Post-Pregnancy
subclass of: Restriction
  all values from: Class
    intersection of: birthing
  on property: inRelationTo
was approved by: PER-Jeanette-Stingone
subclass of: From Birth
subclass of: SIO_000417
definition: The period after birth.
type: Class

Light Bulb Count
type: QuantityVariable
definition: Total Number of Lightbulbs in the Home
was approved by: PER-Jeanette-Stingone
subclass of: Housing Characteristic
subclass of: SIO_000794
type: Class

linoleic acid
type: Class
subclass of: Fatty Acid
definition: An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.
notation: C182N6

Native Hawaiian or Other Pacific Islander
type: Class
subclass of: Race
type: QualityValue
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands.
subclass of: Non-White
notation: 55

Quit Smoking Before Pregnancy
type: Class
subclass of: Quit Smoking
subclass of: Prenatal Nonsmoker
notation: 81
subclass of: Pregnancy Characteristic
definition: A Previous Smoker who Quit Smoking Before Pregnancy
type: QualityValue

Retina
type: Class
definition: The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
subclass of: SIO_010003

Underweight/Normal
type: Class
type: QualityValue
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
  on property: isAttributeOf
notation: 100

kilobyte
type: SIO_000074
notation: kB

1, 2-Dichloroethane
type: Class
notation: DE12
definition: Ethylene Dichloride is a clear, colorless, oily, synthetic, flammable liquid chlorinated hydrocarbon with a pleasant chloroform-like smell that emits toxic fumes of hydrochloric acid when heated to decomposition. Ethylene dichloride is primarily used to produce vinyl chloride. Inhalation exposure to this substance induces respiratory distress, nausea and vomiting and affects the central nervous system, liver and kidneys. It is mutagenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05)
subclass of: Volatile Organic Compound

Uranium
definition: Uranium. A radioactive element of the actinide series of metals. URANIUM has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.
type: Class
notation: U
subclass of: Metal

Perfluorooctanesulfonamide
subclass of: PFC
type: Class
notation: PFOSA

SIO_000554
notation: 134
type: QualityValue

lux
type: SIO_000074
notation: lx

Reichert AR200 Handheld Digital Refractometer
type: Class
subclass of: Refractometer
definition: Lightweight digital refractometer designed for the food, beverage, agricultural, industrial-fluid, chemical, petrochemical, pharmaceutical, medical, and plastic industries.
was approved by: PER-Jim-McCusker

Ethnicity
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000475
subclass of: Demographic
type: QualityVariable
type: Class

Nitrogen Oxide
subclass of: Metabolite
type: Class

Slightly hemolyzed
subclass of: SIO_001167
type: Class

ADOS calibrated severity score
type: Class
subclass of: CAO_01168
definition: Calibrated severity score on the Total Standardized Autism Diagnostic Observation Schedule (ADOS).
type: QuantityVariable

Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometer
type: Class
subclass of: Ultra Performance Liquid Chromatography - Mass Spectrometer
was approved by: PER-Jim-McCusker
subclass of: Tandem Mass Spectrometer

Some Postgraduate
definition: Has begun postgraduate (masters, doctorate, etcl) and may or may not have matriculated with a graduate degree.
notation: 187
type: QualityValue
type: Class
subclass of: Restriction
  on property: SIO_000230
  some values from: NCIT C92860
subclass of: Higher Education

1-hydroxybenz[a]anthacene
subclass of: PAH
type: Class
notation: BAA1
editorial note: Only found in one journal article, no where else. Maybe mis-spelled?

Cousin
subclass of: Relative
definition: A person belonging to the same extended family.
type: Class

mono-2-ethyl-5-hydroxyhexyl terephthalate (DEHTP)
notation: MEHHTP

Demographic
definition: Demographics are quantifiable characteristics of a given population.
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
editorial note: SDD-2016-1431-P01_SG_Dictionary_SDD_v1.xlsx

Microarray Assay
definition: An assay that uses a microarray to perform measurements.
type: Class
subclass of: SIO_001007

Pre-Pregnancy
definition: The time before a pregnancy.
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000417
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
type: Class
subclass of: From Conception

Styrene
notation: STY
subclass of: Volatile Organic Compound
type: Class
definition: STYRENE is a colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.

Parity
subclass of: SIO_000794
definition: The number of time that a viviparous organism has given birth
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
subclass of: Pregnancy Characteristic
type: Class

Interleukin-13
subclass of: Protein
type: Class
notation: IL13

Dimethylarsinic Acid
subclass of: Arsenic Species
notation: Dimethylarsinic Acid
type: Class

area density unit
notation: adu
type: SIO_000074

Diet Treatment Medical Therapy
was approved by: PER-Jeanette-Stingone
subclass of: Medical Therapy Procedure
definition: Diet Treatment is a form of Medical Therapy.
type: QualityValue
type: Class
notation: 26

Nicotine
definition: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
notation: NIC
subclass of: Tobacco Metabolite
type: Class

Relative Time
definition: A time in relation to an event
subclass of: SIO_000391
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Process

Perfluoroheptanoic acid
notation: PFHPA
type: Class
subclass of: PFC

pixels per inch
notation: p/in
type: SIO_000074

DVD Player Count
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
type: Class
definition: Number of devices in the home that play DVDs.

Perfluorooctanesulfonate
type: Class
subclass of: PFC
notation: PFDODA

Intelligence Quotient
type: QuantityVariable
definition: A measure of intelligence
was approved by: PER-Jeanette-Stingone
subclass of: Physical and Mental Assessment
type: Class
subclass of: SIO_000052

8-hydroxy-2'-deoxyguanosine
subclass of: Biological Response
type: Class
subclass of: Biomolecule
definition: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.

Drug History
type: QualityVariable
subclass of: Alcohol, Tobacco, and Illicit Drug Use
notation: 14
type: Class

HHEAR
imports: sio.owl
imports: stato.owl
imports: cogat
comment: The Human Health Exposure Analysis Resource (HHEAR) measures exposures that cover the breadth of the “exposome,” which encompasses all environmental exposures including chemical, physical, and biological stressors, as well as lifestyle and social environments, from conception through adulthood. Read more at: https://hhearprogram.org
imports: prov
version IRI: http://purl.org/twc/HHEAR/1.2
imports: cl-basic.owl
imports: uo.owl
imports: cmo.owl
type: Ontology

Preschool
type: QualityValue
subclass of: Education Grade
type: Class
notation: 112
definition: Finished preschool

Limit of Detection
type: Class
definition: The lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%). The detection limit is estimated from the mean of the blank, the standard deviation of the blank and some confidence factor. Another consideration that affects the detection limit is the accuracy of the model used to predict concentration from the raw analytical signal.
subclass of: Concentration

Dead
notation: 173
type: Class
definition: The cessation of life.
subclass of: Destination
type: QualityValue

Malarial Retinopathy
subclass of: Retinopathy
notation: 130
definition: Retinopathy due to malaria.
type: Class
type: QualityValue

Full Time Employment
definition: Employed for a standard number of hours of working time, at least 50% or 20 hours per week.
notation: 64
subclass of: Occupation
type: QualityValue
type: Class

No Sickle Cell Anemia
type: QualityValue
type: Class
subclass of: Health Outcome
notation: 138

Intensive Care Unit
definition: A health care facility unit that provides intensive care to critically ill patients and patients with complex medical problems who require constant monitoring or special therapy.
subclass of: Destination
type: Class
type: QualityValue
notation: 168

High-Performance Liquid Chromatography
was approved by: PER-Jim-McCusker
type: Class
subclass of: Liquid Chromatography Instrument
definition: High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.

Arsenic (V) Acid
notation: Arsenic (V) Acid
subclass of: Arsenic Species
type: Class

Other GI Disease
editorial note: This is a temp concept that needs addressing
subclass of: SIO_010299
type: QualityValue
type: Class
notation: 69
subclass of: Health Outcome

Liquid Chromatography - Tandem Mass Spectrometer
subclass of: Liquid Chromatography–Mass Spectrometer
subclass of: Tandem Mass Spectrometer
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS is the combination of two mass analyzers in one mass spec instrument.
type: Class
was approved by: PER-Jim-McCusker

Annulled
type: Class
definition: A marital status in which a voidable marriage is legally declared null and void, as though it never existed. Specific grounds for annullment vary within the presiding jurisdiction, whether geographic or religious.
type: QualityValue
notation: 43
subclass of: Never Married

White
type: QualityValue
type: Class
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
notation: 102
was approved by: PER-Jeanette-Stingone
subclass of: Race

Visit
subclass of: SIO_000417
definition: The time interval of an encounter between a study subject and a study administrator.
type: Class

gestational diabetes
type: Class
notation: 179
subclass of: DOID 9351
type: QualityValue

Ultra Performance Liquid Chromatography - Mass Spectrometer
subclass of: Ultra High Performance Liquid Chromatography Instrument
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Physical Activity and Fitness
was approved by: PER-Jeanette-Stingone
definition: Physical Activity and Fitness Indicator Class
type: Class
subclass of: StudyIndicator

Private Insurance
type: QualityValue
notation: 103
type: Class
subclass of: Private Insurance or Self Pay

Limit of Quantitation
type: Class
definition: The Limit of Quantitation is the lowest concentration at which the analyte can not only be reliably detected but at which some predefined goals for bias and imprecision are met. The LoQ may be equivalent to the LoD or it could be at a much higher concentration. (Source: Limit of Blank, Limit of Detection and Limit of Quantitation, David A Armbruster and Terry Pry https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556583/)
subclass of: Concentration

Strontium
subclass of: Metal
type: Class
definition: STRONTIUM is an element of the alkaline earth family of metals. It has the atomic symbol Sr, atomic number 38, and atomic weight 87.62.
notation: Sr

African American
subclass of: Race
type: QualityValue
notation: 8
type: Class
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American".
subclass of: Non-White

Education
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Demographic
definition: The act or process of imparting or acquiring knowledge.
type: QualityVariable
subclass of: Socioeconomic Status
subclass of: SIO_000026

Other Material Finish
notation: 70
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Floor Type
definition: Flooring is made from another unspecified material.
type: Class

Computer
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable
definition: A machine used for computation and much more.

Date of Birth
definition: Date of day on which a person was born.
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000417
subclass of: Demographic
type: Class

microvolt
notation: µV
type: SIO_000074

Urine grossly hematuric
subclass of: SIO_001167
type: Class

2-Aminothiazoline-4-carboxylic acid
type: Class
notation: ATCA
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

second
type: SIO_000074
notation: s

Childhood Period
subclass of: From Birth
subclass of: SIO_000417
type: Class
definition: The age span ranging from birth to adolescence
subclass of: Restriction
  all values from: Class
    intersection of: birthing
  on property: inRelationTo

Non-Hispanic Ethnicity
notation: 58
type: QualityValue
subclass of: Ethnicity
type: Class
definition: Non-Hispanic Ethnicity
was approved by: PER-Jeanette-Stingone

Birth
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
definition: The ending of a pregnancy by one or more babies leaving a woman's uterus by vagina passage or c-section.
subclass of: Beginning
subclass of: From Birth
type: Class

Childhood Cohort Study
subclass of: CohortStudy
type: Class

N-Acetyl-S-(n-propyl)-L-cysteine(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCBPM
type: Class

Step
type: Class
definition: A stepfamily is a family where at least one parent has children that are not genetically related to the other spouse or partner. Either one parent may have children from a previous relationship. Children in a stepfamily may live with one biological parent, or they may live with each biological parent for a period of time. In addition, visitation rights mean that children in stepfamilies often have contact with both biological parents, even if they permanently live with only one. A child is referred to as the stepchild, stepdaughter or stepson of their biological parent's new spouse, and that person as the stepparent, stepfather or stepmother of the child. A stepfather is the husband of one's mother, and not one's biological father. A stepmother is the wife of one's father, and not one's biological mother. A step-grandmother is the wife of one's grandfather, and not one's biological grandmother. A step-grandfather is the husband of one's grandmother, and not one's biological grandfather. Similarly, a stepbrother is the son of a stepparent who one is not biologically related to. A stepsister is the daughter of a stepparent to whom one is not biologically related. A step-grandson is the son of a stepson or stepdaughter who one is not biologically related to. A step-granddaughter is the daughter of a stepson or stepdaughter who one is not biologically related. A parent's spouse of the same sex may also count as a stepparent.
subclass of: Non-Biological Relative

nanomolal
type: SIO_000074
notation: nmolal

2, 3', 4, 4'-Tetrabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.
notation: BDE66

Result repeated with diluted sample
subclass of: SIO_001167
type: Class

Hospital Utilization
subclass of: Healthcare Access
type: Class
was approved by: PER-Jeanette-Stingone
definition: Hospital Utilization

Monomethylarsonic Acid
notation: Monomethylarsonic Acid
subclass of: Arsenic Species
type: Class

Mean Concentration
type: Class
subclass of: Concentration
definition: The mean aggregate of multiple concentration measurements of a single substance within a compound substance.
subclass of: SIO_001109
type: QuantityVariable

liter per kilogram
type: SIO_000074
notation: l/kg

2, 2', 3, 4, 4', 5', 6-Heptabromodiphenyl ether
notation: BDE183
subclass of: Polybrominated Diphenyl Ether
editorial note: To Do: align with CHEBI.
type: Class

Proton Pump Inhibitor Treatment
notation: 27
type: QualityValue
editorial note: UPDATE: Yes, add the prescription medication, either as an indicator or as a class under Medical Therapy. Whichever works for the ontology. Why isn't this listed under prescription medication? How do you differentiate between medical therapy and prescription medication?
subclass of: Medical Therapy Procedure
definition: Proton Pump Inhibitor Treatment as a form of medical therapy.
type: Class

gigabasepair
type: SIO_000074
notation: Gb

Lipemic sample, clarified before running
subclass of: SIO_001167
type: Class

Plutonium
type: Class
definition: Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.
notation: Pu
subclass of: Metal

femtogram
type: SIO_000074
notation: fg

2, 3, 4, 6-Tetrachlorophenol
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)
notation: TeCP2346
subclass of: Environmental Phenol
type: Class

formazin nephelometric unit
type: SIO_000074
notation: FNU

Birth Year
definition: The year in which a person was born.
subclass of: SIO_000428
type: Class
notation: 198
type: QualityValue

Mass Spectrometer
type: Class
definition: Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio. In simpler terms, a mass spectrum measures the masses within a sample. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures.
was approved by: PER-Jim-McCusker
subclass of: PhysicalInstrument

joule
notation: J
type: SIO_000074

active eosinophilic esophagitis
equivalent class: Restriction
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
  on property: isPhenotypeOf
subclass of: eosinophilic esophagitis
type: Class
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of more than 25 eosinophils per high-power field area, or 0.158 mm^2 (400x).

4-hydroxyphenanthrene
subclass of: PAH
type: Class
notation: PHEN4

Multi-Family House
type: Class
notation: 176
definition: A residential building designed to hold more than one family.
type: QualityValue
subclass of: Residential Building

8-isoprostane
type: Class
subclass of: Biological Response
subclass of: Biomolecule

Insulin
definition: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes.
subclass of: Protein
subclass of: Metabolite
type: Class

Fibrin present
type: Class
subclass of: SIO_001167

mass-to-charge ratio
notation: Th
type: SIO_000074

Mercapturic acids of acrolein and crotonaldehyde
type: Class
notation: AMA
subclass of: PAH

Daughter
subclass of: Child
type: Class
definition: The female offspring in relation to her parents.
subclass of: Restriction
  all values from: Restriction
    some values from: SIO_010052
    on property: hasAttribute
  on property: isRoleOf

Unknown Education Level
definition: Level of Education is not known
subclass of: Education
notation: 101
type: Class
was approved by: PER-Jeanette-Stingone
type: QualityValue

Used Only Anti Malarials or No Medications
type: Class
type: QualityValue
notation: 139
subclass of: Prescription Medication and Dietary Supplements

asthma
type: Class
notation: 193
type: QualityValue
subclass of: DOID 1176

Fresh Vegetable Consumption Frequency
subclass of: Diet Quantity
type: Class
type: QuantityVariable
definition: Frequency of Fresh Vegetable Consumption.
was approved by: PER-Jeanette-Stingone

kilogram per mole
type: SIO_000074
notation: kg/mol

3-Methylhippuric acid + 4-Methylhippuric acid
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: MHA34

N-Acetyl-S-(2, 4-dimethylphenyl)-L-cysteine + N-Acetyl-S-(2, 5-dimethylphenyl)-L-cysteine + N-Acetyl-S-(3, 4-dimethylphenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: DPMA

Marital Status
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
definition: A person's current conjugal status.
type: QualityVariable
type: Class
subclass of: SIO_001326

Unusual color
type: Class
subclass of: SIO_001167

mono (5-carboxy-2-ethylpentyl) phthalate (DEHP)
subclass of: Phthalate
notation: MCEPP
type: Class

PCB101
type: Class
notation: PCB101
subclass of: Polychlorobiphenyl

Stress
subclass of: Stress Frequency
notation: 92
type: Class
was approved by: PER-Jeanette-Stingone
type: QualityValue
definition: Whether or not a person gets stressed.

N-Acetyl-S-(1-phenyl-2-hydroxyethyl-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine
notation: PHEMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Inductively Coupled Plasma Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: A type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 10^15 (part per quadrillion, ppq) on non-interfered low-background isotopes. This is achieved by ionizing the sample with inductively coupled plasma and then using a mass spectrometer to separate and quantify those ions.

High Performance Liquid Chromatography - Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS (Tandem MS) is the combination of two mass analyzers in one mass spec instrument.
subclass of: High-Performance Liquid Chromatography-Mass Spectrometry
subclass of: Liquid Chromatography - Tandem Mass Spectrometer
type: Class

No Insurance / Self-funded
subclass of: Private Insurance or Self Pay
type: Class
notation: 89
type: QualityValue

N-Ace-S- (3, 4-Dihidxybutl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOCDHB

Cobalt
notation: Co
type: Class
definition: COBALT is a trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
subclass of: Metal

Nornicotine
type: Class
notation: NORN
subclass of: Tobacco Metabolite

Assisted Reproductive Therapy
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue
notation: 7

2, 2', 4, 4'-Tetrabromodiphenyl ether
editorial note: To Do: align with CHEBI.
type: Class
notation: BDE47
subclass of: Polybrominated Diphenyl Ether

nanoliter
notation: nl
type: SIO_000074

Car Count
subclass of: Housing Characteristic
editorial note: Again, this isn't related to physical properties of housing. This is more closely related to Socioeconomic Status. Consider moving it.
type: QuantityVariable
definition: Total Number of Cars in the Home
subclass of: SIO_000794
type: Class

Infinium Methylation EPIC BeadChip Assay
subclass of: Methylation Assay
subclass of: Microarray Assay
type: Class

Owns Home
type: Class
type: QualityValue
notation: 147
definition: This person owns the home they live in.
subclass of: Home Ownership

Ruthenium
notation: Ru
type: Class
subclass of: Metal
definition: RUTHENIUM is a hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.

octadecanoic acid
subclass of: Fatty Acid
definition: A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
type: Class
notation: C180

Ancestor
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Descendant
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
definition: An ancestor or forebear is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth). Ancestor is "any person from whom one is descended. In law the person from whom an estate has been inherited."
type: Class
subclass of: Relative
was approved by: PER-Jeanette-Stingone

nanogram
type: SIO_000074
notation: ng

Education Grade
type: QualityVariable
type: Class
definition: The highest grade of education achieved
subclass of: Education
was approved by: PER-Jeanette-Stingone

3, 4-Dihydroxy benzoic acid
notation: DHB34
subclass of: Environmental Phenol
type: Class

percent
notation: %
type: SIO_000074

micromolar
notation: µM
type: SIO_000074

Nickel
notation: Ni
subclass of: Metal
definition: NICKEL is a trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
type: Class

Income 30001 to 50000
type: QualityValue
subclass of: Household Income
definition: Personal or family annual income bwtween $30,001 and $50,000
notation: 162
type: Class

all-cis-5, 8, 11, 14, 17-icosapentaenoic acid
notation: C205N3
definition: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.
type: Class
subclass of: Fatty Acid

Population Group
subclass of: StudyIndicator
type: QualityVariable
type: Class
definition: A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender)

3-hydroxyphenanthrene
subclass of: PAH
type: Class
notation: PHEN3

Bisphenol F
subclass of: Environmental Phenol
notation: BPF
type: Class

Second Trimester
was approved by: PER-Jeanette-Stingone
definition: From week 13 through 28. Around the middle of the second trimester, movement of the fetus may be felt. At 28 weeks, more than 90% of babies can survive outside of the uterus if provided with high-quality medical care.
subclass of: SIO_000417
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
subclass of: From Conception

Housing Characteristic
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Housing Characteristic Indicator Class
type: Class

nanosecond
notation: ns
type: SIO_000074

Nicotine (total)
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite
type: Class
notation: NICT

Student
type: Class
type: QualityValue
subclass of: Occupation
notation: 66

Mono-2-ethyl-5-oxohexylterephthalate
notation: MEOHTP

College Graduate
type: Class
notation: 12
definition: The quality of having graduated from College
type: QualityValue
was approved by: PER-Jeanette-Stingone
subclass of: Higher Education

Sandwich ELISA
type: Class
subclass of: enzyme-linked immunosorbent assay (ELISA)
definition: Sandwich ELISAs involve attachment of a capture antibody to a solid phase support. Samples containing known or unknown antigen are then added in a matrix or buffer that will minimize attachment to the solid phase. An enzyme-labeled antibody is then added for detection.

Pregnancy
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
subclass of: Pregnancy Characteristic
was approved by: PER-Jeanette-Stingone
definition: The time during which one or more offspring develops inside a woman.
subclass of: From Conception

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2PHEN3

Race
type: Class
type: QualityVariable
subclass of: SIO_000475
subclass of: Demographic
was approved by: PER-Jeanette-Stingone

Height
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Anthropometry
definition: Height
type: QuantityVariable

Weight for Height Z-Score
type: QuantityVariable
subclass of: SIO_001245
subclass of: Z-Score
definition: Z-Score of the weight/height ratio at a given age.
type: Class

2, 2', 4, 4', 5-Pentabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE99
editorial note: To Do: align with CHEBI.
type: Class

Markedly hemolyzed
type: Class
subclass of: SIO_001167

Color Object Association Test
definition: a reliable and a valid measure of declarative memory for healthy children ages 18-36 months, living in a disadvantaged community
type: Class
subclass of: Neurocognitive Assessment

Uncle
notation: 192
subclass of: Relative
definition: The brother of your father or mother or the husband of your aunt.
type: Class
type: QualityValue

Microwave Oven Count
type: Class
editorial note: Putting a note here, but it applies to all of the appliances. These are used to calculate the SES Index that was reported within one of the pilots. So, there needs to be some connection between these terms.
definition: Number of machines in the home used to heat up food using microwaves.
was approved by: PER-Jeanette-Stingone
subclass of: Household Appliance Count
type: QuantityVariable

Nulliparous
subclass of: Parity
type: QualityValue
notation: 62
type: Class

2, 3, 4, 5-Tetrachlorophenol
type: Class
definition: PHYSICAL DESCRIPTION: Needles (from petroleum ether, ligroin) or beige solid. (NTP, 1992)
subclass of: Environmental Phenol
notation: TeCP2345

microgram per liter
type: SIO_000074
notation: µg/L

Apgar Score
subclass of: Restriction
  on property: hasValue
  all values from: Datatype
    intersection of: Datatype
      on datatype: integer
      with restrictions:
        min inclusive: 0
    intersection of: Datatype
      with restrictions:
        max inclusive: 10
      on datatype: integer
definition: A method to quickly summarize the health of newborn children. The Apgar score was invented by Virginia Apgar in 1952 when Apgar was an anesthesiologist who developed the score in order to ascertain the effects of obstetric anesthesia on babies. The Apgar scale is determined by evaluating the newborn baby on five simple criteria on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10. The five criteria are summarized using words chosen to form a backronym (Appearance, Pulse, Grimace, Activity, Respiration).
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable
subclass of: SIO_001112
subclass of: Birth Outcome

Active Non-Tobacco Smoker
definition: Active Non-Tobacco Smoker
notation: 1
subclass of: Active Smoker
type: QualityValue
type: Class

Elementary School
definition: Finished Elementary School
was approved by: PER-Jim-McCusker
type: Class
type: QualityValue
notation: 15
subclass of: Some Elementary School

Increased Body Weight
notation: 72
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
    on property: hasAttribute
type: Class
type: QualityValue
subclass of: Body Weight Quality
definition: BMI > 25

arachidonic acid
definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
notation: C204N6
subclass of: Fatty Acid
type: Class

N-methyl Perfluorooctane sulfonamido acetic acid
notation: NMFOSAA
type: Class
subclass of: PFC

Retinopathy
notation: 129
type: Class
type: QualityValue
definition: Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.
subclass of: Phenotype

Atomic Spectroscopy
type: Class
subclass of: Spectroscopy

Healthcare Access
definition: Healthcare Access
subclass of: StudyIndicator
type: Class

Hair
definition: A filament, mostly protein, that grows from follicles found in the dermis[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Hair]
type: Class
subclass of: Tissue

cell in vitro
type: Class
subclass of: Cell

Education Grade 3
type: QualityValue
type: Class
definition: Finished grade 3
notation: 115
subclass of: Some Elementary School

picogram
type: SIO_000074
notation: pg

picosecond
type: SIO_000074
notation: ps

Nail
type: Class
subclass of: Tissue
definition: A nail that is part of a manual digit. [database_cross_reference: OBOL:automatic]

3-hydroxyfluorene
type: Class
notation: FLUO3
subclass of: PAH

Previous Smoker
definition: The quality of having smoked in the past.
type: QualityValue
notation: 78
subclass of: Smoking Status
type: Class

mono ethyl hexyl phthalate
definition: PHYSICAL DESCRIPTION: Clear colorless to cloudy white viscous liquid. (NTP, 1992)
subclass of: Phthalate
notation: MEHP
type: Class

Pentachlorophenol
notation: PCP
definition: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
subclass of: Environmental Phenol
type: Class

milligram per deciliter
notation: mg/dl
type: SIO_000074

Lipemic and turbid
subclass of: SIO_001167
type: Class

Matrilysin
subclass of: Protein
notation: MMP7
type: Class

Reverse-Phase Mass Spectrometry Profiling
type: Class
subclass of: MassSpectrometry

2, 5-Dichlorophenol
type: Class
definition: PHYSICAL DESCRIPTION: Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 µg/L at 68-72°F; 33 µg/L at 86°F. Taste threshold 0.5 µg/L. (NTP, 1992)
notation: DCP25
subclass of: Environmental Phenol

Adolescent Period
subclass of: Restriction
  all values from: Class
    intersection of: birthing
  on property: inRelationTo
subclass of: From Birth
subclass of: SIO_000417
definition: The age span ranging from adolescence to adulthood
type: Class

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
editorial note: To Do: align with CHEBI.
type: Class
notation: AMCC
subclass of: Volatile Organic Compound

eosinophilic esophagitis
type: Class
subclass of: esophageal disease

mono-n-butylphthalate (BzBP, DnBP)
notation: MnBP
subclass of: Phthalate
type: Class

millimolal
notation: mmol/kg
type: SIO_000074

Tumor necrosis factor
subclass of: Protein
type: Class
label: TNF-alpha
notation: TNFA
definition: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).

Agilent 1100 HPLC
subclass of: High-Performance Liquid Chromatography
type: Class
was approved by: PER-Jim-McCusker

gram per liter
type: SIO_000074
notation: g/L

Control Group
definition: A group used as a standard of comparison in a control experiment.
notation: 200
type: Class
type: QualityValue
subclass of: Population Group

Forceps-Assisted Birth
notation: 25
type: Class
subclass of: Vaginal Birth
definition: A vaginal birth with the assistance of forceps to extract the baby.
type: QualityValue

newton
notation: Ntn
type: SIO_000074

Gas Chromatographer–Mass Spectrometer
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples, including that of material samples obtained from planet Mars during probe missions as early as the 1970s. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification. Like liquid chromatography–mass spectrometry, it allows analysis and detection even of tiny amounts of a substance.
type: Class
subclass of: Gas Chromatography Instrument

Mercury Species
type: Class
subclass of: Targeted Analyte

Tin
definition: TIN is a trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
subclass of: Metal
notation: Sn
type: Class

curie per liter
type: SIO_000074
notation: curie/l

tetradecanoic acid
subclass of: Fatty Acid
type: Class
notation: C140
definition: A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.

Metabolite
definition: The intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
type: Class
subclass of: Small Molecule

Anthropometry
definition: Attributes pertaining to the scientific study of the measurements and proportions of the human body.
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator

2, 4, 5, 6-Tetrachlorophenol
notation: TeCP2456
type: Class
subclass of: Environmental Phenol
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)

Chromatography Instrument
type: Class
definition: Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker

nanomolar
type: SIO_000074
notation: nM

2, 4, 6-Trichlorophenol
subclass of: Environmental Phenol
notation: TCP246
definition: 2 4 6-Trichlorophenol is a synthetic, colorless crystalline solid that is slightly soluble in water and soluble in organic solvents. It has been used primarily in pesticide formulations and as a wood preservative, although most uses have been cancelled in the US. When heated to decomposition, 2, 4, 6-trichlorophenol emits toxic and corrosive fumes of hydrochloric acid and other toxic gases. Exposure of humans to 2, 4, 6-trichrophenol via inhalation has been reported to cause respiratory effects, altered pulmonary function and pulmonary lesions. It is reasonably anticipated to be a human carcinogen. (NCI05)
type: Class

Renter
type: Class
notation: 148
definition: This person rents the home they live in.
type: QualityValue
subclass of: Home Ownership

Inpatient Encounter
definition: A patient encounter where a patient is admitted to a hospital or equivalent facility.
type: QualityValue
subclass of: Destination
type: Class
notation: 169

milligray
type: SIO_000074
notation: mGy

Biomolecule
definition: A biospecimen that is composed of molecular entities.
type: Class
subclass of: Biospecimen

Methylation Assay
definition: An assay that measures the methylation levels of sections of a genome.
type: Class
subclass of: SIO_001007

Unknown Race
notation: 48
definition: Unknown Race
subclass of: Race
type: QualityValue
type: Class

Silver
notation: Ag
subclass of: Metal
definition: Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
type: Class

microgram per milliliter
notation: µg/ml
type: SIO_000074

Occasional Smoker
notation: 158
type: Class
type: QualityValue
subclass of: Smoking Status

nanogray
type: SIO_000074
notation: nGy

2-hydroxyphenanthrene
type: Class
subclass of: PAH
notation: PHEN2

White Hispanic
notation: 145
subclass of: Hispanic or Latino Ethnicity
type: QualityValue
type: Class
definition: White and Hispanic
subclass of: ExO_0000158

Son
type: Class
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010048
definition: A son is a male offspring; a boy or man in relation to his parents.
subclass of: Child

Divorced
subclass of: Unmarried
type: QualityValue
definition: Indicates a person whose marriage has been legally dissolved and has not remarried.
notation: 40
type: Class

N-A-S-(1-HydrxMet)-2-Prpn)-L-Cys(ng/mL)
type: Class
notation: VOCMB1
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Chloroform
subclass of: Volatile Organic Compound
type: Class
notation: CFRM
definition: CHLOROFORM is a commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.

No Hct, Hct=40 assumed
type: Class
subclass of: SIO_001167

candela
notation: cd
type: SIO_000074

Asian
subclass of: Race
subclass of: Non-White
type: Class
notation: 6
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.

Interleukin-12 subunit alpha
subclass of: Protein
type: Class
notation: IL12P70

Monocyte
subclass of: Lymphocyte
definition: Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.
type: Class

Result reported based on fewer replicates than required
subclass of: SIO_001167
type: Class

Environmental Material
type: Class
subclass of: SampleIndicator
subclass of: SIO_010412

Adult
type: QualityValue
type: Class
notation: 3
subclass of: Demographic
definition: Refers to a person above a threshold age.
subclass of: Developmental Quality
was approved by: PER-Jeanette-Stingone

SIO_000981
notation: 108
type: QualityValue

Antimony
subclass of: Metal
type: Class
notation: Sb
definition: ANTIMONY is a metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.

kilodalton
type: SIO_000074
notation: kDa

volt-hour
notation: Vh
type: SIO_000074

Interleukin-17F
type: Class
subclass of: Protein
notation: IL17F

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
type: Class
notation: HPMMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Bodily Fluid
subclass of: Biospecimen
type: Class
definition: Liquids originating from inside the bodies of living people. They include fluids that are excreted or secreted from the body, and body water that normally is not.

Education Grade 1
notation: 113
type: Class
definition: Finished grade 1
type: QualityValue
subclass of: Some Elementary School

2-Chlorophenol
type: Class
notation: MCP2
definition: 2-chlorophenol is a colorless to amber liquid with an unpleasant, penetrating odor. Density 1.265 g / cm3. Sinks in water and slowly dissolves. Freezing point 7°C (46°F). Boiling point 175°C (347°F).
subclass of: Environmental Phenol

unit per liter
notation: U/l
type: SIO_000074

Buccal Cell
definition: Cells collected from the inner epithelium of the cheek
subclass of: Cell
type: Class

VCR Player Count
subclass of: Household Appliance Count
type: Class
definition: Number of devices that play VCRs in the home.
was approved by: PER-Jeanette-Stingone
type: QuantityVariable

Vaginal Birth
subclass of: birthing
type: Class
subclass of: Route Of Delivery
notation: 24
type: QualityValue
subclass of: Pregnancy Characteristic
definition: Had a birthing occur via the vagina.
editorial note: Again, can we add a delivery class

blood lymphocyte count
subclass of: SIO_000794
type: Class

Ethyl paraben
type: Class
subclass of: Paraben
notation: EtPB
definition: Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of ethylparaben is Allergens.

Unplanned Caesarian Section
subclass of: Caesarian Section
type: Class
was approved by: PER-Jeanette-Stingone
definition: Had an unplanned caesarian section.
type: QualityValue
notation: 23

Plasma
subclass of: Blood Component
definition: The liquid component of blood, in which erythrocytes are suspended. [database_cross_reference: http://orcid.org/0000-0002-6601-2165]
type: Class

Quality Control
type: Class
subclass of: Analyte
definition: The value contains quality control data

Child
type: Class
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Parent
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
was approved by: PER-Jeanette-Stingone
subclass of: Descendant
definition: A relationship with a parent (such as sons and daughters of any age).

Cement Floor
definition: Cement Floor Type
type: Class
type: QualityValue
was approved by: PER-Jeanette-Stingone
subclass of: Floor Type
notation: 10

Value less than LOD
subclass of: SIO_001167
type: Class

cells per microliter
notation: cp/µl
type: SIO_000074

Mandelic acid
type: Class
notation: MA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

Higher Education
type: QualityValue
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Education
notation: 31
definition: College or university education beyond the successful completion of high school or grammar school, or the attainment of an approved equivalent

Inductively Coupled Plasma Mass Spectrometry
type: Class
subclass of: MassSpectrometry

parasite count
type: Class
subclass of: Concentration

microsievert
type: SIO_000074
notation: µSv

mass percentage
type: SIO_000074
notation: w/w

No Formal Education
was approved by: PER-Jeanette-Stingone
subclass of: Education
definition: Has not been educated in a formal setting.
type: QualityValue
notation: 57
type: Class

turns per second
notation: 1/s
type: SIO_000074

kilogram meter per second
notation: kg.m/s
type: SIO_000074

bronchiolitis
type: QualityValue
notation: 194
type: Class
subclass of: DOID 850

Lab confirmed result
subclass of: SIO_001167
type: Class

Cord Blood
subclass of: Whole Blood
subclass of: Pregnancy Sample
type: Class
definition: Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Cord_blood]

N-Ace-S-(2-carbamoylethyl)-L-cys(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCAAM

Perfluorohexanoic acid
notation: PFHxA
type: Class
subclass of: PFC

katal
type: SIO_000074
notation: kat

Diet
type: Class
definition: The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.
type: QualityVariable
subclass of: Diet and Nutrition

millivolt
notation: mV
type: SIO_000074

diethylthiophosphate
subclass of: Alkyl Phosphate Pesticide Metabolite
notation: DETP
editorial note: To Do: align with CHEBI.
type: Class

2-hydroxyfluorene
type: Class
subclass of: PAH
notation: FLUO2

candela per square meter
type: SIO_000074
notation: cd/m2

Analyzed at a later date than rest of samples on worksheet (not a repeat)
subclass of: SIO_001167
type: Class

Preschool Child Behavior Checklist Externalizing Subscale
subclass of: Neurocognitive Assessment
definition: Subscale of preschool CBCL that assesses externalizing behaviors
type: Class

Vanadium
notation: V
subclass of: Metal
type: Class
definition: A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.

Autism Spectrum Disorder
type: QualityValue
type: Class
subclass of: Developmental Disorder of Mental Health
notation: 151

Interstitial collagenase
type: Class
subclass of: Protein
notation: MMP1

First Trimester
subclass of: From Conception
type: Class
subclass of: SIO_000417
definition: From pregnancy week 1 through 12 and includes conception. Conception is when the sperm fertilizes the egg. The fertilized egg then travels down the fallopian tube and attaches to the inside of the uterus, where it begins to form the embryo and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus).
was approved by: PER-Jeanette-Stingone
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving

Gas Chromatography
subclass of: Chromatography
type: Class

parts per billion
notation: ppb
type: SIO_000074

N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: MHBMA3

Washing Machine Count
type: QuantityVariable
subclass of: Household Appliance Count
type: Class
was approved by: PER-Jeanette-Stingone
definition: Number of machines used for washing clothes in the home.

Arsenocholine
subclass of: Arsenic Species
notation: Arsenocholine
type: Class

watt per steradian per square meter
type: SIO_000074
notation: W/sr/m2

Non-White
type: Class
subclass of: Race
type: QualityValue
notation: 149
definition: A race other than white.

Mother
definition: A mother is the female parent of a child. Mothers are women who inhabit or perform the role of bearing some relation to their children, who may or may not be their biological offspring. Thus, dependent on the context, women can be considered mothers by virtue of having given birth, by raising their child(ren), supplying their ovum for fertilisation, or some combination thereof. Such conditions provide a way of delineating the concept of motherhood, or the state of being a mother. Women who meet the third and first categories usually fall under the terms 'birth mother' or 'biological mother', regardless of whether the individual in question goes on to parent their child. Accordingly, a woman who meets only the second condition may be considered an adoptive mother, and those who meet only the third a surrogacy mother. The above concepts defining the role of mother are neither exhaustive nor universal, as any definition of 'mother' may differ based on how social, cultural, and religious roles are defined.
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Restriction
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010052
  on property: isRoleOf
subclass of: Parent
type: Class
notation: 189

Specific Gravity
type: Class
editorial note: Why is this here? Maybe it belongs in another list
type: QuantityVariable
subclass of: Targeted Analyte
subclass of: SIO_001018
definition: Specific gravity is the ratio of the density of a substance to the density of a reference substance; equivalently, it is the ratio of the mass of a substance to the mass of a reference substance for the same given volume. Apparent specific gravity is the ratio of the weight of a volume of the substance to the weight of an equal volume of the reference substance. The reference substance is nearly always water at its densest (4°C) for liquids; for gases it is air at room temperature (21°C). Nonetheless, the temperature and pressure must be specified for both the sample and the reference. Pressure is nearly always 1 atm (101.325 kPa). Temperatures for both sample and reference vary from industry to industry.

cigarettes per day
type: Class
type: QualityValue
notation: 152
subclass of: Alcohol, Tobacco, and Illicit Drug Use

Household Income
subclass of: SIO_000052
definition: A demographic parameter indicating the amount of earnings made by a family.
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: Socioeconomic Status
type: QuantityVariable

Preterm Birth
notation: 88
type: QualityValue
definition: Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.
subclass of: Birth Outcome
type: Class
was approved by: PER-Jim-McCusker

High Performance Liquid Chromatography
subclass of: Chromatography
type: Class

micromole
type: SIO_000074
notation: µmol

Income 90001 to 120000
subclass of: Household Income
notation: 165
type: QualityValue
definition: Personal or family annual income bwtween $90,001 and $120,000
type: Class

Sputum
definition: Matter ejected from the lungs, bronchi, and trachea, through the mouth. [database_cross_reference: Dorlands_Medical_Dictionary:MerckSource]
subclass of: Bodily Fluid
type: Class

Tri-Cell DMA-80 Direct Mercury Analyzer
was approved by: PER-Jim-McCusker
subclass of: Direct Mercury Analyzer
definition: The DMA-80 is based on the principles of sample thermal decomposition, mercury amalgamation and atomic absorption detection. The DMA-80 has been used to develop the US EPA method 7473 (Mercury in solids and solutions by thermal decomposition, amalgamation, and atomic absorption spectrophotometry). It is furthermore compliant with ASTM method D-6722-01 (Total mercury in coal and coal combustion residues) and ASTM method D-7623-10 (Total mercury in crude oil).
type: Class

Gel Electrophoresis
definition: Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.
type: Class
subclass of: SIO_001007

2-hydroxychrysene
type: Class
notation: CHRY2
subclass of: PAH

Liquid Chromotography-Mass Spectrometery
type: Class
subclass of: MassSpectrometry

millimetres of mercury
notation: mmHg
type: SIO_000074

1-hydroxynaphthalene
notation: NAP1
type: Class
subclass of: PAH

3,5,6-trichloropyridine-2-one
type: Class
definition: A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.
subclass of: Metabolite

Spontaneous Preterm Birth
subclass of: Preterm Birth
type: QualityValue
type: Class
notation: 91

Sickle Cell Anemia
definition: A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
subclass of: Health Outcome
subclass of: SIO_010299
type: QualityValue
type: Class
notation: 122

Master's Degree
subclass of: Higher Education
subclass of: Some Postgraduate
type: Class
type: QualityValue
notation: 143
definition: The Master's Degree is an award that requires the successful completion of a program of study of at least the full-time equivalent of 1 but not more than two academic years of work beyond the bachelor's degree.

No FOL result; FOL = 8 ng/mL assumed
subclass of: SIO_001167
type: Class

Protocatechuic acid ethyl ester
type: Class
notation: OHEtP
subclass of: Environmental Phenol

Reproductive Health
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class
definition: Reproductive Health Indicator Class

N-Acetyl-S-(phenyl)-L-cysteine(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOCPMA

3-phenoxybenzoic acid
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
type: Class
notation: PBA

Gestational Age
subclass of: Birth Outcome
subclass of: Age
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
definition: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization
type: Class

N-acel-S-(1, 2-dichlorovinl)-L-cys(ng/mL)
notation: VOC1DC
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

abnormal cell
type: Class
subclass of: Cell

liter
notation: L
type: SIO_000074

American Indian Or AlaskanNative
subclass of: Race
notation: 5
type: QualityValue
type: Class
definition: A person having origins in any of the original peoples of North and South America (including Central America) and who maintains tribal affiliation or community attachment.
was approved by: PER-Jeanette-Stingone
subclass of: Non-White

Income 15001 to 30000
type: Class
definition: Personal or family annual income bwtween $15,001 and $30,000
type: QualityValue
notation: 161
subclass of: Household Income

HOMA-IR
notation: (mg/dL)*(µU/mL)
type: SIO_000074

micrometer
notation: µm
type: SIO_000074

international units per litre
type: SIO_000074
notation: IU/L

Tungsten
type: Class
subclass of: Metal
definition: Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. TUNGSTEN is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.
notation: W

Canned Food Consumption Frequency
definition: Frequency of Canned Food Consumption.
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
subclass of: Diet Quantity
editorial note: Also want to list this under Environmental Exposures (b/c canned food has chemicals in the lining so sometimes it is used as a proxy)
type: Class

alpha-linolenic acid
definition: A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect.
notation: C183N3
subclass of: Fatty Acid
type: Class

Childhood
type: QualityValue
definition: A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence.
type: Class
subclass of: Demographic
notation: 11
subclass of: Developmental Quality
was approved by: PER-Jeanette-Stingone

Peripheral Blood Mononuclear Cell
definition: Any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.
type: Class
subclass of: Cell

glucose
subclass of: Biological Response
definition: An aldohexose used as a source of energy and metabolic intermediate.
subclass of: Metabolite
type: Class

Short Stay
type: QualityValue
type: Class
notation: 170
subclass of: Destination
definition: A patient encounter where the patient is admitted to a health care facility for a predetermined length of time, usually less than 24 hours. [def-source:

Smoking Status
notation: 197
editorial note: We need to discuss this entire hierarchy.
subclass of: ExO_0000038
type: QualityValue
type: QualityVariable
definition: An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
subclass of: SIO_001326

Education Grade 6
type: QualityValue
notation: 118
definition: Finished grade 6
type: Class
subclass of: Some Middle School

Perfluorooctanoic acid
notation: PFOA
type: Class
subclass of: PFC

kilogram per square meter
notation: kg/m2
type: SIO_000074

Prescription Medication and Dietary Supplements
subclass of: StudyIndicator
definition: Prescription Medication and Dietary Supplements are forms of medical treatment.
type: Class
was approved by: PER-Jeanette-Stingone

Beryllium
definition: Beryllium. An element with the atomic symbol Be, atomic number 4, and atomic weight 9.01218. Short exposure to this element can lead to a type of poisoning known as BERYLLIOSIS.
subclass of: Metal
notation: Be
type: Class

Long Range Polymerase Chain Reaction
was approved by: PER-Jim-McCusker
type: Class
subclass of: Polymerase Chain Reaction
definition: Amplification of DNA lengths that cannot typically be amplified using routine PCR methods or reagents. For simple DNA templates, polymerases optimized for Long Range PCR can amplify up to 30 kb and beyond. For complex, genomic templates, 20 kb is a typical target.

Income 5000 or Less
subclass of: Household Income
type: QualityValue
definition: Personal or family annual income at or below $5,000
type: Class
notation: 159

Fibrinogen Assay (Clauss method)
type: Class
subclass of: SIO_001007

megavolt
notation: MV
type: SIO_000074

gamma-linolenic acid
definition: A C18, ω-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.
type: Class
notation: C183N6
subclass of: Fatty Acid

watt per steradian
type: SIO_000074
notation: W/sr

microsecond
type: SIO_000074
notation: µs

N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
notation: HPMA2
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

mono-hexyl phthalate
subclass of: Phthalate
type: Class
notation: mHxP

enzyme unit
type: SIO_000074
notation: enzyme unit

colony forming unit per milliliter
notation: cfu/ml
type: SIO_000074

PCB138
type: Class
subclass of: Polychlorobiphenyl
notation: PCB138

phthalic acid
subclass of: Phthalate
type: Class
definition: PHYSICAL DESCRIPTION: White crystals or fine white powder. (NTP, 1992)
notation: PA

Tooth
type: Class
subclass of: Tissue
definition: Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Tooth_(animal)]

cubic meter
notation: m3
type: SIO_000074

Irregular result, no concentration reported
subclass of: SIO_001167
type: Class

PCB180
notation: PCB180
type: Class
subclass of: Polychlorobiphenyl

3-hydroxychrysene
subclass of: PAH
type: Class
notation: CHRY3

High School or Less
type: QualityValue
type: Class
definition: Education Level of High School or Less
subclass of: Education
notation: 33
was approved by: PER-Jeanette-Stingone

Polychlorobiphenyl
type: Class
subclass of: Organochlorine Compound

Interferon lambda-2
subclass of: Protein
type: Class
notation: IL28A

blood monocyte count
subclass of: SIO_000794
type: Class

Mono-n-pentyl phthalate
editorial note: Duplicate of mPeP?
subclass of: Phthalate
type: Class
notation: MPP

Quantity of sample insufficient for repeat analysis
subclass of: SIO_001167
type: Class

experimentally modified cell in vitro
subclass of: Cell
type: Class

4-Chlorophenol
definition: P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible. Used as an intermediate in organic synthesis of dyes and drugs.
type: Class
notation: MCP4
subclass of: Environmental Phenol

Placenta
type: Class
definition: Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. [database_cross_reference: http://en.wikipedia.org/wiki/Placenta][database_cross_reference: http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm]
subclass of: Pregnancy Sample
subclass of: Tissue

Benzo[a]pyrene tetraol
notation: BAPT
type: Class
subclass of: PAH

mono (2-ethyl-5-oxohexyl) phthalate
subclass of: Phthalate
notation: MEOHP
type: Class

Torn bag (Mitest intact, capped)
subclass of: SIO_001167
type: Class

TermBirth
subclass of: Birth Outcome
notation: 97
type: QualityValue
type: Class

Descendant
subclass of: Relative
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      all values from: Ancestor
      on property: hasRole
    intersection of: SIO_000485
type: Class
definition: The child of a human, or any grandchild, great-grandchild, and so on.
was approved by: PER-Jeanette-Stingone

Interferon gamma
subclass of: Protein
notation: IFNG
type: Class

Earth
type: QualityValue
notation: 182

milligram per milliliter
notation: mg/ml
type: SIO_000074

SIO_010052
notation: 110
type: QualityValue

Soil Floor
definition: The flooring is made of soil.
type: Class
was approved by: PER-Jeanette-Stingone
type: QualityValue
notation: 84
subclass of: Floor Type

diethyldithiophosphate
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
notation: DEDP

Benzene
type: Class
subclass of: Volatile Organic Compound
notation: BZ
definition: Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.

Toaster Count
was approved by: PER-Jeanette-Stingone
definition: Number of appliances used to toast bread.
type: Class
subclass of: Household Appliance Count
type: QuantityVariable

Transfer
type: QualityValue
type: Class
notation: 172
subclass of: Destination
definition: The act of conveying or transporting from one place to another.

billion parts per microgram
type: SIO_000074
notation: x109 µL

Public Insurance
notation: 79
type: Class
type: QualityValue
subclass of: Insurance

plaque forming unit
notation: pfu
type: SIO_000074

Ethyl mercury (C2H5Hg+)
type: Class
subclass of: Mercury Species
notation: C2H5Hg

Repeat Caesarian Section
subclass of: Caesarian Section
type: Class
type: QualityValue
definition: Had Repeat Caesarian Section
notation: 21

Interleukin-17A
type: Class
subclass of: Protein
notation: IL17A

Detectable
subclass of: SIO_001167
type: Class

Medical Therapy Procedure
was approved by: PER-Jeanette-Stingone
subclass of: SIO_001024
definition: Medical Therapy Procedure to aide in treatment.
type: QualityVariable
subclass of: Medical History
type: Class

cubic centimeter per mole
notation: cm3/mol
type: SIO_000074

Gravida
type: QuantityVariable
definition: Pregnancy Count, regardless of whether pregnancy was carried to Term.
subclass of: SIO_000794
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Pregnancy Characteristic

Volatile Organic Compound
type: Class
subclass of: Targeted Analyte

Serum
subclass of: Blood Component
definition: Liquid derived from blood plasma that has clotting factors removed. [database_cross_reference: http://en.wikipedia.org/wiki/Serum_(blood)][database_cross_reference: http://orcid.org/0000-0002-6601-2165]
type: Class

count per nanomolar
type: SIO_000074
notation: 1/nM

3, 5, 6-trichloro-2-pyridinol
type: Class
notation: TCP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite

Small Molecule
type: Class
definition: A small molecule is a low molecular weight (< 900 daltons) organic compound that may help regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
subclass of: Biomolecule

Neptunium
definition: Neptunium. A radioactive element of the actinide metals family. NEPTUNIUM has the atomic symbol Np, atomic number 93, and atomic weight 237.
type: Class
subclass of: Metal
notation: Np

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOCMB3

Blood Component
subclass of: Bodily Fluid
type: Class
definition: A derivable component of whole blood.

Technical Post Primary School
subclass of: High School or Less
subclass of: Technical School
notation: 95
definition: Attended a Technical Post Primary School
type: Class
type: QualityValue
was approved by: PER-Jeanette-Stingone

A Sample has a Pairing
subclass of: SIO_001049
editorial note: This actually should be a process. What should we do?
type: Class
definition: Refers to having paired samples.
was approved by: PER-Jeanette-Stingone

N-Ace-S-(3-Hydroxypropyl)-L-Cys(ng/mL)
notation: VOCHPM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Vacuum Cleaner Count
type: Class
subclass of: Household Appliance Count
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
definition: Number of appliances in home used for cleaning rugs.

N-Acetyl-S-(trichlorovinyl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
type: Class
notation: VOCTCV
editorial note: To Do: align with CHEBI.

Haircare Product Use
type: Class
notation: 30
type: QualityValue
was approved by: PER-Jeanette-Stingone
subclass of: Personal Product Use

Interleukin-22
subclass of: Protein
notation: IL22
type: Class

Tandem Mass Spectrometer
definition: Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages. In a tandem mass spectrometer, ions are formed in the ion source and separated by mass-to-charge ratio in the first stage of mass spectrometry (MS1). Ions of a particular mass-to-charge ratio (precursor ions) are selected and fragment ions (product ions) are created by collision-induced dissociation, ion-molecule reaction, photodissociation, or other process. The resulting ions are then separated and detected in a second stage of mass spectrometry (MS2).
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker

Shotgun Lipidomics
subclass of: Electrospray Ionization Mass Spectrometry
type: Class

Neighbor
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000485
type: Class
subclass of: SIO_000016
subclass of: Demographic
definition: A person living near or next door to another person.

Toluene
subclass of: Volatile Organic Compound
type: Class
notation: TOL
definition: Toluene is a widely used industrial solvent.

Reactive Airway Disease
subclass of: NCIT C27557
notation: 186
type: Class
type: QualityValue
definition: Coughing, wheezing, or shortness of breath that is triggered by allergens, infection, or other irritants. [def-source: NCI]

Fenton Weighted Z-Score
subclass of: Class
  intersection of: SIO_001245
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: HHEAR_00504
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Fenton Preterm Growth Chart
  intersection of: Restriction
    some values from: Gestational Age at Birth
    on property: wasDerivedFrom
definition: Derived from Birth Weight, Gestational Age, and Child Sex
subclass of: SIO_001245
type: Class
subclass of: Z-Score
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
subclass of: Birth Outcome

Methyl Paraben
notation: MePB
subclass of: Paraben
definition: Methylparaben is a Standardized Chemical Allergen. The physiologic effect of methylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of methylparaben is Allergens.
type: Class

Leukocyte
type: Class
definition: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
subclass of: Blood Component

Waist
definition: The waist is the part of the abdomen between the rib cage and hips. On people with slim bodies, the waist is the narrowest part of the torso.
subclass of: SIO_010046
type: Class

t, t-Muconic acid(ng/mL)
notation: VOCMUC
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

Some High School
notation: 87
subclass of: High School or Less
definition: Education Level of Some High School
type: Class
type: QualityValue
was approved by: PER-Jeanette-Stingone

Home
subclass of: Destination
type: QualityValue
notation: 167
type: Class
definition: A person's place of residence.

Insurance Type
type: Class
type: QualityVariable
definition: Insurance Type
subclass of: Insurance

Pathogen Transmission
subclass of: Process

Small clot present
subclass of: SIO_001167
type: Class

lumen
type: SIO_000074
notation: lm

Childhood Baseline
subclass of: SIO_000417
subclass of: Restriction
  all values from: Class
    intersection of: Childhood Period
  on property: inRelationTo
subclass of: Study Baseline
definition: A point in a study set to the initial point which occurs during the study subject's childhood period.
type: Class

Father
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    on property: hasAttribute
    some values from: SIO_010048
definition: The male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental legal and social relationship with the child that carries with it certain rights and obligations. An adoptive father is a male who has become the child's parent through the legal process of adoption. A biological father is the male genetic contributor to the creation of the baby, through sexual intercourse or sperm donation. A biological father may have legal obligations to a child not raised by him, such as an obligation of monetary support. A putative father is a man whose biological relationship to a child is alleged but has not been established. A stepfather is a male who is the husband of a child's mother and they may form a family unit, but who generally does not have the legal rights and responsibilities of a parent in relation to the child.
notation: 188
was approved by: PER-Jeanette-Stingone
type: QualityValue
subclass of: Parent
type: Class

radian per second
notation: rad/s
type: SIO_000074

Cyclomicrons present
subclass of: SIO_001167
type: Class

Competitive-inhibition enzyme-linked immunosorbent assay
subclass of: enzyme-linked immunosorbent assay (ELISA)
type: Class

Subject
definition: A living individual about whom a research investigator (whether a professional or a student) obtains data through 1) intervention or interaction with the individual, or 2) identifiable private information
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Study
subclass of: SIO_000016

Preschool Child Behavior Checklist
type: Class
subclass of: Neurocognitive Assessment
definition: Child Behavior Checklist for ages 1 ½ through 5

meter per second per second
notation: m/s2
type: SIO_000074

Blackbody Infrared Radiative Dissociation (BIRD)
type: Class
subclass of: TandemMassSpectrometry

Mirex
notation: MIREX
type: Class
subclass of: Organochlorine Compound

Targeted Analyte
subclass of: Analyte
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: StudyIndicator
definition: A targeted analyte is one that has been selected by the CHEAR program as a prioritized analyte for CHEAR lab hubs to measure and has been carried over to HHEAR.

Widowed
type: QualityValue
definition: Indicates a person who is no longer married because of the death of his/her spouse and has not remarried.
notation: 39
subclass of: Unmarried
type: Class

hematocrit
subclass of: SIO_001018
type: Class

Hydrogen–Deuterium Exchange Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Hydrogen–deuterium exchange mass spectrometry can determine the overall deuterium content of molecules which have undergone H/D exchange. Because of the sample preparation required, it is typically considered to provide an accurate measurement of non-exchangeable hydrogen atoms only.

micromolal
notation: µmol/kg
type: SIO_000074

Prenatal Smoker
type: Class
subclass of: Smoker
type: QualityValue
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
notation: 77
definition: The quality of having smoked while being pregnant.

Technical Post-Middle School
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical Post-Middle School.
subclass of: Technical School
subclass of: High School or Less
type: Class
type: QualityValue
notation: 94

Mexico
type: QualityValue
notation: 183

gigabyte
notation: GB
type: SIO_000074

4, 4'-cyclo-hexylidenebisphenol
notation: BPZ

thawed and clotted
type: Class
subclass of: SIO_001167

Atomic Emission Spectroscopy
type: Class
subclass of: Atomic Spectroscopy

Competitive Immunoassay
subclass of: Immunoassay
type: Class

Perfluorononanoic acid
subclass of: PFC
notation: PFNA
type: Class

Elective Caesarian Section
definition: A caesarian section that was chosen by the mother but was not medically necessary.
subclass of: Caesarian Section
type: Class
type: QualityValue
notation: 19

parasites per microgram
notation: parasites/µL
type: SIO_000074

Platinum
type: Class
subclass of: Metal
definition: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) PLATINUM is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
notation: Pt

Unmarried
notation: 46
type: Class
type: QualityValue
subclass of: Marital Status
definition: Indicates a person not currently joined in a legally binding matrimonial union.

mono-benzyl phthalate
editorial note: Is this a repeat of MBP?
notation: mBzP
type: Class
subclass of: Phthalate

Cesium
notation: Cs
type: Class
subclass of: Metal
definition: A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.

counts per minute
notation: cpm
type: SIO_000074

(9Z)-hexadecenoic acid
notation: C161N7
type: Class
definition: A hexadecenoic acid with a cis-double bond at position C-9.
subclass of: Fatty Acid

Titanium
type: Class
subclass of: Metal
notation: Ti
definition: TITANIUM is a dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)

3-phenoxybenzoic acid
type: Class
subclass of: Metabolite
definition: A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides.

Household Appliance Count
subclass of: Housing Characteristic
type: QuantityVariable
type: Class
subclass of: SIO_000794
was approved by: PER-Jeanette-Stingone
definition: Total number of appliances that can be found in the home.

Interleukin-6
definition: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
subclass of: Protein
type: Class
notation: IL6

Red Blood Cell
subclass of: Blood Component
type: Class
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.

hour
type: SIO_000074
notation: h

Advanced Graduate Degree
definition: Having earned a pos-baccalaureate degree
type: Class
type: QualityValue
notation: 4
subclass of: Education

Delivery Characteristics
subclass of: StudyIndicator
type: Class
definition: Attributes related to the delivery of a child.

mono (7-COOH-2-methyloctyl) phthalate
subclass of: Phthalate
type: Class
notation: MCOMOP

Underweight
subclass of: Body Weight Quality
definition: BMI < 18.5
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
notation: 99
subclass of: Underweight/Normal
type: Class
type: QualityValue

Liquid Chromotography-Multistage Mass Spectrometery
subclass of: MassSpectrometry
type: Class

Some College
type: QualityValue
notation: 85
subclass of: Higher Education
type: Class
was approved by: PER-Jeanette-Stingone
definition: Indicates that a person has attended college but that they did not receive any degree.

byte
type: SIO_000074
notation: Byte

Matched Pair of Subjects
subclass of: SIO_000616
definition: A set of 2 subjects which result from a pairing process which assigns subject to a set based on a pairing rule/criteria
type: Class

SIO_001068
notation: 135
type: QualityValue

Medical History
definition: Medical History Indicator Class
subclass of: StudyIndicator
type: Class
was approved by: PER-Jeanette-Stingone

molal
notation: mol/kg
type: SIO_000074

Surface-Induced Dissociation (SID)
type: Class
subclass of: TandemMassSpectrometry

watt
notation: watt
type: SIO_000074

Cognitive Entity
type: Class
subclass of: Neurocognitive Assessment

picoliter
type: SIO_000074
notation: pl

Heptyl paraben
subclass of: Paraben
type: Class
notation: HePB

millimolar
notation: mM
type: SIO_000074

2, 2', 4, 4', 5, 6'-Hexabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE154
subclass of: Polybrominated Diphenyl Ether
type: Class

Barium
type: Class
notation: Ba
subclass of: Metal
definition: BARIUM is an element of the alkaline earth group of metals. It has an atomic symbol Ba, atomic number 56, and atomic weight 138. All of its acid-soluble salts are poisonous.

PCB153
subclass of: Polychlorobiphenyl
notation: PCB153
type: Class

Birthplace
definition: The place where a person was born.
type: QualityVariable
subclass of: Location
type: Class
subclass of: Demographic

Known Food Allergies
subclass of: Health Outcome
type: QualityVariable
type: Class

Trans-Nonachlor
subclass of: Organochlorine Compound
type: Class
notation: TNON

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
type: Class
notation: VOCPHE
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

Thallium
subclass of: Metal
notation: Tl
type: Class
definition: THALLIUM is a heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.

Common Era
subclass of: Relative Time
type: Class
definition: Common era time measurements are referenced against (in relation to) the beginning of the common era, 1 CE (or 1 AD).
equivalent class: Restriction
  has value: First Year of the Common Era
  on property: inRelationTo

eosinophilic esophagitis in remission
type: Class
subclass of: eosinophilic esophagitis
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: hasAttribute
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of less than 15 eosinophils per high-power field area, or 0.158 mm^2 (400x).

docosanoic acid
type: Class
definition: A straight-chain, C22, long-chain saturated fatty acid.
notation: C220
subclass of: Fatty Acid

thawed and hemolyzed (covers all three levels)
subclass of: SIO_001167
type: Class

Non-Spontaneous Preterm Birth
notation: 60
subclass of: Preterm Birth
type: Class
type: QualityValue

mono-(2-ethylhexyl) terephthalate
notation: MEHTP

Femur
subclass of: SIO_010046
type: Class

thousand parts per microgram
type: SIO_000074
notation: x103 µL

parts per quadrillion
type: SIO_000074
notation: ppq

Operating Room
notation: 171
definition: A room in a health care facility equipped for the performance of surgical operations and procedures.
type: Class
type: QualityValue
subclass of: Destination

Did Not Consume Alcohol
type: QualityValue
notation: 53
type: Class
subclass of: Alcohol Use

Lead
definition: LEAD is a soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.19, symbol Pb. (Dorland, 28th)
subclass of: Metal
type: Class
notation: Pb

mono (3-carboxypropyl) phthalate (multiple)
notation: MCPP
subclass of: Phthalate
type: Class

Prenatal Nonsmoker
subclass of: Non-smoker
definition: Could be a former smoker or a non-smoker, so neither should be encoded as the superclass.
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
type: Class
notation: 76
type: QualityValue

2, 4, 4'-Tribromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
notation: BDE28
type: Class
editorial note: To Do: align with CHEBI.

katal per liter
type: SIO_000074
notation: kat/l

Normal Weight
type: QualityValue
type: Class
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
subclass of: Body Weight Quality
subclass of: Underweight/Normal
notation: 61
definition: 18.5<=BMI<=25

Drinking Water
definition: Drinking Water
subclass of: Environmental Material
definition: Drinking water is water which may be consumed by humans with no adverse effects on their health.
type: Class

Environmental Exposure
was approved by: PER-Jeanette-Stingone
definition: EnvironmentalExposure Indicator Class
subclass of: StudyIndicator
type: Class
editorial note: may need to refine this name in order to clearly differentiate from environmental exposures measured within CHEAR. Perhaps ExternalEnvironmental Exposure. Ok for now but we may want to discuss.

MicroPEM
subclass of: Exposure Monitoring Instrument
definition: The MicroPEM device monitors individual exposures to very fine airborne particles—or particulate matter—at two sizes. PM10 has a diameter of less than 10 micrometers (PM10), which is approximately 1/30th the size of a human hair, and PM2.5, which at diameters of less than 2.5 micrometers, is even smaller.
type: Class
was approved by: PER-Jim-McCusker

Foster
subclass of: Non-Biological Relative
type: Class
definition: Fosterage, the practice of a family bringing up a child not their own, differs from adoption in that the child's parents, not the foster-parents, remain the acknowledged parents. In many modern western societies foster care can be organized by the state to care for children with troubled family backgrounds, usually on a temporary basis. In many pre-modern societies fosterage was a form of patronage, whereby influential families cemented political relationships by bringing up each other's children, similar to arranged marriages, also based on dynastic or alliance calculations.

Bisphenol A
type: Class
definition: 4, 4'-isopropylidenediphenol is a white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)
subclass of: Environmental Phenol
notation: BPA

Electrospray Ionization Mass Spectrometry
was approved by: PER-Jim-McCusker
type: Class
definition: Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.
subclass of: MassSpectrometry

Study Followup
subclass of: SIO_000417
type: Class
definition: A point in a study where data is gathered after the initial baseline.

T-Score
type: Class
definition: A method for converting an individual score into a standard form. While similar to a z-score, t-score is used when the conversion is made without knowledge of the population standard deviation and mean.
subclass of: STATO_0000569

milliliter per liter
notation: ml/l
type: SIO_000074

micrograms per meter cubed
type: SIO_000074
notation: µg/m3

Biological Sex
type: QualityVariable
type: Class
subclass of: Demographic

Arsenic Species
definition: A molecular entity with arsenic components.
type: Class
subclass of: Targeted Analyte

molar
notation: M
type: SIO_000074

Arsenobetaine
notation: Arsenobetaine
subclass of: Arsenic Species
type: Class

Never Smoked
type: QualityValue
type: Class
subclass of: Smoking Status
definition: The quality of never smoking in the past.
was approved by: PER-Jeanette-Stingone
notation: 56

Triclosan
subclass of: Environmental Phenol
type: Class
notation: TCS
definition: Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.

Metabolite
definition: A substance formed in or necessary for metabolism
type: Class
subclass of: Analyte

Landfill Proximity
was approved by: PER-Jeanette-Stingone
definition: How close a household is to a landfill.
type: QuantityVariable
subclass of: SIO_000041
type: Class
subclass of: Environmental Exposure

nanometer
type: SIO_000074
notation: nm

2-thoxothazlidne-4-carbxylic acid(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOCTTC

E-Cigarette Puffs Per Day
type: Class
subclass of: E-Cigarette Use
subclass of: SIO_000794
type: QuantityVariable

Homemaker
notation: 68
subclass of: Occupation
type: QualityValue
type: Class
definition: A person who manages a home as their main daily activity.

Interleukin-25
subclass of: Protein
type: Class
notation: IL17EIL25

Mercury
type: Class
definition: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
subclass of: Metal
notation: Hg

N-Acetyl-S-(trichlorovinyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: TCVMA
type: Class
subclass of: Volatile Organic Compound

microliter
notation: µl
type: SIO_000074

Entity
type: Class
subclass of: ScienceIndicator

Acculturation
definition: Acculturation explains the process of cultural change and psychological change that results following meeting between cultures. This metaclass contains all classes that measure this process.
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator

Gestational Age at Birth
equivalent class: Class
  intersection of: Gestational Age
  intersection of: Restriction
    on property: measuredAt
    all values from: Birth
definition: Describes how far along a pregnancy is, usually measured in weeks, as measured at birth.
subclass of: Gestational Age
type: Class

Seizures
definition: Seizures are an intermittent abnormality of the central nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures.
subclass of: Phenotype
type: Class
type: QualityValue
notation: 125

Unemployment
type: QualityValue
type: Class
definition: The state of not having a job.
notation: 67
subclass of: Occupation

Analysis
type: Class
subclass of: Analyte
definition: The value contains concentrations from the study sample

sievert
type: SIO_000074
notation: Sv

radian
notation: rad
type: SIO_000074

nanosievert
notation: nSv
type: SIO_000074

mild eosinophilic esophagitis
equivalent class: Restriction
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: hasAttribute
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
  on property: isPhenotypeOf
subclass of: eosinophilic esophagitis
type: Class
comment: Eosinophilic esophagitis is mild when a biopsy of the esophagus reveals a count of 15-25 eosinophils per high-power field area, or 0.158 mm^2 (400x).

Polymerase Chain Reaction
type: Class
subclass of: SIO_001007

millimeter
notation: mm
type: SIO_000074

Polygamous
notation: 45
type: QualityValue
definition: A type of living arrangement or mating system in which at least one member of a relationship has more than one mate.
subclass of: Marital Status
type: Class

hemoglobin measurement
subclass of: Concentration
type: Class

Polybrominated Diphenyl Ether
type: Class
subclass of: Targeted Analyte

Hemolyzed (covers all three levels) and contaminated
subclass of: SIO_001167
type: Class

Quit Smoking
notation: 82
type: Class
definition: Quit Smoking Cigarettes
type: QualityValue
subclass of: Previous Smoker

Single-Family House
definition: A residential building designed to hold one family.
notation: 175
subclass of: Residential Building
type: QualityValue
type: Class

N-Acetyl-S- (3, 4-dihydroxybutyl)-L-cysteine
notation: DHBMA
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Volatile Organic Compound

picomole
type: SIO_000074
notation: pmol

o-Xylene
notation: OXY
subclass of: Volatile Organic Compound
type: Class
definition: O-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)

eosinophils per high-power field
comment: A histological count of the eosinophils in a high-power microscopic field of view, or 0.158 mm^2 (x400).
type: Class
subclass of: SIO_000794

microeinstein per square meter per second
notation: µeinstein/sm2
type: SIO_000074

Paraben
type: Class
subclass of: Targeted Analyte

Grandfather
type: Class
definition: The father of your father or mother.
subclass of: Ancestor

millimole
type: SIO_000074
notation: mmol

kilogram per liter
notation: kg/L
type: SIO_000074

becquerel
notation: Bq
type: SIO_000074

Lymphocyte
subclass of: Leukocyte
definition: A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
type: Class

Cold Vapor Atomic Fluorescence Spectroscopy Instrument
type: Class
definition: Used in the measurement of trace amounts of volatile heavy metals such as mercury, cold vapour AFS makes use of the unique characteristic of mercury that allows vapour measurement at room temperature.
was approved by: PER-Jim-McCusker
subclass of: Atomic Fluorescence Spectroscopy Instrument

Targeted Sequencing
subclass of: Nucleic Acid Sequencing
definition: Nucleic acid sequencing that limits the scope of sequencing by filtering out portions of the nucleic acids that do not meet some criteria.
type: Class

Fast Food Consumption Frequency
type: Class
subclass of: Diet Quantity
type: QuantityVariable
definition: Frequency of Fast Food Consumption.
was approved by: PER-Jeanette-Stingone

p-Xylene*
type: Class
definition: P-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. Freezing point is 56°F. (USCG, 1999)
notation: PXY
subclass of: Volatile Organic Compound

monoethyl phthalate (DEP)
subclass of: Phthalate
type: Class
notation: MEP

Interleukin-31
type: Class
notation: IL31
subclass of: Protein

Socioeconomic Status Index
subclass of: Socioeconomic Status
type: QuantityVariable
definition: A measure of SES.
type: Class
editorial note: This is a specific index, derived from other variables. So, it should somehow be connected to this variables. Also, we may want to be more specific about the type of index that it is. Perhaps there should be a general SESIndex and then subclasses of specific measures?
subclass of: SIO_000052

thawed, hemolyzed (covers all three levels) and exposed to light
subclass of: SIO_001167
type: Class

SIO_010059
type: QualityValue
notation: 132

hertz
type: SIO_000074
notation: Hz

Organochlorine Compound
type: Class
subclass of: Targeted Analyte

Anemia
type: QualityValue
type: Class
subclass of: Phenotype
notation: 128
definition: A reduction in erythrocytes volume or hemoglobin concentration.

2, 4-Dichlorophenol
definition: 2, 4-dichlorophenol is a colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
notation: DCP24
subclass of: Environmental Phenol
type: Class

Daily E-Cigarette Use
type: Class
notation: 156
subclass of: E-Cigarette Use
type: QualityValue

Multiracial
subclass of: Non-White
was approved by: PER-Jeanette-Stingone
definition: Having ancestors of several or various races.
editorial note: Not part of current prov for Race. Should we remove this concept?
subclass of: Race
notation: 54
type: QualityValue
type: Class

absorbance unit
notation: AU
type: SIO_000074

pneumonia
type: QualityValue
type: Class
notation: 195
subclass of: DOID 850

Sibling
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Sibling
    intersection of: SIO_000485
subclass of: Relative
definition: One of two or more individuals having one or both parents in common. A male sibling is a brother, and a female sibling is a sister. In most societies throughout the world, siblings often grow up together, thereby facilitating the development of strong emotional bonds. The emotional bond between siblings is often complicated and is influenced by factors such as parental treatment, birth order, personality, and personal experiences outside the family. However, there are cases where siblings grow up in separate homes, in different environments.

Caesarian Section
notation: 20
subclass of: Route Of Delivery
subclass of: Pregnancy Characteristic
type: Class
definition: Caesarian Section Medical Procedure. One-third of pregnancies in the US end in C-Sections.
type: QualityValue

Chief Complaint
subclass of: Health Outcome
type: Class
type: QualityVariable

milliliter per cubic meter
type: SIO_000074
notation: ml/m3

mono-carboxy isononyl phthalate
notation: mCINP
type: Class
subclass of: Phthalate

Married
type: Class
notation: 37
type: QualityValue
definition: Indicates a person currently joined in a legally binding matrimonial union. Classify common law marriage as married. Includes married couples living together and not living together.
subclass of: Marital Status

Fast Food Consumption
type: Class
type: QualityValue
was approved by: PER-Jeanette-Stingone
subclass of: Fast Food Consumption Frequency
definition: Whether or not fast food is consumed.
notation: 16

Apartment
type: Class
notation: 196
subclass of: NCIT C86029
type: QualityValue

Social Affect + Restricted and Repetitive Behavior Total
definition: Total Standardized Autism Diagnostic Observation Schedule (ADOS) score.
type: QuantityVariable
type: Class
subclass of: CAO_01168

white blood cell count
type: Class
subclass of: SIO_000794

Bisphenol S
type: Class
subclass of: Environmental Phenol
notation: BPS

1-hydroxychrysene
type: Class
subclass of: PAH
notation: CHRY1

3-hydroxybenzo[c]-phenanthrene
type: Class
subclass of: PAH
notation: BCP3

Butyl paraben
definition: Butylparaben is a Standardized Chemical Allergen. The physiologic effect of butylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of butylparaben is Allergens.
type: Class
notation: BuPB
subclass of: Paraben

trans, trans -Muconic acid
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: MU

Vitamin D
subclass of: Diet and Nutrition
subclass of: Biomolecule
definition: Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body.
type: Class

SIO_000751
notation: 133
type: QualityValue

SpectraMax Plus 384 Microplate Reader
type: Class
definition: Get absorbance measurements from 190 to 1000 nm quickly for samples in test tubes, cuvettes, and 96- or 384-well microplates. The SpectraMax® Plus 384 Microplate Reader gives you walk-up convenience for both standard spectrophotometer and microplate reader applications on the same instrument. Monochromator wavelength selection saves you the time and trouble of ever having to change out filters. Typical applications for this powerful reader include DNA and RNA quantification, enzyme kinetic assays, and ELISA based assays. When your project is ready for high throughput, take advantage of StakMax® automated microplate handling compatibility for full robotic integration.
subclass of: Microplate Reader
was approved by: PER-Jim-McCusker

Spontaneous Caesarian Section
definition: Had a spontaneous caesarian section
was approved by: PER-Jeanette-Stingone
type: QualityValue
type: Class
subclass of: Caesarian Section
notation: 22

mono-isodecyl phthalate
type: Class
notation: mIDP
subclass of: Phthalate

Creatinine
subclass of: Targeted Analyte
notation: CRE
type: Class
definition: Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.

Broken Mitest
type: Class
subclass of: SIO_001167

microliter per kilogram
type: SIO_000074
notation: µl/kg

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
notation: HEMA2

Partial match
subclass of: SIO_001167
type: Class

femtomole
notation: fmol
type: SIO_000074

Specimen analyzed with less than normal quantity
type: Class
subclass of: SIO_001167

Language
subclass of: Acculturation
type: QualityVariable
editorial note: Needs to be rooted in sio
type: Class

Part Time Employment
type: Class
type: QualityValue
notation: 65
definition: Employment involving less than the standard or customary working time.
subclass of: Occupation

Cotinine (total)
editorial note: To Do: align with CHEBI.
notation: COTT
type: Class
subclass of: Tobacco Metabolite

micrograms per deciliter
notation: µg/dl
type: SIO_000074

Non-smoker
subclass of: Smoking Status
type: QualityValue
notation: 59
type: Class
definition: Doesn't smoke cigarettes.

pascal
type: SIO_000074
notation: Pa

type 2 diabetes mellitus
subclass of: DOID 9351
type: QualityValue
type: Class
notation: 181

millisecond
type: SIO_000074
notation: ms

volume percentage
notation: %(v/v)
type: SIO_000074

2, 2', 4, 4', 6-Pentabromodiphenyl ether
subclass of: Polybrominated Diphenyl Ether
type: Class
notation: BDE100
editorial note: To Do: align with CHEBI.

picomoles per milliliter
type: SIO_000074
notation: pmol/ml

Weight
subclass of: Anthropometry
definition: The resulting Force from the interaction between a person's Mass and Gravity.
subclass of: SIO_000279
was approved by: PER-Jeanette-Stingone
type: QuantityVariable
type: Class

Interleukin-23 subunit alpha
subclass of: Protein
notation: IL23
type: Class

Lymphotoxin-alpha
type: Class
notation: TNFB
subclass of: Protein

Valid measurement, results repeated and confirmed (0, 33)
subclass of: SIO_001167
type: Class

Concentration
type: QuantityVariable
type: Class
subclass of: Laboratory Result

milliliter
type: SIO_000074
notation: ml

Matrix metalloproteinase-9
notation: MMP9
subclass of: Protein
type: Class

Ethylbenzene
definition: Ethylbenzene is mainly used in the manufacture of styrene. Acute (short-term) exposure to ethylbenzene in humans results in respiratory effects, such as throat irritation and chest constriction, irritation of the eyes, and neurological effects such as dizziness. Chronic (long-term) exposure to ethylbenzene by inhalation in humans has shown conflicting results regarding its effects on the blood. Animal studies have reported effects on the blood, liver, and kidneys from chronic inhalation exposure to ethylbenzene. Limited information is available on the carcinogenic effects of ethylbenzene in humans. In a study by the National Toxicology Program (NTP), exposure to ethylbenzene by inhalation resulted in an increased incidence of kidney and testicular tumors in rats, and lung and liver tumors in mice. EPA has classified ethylbenzene as a Group D, not classifiable as to human carcinogenicity.
notation: EB
type: Class
subclass of: Volatile Organic Compound

Refractometer
was approved by: PER-Jim-McCusker
definition: A laboratory or field device for the measurement of an index of refraction (refractometry). The index of refraction is calculated from Snell's law while for mixtures, the index of refraction can be calculated from the composition of the material using several mixing rules such as the Gladstone–Dale relation and Lorentz–Lorenz equation.
type: Class
subclass of: PhysicalInstrument

Daily Smoker
type: Class
type: QualityValue
notation: 157
subclass of: Smoking Status

Electron Transfer Dissociation (ETD)
subclass of: TandemMassSpectrometry
type: Class

Gadolinium
definition: Gadolinium. An element of the rare earth family of metals. GADOLINIUM has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
type: Class
subclass of: Metal
notation: Gd

parts per thousand
type: SIO_000074
notation: ppth

Study Baseline
subclass of: SIO_000417
definition: Point in study set to initial point.
type: Class

Monoisopropyl phthalate
type: Class
subclass of: Phthalate
notation: MiPP

Hemolyzed (covers all three levels) and debris present
subclass of: SIO_001167
type: Class

Abnormal hemoglobin variant observed
subclass of: SIO_001167
type: Class

SIO_000980
notation: 107
type: QualityValue

2-amnothiazolne-4-carbxylic acid(ng/mL)
type: Class
editorial note: To Do: align with CHEBI.
notation: VOCATC
subclass of: Volatile Organic Compound

minute
notation: min
type: SIO_000074

Income 5001 to 15000
definition: Personal or family annual income bwtween $5,001 and $15,000
notation: 160
type: QualityValue
subclass of: Household Income
type: Class

Analyte
type: Class
subclass of: SIO_010004

gamma-hexachlorocyclohexane
type: Class
subclass of: Organochlorine Compound
notation: GHCH

Benzophenone
subclass of: Targeted Analyte
type: Class

No Anti Malarial Use
subclass of: Prescription Medication and Dietary Supplements
notation: 140
type: Class
type: QualityValue

milliampere
type: SIO_000074
notation: mA

4, 4′-(1, 4-Phenylenediisopropylidene)bisphenol
notation: BPP

(15Z)-tetracosenoic acid
type: Class
notation: C241N9
definition: A tetracosenoic acid having a cis-double bond at position 15.
subclass of: Fatty Acid

Medication
notation: 142
definition: A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product.
subclass of: Prescription Medication and Dietary Supplements
type: QualityVariable
type: Class

Saliva
type: Class
definition: A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. [database_cross_reference: http://en.wikipedia.org/wiki/Saliva][database_cross_reference: GO:0046541]
subclass of: Bodily Fluid

Failed positive control
subclass of: SIO_001167
type: Class

Domestic Partnership
type: Class
type: QualityValue
notation: 42
definition: Indicates a person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered.
subclass of: Unmarried

Abdomen
type: Class
subclass of: SIO_010046

base pair
type: SIO_000074
notation: bp

valid measurement
type: Class
subclass of: SIO_001167

Doctorate Degree
subclass of: Some Postgraduate
type: Class
definition: The Doctor's Degree is the highest award a student can earn for graduate study. The doctor's degree classification includes such degrees in any field.
type: QualityValue
notation: 144
subclass of: Higher Education

Planned Caesarian Section
type: Class
definition: Planned caesarian section.
notation: 18
was approved by: PER-Jeanette-Stingone
subclass of: Caesarian Section
type: QualityValue

Obese
subclass of: Restriction
  some values from: Restriction
    on property: hasAttribute
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
  on property: isAttributeOf
notation: 63
type: QualityValue
subclass of: Body Weight Quality
type: Class

Roentgen equivalent man
type: SIO_000074
notation: rem

Malaria
subclass of: Health Outcome
type: QualityValue
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
notation: 121
subclass of: SIO_010299
type: Class

Beginning
subclass of: Restriction
  on property: hasValue
  has value: 1
type: Class
definition: A time relative to the beginning of an event
subclass of: Relative Time

Household
subclass of: Housing Characteristic
subclass of: SIO_001064
type: Class
definition: A household consists of one or more people who live in the same dwelling and also share meals or living accommodation, and may consist of a single family or some other grouping of people. A single dwelling will be considered to contain multiple households if either meals or living space are not shared. The household is the basic unit of analysis in many social, microeconomic and government models, and is important to the fields of economics and inheritance.

watt per meter kelvin
type: SIO_000074
notation: W/mK

dehydroepiandrosterone sulfate
definition: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.
subclass of: Biological Response
subclass of: Metabolite
type: Class

Panel change
subclass of: SIO_001167
type: Class

Biological Relative
type: Class
definition: Being from the same biological kinship as another person. In that aspect, consanguinity is the quality of being descended from the same ancestor as another person.
subclass of: Relative

Whole Blood
subclass of: Bodily Fluid
definition: A fluid that is composed of blood plasma and erythrocytes. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Blood][database_cross_reference: https://github.com/obophenotype/uberon/issues/9][database_cross_reference: FMA:9670]
type: Class

mono(7-carboxyheptyl)phthalate
subclass of: Phthalate
type: Class
notation: mCHpP

6-hydroxychrysene
type: Class
notation: CHRY6
subclass of: PAH

Hospitalization
definition: Admission to a hospital
type: Class
subclass of: SIO_001024
notation: 104
subclass of: Hospital Utilization
type: QualityValue

Some Middle School
subclass of: High School or Less
notation: 90
definition: Attended Some Middle School
was approved by: PER-Jeanette-Stingone
type: QualityValue
type: Class

mono-2-heptyl phthalate
subclass of: Phthalate
notation: mHpP
type: Class

Perfluoro-n-pentanoic acid
notation: PFPeA
subclass of: PFC
type: Class

RNA
subclass of: Macromolecule
type: Class

High-Performance Liquid Chromatography-Mass Spectrometry
definition: Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. Therefore, LC-MS may be applied in a wide range of sectors including biotechnology, environment monitoring, food processing, and pharmaceutical, agrochemical, and cosmetic industries.
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class
subclass of: High-Performance Liquid Chromatography
subclass of: Liquid Chromatography–Mass Spectrometer

Tobacco Smoke Exposure
subclass of: Environmental Exposure
notation: 98
type: Class
type: QualityValue

attomole
type: SIO_000074
notation: amol

Value greater than ULOQ
subclass of: SIO_001167
type: Class

Parent
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Child
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
type: Class
subclass of: Ancestor
definition: A parent is the caretaker of a child (where "child" refers to offspring, not necessarily age). A biological parent is a person whose gamete resulted in a child, a male through the sperm, and a female through the ovum. Parents are first-degree relatives and have 50% genetic meet. A female can also become a parent through surrogacy. Some parents may be adoptive parents, who nurture and raise an offspring, but are not actually biologically related to the child. Orphans without adoptive parents can be raised by their grandparents or other family members.
was approved by: PER-Jeanette-Stingone

SIO_000982
type: QualityValue
notation: 106

Propyl paraben
type: Class
notation: PrPB
definition: Propylparaben is a Standardized Chemical Allergen. The physiologic effect of propylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of propylparaben is Allergens.
subclass of: Paraben

nutrition intake
definition: Nutrition intake is the process of taking in of nutrients, especially by eating or drinking, considered in relation to the body’s dietary needs.
subclass of: Diet and Nutrition
type: Class
type: QualityVariable

Sample older than 2 weeks
type: Class
subclass of: SIO_001167

Teenager
subclass of: Demographic
type: Class
notation: 137
type: QualityValue
was approved by: PER-Jeanette-Stingone
subclass of: Developmental Quality
definition: An individual between the ages of 13 and 19.

Antimalarial
notation: 120
type: QualityValue
type: Class
subclass of: Medication
definition: A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.

Fever
subclass of: Phenotype
notation: 123
type: QualityValue
definition: Elevated body temperature due to failed thermoregulation.
type: Class

einstein per square meter per second
notation: einstein/sm2
type: SIO_000074

enzyme-linked immunosorbent assay (ELISA)
type: Class
subclass of: Immunoassay
definition: ELISA is an immunoassay that uses antibodies and color change to identify a substance (Wikipedia)

Body Weight Quality
definition: A categorization of body mass relative to the height, as defined using Body Mass Index.
type: Class
subclass of: SIO_000005
subclass of: Anthropometry

Atomic Fluorescence Spectroscopy Instrument
definition: a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light.
was approved by: PER-Jim-McCusker
type: Class
subclass of: PhysicalInstrument

Pregnancy Complication
subclass of: Pregnancy Characteristic
notation: 75
type: QualityValue
type: Class

Obvious coarse debris
subclass of: SIO_001167
type: Class

volt per meter
notation: V/m
type: SIO_000074

Health Maintenance Organization Insurance
type: QualityValue
type: Class
notation: 49
subclass of: Insurance

Inorganic Mercury (Hg2+)
subclass of: Mercury Species
notation: Hg2
type: Class

Phenylglyoxylic acid(ng/mL)
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: VOCPHG

nanograms per liter
notation: ng/L
type: SIO_000074

Canned Food Consumption
type: QualityValue
type: Class
notation: 9
definition: Whether or not canned food is consumed.
subclass of: Canned Food Consumption Frequency
was approved by: PER-Jeanette-Stingone

Health Outcome
subclass of: StudyIndicator
type: Class

mono-isopropyl phthalate
editorial note: Duplicate of MiPP?
subclass of: Phthalate
type: Class
notation: mIPrP

Atomic Absorption Spectroscopy
type: Class
subclass of: Atomic Spectroscopy

Torn, perforated screen
subclass of: SIO_001167
type: Class

Value above LOD but below LLOQ
subclass of: SIO_001167
type: Class

Gas Chromatographer-Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
subclass of: Tandem Mass Spectrometer
definition: MS/MS is the combination of two mass analyzers in one mass spec instrument.
subclass of: Gas Chromatographer–Mass Spectrometer
type: Class

Developmental Quality
type: QualityVariable
type: Class
definition: Refers to which stage of development a person is in.
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000475

Technical Post Junior College
type: Class
notation: 93
was approved by: PER-Jeanette-Stingone
subclass of: Technical School
type: QualityValue
definition: Attended a Technical Post Junior College
subclass of: Education

PCB52
subclass of: Polychlorobiphenyl
type: Class
notation: PCB52

2-hydroxybenzo[c]-phenanthrene
type: Class
notation: BCP2
subclass of: PAH

mono (6-COOH-2-methylheptyl) phthalate
subclass of: Phthalate
type: Class
notation: MCOMHP

9-hydroxyfluorene
type: Class
subclass of: PAH
notation: FLUO9

Steroid Treatment form of Medical Therapy
was approved by: PER-Jeanette-Stingone
subclass of: Medical Therapy Procedure
notation: 28
type: QualityValue
definition: Had a form of treatment which uses steroids.
type: Class

Esophagus
subclass of: SIO_010003
type: Class

Fatty Acid
type: Class
definition: Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax.
subclass of: Targeted Analyte

Interleukin-4
type: Class
subclass of: Protein
notation: IL4

count per nanomolar second
type: SIO_000074
notation: 1/nMs

Private Insurance or Self Pay
type: QualityValue
type: Class
subclass of: Insurance
notation: 51

Head Of Household
was approved by: PER-Jeanette-Stingone
subclass of: Demographic
definition: The Person is the head of Household
definition: Head of Household is a filing status for individual United States taxpayers. To use the Head of Household filing status, a taxpayer must: (1) Be unmarried or considered unmarried at the end of the year (2) Have paid more than half the cost of keeping up a home for the tax year (either one's own home or the home of a qualifying parent) (3) Usually have a qualifying person who lived with the head in the home for more than half of the tax year unless the qualifying person is a dependent parent.
subclass of: SIO_000016
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Household
label: Head of Household
type: Class

Interleukin-10
definition: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
subclass of: Protein
type: Class
notation: IL10

Metalloproteinase inhibitor 1
subclass of: Protein
notation: TIMP1
type: Class

parts per million
notation: ppm
type: SIO_000074

gram
type: SIO_000074
notation: g

Absorbance Reader
type: Class
definition: Absorbance readers are used for assays such as ELISA assays, protein and nucleic acid quantification or enzyme activity assays. A light source illuminates the sample using a specific wavelength (selected by an optical filter, or a monochromator), and a light detector located on the other side of the well measures how much of the initial (100%) light is transmitted through the sample: the amount of transmitted light will typically be related to the concentration of the molecule of interest.
was approved by: PER-Jim-McCusker
subclass of: Microplate Reader

Tibia
type: Class
definition: The major preaxial endochondral bone in the posterior zeugopod.
subclass of: SIO_010046

Third Trimester
subclass of: SIO_000417
definition: From 29 weeks through 40 weeks.
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: From Conception

Diet and Nutrition
definition: Diet and Nutrition Indicator
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class

beta-hexachlorocyclohexane
notation: BHCH
type: Class
subclass of: Organochlorine Compound

adrenic acid
type: Class
subclass of: Fatty Acid
notation: C224N6

Birth Cohort Study
type: Class
subclass of: CohortStudy

degree Fahrenheit
notation: F
type: SIO_000074

3-Chlorophenol
subclass of: Environmental Phenol
type: Class
definition: PHYSICAL DESCRIPTION: White crystals with an odor of phenol. Sinks in and slowly dissolves in water. (NTP, 1992)
notation: MCP3

Copper
notation: Cu
definition: COPPER is a heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
type: Class
subclass of: Metal

Interleukin-5
notation: IL5
type: Class
subclass of: Protein

C-C motif chemokine 20
subclass of: Protein
notation: MIP3A
type: Class

72 kDa type IV collagenase
notation: MMP2
type: Class
notation: IL33
label: Interleukin-33
subclass of: Protein

Zinc
subclass of: Metal
type: Class
notation: Zn
definition: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.

Perfluroundecanoic acid
notation: PFUNDA
type: Class
subclass of: PFC

Floor Type
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
subclass of: SIO_000004
definition: Type of material that makes up the floor.
type: QualityVariable

neuron
type: Class
subclass of: Cell

Diet Quantity
type: Class
subclass of: Diet and Nutrition
editorial note: What differentiated diet from nutrition? That is why is this needed since we have the DietAndNutrition Class
subclass of: SIO_000052
type: QuantityVariable
definition: A quantity relating to diet and nutrition.
was approved by: PER-Jeanette-Stingone

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
type: Class
subclass of: Inductively Coupled Plasma Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: A tandem mass spectrometer consisting of two quadrupole mass analyzers in series, with a (non-mass-resolving) radio frequency (RF)–only quadrupole between them to act as a cell for collision-induced dissociation.

milligram
notation: mg
type: SIO_000074

Interleukin-27 subunit alpha
notation: IL27
subclass of: Protein
type: Class

Lithium
type: Class
subclass of: Metal
notation: Li
definition: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.

Occupation
was approved by: PER-Jeanette-Stingone
subclass of: Socioeconomic Status
subclass of: Demographic
definition: An individual attribute that is the usual or principal work or business of an individual.
subclass of: SIO_000016
type: QualityVariable
type: Class

Cis-Nonachlor
notation: CNON
type: Class
subclass of: Organochlorine Compound

Clinical Measurement
definition: A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation.
type: Class
subclass of: Physical and Mental Assessment

tetracosanoic acid
definition: A C24 straight-chain saturated fatty acid.
subclass of: Fatty Acid
notation: C240
type: Class

N-Acetyl-S- (2-carboxyethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: CEMA

microcurie
type: SIO_000074
notation: µCi

mono-carboxy isooctyl phthalate
type: Class
notation: mCIOP
subclass of: Phthalate

Education Grade 7
definition: Finished grade 7
type: Class
notation: 119
type: QualityValue
subclass of: Some Middle School

N-Ethyl Perfluorooctane sulfonamido acetic acid
notation: NETFOSAA

Phenylglyoxylic acid
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: PGA

N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
type: Class
notation: MHBMA2
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.

Liquid Chromatography–Mass Spectrometer
subclass of: Liquid Chromatography Instrument
definition: An analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin.
subclass of: Mass Spectrometer
type: Class
was approved by: PER-Jim-McCusker

Hydroxycotinine
notation: HCOT
subclass of: Tobacco Metabolite
notation: HCOTT
type: Class
label: Hydroxycotinine (total)

HPLC with Fluorescence Level Detector
definition: HPLC paired with a Fluorescence Level Detector. Fluorescence spectroscopy (also known as fluorometry or spectrofluorometry) is a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light. A complementary technique is absorption spectroscopy. In the special case of single molecule fluorescence spectroscopy, intensity fluctuations from the emitted light are measured from either single fluorophores, or pairs of fluorophores.
subclass of: High-Performance Liquid Chromatography
type: Class

centiMorgan
notation: cM
type: SIO_000074

Ultra High Performance Liquid Chromatography Instrument
type: Class
definition: Modern HPLC systems have been improved to work at much higher pressures, and therefore are able to use much smaller particle sizes in the columns (<2 μm). These "Ultra High Performance Liquid Chromatography" systems or UHPLCs can work at up to 120 MPa (17, 405 lbf/in^2), or about 1200 atmospheres.
was approved by: PER-Jim-McCusker
subclass of: High-Performance Liquid Chromatography

Mono-2-(carboxymethyl) hexyl phthalate
subclass of: Phthalate
type: Class
notation: MCMHP

Income More Than 120000
subclass of: Household Income
type: QualityValue
definition: Personal or family annual income greater than $120,000
type: Class
notation: 166

Smoker
notation: 105
definition: The quality of smoking cigarettes.
type: QualityValue
type: Class
subclass of: Smoking Status

Technical School
notation: 96
was approved by: PER-Jeanette-Stingone
type: QualityValue
definition: Attended a Technical School.
subclass of: Education
type: Class

nanomole
type: SIO_000074
notation: nmol

Interleukin-1 beta
type: Class
definition: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
subclass of: Protein
notation: IL1B

Carbon Tetrachloride
notation: CTET
definition: CARBON TETRACHLORIDE is a solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
type: Class
subclass of: Volatile Organic Compound

m-Xylene*
type: Class
definition: M-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
notation: MXY
subclass of: Volatile Organic Compound

Biospecimen
type: Class
subclass of: SIO_010412
definition: A biological laboratory specimen held by a biorepository for research. Such a specimen would be taken by sampling so as to be representative of any other specimen taken from the source of the specimen. When biological specimens are stored, ideally they remain equivalent to freshly-collected specimens for the purposes of research.

Haptoglobin
notation: HAPTOGLOBIN
type: Class
subclass of: Protein

Adopted
subclass of: Non-Biological Relative
definition: Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents, and, in so doing, permanently transfers all rights and responsibilities, along with filiation, from the biological parent or parents.
type: Class

N-Acel-S-(2, 2-Dichlorvinyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: VOC2DC

Alkyl Phosphate Pesticide Metabolite
type: Class
subclass of: Targeted Analyte

Non-ecigarette user
notation: 199
definition: Doesn't use e-cigarettes.
type: Class
type: QualityValue
subclass of: Smoking Status

count per molar
type: SIO_000074
notation: 1/M

2, 2', 4, 4'-tetrahydroxybenzophenone
notation: BP2

Graduated From High School
definition: The quality of having graduated from High School
type: QualityValue
notation: 32
type: Class
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone

Oxybenzone
notation: OXB
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
subclass of: Volatile Organic Compound
type: Class

Perfluorooctanesulfonic acid
definition: Perfluoroalkyls are stable, synthetic chemicals. Perfluoroalkyls are unique because they repel oil, grease, and water. The two perfluoroalkyls made in the largest amounts in the U. S. areperflurooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Perfluoroalkyls have been used in surface protection products such as carpet and clothing treatments and coating for paper and cardboard packaging. They have also been used in fire-fighting foams.
type: Class
notation: PFOS
subclass of: PFC

compound eye retinal cell
subclass of: Cell
type: Class

Histidine-rich protein PFHRP-II
subclass of: Protein
type: Class

kelvin
notation: K
type: SIO_000074

type 1 diabetes mellitus
notation: 180
type: Class
type: QualityValue
subclass of: DOID 9351

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: GAMA
type: Class

Specimen analyzed with less than usual dilution
subclass of: SIO_001167
type: Class

mono-isobutyl phthalate (DiBP)
notation: MiBP
subclass of: Phthalate
type: Class

Laboratory Result
subclass of: Indicator
definition: A measurement taken on a sample.
type: Class

electronvolt
notation: eV
type: SIO_000074

Dilution required
subclass of: SIO_001167
type: Class

Nicotine-N-oxide
notation: NICO
type: Class
subclass of: Tobacco Metabolite

Nervous System
type: Class
definition: The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior
subclass of: SIO_010003

kilovolt
type: SIO_000074
notation: kV

Pregnancy Characteristic
subclass of: StudyIndicator
type: Class
was approved by: PER-Jeanette-Stingone
definition: Pregnancy Characteristic Indicator Class

Tetrachloroethene
definition: TETRACHLOROETHYLENE is a chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
subclass of: Volatile Organic Compound
type: Class
notation: TCE

SIO_010048
notation: 111
type: QualityValue

Boron
definition: A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY.
subclass of: Metal
notation: B
type: Class

Moderately hemolyzed
subclass of: SIO_001167
type: Class

Before
type: Class
subclass of: Relative Time
definition: A negative index of a time measurement in relation to a reference event. A conventional time measurement can be generated from a before time measurement by duplicating the measurement, reversing the sign of the value, and removing the "Before" class.

Insurance
type: QualityVariable
type: Class
subclass of: Socioeconomic Status
subclass of: Healthcare Access

Liquid Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: A separation technique in which the mobile phase is a liquid. It can be carried out either in a column or a plane. Present day liquid chromatography that generally utilizes very small packing particles and a relatively high pressure is referred to as high performance liquid chromatography (HPLC).
type: Class
subclass of: Chromatography Instrument

Z-Score
subclass of: Anthropometry
definition: A z-score (also known as z-value, standard score, or normal score) is a measure of the divergence of an individual experimental result from the most probable result, the mean. Z is expressed in terms of the number of standard deviations from the mean value.
type: Class

microunits per milliliter
notation: µU/mL
type: SIO_000074

Total nicotine
type: Class
editorial note: Duplicate of NIC?
subclass of: Tobacco Metabolite
notation: TNIC

Trunk
type: Class
definition: Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present.
subclass of: SIO_010046

hypertension
type: Class
type: QualityValue
notation: 178
subclass of: DOID_0050828

In Vitro Fertilization
type: QualityValue
notation: 50
subclass of: Assisted Reproductive Therapy
type: Class

N-Acetyl-S-(phenyl)-L-cysteine
notation: PMA
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

N-A-S-(3-hydrxprpl-1-metl)-L-cys(ng/mL)
notation: VOCPMM
editorial note: To Do: align with CHEBI.
type: Class
subclass of: Volatile Organic Compound

N-Ace-S-(dimethylphenyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCDPM
type: Class

Metal
type: Class
definition: For environmental purposes, HHEAR metals are metals and metalliods, as originally defined in CHEAR.
subclass of: Element

Perfluorobutanoic acid
type: Class
subclass of: PFC
notation: PFBA

all-cis-icosa-8, 11, 14-trienoic acid
definition: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.
type: Class
subclass of: Fatty Acid
notation: C203N6

disintegrations per second
type: SIO_000074
notation: dps

2-Methylhippuric acid (ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOC2MH

2, 4'-DDT
notation: OPDDT
type: Class
subclass of: Organochlorine Compound

Income 50001 to 75000
type: QualityValue
type: Class
definition: Personal or family annual income bwtween $50,001 and $75,000
notation: 163
subclass of: Household Income

4, 4'-DDE
type: Class
subclass of: Organochlorine Compound
notation: PPDDE

Caregiver
definition: a paid or unpaid and without formal training member of a person's social network who helps them with activities of daily living. Caregiving is most commonly used to address impairments related to old age, disability, a disease, or a mental disorder.
subclass of: Demographic
subclass of: SIO_000016
type: Class

Cerebrospinal fluid
definition: A clear, colorless fluid that is found in the brain and spinal cord.
subclass of: SIO_010046
type: Class

Cyclohexane-1, 2-dicarboxylic acid mono carboxyisooctyl ester (DINCH)
notation: MCOCH

Not Current Student
subclass of: SIO_001326
type: Class
notation: 141
type: QualityValue
definition: The state of an individual not currently engaged in educational activity as a pupil.

birthing
type: Class
subclass of: Birth Outcome

Collection Date of Sample
definition: Collection Date of Sample
type: Class
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
subclass of: SIO_000417

mebibyte
notation: MiB
type: SIO_000074

Hemolyzed (covers all three levels), lipemic, and icteric
subclass of: SIO_001167
type: Class

micromole per liter
type: SIO_000074
notation: µmol/L

Cadmium
type: Class
subclass of: Metal
definition: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.
notation: Cd

2, 2', 4'-Tribromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE17
type: Class
subclass of: Polybrominated Diphenyl Ether

Mental Health
definition: Mental Health Indicator
subclass of: Physical and Mental Assessment
type: Class
was approved by: PER-Jeanette-Stingone

Active Smoker
notation: 2
type: Class
type: QualityValue
editorial note: How is this different from "smoker'?
definition: The quality of actively smoking.
subclass of: Smoking Status

Mitest not capped
subclass of: SIO_001167
type: Class

DNA
type: Class
subclass of: Macromolecule

N-Acetyl-S-(benzyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: BMA
type: Class

Bisulfite Pyrosequencing
type: Class
subclass of: Nucleic Acid Sequencing

Genotype
subclass of: Medical History
type: Class

Analysis Mode
type: Class
type: QualityVariable
subclass of: SampleIndicator
definition: Analysis Mode

4, 4'-(hexafluoroisopropylidene)-dephenol
notation: BPAF

Personal Product Use
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class
definition: Personal Product Use Indicator Class

4, 4'-DDT
type: Class
notation: PPDDT
subclass of: Organochlorine Compound

2, 2', 4, 4', 5, 5'-Hexabromodiphenyl ether
notation: BDE153
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether

Sleep Characterisitic
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Sleep Characterisitics Indicator Class
type: Class

N-ac-S-(2-carbmo-2-hydxel)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCGAM
type: Class

Patella
subclass of: SIO_010046
type: Class
definition: The patella, also known as the knee cap or kneepan, is the largest sesamoid bone in the human body. The primary functional role of the patella is knee extension. The patella has convergently evolved in placental mammals and birds; marsupials have only rudimentary, non-ossified patellae. In more primitive tetrapods, including living amphibians and reptiles, the muscle tendons from the upper leg are attached directly to the tibia, and the patella is not present. See also: fabella.

Liquid Chromotography -tandem mass spectrometry
type: Class
subclass of: MassSpectrometry

Cyclohexane-1, 2-dicarboxylic acid mono hydroxyisononyl ester (DINCH)
notation: MHNCH

Collision-Induced Dissociation (CID)
type: Class
subclass of: TandemMassSpectrometry

Tobacco Metabolite
subclass of: Targeted Analyte
type: Class

kibibyte
type: SIO_000074
notation: KiB

dimethylthiophosphate
notation: DMTP
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.
type: Class

kilogram per meter
notation: kg/m
type: SIO_000074

1-hydroxyphenanthrene
type: Class
notation: PHEN1
subclass of: PAH

Coma
definition: Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli.
type: Class
notation: 124
subclass of: Phenotype
type: QualityValue

Nucleic Acid Sequencing
subclass of: SIO_001007
type: Class

N-Acetyl-S-(1, 2-dichlorovinyl)-L-cysteine
type: Class
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: DCVMA12

cyclic peptide
subclass of: Metabolite
type: Class
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
subclass of: Biological Response

Chromium
definition: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002, 1985), chromium and some of its compounds have been listed as known carcinogens.
type: Class
notation: Cr
subclass of: Metal

Severe Malarial Anemia
type: Class
type: QualityValue
definition: In holoendemic transmission areas, Severe Malarial Anemia (SMA) is the primary clinical manifestation of severe childhood malaria, with cerebral malaria occurring only in rare cases. Mortality rates from SMA can exceed 30% in pediatric populations residing in holoendemic transmission areas. The pathophysiological processes that contribute to SMA involve direct and indirect destruction of parasitized and non-parasitized red blood cells (RBCs), inefficient and/or suppression of erythropoiesis, and dyserythropoiesis.
subclass of: Anemia
notation: 127

Grandmother
subclass of: Ancestor
definition: The mother of your father or mother.
type: Class
type: QualityValue
notation: 190

Cotinine
definition: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
notation: COT
subclass of: Tobacco Metabolite
type: Class

cells per milliliter
type: SIO_000074
notation: cells per ml

Oral Health
subclass of: StudyIndicator
type: Class
was approved by: PER-Jeanette-Stingone
definition: Oral Health Indicator Class

colony forming unit
type: SIO_000074
notation: cfu

alpha-hexachlorocyclohexane
notation: AHCH
type: Class
subclass of: Organochlorine Compound

Magnesium
definition: An element with atomic symbol Mg, atomic number 12, and atomic weight 24.3. Magnesium is an alkaline earth metal and is important to bone structure in human physiology.
notation: Mg
subclass of: Metal
type: Class

ampere
notation: A
type: SIO_000074

Neurocognitive Assessment
type: Class
subclass of: Physical and Mental Assessment

picometer
notation: pm
type: SIO_000074

Gravimetric Analysis Instrument
was approved by: PER-Jim-McCusker
type: Class
subclass of: PhysicalInstrument
definition: Gravimetric analysis describes a set of methods used in analytical chemistry for the quantitative determination of an analyte (the ion being analyzed) based on its mass. The principle behind this type of analysis is that once an ion's mass has been determined as a unique compound, that known measurement can then be used to determine the same analyte's mass in a mixture, as long as the relative quantities of the other constituents are known.

mono-(2-ethyl-5-carboxypentyl) phthalate
notation: mECPP
editorial note: Duplicate of MCEPP?
subclass of: Phthalate
type: Class

3, 4-Dihydroxy-benzoic acid methyl ester
subclass of: Environmental Phenol
notation: OHMeP
type: Class

N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: AAMA

Colorimetric Assay
subclass of: SIO_001007
type: Class

megabasepair
notation: Mb
type: SIO_000074

dimethylphosphate
notation: DMP
type: Class
subclass of: Alkyl Phosphate Pesticide Metabolite
editorial note: To Do: align with CHEBI.

siemens
type: SIO_000074
notation: 1/AV

Gold
definition: GOLD is a yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
notation: Au
type: Class
subclass of: Metal

millisievert
notation: mSv
type: SIO_000074

First Year of the Common Era
type: NamedIndividual

Phthalate
type: Class
subclass of: Targeted Analyte

magnetic flux density unit
type: SIO_000074
notation: MFDU

Religion
definition: Religious Belief
type: QualityVariable
subclass of: Demographic
type: Class

square millimeter
notation: mm2
type: SIO_000074

Aligent 8800 Triple Quadrupole ICP-MS
was approved by: PER-Jim-McCusker
subclass of: Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
type: Class

N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
subclass of: Volatile Organic Compound
type: Class
editorial note: To Do: align with CHEBI.
notation: MHBMA1

Residential Building
subclass of: Housing Characteristic
type: Class
type: QualityVariable
type: QualityValue
notation: 154

Red blood cells present
type: Class
subclass of: SIO_001167

Feces
definition: Portion of semisolid bodily waste discharged through the anus[MW, modified] [database_cross_reference: http://en.wikipedia.org/wiki/Feces][database_cross_reference: http://www.merriam-webster.com/dictionary/feces]
type: Class
subclass of: Biospecimen

Prenatal Vitamin Use
definition: Prenatal vitamins are supplements that contain daily vitamins and minerals needed by mothers before and during pregnancy.
notation: 149
type: QualityValue
type: Class
subclass of: MAXO_00001018

Screening
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
definition: The time period during which a screening process is used to determine the inclusion of a subject in a study.
type: Class

milliliter per kilogram
notation: ml/kg
type: SIO_000074

Perfluorobutanesulfonic acid
notation: PFBS
subclass of: PFC
type: Class

watt per square meter
type: SIO_000074
notation: W/m2

Cis-Chlordane
type: Class
notation: CCHL
subclass of: Organochlorine Compound

Developmental Disorder of Mental Health
subclass of: Disease
type: Class

electric field strength unit
notation: Efs
type: SIO_000074

Mercapturic acids of 1, 3-butadiene
subclass of: Tobacco Metabolite
notation: HEMA
type: Class

No preservative added
subclass of: SIO_001167
type: Class

all-cis-docosa-4, 7, 10, 13, 16, 19-hexaenoic acid
definition: A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
subclass of: Fatty Acid
notation: C226N3
type: Class

2, 2', 3, 3', 4, 4', 5, 5', 6, 6'-Decabromodiphenyl ether
type: Class
notation: BDE209
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether

Granulocyte-macrophage colony-stimulating factor
notation: GMCSF
type: Class
subclass of: Protein

Benzyl paraben
notation: BzPB
subclass of: Paraben
definition: Benzylparaben is a Standardized Chemical Allergen. The physiologic effect of benzylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of benzylparaben is Allergens.
type: Class

Leptin
definition: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.
type: Class
subclass of: Protein
subclass of: Metabolite

Physical and Mental Assessment
definition: Physical and Mental Assessments Indicator Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class

Hospital Readmissions
subclass of: Hospital Utilization
subclass of: SIO_000794
definition: An episode when a patient who had been discharged from a hospital is admitted again within a specified time interval.
type: Class

(7Z, 10Z, 13Z, 16Z, 19Z)-docosapentaenoic acid
type: Class
definition: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.
notation: C225N3
subclass of: Fatty Acid

Process
type: Class
subclass of: ScienceIndicator

Separated
notation: 41
definition: Indicates a person living apart from his/her spouse by legal arrangement.
subclass of: Married
type: QualityValue
type: Class

pre-eclampsia
subclass of: DOID_0050828
notation: 177
type: QualityValue
type: Class

2-Thioxothiazolidine-4-carboxylic acid
subclass of: Volatile Organic Compound
notation: TTCA
editorial note: To Do: align with CHEBI.
type: Class

Relative
was approved by: PER-Jeanette-Stingone
definition: Broadly, kinship patterns may be considered to include people related by both descent – i.e. social relations during development – and by marriage. Human kinship relations through marriage are commonly called "affinity" in contrast to the relationships that arise in one's group of origin, which may be called one's descent group. In some cultures, kinship relationships may be considered to extend out to people an individual has economic or political relationships with, or other forms of social connections. Within a culture, some descent groups may be considered to lead back to gods or animal ancestors (totems). This may be conceived of on a more or less literal basis.
subclass of: Restriction
  all values from: Class
    intersection of: Restriction
      all values from: Relative
      on property: hasRole
    intersection of: SIO_000485
  on property: inRelationTo
subclass of: SIO_000016
type: Class
subclass of: Demographic

2, 2', 3, 4, 4'-Pentabromodiphenyl ether
notation: BDE85
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Childhood Followup
definition: A point in a study that occurs after the initial baseline of the study and occurs during the study subject's childhood period.
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
subclass of: SIO_000417
type: Class
subclass of: Study Followup

1-hydroxybenzo[c]-phenanthrene
type: Class
subclass of: PAH
notation: BCP1

Interleukin-15
subclass of: Protein
type: Class
notation: IL15

steradian
notation: sr
type: SIO_000074

Macromolecule
type: Class
subclass of: Biomolecule
definition: A very large molecule, such as protein, commonly created by polymerization of smaller subunits (monomers). They are typically composed of thousands of atoms or more. The most common macromolecules in biochemistry are biopolymers (nucleic acids, proteins, carbohydrates and polyphenols) and large non-polymeric molecules (such as lipids and macrocycles).

mono benzyl phthalate (BzBP)
notation: MBP
type: Class
subclass of: Phthalate

E-Cigarette Use
type: QualityVariable
type: Class
subclass of: Active Smoker

Below LOD, results repeated and confirmed (37, 33)
type: Class
subclass of: SIO_001167

Pregnancy Sample
definition: A sample that is taken at or near pregnancy or birth.
subclass of: Biospecimen
type: Class

Behavioral Experimental Paradigm Condition
type: Class
subclass of: Neurocognitive Assessment

Hemoglobin
type: Class
definition: The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae), as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism.
subclass of: Protein
was approved by: PER-Jim-McCusker

Interleukin-9
notation: IL9
subclass of: Protein
type: Class

Fresh Vegetable Consumption
type: QualityValue
type: Class
definition: Whether or not Fresh Vegetables are consumed.
subclass of: Fresh Vegetable Consumption Frequency
was approved by: PER-Jeanette-Stingone
notation: 29

Kaufman ABC
subclass of: Neurocognitive Assessment
type: Class
definition: culturally fair, cognitive ability test for children

Alcohol Use
type: QualityValue
type: Class
notation: 83
definition: Uses Alcohol
subclass of: Alcohol, Tobacco, and Illicit Drug Use

Aunt
type: Class
definition: The sister of your father or mother or the wife of your uncle.
subclass of: Relative
notation: 191
type: QualityValue

N-Ac-S-(2-Hydrxy-3-butnyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCMB2
subclass of: Volatile Organic Compound
type: Class

Manganese
notation: Mn
type: Class
definition: MANGANESE is a trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
subclass of: Metal

Sample integrity/quality compromised preventing analysis
subclass of: SIO_001167
type: Class

Education Grade 2
notation: 114
type: Class
definition: Finished grade 2
type: QualityValue
subclass of: Some Elementary School

microgram per gram
notation: ug/g
type: SIO_000074

RNA Sequencing
subclass of: Nucleic Acid Sequencing
type: Class

microampere
notation: µA
type: SIO_000074

Education Grade 4
subclass of: Elementary School
type: QualityValue
definition: Finished grade 4
notation: 116
type: Class

Benzophenone-3
type: Class
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
subclass of: Environmental Phenol
notation: BP3
editorial note: Duplicate of OXB?

1-hydroxypyrene
notation: PYR1
type: Class
subclass of: PAH

Element
subclass of: Targeted Analyte
type: Class

Interleukin-8
notation: IL8
type: Class
subclass of: Biological Response

Environmental Phenol
subclass of: Targeted Analyte
type: Class

Run out-of-contol; insufficient sample for repeat analysis
subclass of: SIO_001167
type: Class

Arsenous ( III) Acid
type: Class
subclass of: Arsenic Species
notation: Arsenous (III) Acid

Pregnancy Cohort Study
subclass of: CohortStudy
type: Class

Predominantly fibrous material
subclass of: SIO_001167
type: Class

Some Elementary School
type: QualityValue
type: Class
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
definition: Attended Some Elementary School
notation: 86

microgram
type: SIO_000074
notation: µg

Experimental Group
type: QualityValue
definition: A study population that receives the intervention that is the focus of the study.
subclass of: Population Group
type: Class
notation: 201

N-Acetyl-S-(2, 2-dichlorovinyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: DCVMA22

Cell
subclass of: Biospecimen
type: Class

Monocyclohexyl phthalate
notation: MCHP
subclass of: Phthalate
type: Class

Conceiving
subclass of: SIO_000587
comment: to become pregnant with a child.
type: Class

N-Acetyl-S-(2-Carbxyethyl)-L-Cys(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCCEM
editorial note: To Do: align with CHEBI.
type: Class

Urine
subclass of: Bodily Fluid
type: Class
definition: Excretion that is the output of a kidney [database_cross_reference: http://en.wikipedia.org/wiki/Urine][database_cross_reference: https://github.com/geneontology/go-ontology/issues/11025]

hexadecanoic acid
definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
notation: C160
subclass of: Fatty Acid
type: Class

Behavioral Experimental Paradigm
subclass of: Neurocognitive Assessment
type: Class

Route Of Delivery
subclass of: Delivery Characteristics
type: Class
type: QualityVariable

Hispanic or Latino Ethnicity
notation: 47
type: Class
type: QualityValue
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term “Spanish origin” can also be used in addition to “Hispanic or Latino.”
was approved by: PER-Jeanette-Stingone
subclass of: Ethnicity

femtomolar
notation: fM
type: SIO_000074

Trans-Chlordane
notation: TCHL
type: Class
subclass of: Organochlorine Compound

deciliter
type: SIO_000074
notation: dl

C-reactive protein
definition: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
subclass of: Protein
type: Class

meter
type: SIO_000074
notation: m

native cell
type: Class
subclass of: Cell

environmental tobacco smoke exposure
subclass of: Alcohol, Tobacco, and Illicit Drug Use
notation: 153
type: Class
type: QualityValue

dyne per cm
notation: dyn/cm
type: SIO_000074

decibel
type: SIO_000074
notation: dB

cubic meter per kilogram
notation: m3/kg
type: SIO_000074

Phenotype
type: Class
subclass of: Health Outcome

Meconium
subclass of: Feces
definition: A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth. [database_cross_reference: BTO:0000838]
subclass of: Pregnancy Sample
type: Class

2-Methylhippuric acid
type: Class
notation: MHA2
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound

gram per cubic centimeter
type: SIO_000074
notation: g/cm3

weber
notation: Wb
type: SIO_000074

gram per mole
type: SIO_000074
notation: g/mol

Bathroom Count
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
subclass of: Room Count
type: Class
definition: Total Number of Bathrooms in the Home

Greater than 99th percentile
subclass of: SIO_001167
type: Class

Exposure Monitoring Instrument
was approved by: PER-Jim-McCusker
subclass of: PhysicalInstrument
definition: A physical instrument that monitors the environment for chemical exposures.
type: Class

Interfering substances present
type: Class
subclass of: SIO_001167

nanovolt
notation: nV
type: SIO_000074

Replicate
type: Class
subclass of: Analyte
definition: The value contains data for a repeat of the study sample

Aluminum
definition: ALUMINUM is a metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
notation: Al
subclass of: Metal
type: Class

United States of America
type: QualityValue
notation: 184

Specimen analyzed in singlicate for an assay that requires duplicates
subclass of: SIO_001167
type: Class

Dental Fillings
notation: 13
type: QualityValue
type: Class
subclass of: Oral Health

Bismuth
type: Class
definition: BISMUTH is a metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
notation: Bi
subclass of: Metal

tesla
notation: Tesla
type: SIO_000074

Stress Frequency
type: Class
was approved by: PER-Jeanette-Stingone
editorial note: Again, we might want to link this to a specific assessment?
subclass of: Mental Health
type: QualityVariable
subclass of: SIO_000475
definition: How frequently a person gets stressed.

Disease
type: Class
subclass of: Health Outcome
subclass of: SIO_010299

N-Ace-S-(2-hydroxypropyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCHP2
type: Class

Anatabine
subclass of: Tobacco Metabolite
type: Class
notation: ANAT

Molybdenum
type: Class
notation: Mo
subclass of: Metal
definition: MOLYBDENUM is a metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)

Conception
type: Class
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
subclass of: Beginning
subclass of: Restriction
  all values from: Class
    intersection of: Conceiving
  on property: inRelationTo
definition: When a sperm fertilizes an egg
subclass of: From Conception

Non-White Hispanic
type: Class
type: QualityValue
subclass of: Hispanic or Latino Ethnicity
definition: Non-White and Hispanic
subclass of: Non-White
notation: 146

Immunoturbidimetry
definition: An analytical technique that uses light scattering, a physical phenomenon resulting from the interaction of light with particles in solution, to measure the concentration of particles. The photometric signal is generated by a decrease in light intensity as a direct consequence of increasing turbidity in the reaction well. Immunoturbidimetry uses the classical antigen-antibody reaction. The antigen-antibody complexes are particles which can be optically detected by an photometer.
subclass of: SIO_001007
type: Class
was approved by: PER-Jim-McCusker

Value below LLOQ, no LOD provided
subclass of: SIO_001167
type: Class

Head
subclass of: SIO_010046
type: Class

Tobacco Cessation Intervention Group
type: Class
type: QualityValue
notation: 202
definition: A group receiving a tobacco cessation intervention that is being tested in a study.
subclass of: Experimental Group

Alcohol, Tobacco, and Illicit Drug Use
definition: Alcohol, Tobacco, and Illicit Drug Use Indicator Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class

N-Acetyl-S-(benzyl)-L-cysteine(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: VOCBMA
type: Class

Gray
type: SIO_000074
notation: Gy

Electron Capture Dissociation (ECD)
subclass of: TandemMassSpectrometry
type: Class

Home Ownership
definition: Who owns the home they live in.
subclass of: Demographic
type: QuantityVariable
type: Class

Turbid
subclass of: SIO_001167
type: Class

mono-isononyl phthalate
notation: mINP
type: Class
subclass of: Phthalate

Very turbid
type: Class
subclass of: SIO_001167

Freeze/Thaw Cycles Count
subclass of: SIO_000794
was approved by: PER-Jeanette-Stingone
definition: Number of Freeze/Thaw cycles.
type: QuantityVariable
type: Class

N-Ace-S-(2-Hydroxyethyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class
notation: VOCHEM

Austism Spectrum Disorder related condition
subclass of: Developmental Disorder of Mental Health
type: Class
type: QualityValue
definition: Quality refers to children who do not meet DSM criteria for ASD but have scores on ADOS and Mullens that suggest related outcome. All potential options seems to fall under this class from the Autism Ontology
notation: 150

mono (2-ethyl-5-hydroxyhexyl) phthalate
subclass of: Phthalate
notation: MEHHP
type: Class

Infrared Multiphoton Dissociation (IRMPD)
subclass of: TandemMassSpectrometry
type: Class

N-Ace-S-(N-methlcarbamoyl)-L-cys(ng/mL)
subclass of: Volatile Organic Compound
notation: VOCAMC
editorial note: To Do: align with CHEBI.
type: Class

Behavior Rating Inventory of Executive Function – Preschool Version
subclass of: Neurocognitive Assessment
definition: Standardized rating scale designed to specifically measure the range of executive function in preschool-aged children
type: Class

Education Grade 5
type: Class
definition: Finished grade 5
type: QualityValue
notation: 117
subclass of: Some Middle School

unit per milliliter
notation: U/ml
type: SIO_000074

4-hydroxybenzophenone
subclass of: Benzophenone
type: Class
notation: OH4BP

Circumference
type: Class
subclass of: Anthropometry
type: QuantityVariable

Bedroom Count
type: QuantityVariable
definition: Total Number of Bedrooms in the Home
was approved by: PER-Jeanette-Stingone
subclass of: Room Count
type: Class

volt
notation: Volt
type: SIO_000074

Mercapturic acid of benzene
subclass of: PAH
type: Class
notation: SPMA

terabyte
notation: TB
type: SIO_000074

picogram per milliliter
notation: pg/mL
type: SIO_000074

2-hydroxynaphthalene
notation: NAP2
subclass of: PAH
type: Class

million parts per microgram
type: SIO_000074
notation: x106 µL

mass volume percentage
type: SIO_000074
notation: (w/v)

From Birth
type: Class
subclass of: Relative Time
definition: A time in relation to a birth
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: birthing

Difference
type: Class
definition: Variables derived from taking the difference of two other variables. For example, the first difference of a time series {yt} is defined as Dyt = yt - yt-1
subclass of: SIO_000052

microgray
notation: µGy
type: SIO_000074

Platelet
definition: A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
subclass of: Blood Component
type: Class

gram per deciliter
notation: g/dl
type: SIO_000074

normal
notation: Norm
type: SIO_000074

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2_PHEN3
subclass of: Environmental Phenol
type: Class

2, 2', 4, 4', 5, 5'-Hexabromobiphenyl
type: Class
subclass of: Polybrominated Diphenyl Ether
notation: PBB153
editorial note: To Do: align with CHEBI.

nanogram per milliliter
notation: ng/ml
type: SIO_000074

oleic acid
subclass of: Fatty Acid
notation: C181N9
type: Class
definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.

Departure
type: Class
notation: 174
definition: The act of leaving a destination.
subclass of: Destination
type: QualityValue

mono-methyl phthalate
type: Class
notation: mMP
subclass of: Phthalate

Early Childhood Vigilance Test
type: Class
subclass of: Neurocognitive Assessment
definition: a computer-based assessment of sustained attention during which the child is required to watch a screen where various animated stimuli disappear and reappear

Trimethylarsine oxide
type: Class
notation: Trimethylarsine oxide
subclass of: Arsenic Species

Consumed Alcohol
type: QualityValue
type: Class
subclass of: Alcohol Use
notation: 52

Body Mass Index
definition: A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length
editorial note: Should we note that this is derived from height and weight? JS: I think so
subclass of: Class
  intersection of: Restriction
    some values from: Height
    on property: wasDerivedFrom
  intersection of: Restriction
    some values from: SIO_000279
    on property: wasDerivedFrom
type: Class
subclass of: SIO_000052
type: QuantityVariable
was approved by: PER-Jeanette-Stingone
subclass of: Anthropometry

angstrom
type: SIO_000074
notation: Ang

Boiler Count
type: Class
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
definition: A boiler is an object that heats up water. This attribute quantifies the number of boilers in the home.
type: QuantityVariable

Occasional E-Cigarette Use
type: Class
notation: 155
subclass of: E-Cigarette Use
type: QualityValue

Parental Health and Family History
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class
definition: Parental Health and Family History Indicator Class

Quadrapole Time-of-Flight Liquid Chromotography-Mass Spectrometry
type: Class
subclass of: Liquid Chromotography-Mass Spectrometery

milligram per liter
notation: mg/L
type: SIO_000074

diethylphosphate
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class
notation: DEP

Interleukin-21
type: Class
notation: IL21
subclass of: Protein

9-hydroxyphenanthrene
subclass of: PAH
type: Class
notation: PHEN9

Socioeconomic Status
definition: Socioeconomic Status Indicator Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
type: Class

N-Acetyl-S-(2-cyanoethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: CYMA
type: Class
subclass of: Volatile Organic Compound

Unusually high
type: Class
subclass of: SIO_001167

dimethyldithiophosphate
type: Class
notation: DMDP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite

2, 2'-dihydroxy-methoxybenzophenone
notation: BP8

Replicate Number
type: Class
definition: Replicate Number
subclass of: SampleIndicator

Short sample; sample probe picked up incomplete volume first time
subclass of: SIO_001167
type: Class

mole
type: SIO_000074
notation: mol

Multiplex real-time PCR
type: Class
subclass of: Polymerase Chain Reaction

square meter
notation: m2
type: SIO_000074

Methyl mercury (CH3Hg+)
type: Class
notation: CH3Hg
subclass of: Mercury Species

Biological Response
type: Class
subclass of: StudyIndicator
editorial note: abolic_SDD_v1.xlsx
definition: Indicator of biological response to environmental exposure

Neighborhood Characteristic
subclass of: StudyIndicator
type: Class
definition: Neighborhood Characteristic Indicator Class
was approved by: PER-Jeanette-Stingone

platelet count
type: Class
subclass of: SIO_000794

Maternal Weight Gain
subclass of: Pregnancy Characteristic
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: Weight
definition: The amount of weight gained during a pregnacy.

plaque forming unit per milliliter
type: SIO_000074
notation: pfu/ml

4, 4'-(1-phenylethylidene)bisphenol
notation: BPAP

millimole per liter
type: SIO_000074
notation: mmol/L

From Conception
type: Class
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
definition: A time in relation to a conception
subclass of: Relative Time

picomolal
type: SIO_000074
notation: pmolal

Iodine
subclass of: Element
definition: Iodine is a nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
notation: I
type: Class

Tellurium
definition: Tellurium. An element that is a member of the chalcogen family. TELLURIUM has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.
subclass of: Metal
type: Class
notation: Te

N-Acetyl-S-(n-propyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
notation: BPMA
editorial note: To Do: align with CHEBI.

neural cell
type: Class
subclass of: Cell

Fms-related tyrosine kinase 3 ligand
type: Class
notation: FLT3L
subclass of: Protein

disintegrations per minute
notation: dpm
type: SIO_000074

Phenanthrene tetrol
notation: PHET

megakaryocyte-erythroid progenitor cell

Perfluorohexane-1-sulphonic acid
type: Class
notation: PFHxS
subclass of: PFC

Gas Chromatography Instrument
subclass of: Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture (the relative amounts of such components can also be determined). In some situations, GC may help in identifying a compound. In preparative chromatography, GC can be used to prepare pure compounds from a mixture.
type: Class

SYNAPT G2-Si Mass Spectrometer
subclass of: Hydrogen–Deuterium Exchange Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

micron pixel
notation: µm pixel
type: SIO_000074

mono-2-ethyl-5- carboxypentyl terephthalate (DEHTP)
notation: MECPTP

Preschool Child Behavior Checklist Internalizing Subscale
definition: Subscale of preschool CBCL that assesses internalizing behaviors
type: Class
subclass of: Neurocognitive Assessment

Cellular debris present
subclass of: SIO_001167
type: Class

Never Married
subclass of: Unmarried
definition: Indicates a person who has never been married or whose marriages have been annulled.
type: QualityValue
type: Class
notation: 38

Initial concentration higher than the highest standard
subclass of: SIO_001167
type: Class

Triclocarban
notation: TCC
type: Class
subclass of: Environmental Phenol
definition: Triclocarban is a triclosan analogue with an antibacterial property. Triclocarban exerts its effect by inhibiting the activity of enoyl-(acyl-carrier protein) (ACP) reductase, widely distributed in bacteria, fungi and plants. ACP reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. As a result, this agent interrupts cell membrane synthesis and leads to bacterial growth inhibition.

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
notation: HPMA
type: Class

Mandelic acid(ng/mL)
notation: VOCMAD
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Fenton Preterm Growth Chart
subclass of: SIO_000442
definition: A growth chart adusted for gestational age
type: Class

Selenium
definition: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
notation: Se
subclass of: Metal
type: Class

Destination
type: QualityVariable
notation: Dest
type: Class
definition: A place to which one is traveling or to which something is sent.
subclass of: Healthcare Access

Initial concentration higher than the highest standard, insufficient volume for repeat analysis (93, 18)
type: Class
subclass of: SIO_001167

picovolt
notation: pV
type: SIO_000074

red blood cell count
subclass of: SIO_000794
type: Class

Age Equivalent
type: Class
definition: Age Equivalent is the individual's ability; skill, knowledge, or measurement expressed as the age at which most individuals reach the same level (age norm). The Age Norm is the average score of a particular test completed by children of a given chronological age.
subclass of: STATO_0000569
type: QuantityVariable

4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol
notation: NNAL
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite
type: Class

Parous
subclass of: Parity
type: Class
notation: 73
type: QualityValue

curie
type: SIO_000074
notation: Ci

Quit Smoking After Pregnancy
type: Class
definition: Quit Smoking After Pregnancy
subclass of: Pregnancy Characteristic
type: QualityValue
subclass of: Quit Smoking
subclass of: Prenatal Smoker
notation: 80

Solid-Phase Sandwich ELISA
type: Class
was approved by: PER-Jim-McCusker
subclass of: Sandwich ELISA

parts per hundred
notation: pph
type: SIO_000074

Cerebral Malaria
type: Class
type: QualityValue
notation: 126
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
subclass of: Malaria

milliunits per milliliter
notation: mU/ml
type: SIO_000074

4-Hydroxybenzoic acid
subclass of: Environmental Phenol
type: Class
notation: HB4

Object
type: Class
subclass of: ScienceIndicator

Lipemic
subclass of: SIO_001167
type: Class

Samples Arrived Thawed and Analyzed
subclass of: SIO_001167
type: Class

did not precipitate
subclass of: SIO_001167
type: Class

Interlocutory Marital Status
type: Class
type: QualityValue
definition: The condition existing when an order or judgement is considered temporary until either a specified period of time has passed or specific information is provided to assist in rendering a permanent decision.
notation: 44
subclass of: Marital Status

PCB28
notation: PCB28
type: Class
subclass of: Polychlorobiphenyl

4-hydroxychrysene
subclass of: PAH
type: Class
notation: CHRY4

Tissue
type: Class
subclass of: Biospecimen

Income 75001 to 90000
type: Class
notation: 164
definition: Personal or family annual income bwtween $75,001 and $90,000
type: QualityValue
subclass of: Household Income

Icteric
subclass of: SIO_001167
type: Class

femtoliter
notation: fl
type: SIO_000074

Overweight
subclass of: Body Weight Quality
type: QualityValue
notation: 71
subclass of: Restriction
  on property: isAttributeOf
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
    on property: hasAttribute
type: Class

Result repeated and confirmed
type: Class
subclass of: SIO_001167

N-acetyl-S-(2-cyanoethyl)-L-cyst(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCCYM
type: Class
subclass of: Volatile Organic Compound

2, 3, 5, 6-Tetrachlorophenol
definition: PHYSICAL DESCRIPTION: Leaflets (from ligroin) or light beige powder. (NTP, 1992)
type: Class
subclass of: Environmental Phenol
notation: TeCP2356

PFC
subclass of: Targeted Analyte
type: Class

microcurie per milliliter
type: SIO_000074
notation: µcurie/ml

megabyte
type: SIO_000074
notation: MB

count per molar second
notation: 1/Ms
type: SIO_000074

4-nitrophenol
notation: PNP

monoisononyl phthalate
editorial note: Duplicate of mINP?
subclass of: Phthalate
notation: MIP
type: Class

Room Count
was approved by: PER-Jeanette-Stingone
subclass of: Housing Characteristic
type: QuantityVariable
definition: Total Number of Rooms in the Home
type: Class
subclass of: SIO_000794

centimeter
type: SIO_000074
notation: cm

Perfluorodecanoic acid
subclass of: PFC
notation: PFDA
type: Class

mole fraction
notation: chi
type: SIO_000074

Stromelysin-2
type: Class
notation: MMP10
subclass of: Protein

kilogram
type: SIO_000074
notation: kg

mono-pentyl phthalate
type: Class
subclass of: Phthalate
notation: mPeP

pascal second
type: SIO_000074
notation: Pas

gram per milliliter
notation: g/ml
type: SIO_000074

kilovolt-hour
notation: kVh
type: SIO_000074

cubic centimeter
type: SIO_000074
notation: cm3

Mono-n-octyl phthalate
subclass of: Phthalate
type: Class
notation: MOP

2, 4, 5-Trichlorophenol
type: Class
subclass of: Environmental Phenol
definition: Exposure to 2, 4, 5-trichlorophenol may occur during its production or use as a pesticide. Acute (short-term) dermal exposure to 2, 4, 5-trichlorophenol may burn skin in humans. It also irritates the eyes, nose, pharynx, and lungs in humans. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of 2, 4, 5-trichlorophenol in humans. In one study, slight degenerative changes were observed in the liver and kidneys of rats chronically exposed to 2, 4, 5-trichlorophenol in their diet. EPA has classified 2, 4, 5-trichlorophenol as a Group D, not classifiable as to human carcinogenicity. PHYSICAL DESCRIPTION: Colorless needles, gray flakes or off-white lumpy solid. Phenolic odor. Formerly used as a fungicide and bactericide.
notation: TCP245

pixels per millimeter
type: SIO_000074
notation: p/mm

Failed negative control
subclass of: SIO_001167
type: Class

quantity of sample insufficient for analysis
type: Class
subclass of: SIO_001167

Sample frozen
subclass of: SIO_001167
type: Class

PAH
subclass of: Volatile Organic Compound
type: Class

3-methipurc acd, 4-methipurc acd(ng/mL)
type: Class
subclass of: Volatile Organic Compound
editorial note: To Do: align with CHEBI.
notation: VOC34M

kilobasepair
notation: kbp
type: SIO_000074

cis-vaccenic acid
definition: The cis isomer of vaccenic acid.
subclass of: Fatty Acid
notation: C181N7
type: Class

Hexachlorobenzene
notation: HCB
type: Class
subclass of: Organochlorine Compound

degree Celsius
type: SIO_000074
notation: C

GO_0016265
deprecated: true

Metalloproteinase inhibitor 2
type: Class
notation: TIMP2
subclass of: Protein

Niobium
subclass of: Metal
definition: Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)
notation: Nb
type: Class

Benzophenone-1
subclass of: Benzophenone
type: Class
notation: BP1

Ever Smoked
was approved by: PER-Jeanette-Stingone
definition: The quality of having smoking in the past.
type: QualityValue
subclass of: Smoking Status
notation: 136
type: Class

mass density unit
notation: mdu
type: SIO_000074

Direct Mercury Analyzer
was approved by: PER-Jim-McCusker
subclass of: PhysicalInstrument
definition: Direct mercury analysis incorporates the following sequence: thermal decomposition, catalytic conversion, amalgamation, and atomic absorption spectrophotometry. Controlled heating stages are implemented to first dry and then thermally decompose a sample introduced into a quartz tube. A continuous flow of oxygen carries the decomposition products through a hot catalyst bed where halogens, nitrogen, and sulfur oxides are trapped. All mercury species are reduced to Hg(0) and are then carried along with reaction gases to a gold amalgamator where the mercury is selectively trapped. All nonmercury vapors and decomposition products are flushed from the system by the continuous flow of gas. The amalgamator is subsequently heated and releases all trapped mercury to the single-beam, fixed-wavelength atomic absorption spectrophotometer. Absorbance is measured at 253.7 nm as a function of mercury content
type: Class

foot candle
notation: ft-c
type: SIO_000074

Cognitive Task
type: Class
subclass of: Neurocognitive Assessment

HUC sample having discrepancy between fluorometer results and semi quantative Albustix test results
subclass of: SIO_001167
type: Class

Arsenic
notation: As
definition: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
subclass of: Metal
type: Class

kilogram per cubic meter
type: SIO_000074
notation: kg/m3

millicurie
type: SIO_000074
notation: mCi

microliters per minute
notation: µL/min
type: SIO_000074

katal per cubic meter
notation: kat/m3
type: SIO_000074

monooxoisononyl phthalate (DiNP)
notation: MONP

Non-Biological Relative
subclass of: Relative
definition: People that are considered relatives but are not related by blood. This includes relatives by marriage, adoption, or fosterage.
type: Class

Perfume Use
subclass of: Personal Product Use
type: Class
type: QualityValue
notation: 74
was approved by: PER-Jeanette-Stingone

Birth Outcome
type: Class
was approved by: PER-Jeanette-Stingone
subclass of: StudyIndicator
definition: Birth Outcomes Indicator Class

poise
type: SIO_000074
notation: Poise

meter per second
type: SIO_000074
notation: m/s

Microplate Reader
was approved by: PER-Jim-McCusker
subclass of: PhysicalInstrument
definition: Instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 6-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well (8 by 12 matrix) with a typical reaction volume between 100 and 200 µL per well. Higher density microplates (384- or 1536-well microplates) are typically used for screening applications, when throughput (number of samples per day processed) and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 µL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.
type: Class

cubic decimeter
notation: dm3
type: SIO_000074

dots per inch
notation: dpi
type: SIO_000074

milligram per gram
notation: mg/g
type: SIO_000074

Protein
subclass of: Biological Response
type: Class

Interleukin-2
type: Class
notation: IL2
subclass of: Protein

watt-hour
notation: Wh
type: SIO_000074

SIO_010058
notation: 131
type: QualityValue

6-chloronicotinic acid
notation: CINA6

dalton
notation: Da
type: SIO_000074

square centimeter
notation: cm2
type: SIO_000074

picomolar
type: SIO_000074
notation: pM

Age
subclass of: Demographic
type: QuantityVariable
type: Class

count unit
type: SIO_000074
notation: count

Hemolyzed (covers all three levels) and lipemic
subclass of: SIO_001167
type: Class

California
type: QualityValue
notation: 185

parts per trillion
notation: ppt
type: SIO_000074

Enzyme Immunoassay
type: Class
subclass of: Immunoassay

roentgen
type: SIO_000074
notation: Roentgen

cubic meter per mole
notation: m3/mol
type: SIO_000074

2, 2'-bis(4-hydroxyphenyl)butane
notation: BPB

Overloaded filter
type: Class
subclass of: SIO_001167

PCB118
type: Class
notation: PCB118
subclass of: Polychlorobiphenyl

centiRay
type: SIO_000074
notation: cR

Attribute
type: Class
subclass of: ScienceIndicator

newton per meter
type: SIO_000074
notation: N/m

UBERON_0036255
deprecated: true

SIO_000784
type: QualityValue
notation: 109

Electron-Detachment Dissociation (EDD)
subclass of: TandemMassSpectrometry
type: Class

radian per second per second
type: SIO_000074
notation: alpha

3-Hydroxypropyl-1-methyl mercapturic acid + 3-Hydroxypropyl-2-methyl mercapturic acid + 3-Hydroxypropyl-3-methyl mercapturic acid
notation: HMPMA

Cell

esophageal disease
subclass of: SIO_010299
type: Class

Kaufman ABC Sequence Subscale
definition: Subscale of Kaufman ABC designed to measure the ability to solve problems by remembering and using an ordered series of images or ideas
subclass of: Neurocognitive Assessment
type: Class

SO_0000000
deprecated: true

rest: nil
first:
  min exclusive: 25.0

rest: nil
first:
  max exclusive: 25

Datatype
intersection of: Datatype
  on datatype: float
  with restrictions:
    min exclusive: 18.5
intersection of: Datatype
  with restrictions:
    max exclusive: 25.0
  on datatype: float

Restriction
on property: hasValue
all values from: Datatype
  with restrictions:
    min inclusive: 15
  on datatype: integer

Restriction
on property: hasValue
all values from: Datatype
  on datatype: integer
  with restrictions:
    max exclusive: 15

Datatype
with restrictions:
  min exclusive: 29.9
on datatype: float

first:
  max exclusive: 25.0
rest: nil

first: Datatype
  with restrictions:
    max exclusive: 29.9
  on datatype: float
rest: nil

Datatype
with restrictions:
  min exclusive: 25
on datatype: integer

min exclusive: 25.0

Datatype
on datatype: float
with restrictions:
  max exclusive: 18.5