Perfluorooctanoic acid
type: Class
subclass of: PFC
notation: PFOA

Plutonium
type: Class
notation: Pu
subclass of: Metal
definition: Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.

Liquid Chromatography–Mass Spectrometer
definition: An analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin.
subclass of: Liquid Chromatography Instrument
subclass of: Mass Spectrometer
type: Class
was approved by: PER-Jim-McCusker

Physical and Mental Assessment
was approved by: PER-Jeanette-Stingone
definition: Physical and Mental Assessments Indicator Class
type: Class
subclass of: StudyIndicator

Fresh Vegetable Consumption
definition: Whether or not Fresh Vegetables are consumed.
notation: 29
type: QualityValue
type: Class
subclass of: Fresh Vegetable Consumption Frequency
was approved by: PER-Jeanette-Stingone

Reichert AR200 Handheld Digital Refractometer
was approved by: PER-Jim-McCusker
definition: Lightweight digital refractometer designed for the food, beverage, agricultural, industrial-fluid, chemical, petrochemical, pharmaceutical, medical, and plastic industries.
type: Class
subclass of: Refractometer

Benzo[a]pyrene tetraol
type: Class
subclass of: PAH
notation: BAPT

microgray
type: SIO_000074
notation: µGy

Repeat Caesarian Section
type: Class
subclass of: Caesarian Section
definition: Had Repeat Caesarian Section
type: QualityValue
notation: 21

N-A-S-(3-hydrxprpl-1-metl)-L-cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCPMM
subclass of: Volatile Organic Compound

Lithium
subclass of: Metal
notation: Li
definition: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
type: Class

PCB28
type: Class
subclass of: Polychlorobiphenyl
notation: PCB28

radian
notation: rad
type: SIO_000074

nanosecond
notation: ns
type: SIO_000074

Ultra Performance Liquid Chromatography - Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class
subclass of: Mass Spectrometer
subclass of: Ultra High Performance Liquid Chromatography Instrument

nanogram per milliliter
type: SIO_000074
notation: ng/ml

Freeze/Thaw Cycles Count
was approved by: PER-Jeanette-Stingone
definition: Number of Freeze/Thaw cycles.
type: Class
subclass of: SIO_000794
type: QuantityVariable

(9Z)-hexadecenoic acid
definition: A hexadecenoic acid with a cis-double bond at position C-9.
type: Class
subclass of: Fatty Acid
notation: C161N7

Gas Chromatographer–Mass Spectrometer
subclass of: Gas Chromatography Instrument
subclass of: Mass Spectrometer
type: Class
was approved by: PER-Jim-McCusker
definition: Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples, including that of material samples obtained from planet Mars during probe missions as early as the 1970s. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification. Like liquid chromatography–mass spectrometry, it allows analysis and detection even of tiny amounts of a substance.

t, t-Muconic acid(ng/mL)
type: Class
notation: VOCMUC
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

Boron
definition: A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY.
notation: B
subclass of: Metal
type: Class

Adult
type: QualityValue
type: Class
definition: Refers to a person above a threshold age.
notation: 3
subclass of: Developmental Quality
subclass of: Demographic
was approved by: PER-Jeanette-Stingone

No Sickle Cell Anemia
notation: 138
type: QualityValue
subclass of: Medical History
type: Class

Specific Gravity
editorial note: Why is this here? Maybe it belongs in another list
subclass of: SIO_001018
type: QuantityVariable
definition: Specific gravity is the ratio of the density of a substance to the density of a reference substance; equivalently, it is the ratio of the mass of a substance to the mass of a reference substance for the same given volume. Apparent specific gravity is the ratio of the weight of a volume of the substance to the weight of an equal volume of the reference substance. The reference substance is nearly always water at its densest (4°C) for liquids; for gases it is air at room temperature (21°C). Nonetheless, the temperature and pressure must be specified for both the sample and the reference. Pressure is nearly always 1 atm (101.325 kPa). Temperatures for both sample and reference vary from industry to industry.
subclass of: Targeted Analyte
type: Class

N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
subclass of: Volatile Organic Compound
notation: MHBMA2
type: Class
editorial note: To Do: align with CHEBI.

Active Smoker
type: Class
editorial note: How is this different from "smoker'?
definition: The quality of actively smoking.
notation: 2
subclass of: Smoking Status
type: QualityValue

3-phenoxybenzoic acid
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
notation: PBA
type: Class

9-hydroxyfluorene
type: Class
subclass of: PAH
notation: FLUO9

Fenton Preterm Growth Chart
definition: A growth chart adusted for gestational age
type: Class
subclass of: SIO_000442

weber
notation: Wb
type: SIO_000074

2-Thioxothiazolidine-4-carboxylic acid
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class
notation: TTCA

monoisononyl phthalate
notation: MIP
type: Class
editorial note: Duplicate of mINP?
subclass of: Phthalate

Screening
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
definition: The time period during which a screening process is used to determine the inclusion of a subject in a study.
type: Class

Consumed Alcohol
type: QualityValue
subclass of: Alcohol Use
type: Class
notation: 52

Pre-Pregnancy
definition: The time before a pregnancy.
type: Class
subclass of: From Conception
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo

Religion
type: QualityVariable
definition: Religious Belief
subclass of: Demographic
type: Class

Height
type: QuantityVariable
type: Class
subclass of: Anthropometry
definition: Height
was approved by: PER-Jeanette-Stingone

2, 3', 4, 4'-Tetrabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE66
editorial note: To Do: align with CHEBI.
type: Class

PCB180
subclass of: Polychlorobiphenyl
type: Class
notation: PCB180

Antimony
subclass of: Metal
type: Class
notation: Sb
definition: ANTIMONY is a metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.

Value below LLOQ, no LOD provided
subclass of: SIO_001167
type: Class

Pregnancy
subclass of: Pregnancy Characteristic
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
subclass of: From Conception
was approved by: PER-Jeanette-Stingone
definition: The time during which one or more offspring develops inside a woman.

volt per meter
notation: V/m
type: SIO_000074

Gravimetric Analysis Instrument
definition: Gravimetric analysis describes a set of methods used in analytical chemistry for the quantitative determination of an analyte (the ion being analyzed) based on its mass. The principle behind this type of analysis is that once an ion's mass has been determined as a unique compound, that known measurement can then be used to determine the same analyte's mass in a mixture, as long as the relative quantities of the other constituents are known.
was approved by: PER-Jim-McCusker
type: Class
subclass of: PhysicalInstrument

Technical School
subclass of: Education
was approved by: PER-Jeanette-Stingone
notation: 96
type: QualityValue
definition: Attended a Technical School.
type: Class

Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometer
type: Class
subclass of: Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
subclass of: Ultra Performance Liquid Chromatography - Mass Spectrometer

Iodine
notation: I
subclass of: Element
type: Class
definition: Iodine is a nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.

3-Hydroxypropyl-1-methyl mercapturic acid + 3-Hydroxypropyl-2-methyl mercapturic acid + 3-Hydroxypropyl-3-methyl mercapturic acid
notation: HMPMA

Cord Blood
subclass of: Whole Blood
type: Class
subclass of: Pregnancy Sample
definition: Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Cord_blood]

Birth Outcome
was approved by: PER-Jeanette-Stingone
type: Class
editorial note: • [WARNING] SDD_00013: The Dictionary Mapping has the following cells with missing labels: cmo:0001297 .
definition: Birth Outcomes Indicator Class
subclass of: StudyIndicator

meter
type: SIO_000074
notation: m

mono-benzyl phthalate
editorial note: Is this a repeat of MBP?
type: Class
subclass of: Phthalate
notation: mBzP

Developmental Quality
subclass of: SIO_000475
was approved by: PER-Jeanette-Stingone
definition: Refers to which stage of development a person is in.
type: Class
type: QualityVariable

Antimalarial
definition: A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
type: QualityValue
subclass of: Medication
type: Class
notation: 120

Prescription Medication and Dietary Supplements
definition: Prescription Medication and Dietary Supplements are forms of medical treatment.
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: StudyIndicator

molal
notation: mol/kg
type: SIO_000074

Absorbance Reader
subclass of: Microplate Reader
was approved by: PER-Jim-McCusker
definition: Absorbance readers are used for assays such as ELISA assays, protein and nucleic acid quantification or enzyme activity assays. A light source illuminates the sample using a specific wavelength (selected by an optical filter, or a monochromator), and a light detector located on the other side of the well measures how much of the initial (100%) light is transmitted through the sample: the amount of transmitted light will typically be related to the concentration of the molecule of interest.
type: Class

Process
subclass of: ScienceIndicator
type: Class

C-reactive protein
definition: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
subclass of: SIO_010043
type: Class
subclass of: Biological Response

American Indian Or AlaskanNative
type: QualityValue
subclass of: Race
notation: 5
type: Class
definition: A person having origins in any of the original peoples of North and South America (including Central America) and who maintains tribal affiliation or community attachment.
was approved by: PER-Jeanette-Stingone

Mono-n-pentyl phthalate
subclass of: Phthalate
editorial note: Duplicate of mPeP?
type: Class
notation: MPP

Specimen analyzed with less than normal quantity
type: Class
subclass of: SIO_001167

Styrene
notation: STY
type: Class
definition: STYRENE is a colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.
subclass of: Volatile Organic Compound

Serum
subclass of: Blood Component
type: Class
definition: Liquid derived from blood plasma that has clotting factors removed. [database_cross_reference: http://en.wikipedia.org/wiki/Serum_(blood)][database_cross_reference: http://orcid.org/0000-0002-6601-2165]

Exposure Monitoring Instrument
definition: A physical instrument that monitors the environment for chemical exposures.
type: Class
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker

Beryllium
definition: Beryllium. An element with the atomic symbol Be, atomic number 4, and atomic weight 9.01218. Short exposure to this element can lead to a type of poisoning known as BERYLLIOSIS.
notation: Be
type: Class
subclass of: Metal

Medical Therapy Procedure
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Medical History
subclass of: SIO_001024
type: QualityVariable
definition: Medical Therapy Procedure to aide in treatment.

Weight
subclass of: SIO_000279
type: QuantityVariable
definition: The resulting Force from the interaction between a person's Mass and Gravity.
subclass of: Anthropometry
was approved by: PER-Jeanette-Stingone
type: Class

N-Acetyl-S-(n-propyl)-L-cysteine(ng/mL)
subclass of: Volatile Organic Compound
type: Class
notation: VOCBPM
editorial note: To Do: align with CHEBI.

Computer
type: QuantityVariable
definition: A machine used for computation and much more.
subclass of: Household Appliance Count
type: Class
was approved by: PER-Jeanette-Stingone

Analysis
subclass of: Analyte
type: Class
definition: The value contains concentrations from the study sample

2, 4, 5-Trichlorophenol
definition: Exposure to 2, 4, 5-trichlorophenol may occur during its production or use as a pesticide. Acute (short-term) dermal exposure to 2, 4, 5-trichlorophenol may burn skin in humans. It also irritates the eyes, nose, pharynx, and lungs in humans. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of 2, 4, 5-trichlorophenol in humans. In one study, slight degenerative changes were observed in the liver and kidneys of rats chronically exposed to 2, 4, 5-trichlorophenol in their diet. EPA has classified 2, 4, 5-trichlorophenol as a Group D, not classifiable as to human carcinogenicity. PHYSICAL DESCRIPTION: Colorless needles, gray flakes or off-white lumpy solid. Phenolic odor. Formerly used as a fungicide and bactericide.
type: Class
notation: TCP245
subclass of: Environmental Phenol

trans, trans -Muconic acid
type: Class
notation: MU
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

N-Ace-S-(dimethylphenyl)-L-Cys(ng/mL)
notation: VOCDPM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

colony forming unit per milliliter
notation: cfu/ml
type: SIO_000074

Homemaker
definition: A person who manages a home as their main daily activity.
subclass of: Occupation
type: QualityValue
type: Class
notation: 68

Dental Fillings
type: QualityValue
notation: 13
type: Class
subclass of: Oral Health

Interleukin-33
label: 72 kDa type IV collagenase
type: Class
notation: MMP2
notation: IL33
subclass of: SIO_010043

kibibyte
notation: KiB
type: SIO_000074

4, 4'-(1-phenylethylidene)bisphenol
notation: BPAP

Gel Electrophoresis
subclass of: SIO_001007
definition: Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.
type: Class

Ever Smoked
type: QualityValue
notation: 136
definition: The quality of having smoking in the past.
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Smoking Status

Education
subclass of: SIO_000026
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: QualityVariable
definition: The act or process of imparting or acquiring knowledge.
type: Class
subclass of: Socioeconomic Status

Mass Spectrometer
type: Class
subclass of: PhysicalInstrument
definition: Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio. In simpler terms, a mass spectrum measures the masses within a sample. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures.
was approved by: PER-Jim-McCusker

Increased Body Weight
subclass of: Body Weight Quality
type: QualityValue
definition: BMI > 25
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
type: Class
notation: 72

Niobium
subclass of: Metal
notation: Nb
type: Class
definition: Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)

Gestational Age at Birth
equivalent class: Class
  intersection of: Gestational Age
  intersection of: Restriction
    on property: measuredAt
    all values from: Birth
definition: Describes how far along a pregnancy is, usually measured in weeks, as measured at birth.
type: Class
subclass of: Gestational Age

Competitive Immunoassay
subclass of: Immunoassay
type: Class

Normal Weight
subclass of: Body Weight Quality
subclass of: Underweight/Normal
definition: 18.5<=BMI<=25
notation: 61
type: Class
type: QualityValue
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129

Red Blood Cell
subclass of: Blood Component
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
type: Class

Z-Score
definition: A z-score (also known as z-value, standard score, or normal score) is a measure of the divergence of an individual experimental result from the most probable result, the mean. Z is expressed in terms of the number of standard deviations from the mean value.
subclass of: Anthropometry
type: Class

Laboratory Result
subclass of: SampleIndicator
definition: A measurement taken on a sample.
type: Class

4, 4'-DDE
subclass of: Organochlorine Compound
notation: PPDDE
type: Class

Environmental Exposure
type: Class
was approved by: PER-Jeanette-Stingone
editorial note: may need to refine this name in order to clearly differentiate from environmental exposures measured within CHEAR. Perhaps ExternalEnvironmental Exposure. Ok for now but we may want to discuss.
subclass of: StudyIndicator
definition: EnvironmentalExposure Indicator Class

Inductively Coupled Plasma Mass Spectrometer
definition: A type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 10^15 (part per quadrillion, ppq) on non-interfered low-background isotopes. This is achieved by ionizing the sample with inductively coupled plasma and then using a mass spectrometer to separate and quantify those ions.
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker

High Performance Liquid Chromatography - Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS (Tandem MS) is the combination of two mass analyzers in one mass spec instrument.
subclass of: High-Performance Liquid Chromatography-Mass Spectrometry
subclass of: Liquid Chromatography - Tandem Mass Spectrometer
type: Class

formazin nephelometric unit
notation: FNU
type: SIO_000074

Sandwich ELISA
type: Class
definition: Sandwich ELISAs involve attachment of a capture antibody to a solid phase support. Samples containing known or unknown antigen are then added in a matrix or buffer that will minimize attachment to the solid phase. An enzyme-labeled antibody is then added for detection.
subclass of: enzyme-linked immunosorbent assay (ELISA)

Blood Component
definition: A derivable component of whole blood.
subclass of: Bodily Fluid
type: Class

cubic meter per kilogram
type: SIO_000074
notation: m3/kg

Maternal Weight Gain
was approved by: PER-Jeanette-Stingone
type: Class
definition: The amount of weight gained during a pregnacy.
subclass of: Pregnancy Characteristic
subclass of: Weight

1, 2-Dichloroethane
definition: Ethylene Dichloride is a clear, colorless, oily, synthetic, flammable liquid chlorinated hydrocarbon with a pleasant chloroform-like smell that emits toxic fumes of hydrochloric acid when heated to decomposition. Ethylene dichloride is primarily used to produce vinyl chloride. Inhalation exposure to this substance induces respiratory distress, nausea and vomiting and affects the central nervous system, liver and kidneys. It is mutagenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05)
subclass of: Volatile Organic Compound
type: Class
notation: DE12

Diet Quantity
type: Class
type: QuantityVariable
subclass of: SIO_000052
editorial note: What differentiated diet from nutrition? That is why is this needed since we have the DietAndNutrition Class
subclass of: Diet and Nutrition
definition: A quantity relating to diet and nutrition.
was approved by: PER-Jeanette-Stingone

High-Performance Liquid Chromatography
type: Class
subclass of: Liquid Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.

Other GI Disease
subclass of: SIO_010299
type: Class
type: QualityValue
subclass of: Medical History
editorial note: This is a temp concept that needs addressing
notation: 69

kilodalton
type: SIO_000074
notation: kDa

Trimethylarsine oxide
notation: Trimethylarsine oxide
subclass of: Arsenic Species
type: Class

Competitive-inhibition enzyme-linked immunosorbent assay
type: Class
subclass of: enzyme-linked immunosorbent assay (ELISA)

second
notation: s
type: SIO_000074

Refractometer
subclass of: PhysicalInstrument
definition: A laboratory or field device for the measurement of an index of refraction (refractometry). The index of refraction is calculated from Snell's law while for mixtures, the index of refraction can be calculated from the composition of the material using several mixing rules such as the Gladstone–Dale relation and Lorentz–Lorenz equation.
was approved by: PER-Jim-McCusker
type: Class

Colorimetric Assay
type: Class
subclass of: SIO_001007

Cotinine
type: Class
definition: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
notation: COT
subclass of: Tobacco Metabolite

gram
type: SIO_000074
notation: g

Methylation Assay
subclass of: SIO_001007
type: Class
definition: An assay that measures the methylation levels of sections of a genome.

Clinical Measurement
definition: A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation.
subclass of: Physical and Mental Assessment
type: Class

oleic acid
subclass of: Fatty Acid
type: Class
notation: C181N9
definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.

Interleukin-6
notation: IL6
definition: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
subclass of: Biological Response
subclass of: SIO_010043
type: Class

HUC sample having discrepancy between fluorometer results and semi quantative Albustix test results
subclass of: SIO_001167
type: Class

Methyl mercury (CH3Hg+)
subclass of: Mercury Species
type: Class
notation: CH3Hg

N-Acetyl-S- (3, 4-dihydroxybutyl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: DHBMA

Mitest not capped
subclass of: SIO_001167
type: Class

Atomic Spectroscopy
subclass of: Spectroscopy
type: Class

katal
type: SIO_000074
notation: kat

eosinophils per high-power field
subclass of: SIO_000794
type: Class
comment: A histological count of the eosinophils in a high-power microscopic field of view, or 0.158 mm^2 (x400).

milliliter per kilogram
notation: ml/kg
type: SIO_000074

Oral Health
subclass of: StudyIndicator
definition: Oral Health Indicator Class
was approved by: PER-Jeanette-Stingone
type: Class

Cotinine (total)
type: Class
notation: COTT
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
type: Class
definition: A tandem mass spectrometer consisting of two quadrupole mass analyzers in series, with a (non-mass-resolving) radio frequency (RF)–only quadrupole between them to act as a cell for collision-induced dissociation.
was approved by: PER-Jim-McCusker
subclass of: Inductively Coupled Plasma Mass Spectrometer

Ethnicity
type: QualityVariable
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000475
subclass of: Demographic
type: Class

Urine
subclass of: Bodily Fluid
type: Class
definition: Excretion that is the output of a kidney [database_cross_reference: http://en.wikipedia.org/wiki/Urine][database_cross_reference: https://github.com/geneontology/go-ontology/issues/11025]

Part Time Employment
definition: Employment involving less than the standard or customary working time.
type: Class
notation: 65
type: QualityValue
subclass of: Occupation

Attribute
type: Class
subclass of: ScienceIndicator

Occupation
subclass of: Demographic
subclass of: Socioeconomic Status
subclass of: SIO_000016
definition: An individual attribute that is the usual or principal work or business of an individual.
type: Class
was approved by: PER-Jeanette-Stingone
type: QualityVariable

Vitamin D
subclass of: Diet and Nutrition
subclass of: Biomolecule
type: Class
definition: Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body.

First Trimester
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
definition: From pregnancy week 1 through 12 and includes conception. Conception is when the sperm fertilizes the egg. The fertilized egg then travels down the fallopian tube and attaches to the inside of the uterus, where it begins to form the embryo and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus).
subclass of: From Conception
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
type: Class

Molybdenum
notation: Mo
subclass of: Metal
type: Class
definition: MOLYBDENUM is a metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)

Soil Floor
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Floor Type
type: Class
definition: The flooring is made of soil.
notation: 84

parts per trillion
type: SIO_000074
notation: ppt

Bathroom Count
was approved by: PER-Jeanette-Stingone
type: Class
definition: Total Number of Bathrooms in the Home
subclass of: Room Count
type: QuantityVariable

Arsenic
subclass of: Metal
type: Class
definition: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
notation: As

Lipemic
subclass of: SIO_001167
type: Class

Physical Activity and Fitness
type: Class
subclass of: StudyIndicator
definition: Physical Activity and Fitness Indicator Class
was approved by: PER-Jeanette-Stingone

cell in vitro
subclass of: Cell
type: Class

mono-2-ethyl-5-hydroxyhexyl terephthalate (DEHTP)
notation: MEHHTP

Step
subclass of: Non-Biological Relative
definition: A stepfamily is a family where at least one parent has children that are not genetically related to the other spouse or partner. Either one parent may have children from a previous relationship. Children in a stepfamily may live with one biological parent, or they may live with each biological parent for a period of time. In addition, visitation rights mean that children in stepfamilies often have contact with both biological parents, even if they permanently live with only one. A child is referred to as the stepchild, stepdaughter or stepson of their biological parent's new spouse, and that person as the stepparent, stepfather or stepmother of the child. A stepfather is the husband of one's mother, and not one's biological father. A stepmother is the wife of one's father, and not one's biological mother. A step-grandmother is the wife of one's grandfather, and not one's biological grandmother. A step-grandfather is the husband of one's grandmother, and not one's biological grandfather. Similarly, a stepbrother is the son of a stepparent who one is not biologically related to. A stepsister is the daughter of a stepparent to whom one is not biologically related. A step-grandson is the son of a stepson or stepdaughter who one is not biologically related to. A step-granddaughter is the daughter of a stepson or stepdaughter who one is not biologically related. A parent's spouse of the same sex may also count as a stepparent.
type: Class

cells per microliter
type: SIO_000074
notation: cp/µl

N-Ace-S-(2-carbamoylethyl)-L-cys(ng/mL)
notation: VOCAAM
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

Perfluroundecanoic acid
notation: PFUNDA
type: Class
subclass of: PFC

HHEAR
imports: cmo.owl
imports: stato.owl
version IRI: http://purl.org/twc/HHEAR/1.1
type: Ontology
imports: cl-basic.owl
imports: sio.owl
imports: uo.owl
imports: prov
comment: The Human Health Exposure Analysis Resource (HHEAR) measures exposures that cover the breadth of the “exposome,” which encompasses all environmental exposures including chemical, physical, and biological stressors, as well as lifestyle and social environments, from conception through adulthood. Read more at: https://hhearprogram.org
imports: cogat

Some Elementary School
was approved by: PER-Jeanette-Stingone
type: Class
definition: Attended Some Elementary School
notation: 86
type: QualityValue
subclass of: High School or Less

Environmental Material
subclass of: SIO_010412
type: Class
subclass of: SampleIndicator

Quit Smoking
definition: Quit Smoking Cigarettes
type: Class
type: QualityValue
notation: 82
subclass of: Previous Smoker

Non-Hispanic Ethnicity
type: QualityValue
notation: 58
definition: Non-Hispanic Ethnicity
subclass of: Ethnicity
was approved by: PER-Jeanette-Stingone
type: Class

neuron
subclass of: Cell
type: Class

milligram
notation: mg
type: SIO_000074

N-Acetyl-S-(phenyl)-L-cysteine(ng/mL)
subclass of: Volatile Organic Compound
type: Class
notation: VOCPMA
editorial note: To Do: align with CHEBI.

Feces
subclass of: Biospecimen
definition: Portion of semisolid bodily waste discharged through the anus[MW, modified] [database_cross_reference: http://en.wikipedia.org/wiki/Feces][database_cross_reference: http://www.merriam-webster.com/dictionary/feces]
type: Class

megabyte
type: SIO_000074
notation: MB

Prenatal Nonsmoker
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
type: QualityValue
notation: 76
subclass of: Non-smoker
type: Class
definition: Could be a former smoker or a non-smoker, so neither should be encoded as the superclass.

2, 4, 4'-Tribromodiphenyl ether
type: Class
notation: BDE28
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.

Atomic Emission Spectroscopy
type: Class
subclass of: Atomic Spectroscopy

micromole
type: SIO_000074
notation: µmol

Slightly hemolyzed
subclass of: SIO_001167
type: Class

2, 4, 5, 6-Tetrachlorophenol
subclass of: Environmental Phenol
notation: TeCP2456
type: Class
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)

Before
subclass of: Relative Time
definition: A negative index of a time measurement in relation to a reference event. A conventional time measurement can be generated from a before time measurement by duplicating the measurement, reversing the sign of the value, and removing the "Before" class.
type: Class

Butyl paraben
notation: BuPB
definition: Butylparaben is a Standardized Chemical Allergen. The physiologic effect of butylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of butylparaben is Allergens.
subclass of: Paraben
type: Class

Hair
type: Class
definition: A filament, mostly protein, that grows from follicles found in the dermis[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Hair]
subclass of: Tissue

N-Acetyl-S-(trichlorovinyl)-L-cys(ng/mL)
type: Class
notation: VOCTCV
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

Steroid Treatment form of Medical Therapy
was approved by: PER-Jeanette-Stingone
type: QualityValue
type: Class
definition: Had a form of treatment which uses steroids.
subclass of: Medical Therapy Procedure
notation: 28

Vaginal Birth
subclass of: Route Of Delivery
editorial note: Again, can we add a delivery class
subclass of: Pregnancy Characteristic
notation: 24
type: QualityValue
subclass of: SIO_000582
definition: Had a birthing occur via the vagina.
type: Class

4, 4'-cyclo-hexylidenebisphenol
notation: BPZ

SIO_000982
notation: 106
type: QualityValue

adrenic acid
type: Class
notation: C224N6
subclass of: Fatty Acid

picometer
notation: pm
type: SIO_000074

Proton Pump Inhibitor Treatment
type: QualityValue
definition: Proton Pump Inhibitor Treatment as a form of medical therapy.
type: Class
subclass of: Medical Therapy Procedure
editorial note: UPDATE: Yes, add the prescription medication, either as an indicator or as a class under Medical Therapy. Whichever works for the ontology. Why isn't this listed under prescription medication? How do you differentiate between medical therapy and prescription medication?
notation: 27

3-Chlorophenol
subclass of: Environmental Phenol
definition: PHYSICAL DESCRIPTION: White crystals with an odor of phenol. Sinks in and slowly dissolves in water. (NTP, 1992)
type: Class
notation: MCP3

Ethyl mercury (C2H5Hg+)
notation: C2H5Hg
type: Class
subclass of: Mercury Species

watt per square meter
notation: W/m2
type: SIO_000074

Public Insurance
type: Class
subclass of: Insurance
notation: 79
type: QualityValue

Chloroform
subclass of: Volatile Organic Compound
definition: CHLOROFORM is a commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.
notation: CFRM
type: Class

Alcohol, Tobacco, and Illicit Drug Use
type: Class
definition: Alcohol, Tobacco, and Illicit Drug Use Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone

Perfluorohexane-1-sulphonic acid
type: Class
notation: PFHxS
subclass of: PFC

femtogram
type: SIO_000074
notation: fg

o-Xylene
notation: OXY
definition: O-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
subclass of: Volatile Organic Compound
type: Class

milliliter per cubic meter
type: SIO_000074
notation: ml/m3

Arsenocholine
subclass of: Arsenic Species
notation: Arsenocholine
type: Class

beta-hexachlorocyclohexane
subclass of: Organochlorine Compound
type: Class
notation: BHCH

Higher Education
was approved by: PER-Jeanette-Stingone
subclass of: Education
type: QualityValue
definition: College or university education beyond the successful completion of high school or grammar school, or the attainment of an approved equivalent
type: Class
notation: 31

Benzophenone-3
subclass of: Environmental Phenol
type: Class
editorial note: Duplicate of OXB?
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
notation: BP3

Value less than LOD
subclass of: SIO_001167
type: Class

A Sample has a Pairing
definition: Refers to having paired samples.
type: Class
editorial note: This actually should be a process. What should we do?
subclass of: SIO_001049
was approved by: PER-Jeanette-Stingone

Quit Smoking After Pregnancy
definition: Quit Smoking After Pregnancy
subclass of: Pregnancy Characteristic
notation: 80
type: QualityValue
type: Class
subclass of: Quit Smoking
subclass of: Prenatal Smoker

8-isoprostane
subclass of: Biomolecule
subclass of: Biological Response
type: Class

Inductively Coupled Plasma Mass Spectrometry
subclass of: MassSpectrometry
type: Class

2, 2', 3, 4, 4'-Pentabromodiphenyl ether
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
notation: BDE85

Car Count
subclass of: SIO_000794
type: Class
subclass of: Housing Characteristic
type: QuantityVariable
definition: Total Number of Cars in the Home
editorial note: Again, this isn't related to physical properties of housing. This is more closely related to Socioeconomic Status. Consider moving it.

nanoliter
type: SIO_000074
notation: nl

microsievert
notation: µSv
type: SIO_000074

Analyte
type: Class
subclass of: SIO_010004

Mother
type: Class
subclass of: Restriction
  all values from: Restriction
    some values from: SIO_010052
    on property: hasAttribute
  on property: isRoleOf
definition: A mother is the female parent of a child. Mothers are women who inhabit or perform the role of bearing some relation to their children, who may or may not be their biological offspring. Thus, dependent on the context, women can be considered mothers by virtue of having given birth, by raising their child(ren), supplying their ovum for fertilisation, or some combination thereof. Such conditions provide a way of delineating the concept of motherhood, or the state of being a mother. Women who meet the third and first categories usually fall under the terms 'birth mother' or 'biological mother', regardless of whether the individual in question goes on to parent their child. Accordingly, a woman who meets only the second condition may be considered an adoptive mother, and those who meet only the third a surrogacy mother. The above concepts defining the role of mother are neither exhaustive nor universal, as any definition of 'mother' may differ based on how social, cultural, and religious roles are defined.
was approved by: PER-Jeanette-Stingone
subclass of: Parent

Leptin
subclass of: Biological Response
definition: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.
subclass of: Analyte
type: Class
subclass of: SIO_010043

Lead
definition: LEAD is a soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.19, symbol Pb. (Dorland, 28th)
notation: Pb
type: Class
subclass of: Metal

Alcohol Use
definition: Uses Alcohol
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: QualityValue
notation: 83
type: Class

watt per steradian
notation: W/sr
type: SIO_000074

tetracosanoic acid
notation: C240
subclass of: Fatty Acid
definition: A C24 straight-chain saturated fatty acid.
type: Class

Interferon lambda-2
notation: IL28A
type: Class
subclass of: SIO_010043

milliunits per milliliter
type: SIO_000074
notation: mU/ml

Never Smoked
was approved by: PER-Jeanette-Stingone
notation: 56
definition: The quality of never smoking in the past.
type: QualityValue
type: Class
subclass of: Smoking Status

Whole Blood
subclass of: Bodily Fluid
type: Class
definition: A fluid that is composed of blood plasma and erythrocytes. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Blood][database_cross_reference: https://github.com/obophenotype/uberon/issues/9][database_cross_reference: FMA:9670]

kelvin
notation: K
type: SIO_000074

N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine
notation: MHBMA3
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Mercapturic acid of benzene
notation: SPMA
subclass of: PAH
type: Class

Elementary School
notation: 15
was approved by: PER-Jim-McCusker
type: QualityValue
definition: Finished Elementary School
subclass of: Some Elementary School
type: Class

Technical Post Primary School
notation: 95
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical Post Primary School
type: QualityValue
subclass of: Technical School
type: Class
subclass of: High School or Less

Route Of Delivery
type: QualityVariable
subclass of: Delivery Characteristics
type: Class

Silver
notation: Ag
subclass of: Metal
definition: Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
type: Class

Beginning
type: Class
subclass of: Relative Time
subclass of: Restriction
  on property: hasValue
  has value: 1
definition: A time relative to the beginning of an event

hour
notation: h
type: SIO_000074

Mercapturic acids of 1, 3-butadiene
subclass of: Tobacco Metabolite
notation: HEMA
type: Class

Neighborhood Characteristic
was approved by: PER-Jeanette-Stingone
definition: Neighborhood Characteristic Indicator Class
type: Class
subclass of: StudyIndicator

Analysis Mode
definition: Analysis Mode
subclass of: SampleIndicator
type: QualityVariable
type: Class

count per nanomolar second
notation: 1/nMs
type: SIO_000074

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine
notation: HPMA
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class

Haircare Product Use
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Personal Product Use
notation: 30
type: Class

microliters per minute
type: SIO_000074
notation: µL/min

High School or Less
was approved by: PER-Jeanette-Stingone
definition: Education Level of High School or Less
notation: 33
type: QualityValue
type: Class
subclass of: Education

4-Chlorophenol
notation: MCP4
type: Class
subclass of: Environmental Phenol
definition: P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible. Used as an intermediate in organic synthesis of dyes and drugs.

Small Molecule
subclass of: Biomolecule
definition: A small molecule is a low molecular weight (< 900 daltons) organic compound that may help regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
type: Class

N-Acetyl-S-(phenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: PMA
type: Class

Some Middle School
definition: Attended Some Middle School
was approved by: PER-Jeanette-Stingone
notation: 90
type: QualityValue
subclass of: High School or Less
type: Class

Multiracial
was approved by: PER-Jeanette-Stingone
definition: Having ancestors of several or various races.
notation: 54
subclass of: Race
editorial note: Not part of current prov for Race. Should we remove this concept?
type: QualityValue
type: Class

N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: MHBMA1

newton per meter
notation: N/m
type: SIO_000074

2, 2', 4, 4', 5-Pentabromodiphenyl ether
notation: BDE99
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Polybrominated Diphenyl Ether

Replicate
definition: The value contains data for a repeat of the study sample
subclass of: Analyte
type: Class

VCR Player Count
definition: Number of devices that play VCRs in the home.
type: QuantityVariable
subclass of: Household Appliance Count
type: Class
was approved by: PER-Jeanette-Stingone

Graduated From High School
notation: 32
type: Class
subclass of: High School or Less
type: QualityValue
definition: The quality of having graduated from High School
was approved by: PER-Jeanette-Stingone

Biological Response
definition: Indicator of biological response to environmental exposure
type: Class
subclass of: StudyIndicator
editorial note: abolic_SDD_v1.xlsx

percent
notation: %
type: SIO_000074

Childhood
type: QualityValue
was approved by: PER-Jeanette-Stingone
definition: A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence.
subclass of: Demographic
subclass of: Developmental Quality
notation: 11
type: Class

Parent
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Child
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
subclass of: Ancestor
definition: A parent is the caretaker of a child (where "child" refers to offspring, not necessarily age). A biological parent is a person whose gamete resulted in a child, a male through the sperm, and a female through the ovum. Parents are first-degree relatives and have 50% genetic meet. A female can also become a parent through surrogacy. Some parents may be adoptive parents, who nurture and raise an offspring, but are not actually biologically related to the child. Orphans without adoptive parents can be raised by their grandparents or other family members.

radian per second
notation: rad/s
type: SIO_000074

Tin
definition: TIN is a trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
notation: Sn
subclass of: Metal
type: Class

Floor Type
type: QualityVariable
subclass of: SIO_000004
definition: Type of material that makes up the floor.
type: Class
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone

Interleukin-31
notation: IL31
subclass of: SIO_010043
type: Class

Elective Caesarian Section
notation: 19
type: Class
definition: A caesarian section that was chosen by the mother but was not medically necessary.
type: QualityValue
subclass of: Caesarian Section

Interleukin-23 subunit alpha
notation: IL23
type: Class
subclass of: SIO_010043

katal per cubic meter
notation: kat/m3
type: SIO_000074

all-cis-docosa-4, 7, 10, 13, 16, 19-hexaenoic acid
type: Class
definition: A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
notation: C226N3
subclass of: Fatty Acid

Overloaded filter
subclass of: SIO_001167
type: Class

2, 2', 4, 4', 5, 6'-Hexabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE154
subclass of: Polybrominated Diphenyl Ether
type: Class

Long Range Polymerase Chain Reaction
subclass of: Polymerase Chain Reaction
definition: Amplification of DNA lengths that cannot typically be amplified using routine PCR methods or reagents. For simple DNA templates, polymerases optimized for Long Range PCR can amplify up to 30 kb and beyond. For complex, genomic templates, 20 kb is a typical target.
was approved by: PER-Jim-McCusker
type: Class

Gas Chromatographer-Tandem Mass Spectrometer
subclass of: Tandem Mass Spectrometer
type: Class
definition: MS/MS is the combination of two mass analyzers in one mass spec instrument.
was approved by: PER-Jim-McCusker
subclass of: Gas Chromatographer–Mass Spectrometer

Vanadium
definition: A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.
type: Class
notation: V
subclass of: Metal

Acculturation
definition: Acculturation explains the process of cultural change and psychological change that results following meeting between cultures. This metaclass contains all classes that measure this process.
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: StudyIndicator

MicroPEM
was approved by: PER-Jim-McCusker
subclass of: Exposure Monitoring Instrument
definition: The MicroPEM device monitors individual exposures to very fine airborne particles—or particulate matter—at two sizes. PM10 has a diameter of less than 10 micrometers (PM10), which is approximately 1/30th the size of a human hair, and PM2.5, which at diameters of less than 2.5 micrometers, is even smaller.
type: Class

Samples Arrived Thawed and Analyzed
subclass of: SIO_001167
type: Class

Tobacco Smoke Exposure
type: QualityValue
notation: 98
subclass of: Environmental Exposure
type: Class

Intelligence Quotient
was approved by: PER-Jeanette-Stingone
definition: A measure of intelligence
type: QuantityVariable
subclass of: Physical and Mental Assessment
subclass of: SIO_000052
type: Class

Language
type: QualityVariable
type: Class
editorial note: Needs to be rooted in sio
subclass of: Acculturation

2, 2', 4, 4', 5, 5'-Hexabromobiphenyl
notation: PBB153
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Gravida
type: QuantityVariable
definition: Pregnancy Count, regardless of whether pregnancy was carried to Term.
subclass of: SIO_000794
subclass of: Pregnancy Characteristic
type: Class
was approved by: PER-Jeanette-Stingone

Nulliparous
notation: 62
subclass of: Parity
type: QualityValue
type: Class

Anatabine
notation: ANAT
subclass of: Tobacco Metabolite
type: Class

3, 4-Dihydroxy-benzoic acid methyl ester
notation: OHMeP
subclass of: Environmental Phenol
type: Class

mild eosinophilic esophagitis
subclass of: eosinophilic esophagitis
type: Class
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
comment: Eosinophilic esophagitis is mild when a biopsy of the esophagus reveals a count of 15-25 eosinophils per high-power field area, or 0.158 mm^2 (400x).

nanometer
notation: nm
type: SIO_000074

9-hydroxyphenanthrene
type: Class
notation: PHEN9
subclass of: PAH

platelet count
type: Class
subclass of: SIO_000794

Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages. In a tandem mass spectrometer, ions are formed in the ion source and separated by mass-to-charge ratio in the first stage of mass spectrometry (MS1). Ions of a particular mass-to-charge ratio (precursor ions) are selected and fragment ions (product ions) are created by collision-induced dissociation, ion-molecule reaction, photodissociation, or other process. The resulting ions are then separated and detected in a second stage of mass spectrometry (MS2).
subclass of: Mass Spectrometer
type: Class

Phenotype
type: Class
subclass of: Medical History

Fms-related tyrosine kinase 3 ligand
type: Class
subclass of: SIO_010043
notation: FLT3L

Turbid
subclass of: SIO_001167
type: Class

Drug History
notation: 14
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityVariable

Stress
was approved by: PER-Jeanette-Stingone
subclass of: Stress Frequency
type: Class
definition: Whether or not a person gets stressed.
type: QualityValue
notation: 92

kilobasepair
type: SIO_000074
notation: kbp

kilogram per square meter
type: SIO_000074
notation: kg/m2

Spontaneous Preterm Birth
notation: 91
subclass of: Preterm Birth
type: Class
type: QualityValue

Targeted Analyte
subclass of: Analyte
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: A targeted analyte is one that has been selected by the CHEAR program as a prioritized analyte for CHEAR lab hubs to measure.
type: Class

Esophagus
subclass of: SIO_010003
type: Class

2, 4, 6-Trichlorophenol
definition: 2 4 6-Trichlorophenol is a synthetic, colorless crystalline solid that is slightly soluble in water and soluble in organic solvents. It has been used primarily in pesticide formulations and as a wood preservative, although most uses have been cancelled in the US. When heated to decomposition, 2, 4, 6-trichlorophenol emits toxic and corrosive fumes of hydrochloric acid and other toxic gases. Exposure of humans to 2, 4, 6-trichrophenol via inhalation has been reported to cause respiratory effects, altered pulmonary function and pulmonary lesions. It is reasonably anticipated to be a human carcinogen. (NCI05)
subclass of: Environmental Phenol
type: Class
notation: TCP246

SpectraMax Plus 384 Microplate Reader
subclass of: Microplate Reader
type: Class
definition: Get absorbance measurements from 190 to 1000 nm quickly for samples in test tubes, cuvettes, and 96- or 384-well microplates. The SpectraMax® Plus 384 Microplate Reader gives you walk-up convenience for both standard spectrophotometer and microplate reader applications on the same instrument. Monochromator wavelength selection saves you the time and trouble of ever having to change out filters. Typical applications for this powerful reader include DNA and RNA quantification, enzyme kinetic assays, and ELISA based assays. When your project is ready for high throughput, take advantage of StakMax® automated microplate handling compatibility for full robotic integration.
was approved by: PER-Jim-McCusker

international units per litre
notation: IU/L
type: SIO_000074

Peripheral Blood Mononuclear Cell
subclass of: Cell
definition: Any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.
type: Class

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
notation: VOCMB3
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Irregular result, no concentration reported
subclass of: SIO_001167
type: Class

Caesarian Section
notation: 20
subclass of: Route Of Delivery
definition: Caesarian Section Medical Procedure. One-third of pregnancies in the US end in C-Sections.
type: QualityValue
subclass of: Pregnancy Characteristic
type: Class

dimethylthiophosphate
notation: DMTP
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite

Metabolite
subclass of: Small Molecule
type: Class
definition: The intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.

Descendant
definition: The child of a human, or any grandchild, great-grandchild, and so on.
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      all values from: Ancestor
      on property: hasRole
    intersection of: SIO_000485
subclass of: Relative
was approved by: PER-Jeanette-Stingone
type: Class

Toluene
type: Class
definition: Toluene is a widely used industrial solvent.
notation: TOL
subclass of: Volatile Organic Compound

Some College
type: Class
notation: 85
definition: Indicates that a person has attended college but that they did not receive any degree.
subclass of: Higher Education
was approved by: PER-Jeanette-Stingone
type: QualityValue

hexadecanoic acid
definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
subclass of: Fatty Acid
type: Class
notation: C160

Preschool Child Behavior Checklist
type: Class
subclass of: Neurocognitive Assessment
definition: Child Behavior Checklist for ages 1 ½ through 5

count unit
type: SIO_000074
notation: count

Cement Floor
type: QualityValue
definition: Cement Floor Type
notation: 10
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Floor Type

Known Food Allergies
type: QualityVariable
subclass of: Medical History
type: Class

Student
type: Class
type: QualityValue
subclass of: Occupation
notation: 66

Education Grade 6
type: Class
notation: 118
type: QualityValue
definition: Finished grade 6
subclass of: Some Middle School

Tooth
definition: Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Tooth_(animal)]
subclass of: Tissue
type: Class

Nickel
type: Class
notation: Ni
definition: NICKEL is a trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
subclass of: Metal

kilogram
notation: kg
type: SIO_000074

Meconium
type: Class
subclass of: Feces
definition: A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth. [database_cross_reference: BTO:0000838]
subclass of: Pregnancy Sample

poise
notation: Poise
type: SIO_000074

Conceiving
subclass of: SIO_000587
comment: to become pregnant with a child.
type: Class

gamma-hexachlorocyclohexane
type: Class
notation: GHCH
subclass of: Organochlorine Compound

2-amnothiazolne-4-carbxylic acid(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCATC

microampere
type: SIO_000074
notation: µA

Retinopathy
notation: 129
definition: Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.
type: Class
subclass of: Phenotype
type: QualityValue

parts per hundred
notation: pph
type: SIO_000074

Annulled
type: Class
notation: 43
type: QualityValue
subclass of: Never Married
definition: A marital status in which a voidable marriage is legally declared null and void, as though it never existed. Specific grounds for annullment vary within the presiding jurisdiction, whether geographic or religious.

Seizures
type: QualityValue
notation: 125
definition: Seizures are an intermittent abnormality of the central nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures.
subclass of: Phenotype
type: Class

Hydrogen–Deuterium Exchange Mass Spectrometer
subclass of: Mass Spectrometer
type: Class
was approved by: PER-Jim-McCusker
definition: Hydrogen–deuterium exchange mass spectrometry can determine the overall deuterium content of molecules which have undergone H/D exchange. Because of the sample preparation required, it is typically considered to provide an accurate measurement of non-exchangeable hydrogen atoms only.

pixels per millimeter
type: SIO_000074
notation: p/mm

newton
notation: Ntn
type: SIO_000074

In Vitro Fertilization
type: Class
subclass of: Assisted Reproductive Therapy
type: QualityValue
notation: 50

Protocatechuic acid ethyl ester
notation: OHEtP
subclass of: Environmental Phenol
type: Class

1-hydroxybenzo[c]-phenanthrene
type: Class
subclass of: PAH
notation: BCP1

Overweight
subclass of: Body Weight Quality
type: Class
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
    on property: hasAttribute
type: QualityValue
notation: 71

Divorced
notation: 40
definition: Indicates a person whose marriage has been legally dissolved and has not remarried.
type: Class
subclass of: Unmarried
type: QualityValue

Fever
definition: Elevated body temperature due to failed thermoregulation.
type: QualityValue
notation: 123
type: Class
subclass of: Phenotype

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2PHEN3

Education Grade 3
subclass of: Some Elementary School
notation: 115
type: Class
type: QualityValue
definition: Finished grade 3

Monocyclohexyl phthalate
type: Class
subclass of: Phthalate
notation: MCHP

Date of Birth
type: QuantityVariable
subclass of: Demographic
type: Class
definition: Date of day on which a person was born.
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000417

Household Income
type: QuantityVariable
definition: A demographic parameter indicating the amount of earnings made by a family.
subclass of: SIO_000052
subclass of: Socioeconomic Status
was approved by: PER-Jeanette-Stingone
type: Class

Trans-Chlordane
subclass of: Organochlorine Compound
type: Class
notation: TCHL

Circumference
subclass of: Anthropometry
type: QuantityVariable
type: Class

active eosinophilic esophagitis
type: Class
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of more than 25 eosinophils per high-power field area, or 0.158 mm^2 (400x).
equivalent class: Restriction
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: hasAttribute
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
  on property: isPhenotypeOf
subclass of: eosinophilic esophagitis

SIO_001068
type: QualityValue
notation: 135

Microwave Oven Count
type: Class
subclass of: Household Appliance Count
editorial note: Putting a note here, but it applies to all of the appliances. These are used to calculate the SES Index that was reported within one of the pilots. So, there needs to be some connection between these terms.
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
definition: Number of machines in the home used to heat up food using microwaves.

Childhood Cohort Study
type: Class
subclass of: CohortStudy

Genotype
subclass of: Medical History
type: Class

2-hydroxychrysene
subclass of: PAH
type: Class
notation: CHRY2

Multiplex real-time PCR
type: Class
subclass of: Polymerase Chain Reaction

Partial match
subclass of: SIO_001167
type: Class

Collection Date of Sample
type: QuantityVariable
definition: Collection Date of Sample
type: Class
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone

kilogram per meter
notation: kg/m
type: SIO_000074

Cobalt
notation: Co
subclass of: Metal
type: Class
definition: COBALT is a trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.

Delivery Characteristics
type: Class
definition: Attributes related to the delivery of a child.
subclass of: StudyIndicator

Mandelic acid
notation: MA
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

Mono-2-(carboxymethyl) hexyl phthalate
subclass of: Phthalate
type: Class
notation: MCMHP

1-hydroxynaphthalene
subclass of: PAH
notation: NAP1
type: Class

Inorganic Mercury (Hg2+)
type: Class
notation: Hg2
subclass of: Mercury Species

Education Grade 1
type: QualityValue
subclass of: Some Elementary School
definition: Finished grade 1
type: Class
notation: 113

Cerebral Malaria
type: QualityValue
subclass of: Malaria
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
notation: 126
type: Class

mono-pentyl phthalate
notation: mPeP
type: Class
subclass of: Phthalate

gamma-linolenic acid
type: Class
definition: A C18, ω-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.
notation: C183N6
subclass of: Fatty Acid

Panel change
subclass of: SIO_001167
type: Class

mono-isobutyl phthalate (DiBP)
type: Class
subclass of: Phthalate
notation: MiBP

Underweight/Normal
notation: 100
subclass of: Restriction
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
  on property: isAttributeOf
subclass of: Body Weight Quality
type: QualityValue
type: Class

Interleukin-21
notation: IL21
subclass of: SIO_010043
type: Class

1-hydroxybenz[a]anthacene
notation: BAA1
type: Class
editorial note: Only found in one journal article, no where else. Maybe mis-spelled?
subclass of: PAH

Hospitalization
definition: Admission to a hospital
type: Class
subclass of: Hospital Utilization
type: QualityValue
subclass of: SIO_001024
notation: 104

Demographic
subclass of: StudyIndicator
editorial note: SDD-2016-1431-P01_SG_Dictionary_SDD_v1.xlsx
was approved by: PER-Jeanette-Stingone
definition: Demographics are quantifiable characteristics of a given population.
type: Class

Light Bulb Count
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000794
type: Class
definition: Total Number of Lightbulbs in the Home
type: QuantityVariable

Interleukin-1 beta
subclass of: SIO_010043
type: Class
subclass of: Biological Response
definition: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
notation: IL1B

Son
type: Class
subclass of: Restriction
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010048
  on property: isRoleOf
subclass of: Child
definition: A son is a male offspring; a boy or man in relation to his parents.

Behavior Rating Inventory of Executive Function – Preschool Version
type: Class
subclass of: Neurocognitive Assessment
definition: Standardized rating scale designed to specifically measure the range of executive function in preschool-aged children

Obvious coarse debris
type: Class
subclass of: SIO_001167

3, 5, 6-trichloro-2-pyridinol
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
notation: TCP
type: Class

Stress Frequency
type: Class
was approved by: PER-Jeanette-Stingone
type: QualityVariable
editorial note: Again, we might want to link this to a specific assessment?
subclass of: Mental Health
definition: How frequently a person gets stressed.
subclass of: SIO_000475

Bisulfite Pyrosequencing
type: Class
subclass of: Nucleic Acid Sequencing

Hydroxycotinine (total)
subclass of: Tobacco Metabolite
label: Hydroxycotinine
notation: HCOTT
notation: HCOT
type: Class

microgram per liter
type: SIO_000074
notation: µg/L

PCB101
notation: PCB101
type: Class
subclass of: Polychlorobiphenyl

pascal
notation: Pa
type: SIO_000074

Ethylbenzene
notation: EB
subclass of: Volatile Organic Compound
type: Class
definition: Ethylbenzene is mainly used in the manufacture of styrene. Acute (short-term) exposure to ethylbenzene in humans results in respiratory effects, such as throat irritation and chest constriction, irritation of the eyes, and neurological effects such as dizziness. Chronic (long-term) exposure to ethylbenzene by inhalation in humans has shown conflicting results regarding its effects on the blood. Animal studies have reported effects on the blood, liver, and kidneys from chronic inhalation exposure to ethylbenzene. Limited information is available on the carcinogenic effects of ethylbenzene in humans. In a study by the National Toxicology Program (NTP), exposure to ethylbenzene by inhalation resulted in an increased incidence of kidney and testicular tumors in rats, and lung and liver tumors in mice. EPA has classified ethylbenzene as a Group D, not classifiable as to human carcinogenicity.

Diet Treatment Medical Therapy
definition: Diet Treatment is a form of Medical Therapy.
subclass of: Medical Therapy Procedure
type: QualityValue
notation: 26
was approved by: PER-Jeanette-Stingone
type: Class

N-Acetyl-S-(2, 4-dimethylphenyl)-L-cysteine + N-Acetyl-S-(2, 5-dimethylphenyl)-L-cysteine + N-Acetyl-S-(3, 4-dimethylphenyl)-L-cysteine
notation: DPMA
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Head Of Household
type: Class
subclass of: SIO_000016
definition: Head of Household is a filing status for individual United States taxpayers. To use the Head of Household filing status, a taxpayer must: (1) Be unmarried or considered unmarried at the end of the year (2) Have paid more than half the cost of keeping up a home for the tax year (either one's own home or the home of a qualifying parent) (3) Usually have a qualifying person who lived with the head in the home for more than half of the tax year unless the qualifying person is a dependent parent.
subclass of: Demographic
definition: The Person is the head of Household
was approved by: PER-Jeanette-Stingone
label: Head of Household
subclass of: Restriction
  all values from: Class
    intersection of: Household
  on property: inRelationTo

katal per liter
notation: kat/l
type: SIO_000074

Interleukin-8
notation: IL8

Color Object Association Test
definition: a reliable and a valid measure of declarative memory for healthy children ages 18-36 months, living in a disadvantaged community
subclass of: Neurocognitive Assessment
type: Class

Phenylglyoxylic acid(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCPHG
subclass of: Volatile Organic Compound
type: Class

RNA
subclass of: Macromolecule
type: Class

Fibrinogen Assay (Clauss method)
subclass of: SIO_001007
type: Class

Some High School
type: QualityValue
definition: Education Level of Some High School
subclass of: High School or Less
notation: 87
was approved by: PER-Jeanette-Stingone
type: Class

Benzophenone-1
notation: BP1
type: Class
subclass of: Benzophenone

Mercapturic acids of acrolein and crotonaldehyde
type: Class
notation: AMA
subclass of: PAH

2-hydroxyfluorene
type: Class
subclass of: PAH
notation: FLUO2

blood lymphocyte count
type: Class
subclass of: SIO_000794

Perfluorononanoic acid
type: Class
notation: PFNA
subclass of: PFC

picomolar
type: SIO_000074
notation: pM

Insulin
subclass of: SIO_010043
type: Class
definition: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes.
subclass of: Biological Response
subclass of: Analyte

microeinstein per square meter per second
type: SIO_000074
notation: µeinstein/sm2

Healthcare Access
type: Class
definition: Healthcare Access
subclass of: StudyIndicator

milligray
notation: mGy
type: SIO_000074

mono(7-carboxyheptyl)phthalate
subclass of: Phthalate
type: Class
notation: mCHpP

Paraben
subclass of: Targeted Analyte
type: Class

Reproductive Health
definition: Reproductive Health Indicator Class
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: StudyIndicator

thawed, hemolyzed (covers all three levels) and exposed to light
type: Class
subclass of: SIO_001167

Unplanned Caesarian Section
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue
definition: Had an unplanned caesarian section.
notation: 23
subclass of: Caesarian Section

Fibrin present
subclass of: SIO_001167
type: Class

Interleukin-17A
notation: IL17A
subclass of: SIO_010043
type: Class

Nicotine-N-oxide
subclass of: Tobacco Metabolite
notation: NICO
type: Class

Nucleic Acid Sequencing
type: Class
subclass of: SIO_001007

Placenta
type: Class
subclass of: Pregnancy Sample
subclass of: Tissue
definition: Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. [database_cross_reference: http://en.wikipedia.org/wiki/Placenta][database_cross_reference: http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm]

kilogram per cubic meter
notation: kg/m3
type: SIO_000074

volt-hour
notation: Vh
type: SIO_000074

Never Married
definition: Indicates a person who has never been married or whose marriages have been annulled.
notation: 38
type: Class
subclass of: Unmarried
type: QualityValue

Value greater than ULOQ
type: Class
subclass of: SIO_001167

2, 3, 4, 5-Tetrachlorophenol
notation: TeCP2345
definition: PHYSICAL DESCRIPTION: Needles (from petroleum ether, ligroin) or beige solid. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

PCB52
notation: PCB52
subclass of: Polychlorobiphenyl
type: Class

Neptunium
subclass of: Metal
definition: Neptunium. A radioactive element of the actinide metals family. NEPTUNIUM has the atomic symbol Np, atomic number 93, and atomic weight 237.
notation: Np
type: Class

Electrospray Ionization Mass Spectrometry
type: Class
definition: Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.
was approved by: PER-Jim-McCusker
subclass of: MassSpectrometry

Common Era
definition: Common era time measurements are referenced against (in relation to) the beginning of the common era, 1 CE (or 1 AD).
equivalent class: Restriction
  has value: First Year of the Common Era
  on property: inRelationTo
subclass of: Relative Time
type: Class

Arsenous ( III) Acid
type: Class
notation: Arsenous (III) Acid
subclass of: Arsenic Species

Separated
notation: 41
subclass of: Married
type: QualityValue
definition: Indicates a person living apart from his/her spouse by legal arrangement.
type: Class

Ethyl paraben
type: Class
subclass of: Paraben
notation: EtPB
definition: Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of ethylparaben is Allergens.

UBERON_0036255
deprecated: true

C-C motif chemokine 20
notation: MIP3A
subclass of: SIO_010043
type: Class

watt
notation: watt
type: SIO_000074

Forceps-Assisted Birth
definition: A vaginal birth with the assistance of forceps to extract the baby.
type: QualityValue
type: Class
subclass of: Vaginal Birth
notation: 25

centimeter
notation: cm
type: SIO_000074

Smoking Status
editorial note: We need to discuss this entire hierarchy.
type: Class
subclass of: Alcohol, Tobacco, and Illicit Drug Use
definition: An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history
type: QualityVariable
subclass of: SIO_001326

parts per quadrillion
type: SIO_000074
notation: ppq

Triclocarban
subclass of: Environmental Phenol
type: Class
notation: TCC
definition: Triclocarban is a triclosan analogue with an antibacterial property. Triclocarban exerts its effect by inhibiting the activity of enoyl-(acyl-carrier protein) (ACP) reductase, widely distributed in bacteria, fungi and plants. ACP reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. As a result, this agent interrupts cell membrane synthesis and leads to bacterial growth inhibition.

Total nicotine
type: Class
subclass of: Tobacco Metabolite
editorial note: Duplicate of NIC?
notation: TNIC

Private Insurance or Self Pay
type: Class
notation: 51
type: QualityValue
subclass of: Insurance

Lymphocyte
subclass of: Leukocyte
definition: A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
type: Class

Anthropometry
was approved by: PER-Jeanette-Stingone
definition: Attributes pertaining to the scientific study of the measurements and proportions of the human body.
type: Class
subclass of: StudyIndicator

Result reported based on fewer replicates than required
subclass of: SIO_001167
type: Class

Domestic Partnership
subclass of: Unmarried
type: QualityValue
notation: 42
definition: Indicates a person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered.
type: Class

Vacuum Cleaner Count
type: Class
type: QuantityVariable
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
definition: Number of appliances in home used for cleaning rugs.

Gold
subclass of: Metal
type: Class
definition: GOLD is a yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
notation: Au

Cyclohexane-1, 2-dicarboxylic acid mono hydroxyisononyl ester (DINCH)
notation: MHNCH

2, 4-Dichlorophenol
subclass of: Environmental Phenol
definition: 2, 4-dichlorophenol is a colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
type: Class
notation: DCP24

PCB153
subclass of: Polychlorobiphenyl
type: Class
notation: PCB153

mass percentage
notation: w/w
type: SIO_000074

Ruthenium
notation: Ru
type: Class
definition: RUTHENIUM is a hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.
subclass of: Metal

kilovolt
type: SIO_000074
notation: kV

Unmarried
type: QualityValue
notation: 46
subclass of: Marital Status
definition: Indicates a person not currently joined in a legally binding matrimonial union.
type: Class

millisecond
notation: ms
type: SIO_000074

2, 2', 3, 4, 4', 5', 6-Heptabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE183
editorial note: To Do: align with CHEBI.
type: Class

SIO_010059
type: QualityValue
notation: 132

Toaster Count
type: QuantityVariable
definition: Number of appliances used to toast bread.
subclass of: Household Appliance Count
type: Class
was approved by: PER-Jeanette-Stingone

2, 2', 4, 4'-Tetrabromodiphenyl ether
notation: BDE47
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Cold Vapor Atomic Fluorescence Spectroscopy Instrument
was approved by: PER-Jim-McCusker
definition: Used in the measurement of trace amounts of volatile heavy metals such as mercury, cold vapour AFS makes use of the unique characteristic of mercury that allows vapour measurement at room temperature.
subclass of: Atomic Fluorescence Spectroscopy Instrument
type: Class

micrograms per deciliter
notation: µg/dl
type: SIO_000074

Nervous System
definition: The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior
subclass of: SIO_010003
type: Class

Pentachlorophenol
subclass of: Environmental Phenol
type: Class
definition: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
notation: PCP

Oxybenzone
type: Class
subclass of: Volatile Organic Compound
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
notation: OXB

From Conception
subclass of: Relative Time
definition: A time in relation to a conception
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving

mono (6-COOH-2-methylheptyl) phthalate
subclass of: Phthalate
type: Class
notation: MCOMHP

femtomolar
notation: fM
type: SIO_000074

Quadrapole Time-of-Flight Liquid Chromotography-Mass Spectrometry
type: Class
subclass of: Liquid Chromotography-Mass Spectrometery

Electron Transfer Dissociation (ETD)
type: Class
subclass of: TandemMassSpectrometry

First Year of the Common Era
type: NamedIndividual

Haptoglobin
type: Class
subclass of: SIO_010043
notation: HAPTOGLOBIN

Parous
notation: 73
subclass of: Parity
type: Class
type: QualityValue

Interleukin-22
subclass of: SIO_010043
type: Class
notation: IL22

PAH
subclass of: Volatile Organic Compound
type: Class

Sibling
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Sibling
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
was approved by: PER-Jeanette-Stingone
subclass of: Relative
type: Class
definition: One of two or more individuals having one or both parents in common. A male sibling is a brother, and a female sibling is a sister. In most societies throughout the world, siblings often grow up together, thereby facilitating the development of strong emotional bonds. The emotional bond between siblings is often complicated and is influenced by factors such as parental treatment, birth order, personality, and personal experiences outside the family. However, there are cases where siblings grow up in separate homes, in different environments.

sievert
type: SIO_000074
notation: Sv

Surface-Induced Dissociation (SID)
type: Class
subclass of: TandemMassSpectrometry

Nornicotine
notation: NORN
subclass of: Tobacco Metabolite
type: Class

Interleukin-10
subclass of: Biological Response
definition: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
type: Class
subclass of: SIO_010043
notation: IL10

Anemia
subclass of: Phenotype
type: QualityValue
notation: 128
definition: A reduction in erythrocytes volume or hemoglobin concentration.
type: Class

Targeted Sequencing
subclass of: Nucleic Acid Sequencing
definition: Nucleic acid sequencing that limits the scope of sequencing by filtering out portions of the nucleic acids that do not meet some criteria.
type: Class

magnetic flux density unit
notation: MFDU
type: SIO_000074

Washing Machine Count
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
definition: Number of machines used for washing clothes in the home.
subclass of: Household Appliance Count
type: Class

Third Trimester
definition: From 29 weeks through 40 weeks.
subclass of: SIO_000417
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
was approved by: PER-Jeanette-Stingone
subclass of: From Conception
type: Class

Body Mass Index
subclass of: Anthropometry
editorial note: Should we note that this is derived from height and weight? JS: I think so
definition: A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length
subclass of: SIO_000052
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Class
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Height
  intersection of: Restriction
    some values from: SIO_000279
    on property: wasDerivedFrom
type: QuantityVariable

Socioeconomic Status
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Socioeconomic Status Indicator Class

disintegrations per second
type: SIO_000074
notation: dps

Liquid Chromatography - Tandem Mass Spectrometer
type: Class
subclass of: Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
subclass of: Liquid Chromatography–Mass Spectrometer
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS is the combination of two mass analyzers in one mass spec instrument.

No FOL result; FOL = 8 ng/mL assumed
subclass of: SIO_001167
type: Class

Heptyl paraben
notation: HePB
subclass of: Paraben
type: Class

parts per billion
type: SIO_000074
notation: ppb

1-hydroxyphenanthrene
subclass of: PAH
type: Class
notation: PHEN1

Metalloproteinase inhibitor 2
notation: TIMP2
subclass of: SIO_010043
type: Class

Fast Food Consumption
type: Class
notation: 16
definition: Whether or not fast food is consumed.
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Fast Food Consumption Frequency

Asian
subclass of: Race
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.
type: Class
notation: 6

parts per million
type: SIO_000074
notation: ppm

Cadmium
notation: Cd
subclass of: Metal
definition: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.
type: Class

4, 4′-(1, 4-Phenylenediisopropylidene)bisphenol
notation: BPP

Nitrogen Oxide
subclass of: Analyte
type: Class

liter per kilogram
notation: l/kg
type: SIO_000074

Severe Malarial Anemia
subclass of: Anemia
type: QualityValue
definition: In holoendemic transmission areas, Severe Malarial Anemia (SMA) is the primary clinical manifestation of severe childhood malaria, with cerebral malaria occurring only in rare cases. Mortality rates from SMA can exceed 30% in pediatric populations residing in holoendemic transmission areas. The pathophysiological processes that contribute to SMA involve direct and indirect destruction of parasitized and non-parasitized red blood cells (RBCs), inefficient and/or suppression of erythropoiesis, and dyserythropoiesis.
type: Class
notation: 127

Teenager
subclass of: Demographic
subclass of: Developmental Quality
notation: 137
was approved by: PER-Jeanette-Stingone
definition: An individual between the ages of 13 and 19.
type: QualityValue
type: Class

1-hydroxychrysene
subclass of: PAH
notation: CHRY1
type: Class

microgram per gram
notation: ug/g
type: SIO_000074

Kaufman ABC Sequence Subscale
definition: Subscale of Kaufman ABC designed to measure the ability to solve problems by remembering and using an ordered series of images or ideas
type: Class
subclass of: Neurocognitive Assessment

microsecond
type: SIO_000074
notation: µs

Bisphenol A
definition: 4, 4'-isopropylidenediphenol is a white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)
type: Class
subclass of: Environmental Phenol
notation: BPA

Perfluorohexanoic acid
type: Class
notation: PFHxA
subclass of: PFC

(15Z)-tetracosenoic acid
notation: C241N9
subclass of: Fatty Acid
type: Class
definition: A tetracosenoic acid having a cis-double bond at position 15.

No Insurance / Self-funded
type: Class
notation: 89
subclass of: Private Insurance or Self Pay
type: QualityValue

Personal Product Use
was approved by: PER-Jeanette-Stingone
type: Class
definition: Personal Product Use Indicator Class
subclass of: StudyIndicator

Electron Capture Dissociation (ECD)
type: Class
subclass of: TandemMassSpectrometry

Blackbody Infrared Radiative Dissociation (BIRD)
type: Class
subclass of: TandemMassSpectrometry

Insurance
type: Class
subclass of: Healthcare Access
type: QualityVariable
subclass of: Socioeconomic Status

Specimen analyzed in singlicate for an assay that requires duplicates
subclass of: SIO_001167
type: Class

dimethylphosphate
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class
editorial note: To Do: align with CHEBI.
notation: DMP

Infinium Methylation EPIC BeadChip Assay
type: Class
subclass of: Methylation Assay
subclass of: Microarray Assay

parasites per microgram
type: SIO_000074
notation: parasites/µL

Father
subclass of: Parent
definition: The male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental legal and social relationship with the child that carries with it certain rights and obligations. An adoptive father is a male who has become the child's parent through the legal process of adoption. A biological father is the male genetic contributor to the creation of the baby, through sexual intercourse or sperm donation. A biological father may have legal obligations to a child not raised by him, such as an obligation of monetary support. A putative father is a man whose biological relationship to a child is alleged but has not been established. A stepfather is a male who is the husband of a child's mother and they may form a family unit, but who generally does not have the legal rights and responsibilities of a parent in relation to the child.
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    some values from: SIO_010048
    on property: hasAttribute

millisievert
notation: mSv
type: SIO_000074

Quality Control
type: Class
subclass of: Analyte
definition: The value contains quality control data

Sleep Characterisitic
subclass of: StudyIndicator
definition: Sleep Characterisitics Indicator Class
type: Class
was approved by: PER-Jeanette-Stingone

mono-(2-ethyl-5-carboxypentyl) phthalate
subclass of: Phthalate
editorial note: Duplicate of MCEPP?
notation: mECPP
type: Class

Mercury Species
subclass of: Targeted Analyte
type: Class

cubic centimeter per mole
type: SIO_000074
notation: cm3/mol

Race
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000475
type: QualityVariable
subclass of: Demographic

Medication
type: QualityVariable
notation: 142
definition: A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product.
subclass of: Prescription Medication and Dietary Supplements
type: Class

Tetrachloroethene
notation: TCE
subclass of: Volatile Organic Compound
definition: TETRACHLOROETHYLENE is a chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
type: Class

Saliva
subclass of: Bodily Fluid
definition: A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. [database_cross_reference: http://en.wikipedia.org/wiki/Saliva][database_cross_reference: GO:0046541]
type: Class

microcurie per milliliter
type: SIO_000074
notation: µcurie/ml

mass density unit
notation: mdu
type: SIO_000074

2, 2', 4'-Tribromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.
notation: BDE17

blood monocyte count
type: Class
subclass of: SIO_000794

Prenatal Smoker
notation: 77
type: Class
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
subclass of: Smoker
type: QualityValue
definition: The quality of having smoked while being pregnant.

Microplate Reader
was approved by: PER-Jim-McCusker
subclass of: PhysicalInstrument
type: Class
definition: Instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 6-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well (8 by 12 matrix) with a typical reaction volume between 100 and 200 µL per well. Higher density microplates (384- or 1536-well microplates) are typically used for screening applications, when throughput (number of samples per day processed) and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 µL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.

N-Acetyl-S-(benzyl)-L-cysteine
notation: BMA
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Did Not Consume Alcohol
type: QualityValue
notation: 53
subclass of: Alcohol Use
type: Class

square meter
notation: m2
type: SIO_000074

Unusually high
type: Class
subclass of: SIO_001167

Landfill Proximity
subclass of: Environmental Exposure
was approved by: PER-Jeanette-Stingone
definition: How close a household is to a landfill.
type: QuantityVariable
subclass of: SIO_000041
type: Class

Roentgen equivalent man
notation: rem
type: SIO_000074

Unknown Education Level
subclass of: Education
notation: 101
type: Class
type: QualityValue
definition: Level of Education is not known
was approved by: PER-Jeanette-Stingone

mono (3-carboxypropyl) phthalate (multiple)
subclass of: Phthalate
type: Class
notation: MCPP

Matrilysin
subclass of: SIO_010043
type: Class
notation: MMP7

Sickle Cell Anemia
definition: A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
subclass of: SIO_010299
type: Class
notation: 122
type: QualityValue
subclass of: Medical History

Benzene
notation: BZ
type: Class
subclass of: Volatile Organic Compound
definition: Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.

docosanoic acid
definition: A straight-chain, C22, long-chain saturated fatty acid.
notation: C220
subclass of: Fatty Acid
type: Class

Hispanic or Latino Ethnicity
subclass of: Ethnicity
notation: 47
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term “Spanish origin” can also be used in addition to “Hispanic or Latino.”
was approved by: PER-Jeanette-Stingone
type: QualityValue
type: Class

pixels per inch
type: SIO_000074
notation: p/in

No Anti Malarial Use
subclass of: Prescription Medication and Dietary Supplements
type: QualityValue
type: Class
notation: 140

Chromium
type: Class
definition: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002, 1985), chromium and some of its compounds have been listed as known carcinogens.
subclass of: Metal
notation: Cr

2, 3, 5, 6-Tetrachlorophenol
subclass of: Environmental Phenol
type: Class
notation: TeCP2356
definition: PHYSICAL DESCRIPTION: Leaflets (from ligroin) or light beige powder. (NTP, 1992)

2-thoxothazlidne-4-carbxylic acid(ng/mL)
type: Class
notation: VOCTTC
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

gram per milliliter
notation: g/ml
type: SIO_000074

electric field strength unit
type: SIO_000074
notation: Efs

mono-2-heptyl phthalate
notation: mHpP
subclass of: Phthalate
type: Class

billion parts per microgram
notation: x109 µL
type: SIO_000074

Education Grade 4
type: Class
subclass of: Elementary School
type: QualityValue
notation: 116
definition: Finished grade 4

Fenton Weighted Z-Score
subclass of: Class
  intersection of: SIO_001245
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: HHEAR_00504
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Fenton Preterm Growth Chart
  intersection of: Restriction
    some values from: Gestational Age at Birth
    on property: wasDerivedFrom
subclass of: SIO_001245
definition: Derived from Birth Weight, Gestational Age, and Child Sex
subclass of: Z-Score
was approved by: PER-Jeanette-Stingone
subclass of: Birth Outcome
type: QuantityVariable
type: Class

Nicotine (total)
subclass of: Tobacco Metabolite
type: Class
notation: NICT
editorial note: To Do: align with CHEBI.

Hexachlorobenzene
notation: HCB
subclass of: Organochlorine Compound
type: Class

4-Hydroxybenzoic acid
subclass of: Environmental Phenol
notation: HB4
type: Class

Weight for Height Z-Score
type: Class
type: QuantityVariable
subclass of: SIO_001245
subclass of: Z-Score
definition: Z-Score of the weight/height ratio at a given age.

3-methipurc acd, 4-methipurc acd(ng/mL)
subclass of: Volatile Organic Compound
type: Class
notation: VOC34M
editorial note: To Do: align with CHEBI.

N-Acetyl-S-(benzyl)-L-cysteine(ng/mL)
notation: VOCBMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Analyzed at a later date than rest of samples on worksheet (not a repeat)
type: Class
subclass of: SIO_001167

Arsenobetaine
subclass of: Arsenic Species
type: Class
notation: Arsenobetaine

Cerebrospinal fluid
definition: A clear, colorless fluid that is found in the brain and spinal cord.
subclass of: SIO_010046
type: Class

Education Grade 2
type: QualityValue
definition: Finished grade 2
notation: 114
subclass of: Some Elementary School
type: Class

curie per liter
type: SIO_000074
notation: curie/l

Child
subclass of: Descendant
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Parent
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
definition: A relationship with a parent (such as sons and daughters of any age).

Biospecimen
type: Class
definition: A biological laboratory specimen held by a biorepository for research. Such a specimen would be taken by sampling so as to be representative of any other specimen taken from the source of the specimen. When biological specimens are stored, ideally they remain equivalent to freshly-collected specimens for the purposes of research.
subclass of: SampleIndicator
subclass of: SIO_010412

Mono-2-ethyl-5-oxohexylterephthalate
notation: MEOHTP

Birth Cohort Study
type: Class
subclass of: CohortStudy

candela per square meter
type: SIO_000074
notation: cd/m2

Initial concentration higher than the highest standard
subclass of: SIO_001167
type: Class

Fatty Acid
definition: Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax.
type: Class
subclass of: Targeted Analyte

Gas Chromatography
subclass of: Chromatography
type: Class

Canned Food Consumption Frequency
type: Class
editorial note: Also want to list this under Environmental Exposures (b/c canned food has chemicals in the lining so sometimes it is used as a proxy)
type: QuantityVariable
definition: Frequency of Canned Food Consumption.
was approved by: PER-Jeanette-Stingone
subclass of: Diet Quantity

Unemployment
definition: The state of not having a job.
notation: 67
type: QualityValue
subclass of: Occupation
type: Class

3-hydroxybenzo[c]-phenanthrene
notation: BCP3
type: Class
subclass of: PAH

Interferon gamma
subclass of: SIO_010043
type: Class
notation: IFNG

Uranium
notation: U
definition: Uranium. A radioactive element of the actinide series of metals. URANIUM has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.
subclass of: Metal
type: Class

linoleic acid
type: Class
notation: C182N6
subclass of: Fatty Acid
definition: An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.

Household
subclass of: Housing Characteristic
definition: A household consists of one or more people who live in the same dwelling and also share meals or living accommodation, and may consist of a single family or some other grouping of people. A single dwelling will be considered to contain multiple households if either meals or living space are not shared. The household is the basic unit of analysis in many social, microeconomic and government models, and is important to the fields of economics and inheritance.
type: Class
subclass of: SIO_001064

3, 4-Dihydroxy benzoic acid
type: Class
subclass of: Environmental Phenol
notation: DHB34

Triclosan
type: Class
definition: Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
notation: TCS
subclass of: Environmental Phenol

Mono-n-octyl phthalate
subclass of: Phthalate
type: Class
notation: MOP

Education Grade 7
notation: 119
subclass of: Some Middle School
type: QualityValue
type: Class
definition: Finished grade 7

thawed and hemolyzed (covers all three levels)
type: Class
subclass of: SIO_001167

Chromatography Instrument
subclass of: PhysicalInstrument
type: Class
was approved by: PER-Jim-McCusker
definition: Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.

2, 2', 4, 4', 5, 5'-Hexabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.
notation: BDE153
type: Class

Electron-Detachment Dissociation (EDD)
type: Class
subclass of: TandemMassSpectrometry

millimeter
notation: mm
type: SIO_000074

DVD Player Count
type: QuantityVariable
definition: Number of devices in the home that play DVDs.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class

Lipemic sample, clarified before running
type: Class
subclass of: SIO_001167

Broken Mitest
type: Class
subclass of: SIO_001167

Selenium
type: Class
notation: Se
definition: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
subclass of: Metal

1-hydroxypyrene
type: Class
notation: PYR1
subclass of: PAH

cubic meter per mole
notation: m3/mol
type: SIO_000074

N-Acetyl-S- (2-carboxyethyl)-L-cysteine
type: Class
notation: CEMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

nanomolal
type: SIO_000074
notation: nmolal

electronvolt
type: SIO_000074
notation: eV

Benzyl paraben
definition: Benzylparaben is a Standardized Chemical Allergen. The physiologic effect of benzylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of benzylparaben is Allergens.
type: Class
notation: BzPB
subclass of: Paraben

Atomic Fluorescence Spectroscopy Instrument
type: Class
definition: a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light.
was approved by: PER-Jim-McCusker
subclass of: PhysicalInstrument

Birth
type: Class
definition: The ending of a pregnancy by one or more babies leaving a woman's uterus by vagina passage or c-section.
subclass of: From Birth
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000417
subclass of: Beginning

Cis-Chlordane
notation: CCHL
type: Class
subclass of: Organochlorine Compound

Granulocyte-macrophage colony-stimulating factor
subclass of: SIO_010043
type: Class
notation: GMCSF

mono benzyl phthalate (BzBP)
notation: MBP
subclass of: Phthalate
type: Class

Reverse-Phase Mass Spectrometry Profiling
type: Class
subclass of: MassSpectrometry

Ancestor
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Relative
definition: An ancestor or forebear is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth). Ancestor is "any person from whom one is descended. In law the person from whom an estate has been inherited."
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Descendant
    intersection of: SIO_000485

2, 2'-dihydroxy-methoxybenzophenone
notation: BP8

Predominantly fibrous material
type: Class
subclass of: SIO_001167

Fresh Vegetable Consumption Frequency
definition: Frequency of Fresh Vegetable Consumption.
subclass of: Diet Quantity
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
type: Class

Bisphenol F
subclass of: Environmental Phenol
type: Class
notation: BPF

Liquid Chromatography Instrument
type: Class
definition: A separation technique in which the mobile phase is a liquid. It can be carried out either in a column or a plane. Present day liquid chromatography that generally utilizes very small packing particles and a relatively high pressure is referred to as high performance liquid chromatography (HPLC).
was approved by: PER-Jim-McCusker
subclass of: Chromatography Instrument

No Hct, Hct=40 assumed
subclass of: SIO_001167
type: Class

High Performance Liquid Chromatography
subclass of: Chromatography
type: Class

N-A-S-(1-HydrxMet)-2-Prpn)-L-Cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCMB1
subclass of: Volatile Organic Compound

Volatile Organic Compound
subclass of: Targeted Analyte
type: Class

Adopted
subclass of: Non-Biological Relative
type: Class
definition: Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents, and, in so doing, permanently transfers all rights and responsibilities, along with filiation, from the biological parent or parents.

ampere
type: SIO_000074
notation: A

Perfluoroheptanoic acid
notation: PFHPA
subclass of: PFC
type: Class

2, 2', 4, 4', 6-Pentabromodiphenyl ether
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
notation: BDE100
type: Class

N-Acetyl-S-(2-cyanoethyl)-L-cysteine
notation: CYMA
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

mole fraction
notation: chi
type: SIO_000074

Phenanthrene tetrol
notation: PHET

Underweight
definition: BMI < 18.5
subclass of: Body Weight Quality
subclass of: Underweight/Normal
notation: 99
type: QualityValue
type: Class
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
    on property: hasAttribute
  on property: isAttributeOf

Monocyte
type: Class
definition: Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.
subclass of: Lymphocyte

minute
type: SIO_000074
notation: min

Coma
subclass of: Phenotype
type: Class
definition: Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli.
type: QualityValue
notation: 124

Polygamous
subclass of: Marital Status
definition: A type of living arrangement or mating system in which at least one member of a relationship has more than one mate.
type: QualityValue
type: Class
notation: 45

millivolt
type: SIO_000074
notation: mV

Solid-Phase Sandwich ELISA
type: Class
subclass of: Sandwich ELISA
was approved by: PER-Jim-McCusker

N-ac-S-(2-carbmo-2-hydxel)-L-cys(ng/mL)
notation: VOCGAM
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Gadolinium
type: Class
definition: Gadolinium. An element of the rare earth family of metals. GADOLINIUM has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
subclass of: Metal
notation: Gd

eosinophilic esophagitis
type: Class
subclass of: esophageal disease

diethylphosphate
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
type: Class
notation: DEP

lux
type: SIO_000074
notation: lx

2, 2', 3, 3', 4, 4', 5, 5', 6, 6'-Decabromodiphenyl ether
notation: BDE209
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether

micromole per liter
type: SIO_000074
notation: µmol/L

Interleukin-4
subclass of: SIO_010043
notation: IL4
type: Class

Run out-of-contol; insufficient sample for repeat analysis
type: Class
subclass of: SIO_001167

octadecanoic acid
subclass of: Fatty Acid
definition: A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
notation: C180
type: Class

area density unit
notation: adu
type: SIO_000074

nanogray
type: SIO_000074
notation: nGy

mono-isononyl phthalate
type: Class
notation: mINP
subclass of: Phthalate

Tobacco Metabolite
type: Class
subclass of: Targeted Analyte

Medical History
definition: Medical History Indicator Class
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator

mono-n-butylphthalate (BzBP, DnBP)
notation: MnBP
type: Class
subclass of: Phthalate

Strontium
notation: Sr
type: Class
subclass of: Metal
definition: STRONTIUM is an element of the alkaline earth family of metals. It has the atomic symbol Sr, atomic number 38, and atomic weight 87.62.

Lipemic and turbid
type: Class
subclass of: SIO_001167

(7Z, 10Z, 13Z, 16Z, 19Z)-docosapentaenoic acid
type: Class
notation: C225N3
definition: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.
subclass of: Fatty Acid

Disease
type: Class
subclass of: Medical History
subclass of: SIO_010299

absorbance unit
notation: AU
type: SIO_000074

Object
type: Class
subclass of: ScienceIndicator

mono ethyl hexyl phthalate
definition: PHYSICAL DESCRIPTION: Clear colorless to cloudy white viscous liquid. (NTP, 1992)
notation: MEHP
type: Class
subclass of: Phthalate

cubic centimeter
type: SIO_000074
notation: cm3

Interlocutory Marital Status
notation: 44
definition: The condition existing when an order or judgement is considered temporary until either a specified period of time has passed or specific information is provided to assist in rendering a permanent decision.
type: Class
subclass of: Marital Status
type: QualityValue

Immunoturbidimetry
was approved by: PER-Jim-McCusker
subclass of: SIO_001007
type: Class
definition: An analytical technique that uses light scattering, a physical phenomenon resulting from the interaction of light with particles in solution, to measure the concentration of particles. The photometric signal is generated by a decrease in light intensity as a direct consequence of increasing turbidity in the reaction well. Immunoturbidimetry uses the classical antigen-antibody reaction. The antigen-antibody complexes are particles which can be optically detected by an photometer.

kilogram meter per second
notation: kg.m/s
type: SIO_000074

count per molar second
type: SIO_000074
notation: 1/Ms

N-Acetyl-S-(1-phenyl-2-hydroxyethyl-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine
notation: PHEMA
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class

High-Performance Liquid Chromatography-Mass Spectrometry
subclass of: Liquid Chromatography–Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
definition: Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. Therefore, LC-MS may be applied in a wide range of sectors including biotechnology, environment monitoring, food processing, and pharmaceutical, agrochemical, and cosmetic industries.
subclass of: High-Performance Liquid Chromatography
was approved by: PER-Jim-McCusker

N-Ace-S-(3-Hydroxypropyl)-L-Cys(ng/mL)
notation: VOCHPM
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

Relative Time
subclass of: SIO_000391
definition: A time in relation to an event
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Process
type: Class

N-Acel-S-(2, 2-Dichlorvinyl)-L-cys(ng/mL)
notation: VOC2DC
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Collision-Induced Dissociation (CID)
type: Class
subclass of: TandemMassSpectrometry

White
notation: 102
type: QualityValue
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
type: Class
subclass of: Race

cubic meter
notation: m3
type: SIO_000074

4, 4'-(hexafluoroisopropylidene)-dephenol
notation: BPAF

Non-smoker
type: Class
subclass of: Smoking Status
type: QualityValue
definition: Doesn't smoker cigarettes.
notation: 59

N-Acetyl-S-(1, 2-dichlorovinyl)-L-cysteine
notation: DCVMA12
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

esophageal disease
type: Class
subclass of: SIO_010299

N-Ethyl Perfluorooctane sulfonamido acetic acid
notation: NETFOSAA

steradian
notation: sr
type: SIO_000074

3-hydroxyfluorene
type: Class
subclass of: PAH
notation: FLUO3

Sample integrity/quality compromised preventing analysis
subclass of: SIO_001167
type: Class

4-nitrophenol
notation: PNP

alpha-hexachlorocyclohexane
subclass of: Organochlorine Compound
notation: AHCH
type: Class

Entity
type: Class
subclass of: ScienceIndicator

Socioeconomic Status Index
editorial note: This is a specific index, derived from other variables. So, it should somehow be connected to this variables. Also, we may want to be more specific about the type of index that it is. Perhaps there should be a general SESIndex and then subclasses of specific measures?
definition: A measure of SES.
type: QuantityVariable
subclass of: Socioeconomic Status
subclass of: SIO_000052
type: Class

tesla
type: SIO_000074
notation: Tesla

Hemolyzed (covers all three levels), lipemic, and icteric
subclass of: SIO_001167
type: Class

Enzyme Immunoassay
type: Class
subclass of: Immunoassay

2, 3, 4, 6-Tetrachlorophenol
subclass of: Environmental Phenol
type: Class
notation: TeCP2346
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)

Household Appliance Count
subclass of: SIO_000794
was approved by: PER-Jeanette-Stingone
subclass of: Housing Characteristic
definition: Total number of appliances that can be found in the home.
type: Class
type: QuantityVariable

Cellular debris present
type: Class
subclass of: SIO_001167

N-methyl Perfluorooctane sulfonamido acetic acid
notation: NMFOSAA
type: Class
subclass of: PFC

2-hydroxyphenanthrene
notation: PHEN2
type: Class
subclass of: PAH

Hemolyzed (covers all three levels) and lipemic
type: Class
subclass of: SIO_001167

degree Fahrenheit
notation: F
type: SIO_000074

Cognitive Task
type: Class
subclass of: Neurocognitive Assessment

Foster
subclass of: Non-Biological Relative
definition: Fosterage, the practice of a family bringing up a child not their own, differs from adoption in that the child's parents, not the foster-parents, remain the acknowledged parents. In many modern western societies foster care can be organized by the state to care for children with troubled family backgrounds, usually on a temporary basis. In many pre-modern societies fosterage was a form of patronage, whereby influential families cemented political relationships by bringing up each other's children, similar to arranged marriages, also based on dynastic or alliance calculations.
type: Class

Unusual color
type: Class
subclass of: SIO_001167

Failed negative control
subclass of: SIO_001167
type: Class

mono (2-ethyl-5-hydroxyhexyl) phthalate
notation: MEHHP
subclass of: Phthalate
type: Class

Neighbor
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000485
subclass of: Demographic
type: Class
definition: A person living near or next door to another person.
subclass of: SIO_000016

m-Xylene*
subclass of: Volatile Organic Compound
type: Class
definition: M-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
notation: MXY

Apgar Score
subclass of: Restriction
  on property: hasValue
  all values from: Datatype
    intersection of: Datatype
      on datatype: integer
      with restrictions:
        min inclusive: 0
    intersection of: Datatype
      on datatype: integer
      with restrictions:
        max inclusive: 10
type: QuantityVariable
type: Class
subclass of: Birth Outcome
was approved by: PER-Jeanette-Stingone
definition: A method to quickly summarize the health of newborn children. The Apgar score was invented by Virginia Apgar in 1952 when Apgar was an anesthesiologist who developed the score in order to ascertain the effects of obstetric anesthesia on babies. The Apgar scale is determined by evaluating the newborn baby on five simple criteria on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10. The five criteria are summarized using words chosen to form a backronym (Appearance, Pulse, Grimace, Activity, Respiration).
subclass of: SIO_001112

Metalloproteinase inhibitor 1
notation: TIMP1
type: Class
subclass of: SIO_010043

Atomic Absorption Spectroscopy
type: Class
subclass of: Atomic Spectroscopy

millimolar
notation: mM
type: SIO_000074

Not Current Student
notation: 141
subclass of: SIO_001326
definition: The state of an individual not currently engaged in educational activity as a pupil.
type: QualityValue
type: Class

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class
notation: AMCC

N-Acetyl-S-(trichlorovinyl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
notation: TCVMA
subclass of: Volatile Organic Compound

Initial concentration higher than the highest standard, insufficient volume for repeat analysis (93, 18)
type: Class
subclass of: SIO_001167

einstein per square meter per second
type: SIO_000074
notation: einstein/sm2

microunits per milliliter
type: SIO_000074
notation: µU/mL

Perfluoro-n-pentanoic acid
type: Class
subclass of: PFC
notation: PFPeA

molar
type: SIO_000074
notation: M

Greater than 99th percentile
subclass of: SIO_001167
type: Class

Private Insurance
type: QualityValue
subclass of: Private Insurance or Self Pay
notation: 103
type: Class

Canned Food Consumption
type: Class
notation: 9
definition: Whether or not canned food is consumed.
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Canned Food Consumption Frequency

cubic decimeter
type: SIO_000074
notation: dm3

cis-vaccenic acid
type: Class
notation: C181N7
subclass of: Fatty Acid
definition: The cis isomer of vaccenic acid.

Leukocyte
type: Class
definition: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
subclass of: Blood Component

Malarial Retinopathy
type: Class
definition: Retinopathy due to malaria.
notation: 130
subclass of: Retinopathy
type: QualityValue

Bedroom Count
type: QuantityVariable
definition: Total Number of Bedrooms in the Home
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Room Count

dimethyldithiophosphate
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
notation: DMDP

Quit Smoking Before Pregnancy
subclass of: Quit Smoking
notation: 81
type: QualityValue
definition: A Previous Smoker who Quit Smoking Before Pregnancy
type: Class
subclass of: Prenatal Nonsmoker
subclass of: Pregnancy Characteristic

Nail
subclass of: Tissue
definition: A nail that is part of a manual digit. [database_cross_reference: OBOL:automatic]
type: Class

Parental Health and Family History
type: Class
definition: Parental Health and Family History Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone

College Graduate
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Higher Education
definition: The quality of having graduated from College
type: QualityValue
notation: 12

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
subclass of: Environmental Phenol
type: Class
notation: PHEN2_PHEN3

picomoles per milliliter
notation: pmol/ml
type: SIO_000074

Plasma
type: Class
subclass of: Blood Component
definition: The liquid component of blood, in which erythrocytes are suspended. [database_cross_reference: http://orcid.org/0000-0002-6601-2165]

Room Count
subclass of: Housing Characteristic
subclass of: SIO_000794
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
definition: Total Number of Rooms in the Home
type: Class

Biological Relative
definition: Being from the same biological kinship as another person. In that aspect, consanguinity is the quality of being descended from the same ancestor as another person.
subclass of: Relative
type: Class

Interfering substances present
type: Class
subclass of: SIO_001167

Concentration
subclass of: Laboratory Result
type: QuantityVariable
type: Class

Alkyl Phosphate Pesticide Metabolite
subclass of: Targeted Analyte
type: Class

Non-Spontaneous Preterm Birth
type: QualityValue
notation: 60
subclass of: Preterm Birth
type: Class

Shotgun Lipidomics
subclass of: Electrospray Ionization Mass Spectrometry
type: Class

milligram per gram
type: SIO_000074
notation: mg/g

African American
type: QualityValue
subclass of: Race
definition: A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American".
was approved by: PER-Jeanette-Stingone
notation: 8
type: Class

milliampere
notation: mA
type: SIO_000074

Aluminum
definition: ALUMINUM is a metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
notation: Al
subclass of: Metal
type: Class

angstrom
notation: Ang
type: SIO_000074

SIO_000980
type: QualityValue
notation: 107

Torn, perforated screen
subclass of: SIO_001167
type: Class

Drinking Water
definition: Drinking Water
definition: Drinking water is water which may be consumed by humans with no adverse effects on their health.
type: Class
subclass of: Environmental Material

compound eye retinal cell
subclass of: Cell
type: Class

volume percentage
notation: %(v/v)
type: SIO_000074

thousand parts per microgram
notation: x103 µL
type: SIO_000074

Stromelysin-2
type: Class
subclass of: SIO_010043
notation: MMP10

Arsenic Species
definition: A molecular entity with arsenic components.
type: Class
subclass of: Targeted Analyte

N-Ace-S-(2-Hydroxyethyl)-L-cys(ng/mL)
notation: VOCHEM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

microcurie
notation: µCi
type: SIO_000074

Monoisopropyl phthalate
notation: MiPP
subclass of: Phthalate
type: Class

Matrix metalloproteinase-9
subclass of: SIO_010043
type: Class
notation: MMP9

No preservative added
type: Class
subclass of: SIO_001167

dehydroepiandrosterone sulfate
subclass of: Analyte
type: Class
definition: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.

2-Methylhippuric acid
subclass of: Volatile Organic Compound
type: Class
notation: MHA2
editorial note: To Do: align with CHEBI.

Marital Status
subclass of: SIO_001326
definition: A person's current conjugal status.
type: QualityVariable
type: Class
subclass of: Demographic
was approved by: PER-Jeanette-Stingone

Red blood cells present
type: Class
subclass of: SIO_001167

turns per second
notation: 1/s
type: SIO_000074

Sputum
subclass of: Bodily Fluid
type: Class
definition: Matter ejected from the lungs, bronchi, and trachea, through the mouth. [database_cross_reference: Dorlands_Medical_Dictionary:MerckSource]

kilovolt-hour
notation: kVh
type: SIO_000074

micromolar
notation: µM
type: SIO_000074

phthalic acid
subclass of: Phthalate
notation: PA
type: Class
definition: PHYSICAL DESCRIPTION: White crystals or fine white powder. (NTP, 1992)

Other Material Finish
type: QualityValue
notation: 70
subclass of: Floor Type
definition: Flooring is made from another unspecified material.
was approved by: PER-Jeanette-Stingone
type: Class

Arsenic (V) Acid
type: Class
notation: Arsenic (V) Acid
subclass of: Arsenic Species

kilobyte
notation: kB
type: SIO_000074

red blood cell count
type: Class
subclass of: SIO_000794

micron pixel
notation: µm pixel
type: SIO_000074

Preterm Birth
subclass of: Birth Outcome
type: Class
was approved by: PER-Jim-McCusker
type: QualityValue
definition: Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.
notation: 88

micrometer
notation: µm
type: SIO_000074

Perfluorooctanesulfonic acid
subclass of: PFC
notation: PFOS
definition: Perfluoroalkyls are stable, synthetic chemicals. Perfluoroalkyls are unique because they repel oil, grease, and water. The two perfluoroalkyls made in the largest amounts in the U. S. areperflurooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Perfluoroalkyls have been used in surface protection products such as carpet and clothing treatments and coating for paper and cardboard packaging. They have also been used in fire-fighting foams.
type: Class

watt per steradian per square meter
notation: W/sr/m2
type: SIO_000074

Interleukin-27 subunit alpha
notation: IL27
subclass of: SIO_010043
type: Class

Dilution required
type: Class
subclass of: SIO_001167

N-Ace-S- (3, 4-Dihidxybutl)-L-Cys(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCDHB
type: Class
editorial note: To Do: align with CHEBI.

alpha-linolenic acid
definition: A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect.
subclass of: Fatty Acid
notation: C183N3
type: Class

million parts per microgram
notation: x106 µL
type: SIO_000074

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCPHE

watt-hour
notation: Wh
type: SIO_000074

N-Acetyl-S-(2-Carbxyethyl)-L-Cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCCEM

megavolt
type: SIO_000074
notation: MV

Interleukin-15
type: Class
notation: IL15
subclass of: SIO_010043

pascal second
notation: Pas
type: SIO_000074

kilogram per liter
type: SIO_000074
notation: kg/L

Technical Post-Middle School
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical Post-Middle School.
notation: 94
type: QualityValue
subclass of: Technical School
type: Class
subclass of: High School or Less

Kaufman ABC
type: Class
subclass of: Neurocognitive Assessment
definition: culturally fair, cognitive ability test for children

Torn bag (Mitest intact, capped)
subclass of: SIO_001167
type: Class

3-Methylhippuric acid + 4-Methylhippuric acid
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: MHA34

No Formal Education
subclass of: Education
notation: 57
type: Class
type: QualityValue
definition: Has not been educated in a formal setting.
was approved by: PER-Jeanette-Stingone

Behavioral Experimental Paradigm Condition
subclass of: Neurocognitive Assessment
type: Class

Study Baseline
definition: Point in study set to initial point.
subclass of: SIO_000417
type: Class

Malaria
subclass of: Medical History
type: Class
notation: 121
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
subclass of: SIO_010299
type: QualityValue

Relative
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Relative
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Demographic
subclass of: SIO_000016
definition: Broadly, kinship patterns may be considered to include people related by both descent – i.e. social relations during development – and by marriage. Human kinship relations through marriage are commonly called "affinity" in contrast to the relationships that arise in one's group of origin, which may be called one's descent group. In some cultures, kinship relationships may be considered to extend out to people an individual has economic or political relationships with, or other forms of social connections. Within a culture, some descent groups may be considered to lead back to gods or animal ancestors (totems). This may be conceived of on a more or less literal basis.

Education Grade
definition: The highest grade of education achieved
type: QualityVariable
was approved by: PER-Jeanette-Stingone
subclass of: Education
type: Class

square millimeter
type: SIO_000074
notation: mm2

2-Aminothiazoline-4-carboxylic acid
notation: ATCA
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

Parity
subclass of: Pregnancy Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: SIO_000794
definition: The number of time that a viviparous organism has given birth
type: QuantityVariable

2, 5-Dichlorophenol
notation: DCP25
definition: PHYSICAL DESCRIPTION: Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 µg/L at 68-72°F; 33 µg/L at 86°F. Taste threshold 0.5 µg/L. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

lumen
type: SIO_000074
notation: lm

Hospital Utilization
definition: Hospital Utilization
subclass of: Healthcare Access
was approved by: PER-Jeanette-Stingone
type: Class

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine
subclass of: Volatile Organic Compound
notation: HEMA2
type: Class

Metal
type: Class
subclass of: Element
definition: For environmental purposes, CHEAR metals are metals and metalliods.

Married
type: QualityValue
notation: 37
type: Class
subclass of: Marital Status
definition: Indicates a person currently joined in a legally binding matrimonial union. Classify common law marriage as married. Includes married couples living together and not living together.

HPLC with Fluorescence Level Detector
definition: HPLC paired with a Fluorescence Level Detector. Fluorescence spectroscopy (also known as fluorometry or spectrofluorometry) is a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light. A complementary technique is absorption spectroscopy. In the special case of single molecule fluorescence spectroscopy, intensity fluctuations from the emitted light are measured from either single fluorophores, or pairs of fluorophores.
subclass of: High-Performance Liquid Chromatography
type: Class

micrograms per meter cubed
type: SIO_000074
notation: µg/m3

Native Hawaiian or Other Pacific Islander
subclass of: Race
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue
definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands.
notation: 55

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
notation: HPMMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

base pair
notation: bp
type: SIO_000074

Mental Health
subclass of: Physical and Mental Assessment
type: Class
was approved by: PER-Jeanette-Stingone
definition: Mental Health Indicator

4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite
type: Class
notation: NNAL

Methyl Paraben
notation: MePB
subclass of: Paraben
definition: Methylparaben is a Standardized Chemical Allergen. The physiologic effect of methylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of methylparaben is Allergens.
type: Class

Subject
was approved by: PER-Jeanette-Stingone
type: Class
definition: A living individual about whom a research investigator (whether a professional or a student) obtains data through 1) intervention or interaction with the individual, or 2) identifiable private information
subclass of: SIO_000016
subclass of: Restriction
  all values from: Class
    intersection of: Study
  on property: inRelationTo

mono-2-ethyl-5- carboxypentyl terephthalate (DEHTP)
notation: MECPTP

Gas Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture (the relative amounts of such components can also be determined). In some situations, GC may help in identifying a compound. In preparative chromatography, GC can be used to prepare pure compounds from a mixture.
subclass of: Chromatography Instrument
type: Class

Previous Smoker
type: QualityValue
notation: 78
type: Class
definition: The quality of having smoked in the past.
subclass of: Smoking Status

Hemoglobin
definition: The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae), as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism.
subclass of: SIO_010043
type: Class
was approved by: PER-Jim-McCusker

3-hydroxyphenanthrene
notation: PHEN3
type: Class
subclass of: PAH

mono-isodecyl phthalate
subclass of: Phthalate
notation: mIDP
type: Class

Polymerase Chain Reaction
type: Class
subclass of: SIO_001007

nanovolt
notation: nV
type: SIO_000074

Pregnancy Characteristic
type: Class
was approved by: PER-Jeanette-Stingone
definition: Pregnancy Characteristic Indicator Class
subclass of: StudyIndicator

Gestational Age
type: QuantityVariable
definition: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization
was approved by: PER-Jeanette-Stingone
subclass of: Age
subclass of: Birth Outcome
type: Class

Phenylglyoxylic acid
notation: PGA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

SIO_010048
notation: 111
type: QualityValue

3-hydroxychrysene
notation: CHRY3
subclass of: PAH
type: Class

terabyte
type: SIO_000074
notation: TB

Visit
type: Class
subclass of: SIO_000417
definition: The time interval of an encounter between a study subject and a study administrator.

Direct Mercury Analyzer
was approved by: PER-Jim-McCusker
definition: Direct mercury analysis incorporates the following sequence: thermal decomposition, catalytic conversion, amalgamation, and atomic absorption spectrophotometry. Controlled heating stages are implemented to first dry and then thermally decompose a sample introduced into a quartz tube. A continuous flow of oxygen carries the decomposition products through a hot catalyst bed where halogens, nitrogen, and sulfur oxides are trapped. All mercury species are reduced to Hg(0) and are then carried along with reaction gases to a gold amalgamator where the mercury is selectively trapped. All nonmercury vapors and decomposition products are flushed from the system by the continuous flow of gas. The amalgamator is subsequently heated and releases all trapped mercury to the single-beam, fixed-wavelength atomic absorption spectrophotometer. Absorbance is measured at 253.7 nm as a function of mercury content
subclass of: PhysicalInstrument
type: Class

Femur
subclass of: SIO_010046
type: Class

milliliter
notation: ml
type: SIO_000074

roentgen
notation: Roentgen
type: SIO_000074

neural cell
type: Class
subclass of: Cell

hematocrit
subclass of: SIO_001018
type: Class

Insurance Type
type: Class
subclass of: Insurance
type: QualityVariable
definition: Insurance Type

Housing Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
definition: Housing Characteristic Indicator Class
subclass of: StudyIndicator

Nicotine
subclass of: Tobacco Metabolite
definition: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
type: Class
notation: NIC

nanogram
type: SIO_000074
notation: ng

decibel
notation: dB
type: SIO_000074

2-Chlorophenol
notation: MCP2
type: Class
subclass of: Environmental Phenol
definition: 2-chlorophenol is a colorless to amber liquid with an unpleasant, penetrating odor. Density 1.265 g / cm3. Sinks in water and slowly dissolves. Freezing point 7°C (46°F). Boiling point 175°C (347°F).

Replicate Number
type: Class
subclass of: SampleIndicator
definition: Replicate Number

Widowed
notation: 39
definition: Indicates a person who is no longer married because of the death of his/her spouse and has not remarried.
type: Class
subclass of: Unmarried
type: QualityValue

Macromolecule
definition: A very large molecule, such as protein, commonly created by polymerization of smaller subunits (monomers). They are typically composed of thousands of atoms or more. The most common macromolecules in biochemistry are biopolymers (nucleic acids, proteins, carbohydrates and polyphenols) and large non-polymeric molecules (such as lipids and macrocycles).
type: Class
subclass of: Biomolecule

Spontaneous Caesarian Section
type: Class
was approved by: PER-Jeanette-Stingone
type: QualityValue
definition: Had a spontaneous caesarian section
notation: 22
subclass of: Caesarian Section

Quantity of sample insufficient for repeat analysis
subclass of: SIO_001167
type: Class

square centimeter
type: SIO_000074
notation: cm2

Adolescent Period
definition: The age span ranging from adolescence to adulthood
subclass of: Restriction
  all values from: Class
    intersection of: SIO_000582
  on property: inRelationTo
type: Class
subclass of: From Birth
subclass of: SIO_000417

glucose
type: Class
subclass of: Analyte
definition: An aldohexose used as a source of energy and metabolic intermediate.

white blood cell count
type: Class
subclass of: SIO_000794

Platelet
subclass of: Blood Component
definition: A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
type: Class

Interleukin-5
type: Class
notation: IL5
subclass of: SIO_010043

Pregnancy Cohort Study
type: Class
subclass of: CohortStudy

arachidonic acid
subclass of: Fatty Acid
type: Class
definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
notation: C204N6

dalton
type: SIO_000074
notation: Da

Hemolyzed (covers all three levels) and contaminated
subclass of: SIO_001167
type: Class

plaque forming unit
notation: pfu
type: SIO_000074

Liquid Chromotography-Multistage Mass Spectrometery
subclass of: MassSpectrometry
type: Class

monoethyl phthalate (DEP)
type: Class
subclass of: Phthalate
notation: MEP

Small clot present
type: Class
subclass of: SIO_001167

mono-isopropyl phthalate
type: Class
notation: mIPrP
subclass of: Phthalate
editorial note: Duplicate of MiPP?

Neurocognitive Assessment
subclass of: Physical and Mental Assessment
type: Class

Tibia
definition: The major preaxial endochondral bone in the posterior zeugopod.
type: Class
subclass of: SIO_010046

Second Trimester
subclass of: SIO_000417
subclass of: From Conception
was approved by: PER-Jeanette-Stingone
definition: From week 13 through 28. Around the middle of the second trimester, movement of the fetus may be felt. At 28 weeks, more than 90% of babies can survive outside of the uterus if provided with high-quality medical care.
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo

Planned Caesarian Section
subclass of: Caesarian Section
notation: 18
type: QualityValue
type: Class
definition: Planned caesarian section.
was approved by: PER-Jeanette-Stingone

Health Maintenance Organization Insurance
type: Class
type: QualityValue
notation: 49
subclass of: Insurance

Diet and Nutrition
definition: Diet and Nutrition Indicator
type: Class
subclass of: StudyIndicator
editorial note: • [WARNING] SDD_00014: The Attributes: [sio:SpecificGravity] are subclasses of neither hasco:StudyIndicator nor hasco:SampleIndicator .
was approved by: PER-Jeanette-Stingone

Technical Post Junior College
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
notation: 93
type: QualityValue
definition: Attended a Technical Post Junior College
subclass of: Technical School

diethylthiophosphate
notation: DETP
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite

Interleukin-17F
subclass of: SIO_010043
type: Class
notation: IL17F

Early Childhood Vigilance Test
subclass of: Neurocognitive Assessment
definition: a computer-based assessment of sustained attention during which the child is required to watch a screen where various animated stimuli disappear and reappear
type: Class

microliter
notation: µl
type: SIO_000074

Platinum
type: Class
notation: Pt
definition: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) PLATINUM is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
subclass of: Metal

eosinophilic esophagitis in remission
type: Class
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of less than 15 eosinophils per high-power field area, or 0.158 mm^2 (400x).
subclass of: eosinophilic esophagitis
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: hasAttribute
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction

microliter per kilogram
type: SIO_000074
notation: µl/kg

counts per minute
type: SIO_000074
notation: cpm

Active Non-Tobacco Smoker
subclass of: Active Smoker
definition: Active Non-Tobacco Smoker
type: QualityValue
type: Class
notation: 1

DNA
type: Class
subclass of: Macromolecule

N-Acetyl-S-(n-propyl)-L-cysteine
notation: BPMA
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

centiRay
notation: cR
type: SIO_000074

megabasepair
notation: Mb
type: SIO_000074

did not precipitate
subclass of: SIO_001167
type: Class

mass-to-charge ratio
notation: Th
type: SIO_000074

valid measurement
subclass of: SIO_001167
type: Class

Mercury
notation: Hg
subclass of: Metal
definition: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
type: Class

Below LOD, results repeated and confirmed (37, 33)
type: Class
subclass of: SIO_001167

Buccal Cell
type: Class
subclass of: Cell
definition: Cells collected from the inner epithelium of the cheek

2, 2'-bis(4-hydroxyphenyl)butane
notation: BPB

Microarray Assay
subclass of: SIO_001007
type: Class
definition: An assay that uses a microarray to perform measurements.

Tellurium
notation: Te
subclass of: Metal
type: Class
definition: Tellurium. An element that is a member of the chalcogen family. TELLURIUM has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.

enzyme unit
type: SIO_000074
notation: enzyme unit

N-acel-S-(1, 2-dichlorovinl)-L-cys(ng/mL)
type: Class
notation: VOC1DC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

normal
type: SIO_000074
notation: Norm

Creatinine
definition: Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
subclass of: Targeted Analyte
notation: CRE
type: Class

enzyme-linked immunosorbent assay (ELISA)
subclass of: Immunoassay
definition: ELISA is an immunoassay that uses antibodies and color change to identify a substance (Wikipedia)
type: Class

Zinc
subclass of: Metal
definition: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
notation: Zn
type: Class

Titanium
type: Class
notation: Ti
definition: TITANIUM is a dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
subclass of: Metal

Patella
subclass of: SIO_010046
definition: The patella, also known as the knee cap or kneepan, is the largest sesamoid bone in the human body. The primary functional role of the patella is knee extension. The patella has convergently evolved in placental mammals and birds; marsupials have only rudimentary, non-ossified patellae. In more primitive tetrapods, including living amphibians and reptiles, the muscle tendons from the upper leg are attached directly to the tibia, and the patella is not present. See also: fabella.
type: Class

count per molar
type: SIO_000074
notation: 1/M

experimentally modified cell in vitro
type: Class
subclass of: Cell

millimole per liter
notation: mmol/L
type: SIO_000074

degree Celsius
notation: C
type: SIO_000074

Abdomen
subclass of: SIO_010046
type: Class

nanosievert
type: SIO_000074
notation: nSv

Biological Sex
subclass of: Demographic
type: QualityVariable
type: Class

N-Ace-S-(2-hydroxypropyl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
type: Class
notation: VOCHP2

mono-carboxy isononyl phthalate
notation: mCINP
type: Class
subclass of: Phthalate

Specimen analyzed with less than usual dilution
subclass of: SIO_001167
type: Class

watt per meter kelvin
type: SIO_000074
notation: W/mK

dots per inch
type: SIO_000074
notation: dpi

Bisphenol S
subclass of: Environmental Phenol
type: Class
notation: BPS

plaque forming unit per milliliter
notation: pfu/ml
type: SIO_000074

mono (2-ethyl-5-oxohexyl) phthalate
subclass of: Phthalate
type: Class
notation: MEOHP

N-Ace-S-(N-methlcarbamoyl)-L-cys(ng/mL)
notation: VOCAMC
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

Polybrominated Diphenyl Ether
type: Class
subclass of: Targeted Analyte

PFC
type: Class
subclass of: Targeted Analyte

Ultra High Performance Liquid Chromatography Instrument
definition: Modern HPLC systems have been improved to work at much higher pressures, and therefore are able to use much smaller particle sizes in the columns (<2 μm). These "Ultra High Performance Liquid Chromatography" systems or UHPLCs can work at up to 120 MPa (17, 405 lbf/in^2), or about 1200 atmospheres.
subclass of: High-Performance Liquid Chromatography
type: Class
was approved by: PER-Jim-McCusker

Histidine-rich protein PFHRP-II
type: Class
subclass of: SIO_010043

Mandelic acid(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCMAD
editorial note: To Do: align with CHEBI.
type: Class

Failed positive control
type: Class
subclass of: SIO_001167

diethyldithiophosphate
notation: DEDP
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.

4-hydroxyphenanthrene
notation: PHEN4
type: Class
subclass of: PAH

meter per second
type: SIO_000074
notation: m/s

millicurie
notation: mCi
type: SIO_000074

TermBirth
type: QualityValue
notation: 97
type: Class
subclass of: Birth Outcome

Sample frozen
subclass of: SIO_001167
type: Class

radian per second per second
type: SIO_000074
notation: alpha

mole
notation: mol
type: SIO_000074

Carbon Tetrachloride
definition: CARBON TETRACHLORIDE is a solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
type: Class
notation: CTET
subclass of: Volatile Organic Compound

N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: AAMA

Tri-Cell DMA-80 Direct Mercury Analyzer
subclass of: Direct Mercury Analyzer
type: Class
definition: The DMA-80 is based on the principles of sample thermal decomposition, mercury amalgamation and atomic absorption detection. The DMA-80 has been used to develop the US EPA method 7473 (Mercury in solids and solutions by thermal decomposition, amalgamation, and atomic absorption spectrophotometry). It is furthermore compliant with ASTM method D-6722-01 (Total mercury in coal and coal combustion residues) and ASTM method D-7623-10 (Total mercury in crude oil).
was approved by: PER-Jim-McCusker

Behavioral Experimental Paradigm
subclass of: Neurocognitive Assessment
type: Class

Interleukin-12 subunit alpha
subclass of: SIO_010043
type: Class
notation: IL12P70

PCB118
subclass of: Polychlorobiphenyl
type: Class
notation: PCB118

Perfluorodecanoic acid
subclass of: PFC
notation: PFDA
type: Class

PCB138
notation: PCB138
type: Class
subclass of: Polychlorobiphenyl

all-cis-icosa-8, 11, 14-trienoic acid
definition: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.
subclass of: Fatty Acid
type: Class
notation: C203N6

mass volume percentage
notation: (w/v)
type: SIO_000074

Post-Pregnancy
was approved by: PER-Jeanette-Stingone
type: Class
definition: The period after birth.
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000582
subclass of: SIO_000417
subclass of: From Birth

nanograms per liter
type: SIO_000074
notation: ng/L

parts per thousand
notation: ppth
type: SIO_000074

disintegrations per minute
notation: dpm
type: SIO_000074

Assisted Reproductive Therapy
type: Class
subclass of: Pregnancy Characteristic
type: QualityValue
notation: 7

Pregnancy Sample
type: Class
subclass of: Biospecimen
definition: A sample that is taken at or near pregnancy or birth.

Childhood Period
definition: The age span ranging from birth to adolescence
subclass of: From Birth
subclass of: Restriction
  all values from: Class
    intersection of: SIO_000582
  on property: inRelationTo
subclass of: SIO_000417
type: Class

Unknown Race
subclass of: Race
type: QualityValue
notation: 48
type: Class
definition: Unknown Race

Conception
subclass of: Beginning
definition: When a sperm fertilizes an egg
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
type: Class
was approved by: PER-Jeanette-Stingone

siemens
type: SIO_000074
notation: 1/AV

Smoker
type: QualityValue
definition: The quality of smoking cigarettes.
subclass of: Smoking Status
notation: 105
type: Class

Perfluorobutanoic acid
type: Class
subclass of: PFC
notation: PFBA

all-cis-5, 8, 11, 14, 17-icosapentaenoic acid
type: Class
notation: C205N3
subclass of: Fatty Acid
definition: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.

byte
type: SIO_000074
notation: Byte

Used Only Anti Malarials or No Medications
notation: 139
type: QualityValue
type: Class
subclass of: Prescription Medication and Dietary Supplements

SIO_000554
notation: 134
type: QualityValue

Preschool Child Behavior Checklist Internalizing Subscale
type: Class
definition: Subscale of preschool CBCL that assesses internalizing behaviors
subclass of: Neurocognitive Assessment

Thallium
subclass of: Metal
definition: THALLIUM is a heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.
type: Class
notation: Tl

Urine grossly hematuric
subclass of: SIO_001167
type: Class

femtoliter
notation: fl
type: SIO_000074

4, 4'-DDT
subclass of: Organochlorine Compound
notation: PPDDT
type: Class

Cousin
definition: A person belonging to the same extended family.
type: Class
subclass of: Relative

Sample older than 2 weeks
subclass of: SIO_001167
type: Class

tetradecanoic acid
definition: A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
notation: C140
subclass of: Fatty Acid
type: Class

gram per liter
type: SIO_000074
notation: g/L

microvolt
notation: µV
type: SIO_000074

Perfluorooctanesulfonamide
subclass of: PFC
type: Class
notation: PFOSA

microgram
notation: µg
type: SIO_000074

Bodily Fluid
subclass of: Biospecimen
definition: Liquids originating from inside the bodies of living people. They include fluids that are excreted or secreted from the body, and body water that normally is not.
type: Class

Body Weight Quality
subclass of: Anthropometry
type: Class
subclass of: SIO_000005
definition: A categorization of body mass relative to the height, as defined using Body Mass Index.

parasite count
subclass of: Concentration
type: Class

kilogram per mole
notation: kg/mol
type: SIO_000074

Value above LOD but below LLOQ
subclass of: SIO_001167
type: Class

monooxoisononyl phthalate (DiNP)
notation: MONP

Barium
notation: Ba
type: Class
definition: BARIUM is an element of the alkaline earth group of metals. It has an atomic symbol Ba, atomic number 56, and atomic weight 138. All of its acid-soluble salts are poisonous.
subclass of: Metal

Fast Food Consumption Frequency
was approved by: PER-Jeanette-Stingone
definition: Frequency of Fast Food Consumption.
type: Class
subclass of: Diet Quantity
type: QuantityVariable

nanomole
type: SIO_000074
notation: nmol

Interleukin-2
notation: IL2
subclass of: SIO_010043
type: Class

Liquid Chromotography-Mass Spectrometery
subclass of: MassSpectrometry
type: Class

Matched Pair of Subjects
definition: A set of 2 subjects which result from a pairing process which assigns subject to a set based on a pairing rule/criteria
type: Class
subclass of: SIO_000616

Valid measurement, results repeated and confirmed (0, 33)
subclass of: SIO_001167
type: Class

8-hydroxy-2'-deoxyguanosine
type: Class
subclass of: Biomolecule
subclass of: Biological Response
definition: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.

mono-carboxy isooctyl phthalate
notation: mCIOP
type: Class
subclass of: Phthalate

N-Ac-S-(2-Hydrxy-3-butnyl)-L-Cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCMB2
subclass of: Volatile Organic Compound

Detectable
type: Class
subclass of: SIO_001167

joule
notation: J
type: SIO_000074

Copper
definition: COPPER is a heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
type: Class
subclass of: Metal
notation: Cu

mebibyte
notation: MiB
type: SIO_000074

picovolt
type: SIO_000074
notation: pV

unit per milliliter
notation: U/ml
type: SIO_000074

becquerel
type: SIO_000074
notation: Bq

2, 4'-DDT
type: Class
notation: OPDDT
subclass of: Organochlorine Compound

Manganese
subclass of: Metal
notation: Mn
definition: MANGANESE is a trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
type: Class

SYNAPT G2-Si Mass Spectrometer
type: Class
was approved by: PER-Jim-McCusker
subclass of: Hydrogen–Deuterium Exchange Mass Spectrometer

Perfume Use
type: QualityValue
subclass of: Personal Product Use
notation: 74
was approved by: PER-Jeanette-Stingone
type: Class

SIO_000751
notation: 133
type: QualityValue

Head
type: Class
subclass of: SIO_010046

Trans-Nonachlor
notation: TNON
type: Class
subclass of: Organochlorine Compound

hertz
type: SIO_000074
notation: Hz

mono-(2-ethylhexyl) terephthalate
notation: MEHTP

native cell
type: Class
subclass of: Cell

mono (5-carboxy-2-ethylpentyl) phthalate (DEHP)
subclass of: Phthalate
notation: MCEPP
type: Class

Agilent 1100 HPLC
subclass of: High-Performance Liquid Chromatography
type: Class
was approved by: PER-Jim-McCusker

2-hydroxynaphthalene
type: Class
subclass of: PAH
notation: NAP2

micromolal
type: SIO_000074
notation: µmol/kg

Cyclomicrons present
type: Class
subclass of: SIO_001167

Polychlorobiphenyl
type: Class
subclass of: Organochlorine Compound

Boiler Count
type: QuantityVariable
definition: A boiler is an object that heats up water. This attribute quantifies the number of boilers in the home.
subclass of: Household Appliance Count
type: Class
was approved by: PER-Jeanette-Stingone

p-Xylene*
subclass of: Volatile Organic Compound
definition: P-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. Freezing point is 56°F. (USCG, 1999)
notation: PXY
type: Class

N-Acetyl-S-(2, 2-dichlorovinyl)-L-cysteine
notation: DCVMA22
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Volatile Organic Compound

Trunk
subclass of: SIO_010046
type: Class
definition: Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present.

Full Time Employment
definition: Employed for a standard number of hours of working time, at least 50% or 20 hours per week.
notation: 64
type: Class
type: QualityValue
subclass of: Occupation

Pathogen Transmission
subclass of: Process

colony forming unit
type: SIO_000074
notation: cfu

Tissue
type: Class
subclass of: Biospecimen

gram per mole
notation: g/mol
type: SIO_000074

Waist
definition: The waist is the part of the abdomen between the rib cage and hips. On people with slim bodies, the waist is the narrowest part of the torso.
subclass of: SIO_010046
type: Class

microgram per milliliter
type: SIO_000074
notation: µg/ml

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: GAMA

cyclic peptide
subclass of: Analyte
type: Class
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).

Interleukin-9
subclass of: SIO_010043
type: Class
notation: IL9

picosecond
notation: ps
type: SIO_000074

femtomole
notation: fmol
type: SIO_000074

N-acetyl-S-(2-cyanoethyl)-L-cyst(ng/mL)
type: Class
notation: VOCCYM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

milliliter per liter
type: SIO_000074
notation: ml/l

Environmental Phenol
subclass of: Targeted Analyte
type: Class

GO_0016265
deprecated: true

foot candle
type: SIO_000074
notation: ft-c

Preschool Child Behavior Checklist Externalizing Subscale
subclass of: Neurocognitive Assessment
definition: Subscale of preschool CBCL that assesses externalizing behaviors
type: Class

Perfluorooctanesulfonate
notation: PFDODA
type: Class
subclass of: PFC

Markedly hemolyzed
type: Class
subclass of: SIO_001167

Retina
type: Class
definition: The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
subclass of: SIO_010003

liter
type: SIO_000074
notation: L

Result repeated and confirmed
subclass of: SIO_001167
type: Class

count per nanomolar
type: SIO_000074
notation: 1/nM

attomole
type: SIO_000074
notation: amol

Interleukin-13
notation: IL13
type: Class
subclass of: SIO_010043

Gray
type: SIO_000074
notation: Gy

Cell
subclass of: Biospecimen
type: Class

Bismuth
notation: Bi
type: Class
subclass of: Metal
definition: BISMUTH is a metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.

gigabyte
type: SIO_000074
notation: GB

millimetres of mercury
notation: mmHg
type: SIO_000074

Pregnancy Complication
notation: 75
type: QualityValue
type: Class
subclass of: Pregnancy Characteristic

Tungsten
definition: Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. TUNGSTEN is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.
subclass of: Metal
type: Class
notation: W

picograms per milliliter
notation: pg/mL
type: SIO_000074

quantity of sample insufficient for analysis
subclass of: SIO_001167
type: Class

Liquid Chromotography -tandem mass spectrometry
subclass of: MassSpectrometry
type: Class

SIO_000784
type: QualityValue
notation: 109

Preschool
notation: 112
type: QualityValue
subclass of: Education Grade
definition: Finished preschool
type: Class

unit per liter
notation: U/l
type: SIO_000074

Cis-Nonachlor
subclass of: Organochlorine Compound
notation: CNON
type: Class

Icteric
type: Class
subclass of: SIO_001167

mono (7-COOH-2-methyloctyl) phthalate
subclass of: Phthalate
type: Class
notation: MCOMOP

6-chloronicotinic acid
notation: CINA6

TNF-alpha
definition: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).
subclass of: SIO_010043
notation: TNFA
subclass of: Biological Response
label: Tumor necrosis factor
type: Class

Biomolecule
definition: A biospecimen that is composed of molecular entities.
type: Class
subclass of: Biospecimen

Cesium
subclass of: Metal
definition: A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.
notation: Cs
type: Class

thawed and clotted
subclass of: SIO_001167
type: Class

picoliter
notation: pl
type: SIO_000074

Non-Biological Relative
type: Class
definition: People that are considered relatives but are not related by blood. This includes relatives by marriage, adoption, or fosterage.
subclass of: Relative

Magnesium
notation: Mg
definition: An element with atomic symbol Mg, atomic number 12, and atomic weight 24.3. Magnesium is an alkaline earth metal and is important to bone structure in human physiology.
subclass of: Metal
type: Class

Hospital Readmissions
subclass of: Hospital Utilization
type: Class
subclass of: SIO_000794
definition: An episode when a patient who had been discharged from a hospital is admitted again within a specified time interval.

curie
type: SIO_000074
notation: Ci

SIO_000981
type: QualityValue
notation: 108

Cognitive Entity
type: Class
subclass of: Neurocognitive Assessment

6-hydroxychrysene
type: Class
subclass of: PAH
notation: CHRY6

From Birth
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: SIO_000582
  on property: inRelationTo
definition: A time in relation to a birth
subclass of: Relative Time

Obese
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
subclass of: Body Weight Quality
notation: 63
type: Class
type: QualityValue

Lab confirmed result
subclass of: SIO_001167
type: Class

Interstitial collagenase
notation: MMP1
type: Class
subclass of: SIO_010043

picomolal
type: SIO_000074
notation: pmolal

SO_0000000
deprecated: true

milligram per deciliter
type: SIO_000074
notation: mg/dl

cells per milliliter
notation: cells per ml
type: SIO_000074

Monomethylarsonic Acid
subclass of: Arsenic Species
notation: Monomethylarsonic Acid
type: Class

mono-methyl phthalate
type: Class
subclass of: Phthalate
notation: mMP

Daughter
subclass of: Child
type: Class
definition: The female offspring in relation to her parents.
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    some values from: SIO_010052
    on property: hasAttribute

meter per second per second
notation: m/s2
type: SIO_000074

gram per cubic centimeter
type: SIO_000074
notation: g/cm3

2-Methylhippuric acid (ng/mL)
notation: VOC2MH
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.

nanomolar
notation: nM
type: SIO_000074

Lymphotoxin-alpha
subclass of: SIO_010043
type: Class
notation: TNFB

picomole
type: SIO_000074
notation: pmol

Very turbid
type: Class
subclass of: SIO_001167

millimole
notation: mmol
type: SIO_000074

RNA Sequencing
subclass of: Nucleic Acid Sequencing
type: Class

Mirex
notation: MIREX
subclass of: Organochlorine Compound
type: Class

4-hydroxybenzophenone
type: Class
subclass of: Benzophenone
notation: OH4BP

dyne per cm
notation: dyn/cm
type: SIO_000074

2-hydroxybenzo[c]-phenanthrene
notation: BCP2
type: Class
subclass of: PAH

2, 2', 4, 4'-tetrahydroxybenzophenone
notation: BP2

centiMorgan
type: SIO_000074
notation: cM

mono-hexyl phthalate
type: Class
subclass of: Phthalate
notation: mHxP

Benzophenone
subclass of: Targeted Analyte
type: Class

candela
notation: cd
type: SIO_000074

Age
subclass of: Demographic
type: QuantityVariable
type: Class

hemoglobin measurement
type: Class
subclass of: Concentration

Hemolyzed (covers all three levels) and debris present
subclass of: SIO_001167
type: Class

abnormal cell
type: Class
subclass of: Cell

Cyclohexane-1, 2-dicarboxylic acid mono carboxyisooctyl ester (DINCH)
notation: MCOCH

Limit of Detection
type: Class
definition: The lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%). The detection limit is estimated from the mean of the blank, the standard deviation of the blank and some confidence factor. Another consideration that affects the detection limit is the accuracy of the model used to predict concentration from the raw analytical signal.
subclass of: Concentration

gram per deciliter
type: SIO_000074
notation: g/dl

Education Grade 5
type: Class
type: QualityValue
subclass of: Some Middle School
definition: Finished grade 5
notation: 117

4-hydroxychrysene
subclass of: PAH
type: Class
notation: CHRY4

volt
type: SIO_000074
notation: Volt

Aligent 8800 Triple Quadrupole ICP-MS
type: Class
subclass of: Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
was approved by: PER-Jim-McCusker

Advanced Graduate Degree
notation: 4
definition: Having earned a pos-baccalaureate degree
type: Class
subclass of: Education
type: QualityValue

gigabasepair
notation: Gb
type: SIO_000074

N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: HPMA2
type: Class

Short sample; sample probe picked up incomplete volume first time
type: Class
subclass of: SIO_001167

picogram
notation: pg
type: SIO_000074

Dimethylarsinic Acid
type: Class
notation: Dimethylarsinic Acid
subclass of: Arsenic Species

deciliter
type: SIO_000074
notation: dl

HOMA-IR
type: SIO_000074
notation: (mg/dL)*(µU/mL)

Infrared Multiphoton Dissociation (IRMPD)
type: Class
subclass of: TandemMassSpectrometry

Interleukin-25
notation: IL17EIL25
type: Class
subclass of: SIO_010043

Organochlorine Compound
type: Class
subclass of: Targeted Analyte

milligram per milliliter
type: SIO_000074
notation: mg/ml

Moderately hemolyzed
type: Class
subclass of: SIO_001167

millimolal
type: SIO_000074
notation: mmol/kg

SIO_010058
notation: 131
type: QualityValue

Difference
type: Class
definition: Variables derived from taking the difference of two other variables. For example, the first difference of a time series {yt} is defined as Dyt = yt - yt-1
subclass of: SIO_000052

Result repeated with diluted sample
subclass of: SIO_001167
type: Class

Propyl paraben
notation: PrPB
type: Class
subclass of: Paraben
definition: Propylparaben is a Standardized Chemical Allergen. The physiologic effect of propylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of propylparaben is Allergens.

Phthalate
type: Class
subclass of: Targeted Analyte

milligram per liter
type: SIO_000074
notation: mg/L

Perfluorobutanesulfonic acid
notation: PFBS
subclass of: PFC
type: Class

Element
subclass of: Targeted Analyte
type: Class

Abnormal hemoglobin variant observed
subclass of: SIO_001167
type: Class

SIO_010052
type: QualityValue
notation: 110

Cell

Datatype
on datatype: float
with restrictions:
  max exclusive: 25.0

rest:
  rest: nil
  first: Datatype
    on datatype: float
    with restrictions:
      max exclusive: 25.0
first: Datatype
  on datatype: float
  with restrictions:
    min exclusive: 18.5

rest:
  first:
    max exclusive: 25
  rest: nil
first:
  min inclusive: 15

max exclusive: 15

Datatype
intersection of: Datatype
  on datatype: float
  with restrictions:
    min exclusive: 25.0
intersection of: Datatype
  on datatype: float
  with restrictions:
    max exclusive: 29.9

max exclusive: 18.5

Datatype
with restrictions:
  min exclusive: 29.9
on datatype: float

Datatype
on datatype: float
with restrictions:
  min exclusive: 25.0

rest: nil
first:
  min exclusive: 25