogram
type: SIO_000074
notation: fg

Early Childhood Vigilance Test
type: Class
subclass of: Neurocognitive Assessment
definition: a computer-based assessment of sustained attention during which the child is required to watch a screen where various animated stimuli disappear and reappear

Peripheral Blood Mononuclear Cell
type: Class
subclass of: Cell
definition: Any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.

2, 2', 4, 4'-Tetrabromodiphenyl ether
notation: BDE47
subclass of: Polybrominated Diphenyl Ether
type: Class
editorial note: To Do: align with CHEBI.

quantity of sample insufficient for analysis
type: Class
subclass of: SIO_001167

Biomolecule
subclass of: Biospecimen
definition: A biospecimen that is composed of molecular entities.
type: Class

Perfluoroheptanoic acid
subclass of: PFC
type: Class
notation: PFHPA

Dilution required
subclass of: SIO_001167
type: Class

3-hydroxybenzo[c]-phenanthrene
type: Class
notation: BCP3
subclass of: PAH

cis-vaccenic acid
subclass of: Fatty Acid
type: Class
notation: C181N7
definition: The cis isomer of vaccenic acid.

Silver
type: Class
subclass of: Metal
notation: Ag
definition: Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.

Canned Food Consumption Frequency
subclass of: Diet Quantity
editorial note: Also want to list this under Environmental Exposures (b/c canned food has chemicals in the lining so sometimes it is used as a proxy)
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class
definition: Frequency of Canned Food Consumption.
type: QuantityVariable

Titanium
subclass of: Metal
type: Class
notation: Ti
definition: TITANIUM is a dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)

thawed and hemolyzed (covers all three levels)
type: Class
subclass of: SIO_001167

Personal Product Use
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Personal Product Use Indicator Class
subclass of: StudyIndicator

Sample frozen
type: Class
subclass of: SIO_001167

Bisphenol F
type: Class
notation: BPF
subclass of: Environmental Phenol

High Performance Liquid Chromatography - Tandem Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS (Tandem MS) is the combination of two mass analyzers in one mass spec instrument.
subclass of: Liquid Chromatography - Tandem Mass Spectrometer
subclass of: High-Performance Liquid Chromatography-Mass Spectrometry

4-Chlorophenol
subclass of: Environmental Phenol
notation: MCP4
type: Class
definition: P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible. Used as an intermediate in organic synthesis of dyes and drugs.

arachidonic acid
subclass of: Fatty Acid
type: Class
notation: C204N6
definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.

No Hct, Hct=40 assumed
subclass of: SIO_001167
type: Class

Failed negative control
subclass of: SIO_001167
type: Class

o-Xylene
definition: O-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
notation: OXY
subclass of: Volatile Organic Compound
type: Class

mono-benzyl phthalate
notation: mBzP
type: Class
editorial note: Is this a repeat of MBP?
subclass of: Phthalate

Public Insurance
type: Class
notation: 79
subclass of: Insurance
type: QualityValue

N-Ace-S- (3, 4-Dihidxybutl)-L-Cys(ng/mL)
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: VOCDHB
type: Class

Quit Smoking Before Pregnancy
subclass of: Pregnancy Characteristic
subclass of: Prenatal Nonsmoker
subclass of: Quit Smoking
type: Class
definition: A Previous Smoker who Quit Smoking Before Pregnancy
notation: 81
type: QualityValue

gram per milliliter
notation: g/ml
type: SIO_000074

Arsenic Species
type: Class
subclass of: Targeted Analyte
definition: A molecular entity with arsenic components.

mono-hexyl phthalate
subclass of: Phthalate
notation: mHxP
type: Class

Macromolecule
type: Class
subclass of: Biomolecule
definition: A very large molecule, such as protein, commonly created by polymerization of smaller subunits (monomers). They are typically composed of thousands of atoms or more. The most common macromolecules in biochemistry are biopolymers (nucleic acids, proteins, carbohydrates and polyphenols) and large non-polymeric molecules (such as lipids and macrocycles).

N-Acel-S-(2, 2-Dichlorvinyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOC2DC
type: Class

katal per cubic meter
type: SIO_000074
notation: kat/m3

Irregular result, no concentration reported
type: Class
subclass of: SIO_001167

Bisphenol S
type: Class
notation: BPS
subclass of: Environmental Phenol

microgram per milliliter
type: SIO_000074
notation: µg/ml

lumen
notation: lm
type: SIO_000074

Greater than 99th percentile
subclass of: SIO_001167
type: Class

Son
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010048
type: Class
definition: A son is a male offspring; a boy or man in relation to his parents.
subclass of: Child

pixels per millimeter
notation: p/mm
type: SIO_000074

Weight for Height Z-Score
definition: Z-Score of the weight/height ratio at a given age.
type: Class
subclass of: SIO_001245
subclass of: Z-Score
type: QuantityVariable

3-phenoxybenzoic acid
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
notation: PBA

4-hydroxybenzophenone
type: Class
notation: OH4BP
subclass of: Benzophenone

Buccal Cell
subclass of: Cell
definition: Cells collected from the inner epithelium of the cheek
type: Class

mono (6-COOH-2-methylheptyl) phthalate
type: Class
notation: MCOMHP
subclass of: Phthalate

From Conception
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
subclass of: Relative Time
type: Class
definition: A time in relation to a conception

Neighbor
subclass of: Demographic
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000485
definition: A person living near or next door to another person.
subclass of: SIO_000016
type: Class

Hemolyzed (covers all three levels) and debris present
type: Class
subclass of: SIO_001167

Unplanned Caesarian Section
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 23
subclass of: Caesarian Section
type: QualityValue
definition: Had an unplanned caesarian section.

Analysis Mode
definition: Analysis Mode
type: QualityVariable
type: Class
subclass of: SampleIndicator

Multiplex real-time PCR
type: Class
subclass of: Polymerase Chain Reaction

Ever Smoked
notation: 136
type: Class
definition: The quality of having smoking in the past.
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Smoking Status
type: QualityValue

Smoking Status
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: QualityVariable
subclass of: SIO_001326
type: Class
definition: An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history
editorial note: We need to discuss this entire hierarchy.

count per molar second
type: SIO_000074
notation: 1/Ms

mono-(2-ethyl-5-carboxypentyl) phthalate
subclass of: Phthalate
type: Class
editorial note: Duplicate of MCEPP?
notation: mECPP

Household Appliance Count
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Housing Characteristic
definition: Total number of appliances that can be found in the home.
type: QuantityVariable
subclass of: SIO_000794

Bodily Fluid
definition: Liquids originating from inside the bodies of living people. They include fluids that are excreted or secreted from the body, and body water that normally is not.
type: Class
subclass of: Biospecimen

Ultra High Performance Liquid Chromatography Instrument
subclass of: High-Performance Liquid Chromatography
type: Class
definition: Modern HPLC systems have been improved to work at much higher pressures, and therefore are able to use much smaller particle sizes in the columns (<2 μm). These "Ultra High Performance Liquid Chromatography" systems or UHPLCs can work at up to 120 MPa (17, 405 lbf/in^2), or about 1200 atmospheres.
was approved by: chear-kb:PER-Jim-McCusker

Acculturation
type: Class
definition: Acculturation explains the process of cultural change and psychological change that results following meeting between cultures. This metaclass contains all classes that measure this process.
subclass of: StudyIndicator
was approved by: chear-kb:PER-Jeanette-Stingone

Benzene
notation: BZ
type: Class
definition: Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
subclass of: Volatile Organic Compound

mono-2-ethyl-5-hydroxyhexyl terephthalate (DEHTP)
notation: MEHHTP

2, 3, 4, 6-Tetrachlorophenol
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)
notation: TeCP2346
subclass of: Environmental Phenol
type: Class

Mandelic acid
editorial note: To Do: align with CHEBI.
notation: MA
subclass of: Volatile Organic Compound
type: Class

Atomic Spectroscopy
type: Class
subclass of: Spectroscopy

4-hydroxyphenanthrene
subclass of: PAH
notation: PHEN4
type: Class

Granulocyte-macrophage colony-stimulating factor
subclass of: SIO_010043
notation: GMCSF
type: Class

Iodine
type: Class
definition: Iodine is a nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
notation: I
subclass of: Element

Drug History
type: QualityVariable
subclass of: Alcohol, Tobacco, and Illicit Drug Use
notation: 14
type: Class

square centimeter
type: SIO_000074
notation: cm2

Dental Fillings
notation: 13
type: Class
subclass of: Oral Health
type: QualityValue

First Trimester
subclass of: SIO_000417
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
definition: From pregnancy week 1 through 12 and includes conception. Conception is when the sperm fertilizes the egg. The fertilized egg then travels down the fallopian tube and attaches to the inside of the uterus, where it begins to form the embryo and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus).
subclass of: From Conception

2, 2', 4, 4', 5, 6'-Hexabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE154
type: Class
editorial note: To Do: align with CHEBI.

Whole Blood
subclass of: Bodily Fluid
type: Class
definition: A fluid that is composed of blood plasma and erythrocytes. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Blood][database_cross_reference: https://github.com/obophenotype/uberon/issues/9][database_cross_reference: FMA:9670]

Bisphenol A
definition: 4, 4'-isopropylidenediphenol is a white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)
type: Class
subclass of: Environmental Phenol
notation: BPA

N-Ethyl Perfluorooctane sulfonamido acetic acid
notation: NETFOSAA

mono-carboxy isooctyl phthalate
type: Class
subclass of: Phthalate
notation: mCIOP

Interleukin-4
subclass of: SIO_010043
type: Class
notation: IL4

skin fold thickness, tricep
subclass of: SampleIndicator
type: Class

Value greater than ULOQ
type: Class
subclass of: SIO_001167

Diet and Nutrition
definition: Diet and Nutrition Indicator
editorial note: • [WARNING] SDD_00014: The Attributes: [sio:SpecificGravity] are subclasses of neither hasco:StudyIndicator nor hasco:SampleIndicator .
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator

gigabyte
type: SIO_000074
notation: GB

N-ac-S-(2-carbmo-2-hydxel)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCGAM
type: Class
editorial note: To Do: align with CHEBI.

meter per second per second
notation: m/s2
type: SIO_000074

cubic meter per kilogram
notation: m3/kg
type: SIO_000074

2, 2', 4'-Tribromodiphenyl ether
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
notation: BDE17

C-C motif chemokine 20
subclass of: SIO_010043
notation: MIP3A
type: Class

kelvin
type: SIO_000074
notation: K

Other GI Disease
editorial note: This is a temp concept that needs addressing
subclass of: Medical History
type: Class
subclass of: SIO_010299
type: QualityValue
notation: 69

Electron Transfer Dissociation (ETD)
subclass of: TandemMassSpectrometry
type: Class

Polygamous
type: QualityValue
subclass of: Marital Status
type: Class
notation: 45
definition: A type of living arrangement or mating system in which at least one member of a relationship has more than one mate.

Ancestor
definition: An ancestor or forebear is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth). Ancestor is "any person from whom one is descended. In law the person from whom an estate has been inherited."
subclass of: Relative
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Descendant
    intersection of: SIO_000485
was approved by: chear-kb:PER-Jeanette-Stingone

sievert
type: SIO_000074
notation: Sv

4, 4'-DDE
type: Class
subclass of: Organochlorine Compound
notation: PPDDE

Perfluorobutanoic acid
notation: PFBA
type: Class
subclass of: PFC

blood monocyte count
type: Class
subclass of: SIO_000794

milligram per gram
type: SIO_000074
notation: mg/g

Serum
definition: Liquid derived from blood plasma that has clotting factors removed. [database_cross_reference: http://en.wikipedia.org/wiki/Serum_(blood)][database_cross_reference: http://orcid.org/0000-0002-6601-2165]
type: Class
subclass of: Blood Component

N-A-S-(1-HydrxMet)-2-Prpn)-L-Cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCMB1
subclass of: Volatile Organic Compound

Private Insurance
notation: 103
type: Class
subclass of: Private Insurance or Self Pay
type: QualityValue

3-Chlorophenol
definition: PHYSICAL DESCRIPTION: White crystals with an odor of phenol. Sinks in and slowly dissolves in water. (NTP, 1992)
notation: MCP3
subclass of: Environmental Phenol
type: Class

Diet Treatment Medical Therapy
definition: Diet Treatment is a form of Medical Therapy.
type: Class
notation: 26
subclass of: Medical Therapy Procedure
type: QualityValue
was approved by: chear-kb:PER-Jeanette-Stingone

Matrilysin
notation: MMP7
type: Class
subclass of: SIO_010043

Thallium
subclass of: Metal
notation: Tl
type: Class
definition: THALLIUM is a heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.

Health Maintenance Organization Insurance
type: QualityValue
subclass of: Insurance
notation: 49
type: Class

Interleukin-6
definition: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
subclass of: SIO_010043
notation: IL6
subclass of: Biological Response
type: Class

Unemployment
definition: The state of not having a job.
type: QualityValue
subclass of: Occupation
notation: 67
type: Class

Race
subclass of: Demographic
subclass of: SIO_000475
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityVariable

Post-Pregnancy
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000417
subclass of: From Birth
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000582
definition: The period after birth.

Non-Hispanic Ethnicity
definition: Non-Hispanic Ethnicity
notation: 58
type: QualityValue
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Ethnicity

Birth
type: Class
subclass of: Beginning
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000417
subclass of: From Birth
definition: The ending of a pregnancy by one or more babies leaving a woman's uterus by vagina passage or c-section.

microunits per milliliter
type: SIO_000074
notation: µU/mL

Vaginal Birth
notation: 24
editorial note: Again, can we add a delivery class
subclass of: SIO_000582
subclass of: Pregnancy Characteristic
type: QualityValue
definition: Had a birthing occur via the vagina.
subclass of: Route Of Delivery
type: Class

nanogray
notation: nGy
type: SIO_000074

2, 3, 5, 6-Tetrachlorophenol
notation: TeCP2356
definition: PHYSICAL DESCRIPTION: Leaflets (from ligroin) or light beige powder. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

2, 2', 4, 4', 5, 5'-Hexabromodiphenyl ether
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Polybrominated Diphenyl Ether
notation: BDE153

Benzophenone
subclass of: Targeted Analyte
type: Class

Lipemic and turbid
type: Class
subclass of: SIO_001167

Colorimetric Assay
type: Class
subclass of: SIO_001007

Liquid Chromatography Instrument
subclass of: Chromatography Instrument
was approved by: chear-kb:PER-Jim-McCusker
definition: A separation technique in which the mobile phase is a liquid. It can be carried out either in a column or a plane. Present day liquid chromatography that generally utilizes very small packing particles and a relatively high pressure is referred to as high performance liquid chromatography (HPLC).
type: Class

Hispanic or Latino Ethnicity
notation: 47
subclass of: Ethnicity
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term “Spanish origin” can also be used in addition to “Hispanic or Latino.”
type: QualityValue

Interleukin-17A
type: Class
notation: IL17A
subclass of: SIO_010043

From Birth
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: SIO_000582
  on property: inRelationTo
subclass of: Relative Time
definition: A time in relation to a birth

Protocatechuic acid ethyl ester
subclass of: Environmental Phenol
type: Class
notation: OHEtP

Divorced
definition: Indicates a person whose marriage has been legally dissolved and has not remarried.
subclass of: Unmarried
type: Class
type: QualityValue
notation: 40

Methyl mercury (CH3Hg+)
type: Class
notation: CH3Hg
subclass of: Mercury Species

Direct Mercury Analyzer
definition: Direct mercury analysis incorporates the following sequence: thermal decomposition, catalytic conversion, amalgamation, and atomic absorption spectrophotometry. Controlled heating stages are implemented to first dry and then thermally decompose a sample introduced into a quartz tube. A continuous flow of oxygen carries the decomposition products through a hot catalyst bed where halogens, nitrogen, and sulfur oxides are trapped. All mercury species are reduced to Hg(0) and are then carried along with reaction gases to a gold amalgamator where the mercury is selectively trapped. All nonmercury vapors and decomposition products are flushed from the system by the continuous flow of gas. The amalgamator is subsequently heated and releases all trapped mercury to the single-beam, fixed-wavelength atomic absorption spectrophotometer. Absorbance is measured at 253.7 nm as a function of mercury content
subclass of: PhysicalInstrument
was approved by: chear-kb:PER-Jim-McCusker
type: Class

Domestic Partnership
definition: Indicates a person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered.
type: QualityValue
type: Class
notation: 42
subclass of: Unmarried

Not Current Student
type: Class
notation: 141
type: QualityValue
definition: The state of an individual not currently engaged in educational activity as a pupil.
subclass of: SIO_001326

microcurie
notation: µCi
type: SIO_000074

Platelet
subclass of: Blood Component
type: Class
definition: A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.

Targeted Sequencing
definition: Nucleic acid sequencing that limits the scope of sequencing by filtering out portions of the nucleic acids that do not meet some criteria.
subclass of: Nucleic Acid Sequencing
type: Class

octadecanoic acid
notation: C180
subclass of: Fatty Acid
definition: A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
type: Class

Element
type: Class
subclass of: Targeted Analyte

Inductively Coupled Plasma Mass Spectrometry
subclass of: MassSpectrometry
type: Class

micromolar
type: SIO_000074
notation: µM

neuron
type: Class
subclass of: Cell

Tetrachloroethene
type: Class
notation: TCE
definition: TETRACHLOROETHYLENE is a chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
subclass of: Volatile Organic Compound

Prenatal Nonsmoker
notation: 76
type: Class
definition: Could be a former smoker or a non-smoker, so neither should be encoded as the superclass.
subclass of: Non-smoker
type: QualityValue
editorial note: Should this be a subClassOf PregnancyCharactistic as well?

Esophagus
type: Class
subclass of: SIO_010003

SIO_000554
type: QualityValue
notation: 134

Adolescent Period
subclass of: From Birth
type: Class
definition: The age span ranging from adolescence to adulthood
subclass of: Restriction
  all values from: Class
    intersection of: SIO_000582
  on property: inRelationTo
subclass of: SIO_000417

SIO_000980
notation: 107
type: QualityValue

Ethyl paraben
subclass of: Paraben
notation: EtPB
definition: Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of ethylparaben is Allergens.
type: Class

Biospecimen
type: Class
subclass of: SIO_010412
subclass of: SampleIndicator
definition: A biological laboratory specimen held by a biorepository for research. Such a specimen would be taken by sampling so as to be representative of any other specimen taken from the source of the specimen. When biological specimens are stored, ideally they remain equivalent to freshly-collected specimens for the purposes of research.

Education Grade 1
type: QualityValue
subclass of: Some Elementary School
definition: Finished grade 1
notation: 113
type: Class

cubic meter
notation: m3
type: SIO_000074

milligram per milliliter
type: SIO_000074
notation: mg/ml

Elective Caesarian Section
definition: A caesarian section that was chosen by the mother but was not medically necessary.
notation: 19
type: Class
subclass of: Caesarian Section
type: QualityValue

Mercapturic acids of acrolein and crotonaldehyde
subclass of: PAH
notation: AMA
type: Class

3-Methylhippuric acid + 4-Methylhippuric acid
subclass of: Volatile Organic Compound
notation: MHA34
type: Class
editorial note: To Do: align with CHEBI.

2-Methylhippuric acid
type: Class
editorial note: To Do: align with CHEBI.
notation: MHA2
subclass of: Volatile Organic Compound

2, 2', 3, 3', 4, 4', 5, 5', 6, 6'-Decabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.
notation: BDE209
type: Class

Relative Time
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Process
type: Class
definition: A time in relation to an event
subclass of: SIO_000391

Interleukin-9
type: Class
notation: IL9
subclass of: SIO_010043

Blood Component
subclass of: Bodily Fluid
type: Class
definition: A derivable component of whole blood.

SIO_010048
notation: 111
type: QualityValue

Gestational Age
type: QuantityVariable
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization
subclass of: Age
subclass of: Birth Outcome

Interleukin-12 subunit alpha
notation: IL12P70
subclass of: SIO_010043
type: Class

Dimethylarsinic Acid
subclass of: Arsenic Species
type: Class
notation: Dimethylarsinic Acid

Gravida
subclass of: Pregnancy Characteristic
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class
subclass of: SIO_000794
definition: Pregnancy Count, regardless of whether pregnancy was carried to Term.
type: QuantityVariable

Used Only Anti Malarials or No Medications
notation: 139
type: QualityValue
subclass of: Prescription Medication and Dietary Supplements
type: Class

Mono-2-(carboxymethyl) hexyl phthalate
type: Class
notation: MCMHP
subclass of: Phthalate

Developmental Quality
definition: Refers to which stage of development a person is in.
type: QualityVariable
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000475

N-Ace-S-(N-methlcarbamoyl)-L-cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCAMC
subclass of: Volatile Organic Compound

Occupation
subclass of: Socioeconomic Status
subclass of: Demographic
type: Class
definition: An individual attribute that is the usual or principal work or business of an individual.
subclass of: SIO_000016
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityVariable

SIO_000981
notation: 108
type: QualityValue

m-Xylene*
notation: MXY
subclass of: Volatile Organic Compound
definition: M-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
type: Class

Multiracial
type: Class
definition: Having ancestors of several or various races.
editorial note: Not part of current prov for Race. Should we remove this concept?
notation: 54
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityValue
subclass of: Race

counts per minute
type: SIO_000074
notation: cpm

ampere
type: SIO_000074
notation: A

Collision-Induced Dissociation (CID)
subclass of: TandemMassSpectrometry
type: Class

mass-to-charge ratio
type: SIO_000074
notation: Th

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
notation: AMCC
editorial note: To Do: align with CHEBI.

decibel
type: SIO_000074
notation: dB

Gas Chromatographer–Mass Spectrometer
subclass of: Mass Spectrometer
type: Class
definition: Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples, including that of material samples obtained from planet Mars during probe missions as early as the 1970s. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification. Like liquid chromatography–mass spectrometry, it allows analysis and detection even of tiny amounts of a substance.
subclass of: Gas Chromatography Instrument
was approved by: chear-kb:PER-Jim-McCusker

alpha-linolenic acid
subclass of: Fatty Acid
definition: A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect.
type: Class
notation: C183N3

Second Trimester
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000417
definition: From week 13 through 28. Around the middle of the second trimester, movement of the fetus may be felt. At 28 weeks, more than 90% of babies can survive outside of the uterus if provided with high-quality medical care.
subclass of: From Conception

Insurance
type: QualityVariable
subclass of: Healthcare Access
subclass of: Socioeconomic Status
type: Class

Known Food Allergies
subclass of: Medical History
type: Class
type: QualityVariable

Blackbody Infrared Radiative Dissociation (BIRD)
subclass of: TandemMassSpectrometry
type: Class

Cousin
subclass of: Relative
type: Class
definition: A person belonging to the same extended family.

Some High School
definition: Education Level of Some High School
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
notation: 87
type: QualityValue
subclass of: High School or Less

N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
notation: HPMA2
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

First Year of the Common Era
type: NamedIndividual

Some Elementary School
type: Class
definition: Attended Some Elementary School
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityValue
notation: 86
subclass of: High School or Less

Strontium
definition: STRONTIUM is an element of the alkaline earth family of metals. It has the atomic symbol Sr, atomic number 38, and atomic weight 87.62.
notation: Sr
subclass of: Metal
type: Class

Interleukin-2
type: Class
notation: IL2
subclass of: SIO_010043

glucose
type: Class
subclass of: Analyte
definition: An aldohexose used as a source of energy and metabolic intermediate.

count per nanomolar
type: SIO_000074
notation: 1/nM

monoisononyl phthalate
notation: MIP
type: Class
subclass of: Phthalate
editorial note: Duplicate of mINP?

Paraben
type: Class
subclass of: Targeted Analyte

parts per thousand
notation: ppth
type: SIO_000074

billion parts per microgram
type: SIO_000074
notation: x109 µL

TermBirth
type: Class
notation: 97
type: QualityValue
subclass of: Birth Outcome

Mother
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Parent
subclass of: Restriction
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010052
  on property: isRoleOf
definition: A mother is the female parent of a child. Mothers are women who inhabit or perform the role of bearing some relation to their children, who may or may not be their biological offspring. Thus, dependent on the context, women can be considered mothers by virtue of having given birth, by raising their child(ren), supplying their ovum for fertilisation, or some combination thereof. Such conditions provide a way of delineating the concept of motherhood, or the state of being a mother. Women who meet the third and first categories usually fall under the terms 'birth mother' or 'biological mother', regardless of whether the individual in question goes on to parent their child. Accordingly, a woman who meets only the second condition may be considered an adoptive mother, and those who meet only the third a surrogacy mother. The above concepts defining the role of mother are neither exhaustive nor universal, as any definition of 'mother' may differ based on how social, cultural, and religious roles are defined.
type: Class

Microplate Reader
was approved by: chear-kb:PER-Jim-McCusker
subclass of: PhysicalInstrument
type: Class
definition: Instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 6-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well (8 by 12 matrix) with a typical reaction volume between 100 and 200 µL per well. Higher density microplates (384- or 1536-well microplates) are typically used for screening applications, when throughput (number of samples per day processed) and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 µL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.

N-Acetyl-S-(n-propyl)-L-cysteine(ng/mL)
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class
notation: VOCBPM

Metalloproteinase inhibitor 1
type: Class
notation: TIMP1
subclass of: SIO_010043

platelet count
type: Class
subclass of: SIO_000794

Trimethylarsine oxide
notation: Trimethylarsine oxide
subclass of: Arsenic Species
type: Class

Benzyl paraben
notation: BzPB
definition: Benzylparaben is a Standardized Chemical Allergen. The physiologic effect of benzylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of benzylparaben is Allergens.
type: Class
subclass of: Paraben

Niobium
subclass of: Metal
notation: Nb
definition: Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)
type: Class

Interleukin-22
type: Class
notation: IL22
subclass of: SIO_010043

PCB153
type: Class
notation: PCB153
subclass of: Polychlorobiphenyl

Perfluorobutanesulfonic acid
subclass of: PFC
type: Class
notation: PFBS

Carbon Tetrachloride
definition: CARBON TETRACHLORIDE is a solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
subclass of: Volatile Organic Compound
type: Class
notation: CTET

active eosinophilic esophagitis
type: Class
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of more than 25 eosinophils per high-power field area, or 0.158 mm^2 (400x).
equivalent class: Restriction
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: hasAttribute
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
  on property: isPhenotypeOf

4, 4'-(hexafluoroisopropylidene)-dephenol
notation: BPAF

Arsenocholine
subclass of: Arsenic Species
type: Class
notation: Arsenocholine

Some Middle School
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: High School or Less
definition: Attended Some Middle School
type: QualityValue
notation: 90

Perfluorohexanoic acid
type: Class
notation: PFHxA
subclass of: PFC

SIO_010052
notation: 110
type: QualityValue

2-Aminothiazoline-4-carboxylic acid
editorial note: To Do: align with CHEBI.
type: Class
notation: ATCA
subclass of: Volatile Organic Compound

Difference
subclass of: SIO_000052
definition: Variables derived from taking the difference of two other variables. For example, the first difference of a time series {yt} is defined as Dyt = yt - yt-1
type: Class

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCMB3
subclass of: Volatile Organic Compound

Value below LLOQ, no LOD provided
subclass of: SIO_001167
type: Class

thawed and clotted
type: Class
subclass of: SIO_001167

Parity
type: QuantityVariable
subclass of: SIO_000794
subclass of: Pregnancy Characteristic
definition: The number of time that a viviparous organism has given birth
was approved by: chear-kb:PER-Jeanette-Stingone
type: Class

byte
notation: Byte
type: SIO_000074

2, 4, 5-Trichlorophenol
definition: Exposure to 2, 4, 5-trichlorophenol may occur during its production or use as a pesticide. Acute (short-term) dermal exposure to 2, 4, 5-trichlorophenol may burn skin in humans. It also irritates the eyes, nose, pharynx, and lungs in humans. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of 2, 4, 5-trichlorophenol in humans. In one study, slight degenerative changes were observed in the liver and kidneys of rats chronically exposed to 2, 4, 5-trichlorophenol in their diet. EPA has classified 2, 4, 5-trichlorophenol as a Group D, not classifiable as to human carcinogenicity. PHYSICAL DESCRIPTION: Colorless needles, gray flakes or off-white lumpy solid. Phenolic odor. Formerly used as a fungicide and bactericide.
type: Class
notation: TCP245
subclass of: Environmental Phenol

Tumor necrosis factor
notation: TNFA
type: Class
subclass of: SIO_010043
subclass of: Biological Response
definition: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).
label: TNF-alpha

katal per liter
notation: kat/l
type: SIO_000074

SYNAPT G2-Si Mass Spectrometer
subclass of: Hydrogen–Deuterium Exchange Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class

In Vitro Fertilization
notation: 50
type: QualityValue
subclass of: Assisted Reproductive Therapy
type: Class

2, 4, 4'-Tribromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE28
editorial note: To Do: align with CHEBI.
type: Class

Boron
definition: A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY.
subclass of: Metal
notation: B
type: Class

Metalloproteinase inhibitor 2
notation: TIMP2
subclass of: SIO_010043
type: Class

Disease
type: Class
subclass of: SIO_010299
subclass of: Medical History

molal
notation: mol/kg
type: SIO_000074

Short sample; sample probe picked up incomplete volume first time
subclass of: SIO_001167
type: Class

Competitive-inhibition enzyme-linked immunosorbent assay
type: Class
subclass of: enzyme-linked immunosorbent assay (ELISA)

Smoker
notation: 105
subclass of: Smoking Status
type: Class
definition: The quality of smoking cigarettes.
type: QualityValue

radian
notation: rad
type: SIO_000074

Technical School
notation: 96
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
type: QualityValue
definition: Attended a Technical School.
subclass of: Education

Color Object Association Test
subclass of: Neurocognitive Assessment
type: Class
definition: a reliable and a valid measure of declarative memory for healthy children ages 18-36 months, living in a disadvantaged community

N-Ace-S-(dimethylphenyl)-L-Cys(ng/mL)
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCDPM

Full Time Employment
definition: Employed for a standard number of hours of working time, at least 50% or 20 hours per week.
type: Class
notation: 64
subclass of: Occupation
type: QualityValue

femtomole
type: SIO_000074
notation: fmol

volt per meter
type: SIO_000074
notation: V/m

Matched Pair of Subjects
definition: A set of 2 subjects which result from a pairing process which assigns subject to a set based on a pairing rule/criteria
type: Class
subclass of: SIO_000616

picomolal
notation: pmolal
type: SIO_000074

Fatty Acid
type: Class
definition: Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax.
subclass of: Targeted Analyte

Proton Pump Inhibitor Treatment
type: QualityValue
type: Class
definition: Proton Pump Inhibitor Treatment as a form of medical therapy.
subclass of: Medical Therapy Procedure
editorial note: UPDATE: Yes, add the prescription medication, either as an indicator or as a class under Medical Therapy. Whichever works for the ontology. Why isn't this listed under prescription medication? How do you differentiate between medical therapy and prescription medication?
notation: 27

Mono-n-pentyl phthalate
editorial note: Duplicate of mPeP?
type: Class
subclass of: Phthalate
notation: MPP

Metabolite
subclass of: Small Molecule
definition: The intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
type: Class

Hemolyzed (covers all three levels) and contaminated
subclass of: SIO_001167
type: Class

volt
notation: Volt
type: SIO_000074

liter per kilogram
type: SIO_000074
notation: l/kg

Atomic Absorption Spectroscopy
type: Class
subclass of: Atomic Spectroscopy

Beryllium
type: Class
subclass of: Metal
notation: Be
definition: Beryllium. An element with the atomic symbol Be, atomic number 4, and atomic weight 9.01218. Short exposure to this element can lead to a type of poisoning known as BERYLLIOSIS.

diethyldithiophosphate
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
notation: DEDP

Ultra Performance Liquid Chromatography - Mass Spectrometer
subclass of: Ultra High Performance Liquid Chromatography Instrument
subclass of: Mass Spectrometer
type: Class
was approved by: chear-kb:PER-Jim-McCusker

Sibling
was approved by: chear-kb:PER-Jeanette-Stingone
definition: One of two or more individuals having one or both parents in common. A male sibling is a brother, and a female sibling is a sister. In most societies throughout the world, siblings often grow up together, thereby facilitating the development of strong emotional bonds. The emotional bond between siblings is often complicated and is influenced by factors such as parental treatment, birth order, personality, and personal experiences outside the family. However, there are cases where siblings grow up in separate homes, in different environments.
subclass of: Relative
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Sibling
    intersection of: SIO_000485
type: Class

2-hydroxyfluorene
notation: FLUO2
subclass of: PAH
type: Class

picosecond
notation: ps
type: SIO_000074

Fibrinogen Assay (Clauss method)
subclass of: SIO_001007
type: Class

Cord Blood
definition: Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Cord_blood]
type: Class
subclass of: Whole Blood
subclass of: Pregnancy Sample

6-hydroxychrysene
type: Class
subclass of: PAH
notation: CHRY6

Advanced Graduate Degree
notation: 4
type: QualityValue
subclass of: Education
type: Class
definition: Having earned a pos-baccalaureate degree

Mandelic acid(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCMAD
subclass of: Volatile Organic Compound

Red blood cells present
subclass of: SIO_001167
type: Class

Mercapturic acid of benzene
type: Class
notation: SPMA
subclass of: PAH

Chloroform
type: Class
definition: CHLOROFORM is a commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.
notation: CFRM
subclass of: Volatile Organic Compound

mono (5-carboxy-2-ethylpentyl) phthalate (DEHP)
subclass of: Phthalate
notation: MCEPP
type: Class

Atomic Emission Spectroscopy
subclass of: Atomic Spectroscopy
type: Class

colony forming unit
notation: cfu
type: SIO_000074

N-Acetyl-S-(1, 2-dichlorovinyl)-L-cysteine
subclass of: Volatile Organic Compound
notation: DCVMA12
editorial note: To Do: align with CHEBI.
type: Class

Alkyl Phosphate Pesticide Metabolite
subclass of: Targeted Analyte
type: Class

Biological Response
subclass of: StudyIndicator
editorial note: abolic_SDD_v1.xlsx
definition: Indicator of biological response to environmental exposure
type: Class

mono-2-heptyl phthalate
notation: mHpP
subclass of: Phthalate
type: Class

Alcohol Use
type: Class
notation: 83
type: QualityValue
subclass of: Alcohol, Tobacco, and Illicit Drug Use
definition: Uses Alcohol

Malarial Retinopathy
notation: 130
type: QualityValue
definition: Retinopathy due to malaria.
subclass of: Retinopathy
type: Class

Socioeconomic Status Index
editorial note: This is a specific index, derived from other variables. So, it should somehow be connected to this variables. Also, we may want to be more specific about the type of index that it is. Perhaps there should be a general SESIndex and then subclasses of specific measures?
subclass of: Socioeconomic Status
definition: A measure of SES.
type: Class
subclass of: SIO_000052
type: QuantityVariable

Gold
type: Class
definition: GOLD is a yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
subclass of: Metal
notation: Au

Fibrin present
subclass of: SIO_001167
type: Class

megabyte
type: SIO_000074
notation: MB

Perfluorooctanesulfonate
notation: PFDODA
type: Class
subclass of: PFC

Neighborhood Characteristic
definition: Neighborhood Characteristic Indicator Class
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator

Phenotype
subclass of: Medical History
type: Class

dots per inch
notation: dpi
type: SIO_000074

Gas Chromatographer-Tandem Mass Spectrometer
subclass of: Tandem Mass Spectrometer
subclass of: Gas Chromatographer–Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class
definition: MS/MS is the combination of two mass analyzers in one mass spec instrument.

RNA
subclass of: Macromolecule
type: Class

gamma-linolenic acid
subclass of: Fatty Acid
notation: C183N6
definition: A C18, ω-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.
type: Class

watt per meter kelvin
type: SIO_000074
notation: W/mK

attomole
notation: amol
type: SIO_000074

microeinstein per square meter per second
type: SIO_000074
notation: µeinstein/sm2

parts per quadrillion
notation: ppq
type: SIO_000074

Third Trimester
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000417
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
definition: From 29 weeks through 40 weeks.
type: Class
subclass of: From Conception

Targeted Analyte
definition: A targeted analyte is one that has been selected by the CHEAR program as a prioritized analyte for CHEAR lab hubs to measure.
type: Class
subclass of: Analyte
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator

watt
notation: watt
type: SIO_000074

Some College
subclass of: Higher Education
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
definition: Indicates that a person has attended college but that they did not receive any degree.
notation: 85
type: QualityValue

square millimeter
type: SIO_000074
notation: mm2

Hair
subclass of: Tissue
type: Class
definition: A filament, mostly protein, that grows from follicles found in the dermis[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Hair]

Interleukin-31
type: Class
notation: IL31
subclass of: SIO_010043

angstrom
type: SIO_000074
notation: Ang

Gestational Age at Birth
definition: Describes how far along a pregnancy is, usually measured in weeks, as measured at birth.
subclass of: Gestational Age
equivalent class: Class
  intersection of: Gestational Age
  intersection of: Restriction
    on property: measuredAt
    all values from: Birth
type: Class

Environmental Material
type: Class
subclass of: SampleIndicator
subclass of: SIO_010412

N-Acetyl-S-(trichlorovinyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: TCVMA
subclass of: Volatile Organic Compound
type: Class

millimeter
type: SIO_000074
notation: mm

Biological Sex
type: Class
type: QualityVariable
subclass of: Demographic

9-hydroxyfluorene
type: Class
subclass of: PAH
notation: FLUO9

Perfluroundecanoic acid
subclass of: PFC
type: Class
notation: PFUNDA

2, 4, 5, 6-Tetrachlorophenol
type: Class
subclass of: Environmental Phenol
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)
notation: TeCP2456

Cell

SIO_000982
type: QualityValue
notation: 106

parts per hundred
type: SIO_000074
notation: pph

Unusually high
type: Class
subclass of: SIO_001167

VCR Player Count
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
type: QuantityVariable
subclass of: Household Appliance Count
definition: Number of devices that play VCRs in the home.

Gravimetric Analysis Instrument
definition: Gravimetric analysis describes a set of methods used in analytical chemistry for the quantitative determination of an analyte (the ion being analyzed) based on its mass. The principle behind this type of analysis is that once an ion's mass has been determined as a unique compound, that known measurement can then be used to determine the same analyte's mass in a mixture, as long as the relative quantities of the other constituents are known.
type: Class
subclass of: PhysicalInstrument
was approved by: chear-kb:PER-Jim-McCusker

Replicate Number
subclass of: SampleIndicator
type: Class
definition: Replicate Number

Interstitial collagenase
notation: MMP1
subclass of: SIO_010043
type: Class

skin fold thickness, subscapular
type: Class
subclass of: SampleIndicator

Cerebrospinal fluid
definition: A clear, colorless fluid that is found in the brain and spinal cord.
subclass of: SIO_010046
type: Class

phthalic acid
definition: PHYSICAL DESCRIPTION: White crystals or fine white powder. (NTP, 1992)
type: Class
subclass of: Phthalate
notation: PA

8-hydroxy-2'-deoxyguanosine
subclass of: Biological Response
type: Class
definition: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.
subclass of: Biomolecule

milliliter
notation: ml
type: SIO_000074

Cellular debris present
type: Class
subclass of: SIO_001167

Atomic Fluorescence Spectroscopy Instrument
definition: a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light.
type: Class
subclass of: PhysicalInstrument
was approved by: chear-kb:PER-Jim-McCusker

Fenton Weighted Z-Score
subclass of: Class
  intersection of: SIO_001245
  intersection of: Restriction
    some values from: HHEAR_00504
    on property: wasDerivedFrom
  intersection of: Restriction
    some values from: Fenton Preterm Growth Chart
    on property: wasDerivedFrom
  intersection of: Restriction
    some values from: Gestational Age at Birth
    on property: wasDerivedFrom
type: Class
subclass of: Z-Score
subclass of: SIO_001245
type: QuantityVariable
subclass of: Birth Outcome
definition: Derived from Birth Weight, Gestational Age, and Child Sex
was approved by: chear-kb:PER-Jeanette-Stingone

Quantity of sample insufficient for repeat analysis
type: Class
subclass of: SIO_001167

N-Ace-S-(2-carbamoylethyl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCAAM
editorial note: To Do: align with CHEBI.
type: Class

hemoglobin measurement
type: Class
subclass of: Concentration

Parent
subclass of: Ancestor
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Child
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
was approved by: chear-kb:PER-Jeanette-Stingone
definition: A parent is the caretaker of a child (where "child" refers to offspring, not necessarily age). A biological parent is a person whose gamete resulted in a child, a male through the sperm, and a female through the ovum. Parents are first-degree relatives and have 50% genetic meet. A female can also become a parent through surrogacy. Some parents may be adoptive parents, who nurture and raise an offspring, but are not actually biologically related to the child. Orphans without adoptive parents can be raised by their grandparents or other family members.
type: Class

microliters per minute
notation: µL/min
type: SIO_000074

Cobalt
notation: Co
definition: COBALT is a trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
type: Class
subclass of: Metal

Step
type: Class
definition: A stepfamily is a family where at least one parent has children that are not genetically related to the other spouse or partner. Either one parent may have children from a previous relationship. Children in a stepfamily may live with one biological parent, or they may live with each biological parent for a period of time. In addition, visitation rights mean that children in stepfamilies often have contact with both biological parents, even if they permanently live with only one. A child is referred to as the stepchild, stepdaughter or stepson of their biological parent's new spouse, and that person as the stepparent, stepfather or stepmother of the child. A stepfather is the husband of one's mother, and not one's biological father. A stepmother is the wife of one's father, and not one's biological mother. A step-grandmother is the wife of one's grandfather, and not one's biological grandmother. A step-grandfather is the husband of one's grandmother, and not one's biological grandfather. Similarly, a stepbrother is the son of a stepparent who one is not biologically related to. A stepsister is the daughter of a stepparent to whom one is not biologically related. A step-grandson is the son of a stepson or stepdaughter who one is not biologically related to. A step-granddaughter is the daughter of a stepson or stepdaughter who one is not biologically related. A parent's spouse of the same sex may also count as a stepparent.
subclass of: Non-Biological Relative

Cognitive Task
subclass of: Neurocognitive Assessment
type: Class

Kaufman ABC Sequence Subscale
definition: Subscale of Kaufman ABC designed to measure the ability to solve problems by remembering and using an ordered series of images or ideas
type: Class
subclass of: Neurocognitive Assessment

Sickle Cell Anemia
subclass of: SIO_010299
type: QualityValue
notation: 122
subclass of: Medical History
type: Class
definition: A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.

picograms per milliliter
type: SIO_000074
notation: pg/mL

watt per steradian per square meter
notation: W/sr/m2
type: SIO_000074

Antimalarial
type: Class
notation: 120
subclass of: Medication
definition: A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
type: QualityValue

Hydroxycotinine (total)
type: Class
subclass of: Tobacco Metabolite
notation: HCOT
label: Hydroxycotinine
notation: HCOTT

PAH
subclass of: Volatile Organic Compound
type: Class

Phthalate
type: Class
subclass of: Targeted Analyte

Prescription Medication and Dietary Supplements
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Prescription Medication and Dietary Supplements are forms of medical treatment.

Consumed Alcohol
notation: 52
type: Class
type: QualityValue
subclass of: Alcohol Use

Urine grossly hematuric
subclass of: SIO_001167
type: Class

radian per second per second
notation: alpha
type: SIO_000074

p-Xylene*
subclass of: Volatile Organic Compound
notation: PXY
definition: P-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. Freezing point is 56°F. (USCG, 1999)
type: Class

Manganese
notation: Mn
type: Class
subclass of: Metal
definition: MANGANESE is a trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)

Obvious coarse debris
subclass of: SIO_001167
type: Class

Stress Frequency
type: Class
subclass of: SIO_000475
editorial note: Again, we might want to link this to a specific assessment?
definition: How frequently a person gets stressed.
type: QualityVariable
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Mental Health

Benzophenone-3
notation: BP3
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
subclass of: Environmental Phenol
type: Class
editorial note: Duplicate of OXB?

Torn bag (Mitest intact, capped)
subclass of: SIO_001167
type: Class

Nicotine (total)
type: Class
subclass of: Tobacco Metabolite
editorial note: To Do: align with CHEBI.
notation: NICT

newton per meter
notation: N/m
type: SIO_000074

Arsenic
type: Class
definition: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
subclass of: Metal
notation: As

Panel change
type: Class
subclass of: SIO_001167

Anatabine
notation: ANAT
type: Class
subclass of: Tobacco Metabolite

Cognitive Entity
type: Class
subclass of: Neurocognitive Assessment

PCB52
type: Class
notation: PCB52
subclass of: Polychlorobiphenyl

kilogram per square meter
type: SIO_000074
notation: kg/m2

Mono-n-octyl phthalate
subclass of: Phthalate
type: Class
notation: MOP

Limit of Detection
type: Class
definition: The lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%). The detection limit is estimated from the mean of the blank, the standard deviation of the blank and some confidence factor. Another consideration that affects the detection limit is the accuracy of the model used to predict concentration from the raw analytical signal.
subclass of: Concentration

Stromelysin-2
type: Class
notation: MMP10
subclass of: SIO_010043

mono-isopropyl phthalate
subclass of: Phthalate
editorial note: Duplicate of MiPP?
notation: mIPrP
type: Class

SIO_000784
type: QualityValue
notation: 109

Hydrogen–Deuterium Exchange Mass Spectrometer
type: Class
definition: Hydrogen–deuterium exchange mass spectrometry can determine the overall deuterium content of molecules which have undergone H/D exchange. Because of the sample preparation required, it is typically considered to provide an accurate measurement of non-exchangeable hydrogen atoms only.
was approved by: chear-kb:PER-Jim-McCusker
subclass of: Mass Spectrometer

gram
type: SIO_000074
notation: g

kilogram meter per second
notation: kg.m/s
type: SIO_000074

Education Grade 3
type: QualityValue
notation: 115
definition: Finished grade 3
type: Class
subclass of: Some Elementary School

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
notation: HPMMA
subclass of: Volatile Organic Compound

Age
type: Class
subclass of: Demographic
type: QuantityVariable

absorbance unit
notation: AU
type: SIO_000074

Severe Malarial Anemia
subclass of: Anemia
type: QualityValue
notation: 127
definition: In holoendemic transmission areas, Severe Malarial Anemia (SMA) is the primary clinical manifestation of severe childhood malaria, with cerebral malaria occurring only in rare cases. Mortality rates from SMA can exceed 30% in pediatric populations residing in holoendemic transmission areas. The pathophysiological processes that contribute to SMA involve direct and indirect destruction of parasitized and non-parasitized red blood cells (RBCs), inefficient and/or suppression of erythropoiesis, and dyserythropoiesis.
type: Class

microsievert
notation: µSv
type: SIO_000074

Entity
subclass of: ScienceIndicator
type: Class

kilogram per cubic meter
type: SIO_000074
notation: kg/m3

Retina
definition: The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
subclass of: SIO_010003
type: Class

diastolic blood pressure
subclass of: SampleIndicator
type: Class

Solid-Phase Sandwich ELISA
type: Class
subclass of: Sandwich ELISA
was approved by: chear-kb:PER-Jim-McCusker

tesla
type: SIO_000074
notation: Tesla

Repeat Caesarian Section
type: QualityValue
definition: Had Repeat Caesarian Section
subclass of: Caesarian Section
notation: 21
type: Class

Arsenobetaine
notation: Arsenobetaine
subclass of: Arsenic Species
type: Class

Cis-Chlordane
notation: CCHL
type: Class
subclass of: Organochlorine Compound

Sandwich ELISA
subclass of: enzyme-linked immunosorbent assay (ELISA)
definition: Sandwich ELISAs involve attachment of a capture antibody to a solid phase support. Samples containing known or unknown antigen are then added in a matrix or buffer that will minimize attachment to the solid phase. An enzyme-labeled antibody is then added for detection.
type: Class

1-hydroxybenz[a]anthacene
type: Class
notation: BAA1
editorial note: Only found in one journal article, no where else. Maybe mis-spelled?
subclass of: PAH

Moderately hemolyzed
subclass of: SIO_001167
type: Class

watt per square meter
notation: W/m2
type: SIO_000074

Clinical Measurement
subclass of: Physical and Mental Assessment
type: Class
definition: A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation.

kilogram per meter
notation: kg/m
type: SIO_000074

volume percentage
type: SIO_000074
notation: %(v/v)

Neurocognitive Assessment
type: Class
subclass of: Physical and Mental Assessment

Urine
type: Class
definition: Excretion that is the output of a kidney [database_cross_reference: http://en.wikipedia.org/wiki/Urine][database_cross_reference: https://github.com/geneontology/go-ontology/issues/11025]
subclass of: Bodily Fluid

N-methyl Perfluorooctane sulfonamido acetic acid
subclass of: PFC
type: Class
notation: NMFOSAA

Placenta
type: Class
subclass of: Pregnancy Sample
definition: Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. [database_cross_reference: http://en.wikipedia.org/wiki/Placenta][database_cross_reference: http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm]
subclass of: Tissue

Pregnancy Complication
type: QualityValue
type: Class
notation: 75
subclass of: Pregnancy Characteristic

Red Blood Cell
type: Class
subclass of: Blood Component
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.

formazin nephelometric unit
type: SIO_000074
notation: FNU

radian per second
notation: rad/s
type: SIO_000074

Gas Chromatography Instrument
definition: Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture (the relative amounts of such components can also be determined). In some situations, GC may help in identifying a compound. In preparative chromatography, GC can be used to prepare pure compounds from a mixture.
type: Class
was approved by: chear-kb:PER-Jim-McCusker
subclass of: Chromatography Instrument

Shotgun Lipidomics
type: Class
subclass of: Electrospray Ionization Mass Spectrometry

Analyzed at a later date than rest of samples on worksheet (not a repeat)
type: Class
subclass of: SIO_001167

Interferon gamma
subclass of: SIO_010043
type: Class
notation: IFNG

liter
type: SIO_000074
notation: L

Tobacco Metabolite
type: Class
subclass of: Targeted Analyte

Room Count
subclass of: SIO_000794
type: QuantityVariable
definition: Total Number of Rooms in the Home
subclass of: Housing Characteristic
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone

Methylation Assay
definition: An assay that measures the methylation levels of sections of a genome.
type: Class
subclass of: SIO_001007

Gas Chromatography
type: Class
subclass of: Chromatography

2-hydroxychrysene
subclass of: PAH
notation: CHRY2
type: Class

3-hydroxyfluorene
type: Class
notation: FLUO3
subclass of: PAH

Specimen analyzed in singlicate for an assay that requires duplicates
subclass of: SIO_001167
type: Class

blood insulin-like growth factor 1 level
subclass of: SampleIndicator
type: Class

poise
notation: Poise
type: SIO_000074

mole fraction
type: SIO_000074
notation: chi

Genotype
subclass of: Medical History
type: Class

Part Time Employment
notation: 65
type: QualityValue
definition: Employment involving less than the standard or customary working time.
subclass of: Occupation
type: Class

Vacuum Cleaner Count
was approved by: chear-kb:PER-Jeanette-Stingone
type: QuantityVariable
definition: Number of appliances in home used for cleaning rugs.
subclass of: Household Appliance Count
type: Class

Perfluorodecanoic acid
subclass of: PFC
type: Class
notation: PFDA

Childhood Cohort Study
subclass of: CohortStudy
type: Class

3, 4-Dihydroxy-benzoic acid methyl ester
subclass of: Environmental Phenol
type: Class
notation: OHMeP

count unit
notation: count
type: SIO_000074

degree Celsius
notation: C
type: SIO_000074

picometer
notation: pm
type: SIO_000074

einstein per square meter per second
notation: einstein/sm2
type: SIO_000074

2-hydroxyphenanthrene
type: Class
subclass of: PAH
notation: PHEN2

Electron Capture Dissociation (ECD)
type: Class
subclass of: TandemMassSpectrometry

microvolt
type: SIO_000074
notation: µV

Enzyme Immunoassay
subclass of: Immunoassay
type: Class

mono (2-ethyl-5-hydroxyhexyl) phthalate
type: Class
notation: MEHHP
subclass of: Phthalate

Analyte
type: Class
subclass of: SIO_010004

1-hydroxychrysene
notation: CHRY1
subclass of: PAH
type: Class

HUC sample having discrepancy between fluorometer results and semi quantative Albustix test results
type: Class
subclass of: SIO_001167

mono(7-carboxyheptyl)phthalate
notation: mCHpP
subclass of: Phthalate
type: Class

square meter
type: SIO_000074
notation: m2

Mirex
subclass of: Organochlorine Compound
notation: MIREX
type: Class

Value above LOD but below LLOQ
type: Class
subclass of: SIO_001167

nanogram per milliliter
notation: ng/ml
type: SIO_000074

Zinc
definition: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
notation: Zn
subclass of: Metal
type: Class

parasites per microgram
notation: parasites/µL
type: SIO_000074

Liquid Chromatography - Tandem Mass Spectrometer
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS is the combination of two mass analyzers in one mass spec instrument.
subclass of: Tandem Mass Spectrometer
was approved by: chear-kb:PER-Jim-McCusker
type: Class
subclass of: Liquid Chromatography–Mass Spectrometer

Fenton Preterm Growth Chart
subclass of: SIO_000442
definition: A growth chart adusted for gestational age
type: Class

Non-Biological Relative
definition: People that are considered relatives but are not related by blood. This includes relatives by marriage, adoption, or fosterage.
type: Class
subclass of: Relative

Below LOD, results repeated and confirmed (37, 33)
type: Class
subclass of: SIO_001167

mono benzyl phthalate (BzBP)
type: Class
subclass of: Phthalate
notation: MBP

micron pixel
type: SIO_000074
notation: µm pixel

PFC
subclass of: Targeted Analyte
type: Class

Interleukin-15
notation: IL15
subclass of: SIO_010043
type: Class

3-methipurc acd, 4-methipurc acd(ng/mL)
notation: VOC34M
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

parts per million
type: SIO_000074
notation: ppm

microgram
notation: µg
type: SIO_000074

HOMA-IR
type: SIO_000074
notation: (mg/dL)*(µU/mL)

gram per deciliter
notation: g/dl
type: SIO_000074

joule
type: SIO_000074
notation: J

Benzophenone-1
type: Class
notation: BP1
subclass of: Benzophenone

milliunits per milliliter
notation: mU/ml
type: SIO_000074

Cell
subclass of: Biospecimen
type: Class

3-hydroxychrysene
subclass of: PAH
type: Class
notation: CHRY3

2-hydroxybenzo[c]-phenanthrene
notation: BCP2
type: Class
subclass of: PAH

nanosievert
notation: nSv
type: SIO_000074

femtoliter
type: SIO_000074
notation: fl

Saliva
subclass of: Bodily Fluid
definition: A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. [database_cross_reference: http://en.wikipedia.org/wiki/Saliva][database_cross_reference: GO:0046541]
type: Class

micrograms per meter cubed
type: SIO_000074
notation: µg/m3

Daughter
subclass of: Restriction
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010052
  on property: isRoleOf
definition: The female offspring in relation to her parents.
subclass of: Child
type: Class

base pair
type: SIO_000074
notation: bp

Infrared Multiphoton Dissociation (IRMPD)
subclass of: TandemMassSpectrometry
type: Class

monooxoisononyl phthalate (DiNP)
notation: MONP

Creatinine
type: Class
definition: Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
notation: CRE
subclass of: Targeted Analyte

milligram per liter
type: SIO_000074
notation: mg/L

C-reactive protein
type: Class
definition: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
subclass of: SIO_010043
subclass of: Biological Response

unit per liter
type: SIO_000074
notation: U/l

Femur
subclass of: SIO_010046
type: Class

enzyme unit
notation: enzyme unit
type: SIO_000074

Ruthenium
subclass of: Metal
definition: RUTHENIUM is a hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.
notation: Ru
type: Class

Trans-Chlordane
subclass of: Organochlorine Compound
notation: TCHL
type: Class

picomolar
notation: pM
type: SIO_000074

Agilent 1100 HPLC
was approved by: chear-kb:PER-Jim-McCusker
subclass of: High-Performance Liquid Chromatography
type: Class

Polybrominated Diphenyl Ether
type: Class
subclass of: Targeted Analyte

Small clot present
subclass of: SIO_001167
type: Class

esophageal disease
type: Class
subclass of: SIO_010299

megavolt
type: SIO_000074
notation: MV

Organochlorine Compound
subclass of: Targeted Analyte
type: Class

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2PHEN3

microsecond
notation: µs
type: SIO_000074

Medical Therapy Procedure
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_001024
subclass of: Medical History
definition: Medical Therapy Procedure to aide in treatment.
type: Class
type: QualityVariable

Fast Food Consumption Frequency
type: QuantityVariable
definition: Frequency of Fast Food Consumption.
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Diet Quantity

3-Hydroxypropyl-1-methyl mercapturic acid + 3-Hydroxypropyl-2-methyl mercapturic acid + 3-Hydroxypropyl-3-methyl mercapturic acid
notation: HMPMA

Infinium Methylation EPIC BeadChip Assay
subclass of: Methylation Assay
type: Class
subclass of: Microarray Assay

milliliter per kilogram
type: SIO_000074
notation: ml/kg

microgram per gram
type: SIO_000074
notation: ug/g

hexadecanoic acid
definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
type: Class
subclass of: Fatty Acid
notation: C160

Roentgen equivalent man
type: SIO_000074
notation: rem

Interfering substances present
subclass of: SIO_001167
type: Class

millimetres of mercury
type: SIO_000074
notation: mmHg

gram per liter
notation: g/L
type: SIO_000074

Sleep Characterisitic
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Sleep Characterisitics Indicator Class
type: Class

Copper
notation: Cu
type: Class
definition: COPPER is a heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
subclass of: Metal

Methyl Paraben
definition: Methylparaben is a Standardized Chemical Allergen. The physiologic effect of methylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of methylparaben is Allergens.
subclass of: Paraben
notation: MePB
type: Class

dyne per cm
type: SIO_000074
notation: dyn/cm

Alcohol, Tobacco, and Illicit Drug Use
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Alcohol, Tobacco, and Illicit Drug Use Indicator Class
type: Class

hematocrit
type: Class
subclass of: SIO_001018

Phenanthrene tetrol
notation: PHET

Washing Machine Count
subclass of: Household Appliance Count
type: Class
was approved by: chear-kb:PER-Jeanette-Stingone
type: QuantityVariable
definition: Number of machines used for washing clothes in the home.

Tissue
type: Class
subclass of: Biospecimen

katal
type: SIO_000074
notation: kat

mole
type: SIO_000074
notation: mol

Abnormal hemoglobin variant observed
subclass of: SIO_001167
type: Class

Competitive Immunoassay
subclass of: Immunoassay
type: Class

2, 2', 4, 4', 6-Pentabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE100
type: Class
subclass of: Polybrominated Diphenyl Ether

watt-hour
notation: Wh
type: SIO_000074

Detectable
type: Class
subclass of: SIO_001167

Triclosan
definition: Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
notation: TCS
subclass of: Environmental Phenol
type: Class

Result reported based on fewer replicates than required
type: Class
subclass of: SIO_001167

weber
type: SIO_000074
notation: Wb

nanomole
type: SIO_000074
notation: nmol

mono (3-carboxypropyl) phthalate (multiple)
type: Class
notation: MCPP
subclass of: Phthalate

Behavioral Experimental Paradigm Condition
type: Class
subclass of: Neurocognitive Assessment

4-Hydroxybenzoic acid
notation: HB4
subclass of: Environmental Phenol
type: Class

millivolt
type: SIO_000074
notation: mV

Liquid Chromotography-Mass Spectrometery
type: Class
subclass of: MassSpectrometry

Perfluoro-n-pentanoic acid
type: Class
notation: PFPeA
subclass of: PFC

2, 2'-bis(4-hydroxyphenyl)butane
notation: BPB

mass percentage
notation: w/w
type: SIO_000074

Mercapturic acids of 1, 3-butadiene
type: Class
subclass of: Tobacco Metabolite
notation: HEMA

Apgar Score
type: QuantityVariable
subclass of: SIO_001112
subclass of: Birth Outcome
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: Restriction
  all values from: Datatype
    intersection of: Datatype
      with restrictions:
        min inclusive: 0
      on datatype: integer
    intersection of: Datatype
      on datatype: integer
      with restrictions:
        max inclusive: 10
  on property: hasValue
type: Class
definition: A method to quickly summarize the health of newborn children. The Apgar score was invented by Virginia Apgar in 1952 when Apgar was an anesthesiologist who developed the score in order to ascertain the effects of obstetric anesthesia on babies. The Apgar scale is determined by evaluating the newborn baby on five simple criteria on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10. The five criteria are summarized using words chosen to form a backronym (Appearance, Pulse, Grimace, Activity, Respiration).

foot candle
notation: ft-c
type: SIO_000074

dalton
notation: Da
type: SIO_000074

plaque forming unit per milliliter
type: SIO_000074
notation: pfu/ml

Partial match
subclass of: SIO_001167
type: Class

Polychlorobiphenyl
type: Class
subclass of: Organochlorine Compound

roentgen
type: SIO_000074
notation: Roentgen

nanosecond
notation: ns
type: SIO_000074

micrograms per deciliter
type: SIO_000074
notation: µg/dl

Cyclohexane-1, 2-dicarboxylic acid mono hydroxyisononyl ester (DINCH)
notation: MHNCH

Process
type: Class
subclass of: ScienceIndicator

microliter per kilogram
notation: µl/kg
type: SIO_000074

Subject
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Study
was approved by: chear-kb:PER-Jeanette-Stingone
subclass of: SIO_000016
definition: A living individual about whom a research investigator (whether a professional or a student) obtains data through 1) intervention or interaction with the individual, or 2) identifiable private information

compound eye retinal cell
type: Class
subclass of: Cell

Electron-Detachment Dissociation (EDD)
subclass of: TandemMassSpectrometry
type: Class

mono-2-ethyl-5- carboxypentyl terephthalate (DEHTP)
notation: MECPTP

Interleukin-23 subunit alpha
subclass of: SIO_010043
notation: IL23
type: Class

kilobyte
type: SIO_000074
notation: kB

UBERON_0036255
deprecated: true

siemens
notation: 1/AV
type: SIO_000074

Pregnancy Cohort Study
type: Class
subclass of: CohortStudy

microgray
notation: µGy
type: SIO_000074

milliliter per liter
type: SIO_000074
notation: ml/l

kibibyte
type: SIO_000074
notation: KiB

Specimen analyzed with less than normal quantity
subclass of: SIO_001167
type: Class

4, 4'-cyclo-hexylidenebisphenol
notation: BPZ

eosinophilic esophagitis
subclass of: esophageal disease
type: Class

SO_0000000
deprecated: true

millimolar
type: SIO_000074
notation: mM

Perfluorooctanoic acid
subclass of: PFC
notation: PFOA
type: Class

SIO_000751
notation: 133
type: QualityValue

2, 2'-dihydroxy-methoxybenzophenone
notation: BP8

mono-(2-ethylhexyl) terephthalate
notation: MEHTP

Markedly hemolyzed
subclass of: SIO_001167
type: Class

Pathogen Transmission
subclass of: Process

Nulliparous
notation: 62
type: QualityValue
type: Class
subclass of: Parity

GO_0016265
deprecated: true

Datatype
with restrictions:
  max exclusive: 18.5
on datatype: float

max exclusive: 25.0

min exclusive: 25

Restriction
all values from: Datatype
  on datatype: integer
  with restrictions:
    max exclusive: 15
on property: hasValue

first:
  min exclusive: 29.9
rest: nil

Datatype
intersection of: Datatype
  with restrictions:
    min exclusive: 18.5
  on datatype: float
intersection of: Datatype
  with restrictions:
    max exclusive: 25.0
  on datatype: float

first:
  max exclusive: 25
rest: nil

Datatype
with restrictions:
  min exclusive: 25.0
on datatype: float

Datatype
with restrictions:
  min inclusive: 15
on datatype: integer

Datatype
on datatype: float
with restrictions:
  max exclusive: 29.9

Datatype
with restrictions:
  min exclusive: 25.0
on datatype: float